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The map label for this gene is garD [H]

Identifier: 138895510

GI number: 138895510

Start: 1982499

End: 1983665

Strand: Reverse

Name: garD [H]

Synonym: GTNG_1858

Alternate gene names: 138895510

Gene position: 1983665-1982499 (Counterclockwise)

Preceding gene: 138895511

Following gene: 138895509

Centisome position: 55.87

GC content: 51.5

Gene sequence:

>1167_bases
ATGAAGACCGCTCAATTTTGGGGGTATAGACGCCCTGATGGCCGGGTCGGAGTTCGAAACCATGTGCTGATTTTGCCGAC
GATTGTCTGCGCGACCCAAGCAGCGAAACAGGTGACAGAGCTCGTCCACGGTACCGTCTCCTTCATTCATCAGCATGGGT
GCGCTCAAGTTGGAGCCGATTATGAACAAACGTTCCGTACGTACGTTGGCATGGGAACGAACCCGAATGTGTACGGTGTA
GTAGTGATGGGACTTGGCTGTGAAACTCACCAAGGAAGAAGCGTGGCTCAGGAAATTGCCAAAAGCGGCAAGCCCGTTGA
GCTCGTGTCGATTCAAAACCATGGAGGAACCCTTGGCGCGATCGCTGAGGCGGCAAGAATTGCCGCTCAAATGGTGCAAG
ACGCTTCCGCTTTGGTGCGCGAACCGTTTGACGTCAGCGAATTGATCGTAGGAACTGAATGTGGGGGATCGGATGCATGT
TCCGGGCTTTCCGCTAACCCAGCGGTCGGATATGTGAGCGATATGATCGTCGACCGAGGAGGAACAGCCATTTTAGCGGA
AACGACAGAATTGATTGGGGCAGAGCACCTTCTAGCCAATCGGGCTGTAGATGACCGGGTGGCTAAAAAGGTGTACGAGG
TGATCGAGGCCATGGAAAAGCGTGCGATTGCAATGGGAGTAGATATTCGTACTGGAAATCCGAGCCCCGGAAATCGAAAA
GGAGGGCTTACAACTCTTGAAGAGAAATCGCTCGGGGCGGCGGCCAAGGCCGGGACGAGACCGTTGCAAGAGTTGATTCA
TTATGCCGAACGGCCAACGAAAAAGGGACTAGTCTGGATGGATACTCCTGGGCACGACATTGAACAGCTGACAGGGATGG
TGGCTGGTGGAGCGCAAATTGTTCTGTTTACAAGTGGGCGCGGCACGCCGACCGGTTCGCCGATTGCGCCGGTTATTAAA
ATTGCGACGAATACCTCGATGTTTGAAAGAATGAGAGAAAATATGGATATCAATGCCGGTACGATCATTGAAGGGAAAGA
GTCGCTTGAGTCAGTGGGAAGAAGAATTTTCGATGAACTGCTTCTTACAGCTTCAGGGAAATTGACTAAATCTGAGATCT
TAAAACAGCATGATTTTGGCATTTGGAGAATCGGCCCAACATTTTAA

Upstream 100 bases:

>100_bases
TACGGAGAAGTGATCGGCGTCGCCTCTAGCGATATTGCGGAAGGGGAGCATGTGCACGTGCATAACGTTGAAGGAAAAAG
GGGAAGGGGAGATAAGGAGC

Downstream 100 bases:

>100_bases
TCTCACCTAACCGTTTTTCATGTCGCTAGATAAAGCGAATACGCGGAGGGACTCATTATGAAAGAACTCGATGTGGTAAC
ATTCGGAGAAACAATGGTCT

Product: putative hydrolase C-terminus

Products: NA

Alternate protein names: GalcD [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MKTAQFWGYRRPDGRVGVRNHVLILPTIVCATQAAKQVTELVHGTVSFIHQHGCAQVGADYEQTFRTYVGMGTNPNVYGV
VVMGLGCETHQGRSVAQEIAKSGKPVELVSIQNHGGTLGAIAEAARIAAQMVQDASALVREPFDVSELIVGTECGGSDAC
SGLSANPAVGYVSDMIVDRGGTAILAETTELIGAEHLLANRAVDDRVAKKVYEVIEAMEKRAIAMGVDIRTGNPSPGNRK
GGLTTLEEKSLGAAAKAGTRPLQELIHYAERPTKKGLVWMDTPGHDIEQLTGMVAGGAQIVLFTSGRGTPTGSPIAPVIK
IATNTSMFERMRENMDINAGTIIEGKESLESVGRRIFDELLLTASGKLTKSEILKQHDFGIWRIGPTF

Sequences:

>Translated_388_residues
MKTAQFWGYRRPDGRVGVRNHVLILPTIVCATQAAKQVTELVHGTVSFIHQHGCAQVGADYEQTFRTYVGMGTNPNVYGV
VVMGLGCETHQGRSVAQEIAKSGKPVELVSIQNHGGTLGAIAEAARIAAQMVQDASALVREPFDVSELIVGTECGGSDAC
SGLSANPAVGYVSDMIVDRGGTAILAETTELIGAEHLLANRAVDDRVAKKVYEVIEAMEKRAIAMGVDIRTGNPSPGNRK
GGLTTLEEKSLGAAAKAGTRPLQELIHYAERPTKKGLVWMDTPGHDIEQLTGMVAGGAQIVLFTSGRGTPTGSPIAPVIK
IATNTSMFERMRENMDINAGTIIEGKESLESVGRRIFDELLLTASGKLTKSEILKQHDFGIWRIGPTF
>Mature_388_residues
MKTAQFWGYRRPDGRVGVRNHVLILPTIVCATQAAKQVTELVHGTVSFIHQHGCAQVGADYEQTFRTYVGMGTNPNVYGV
VVMGLGCETHQGRSVAQEIAKSGKPVELVSIQNHGGTLGAIAEAARIAAQMVQDASALVREPFDVSELIVGTECGGSDAC
SGLSANPAVGYVSDMIVDRGGTAILAETTELIGAEHLLANRAVDDRVAKKVYEVIEAMEKRAIAMGVDIRTGNPSPGNRK
GGLTTLEEKSLGAAAKAGTRPLQELIHYAERPTKKGLVWMDTPGHDIEQLTGMVAGGAQIVLFTSGRGTPTGSPIAPVIK
IATNTSMFERMRENMDINAGTIIEGKESLESVGRRIFDELLLTASGKLTKSEILKQHDFGIWRIGPTF

Specific function: D-galactarate metabolism; first step. [C]

COG id: COG2721

COG function: function code G; Altronate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uxaA family [H]

Homologues:

Organism=Escherichia coli, GI1789516, Length=382, Percent_Identity=40.5759162303665, Blast_Score=244, Evalue=1e-65,
Organism=Escherichia coli, GI1789475, Length=392, Percent_Identity=35.2040816326531, Blast_Score=228, Evalue=5e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007392
- InterPro:   IPR017654
- InterPro:   IPR013974 [H]

Pfam domain/function: PF04295 GD_AH_C; PF08666 SAF [H]

EC number: =4.2.1.42 [H]

Molecular weight: Translated: 41376; Mature: 41376

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTAQFWGYRRPDGRVGVRNHVLILPTIVCATQAAKQVTELVHGTVSFIHQHGCAQVGAD
CCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCC
YEQTFRTYVGMGTNPNVYGVVVMGLGCETHQGRSVAQEIAKSGKPVELVSIQNHGGTLGA
HHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCHHH
IAEAARIAAQMVQDASALVREPFDVSELIVGTECGGSDACSGLSANPAVGYVSDMIVDRG
HHHHHHHHHHHHHHHHHHHHCCCCHHHHEEECCCCCCHHCCCCCCCCCHHHHHHHHHCCC
GTAILAETTELIGAEHLLANRAVDDRVAKKVYEVIEAMEKRAIAMGVDIRTGNPSPGNRK
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCC
GGLTTLEEKSLGAAAKAGTRPLQELIHYAERPTKKGLVWMDTPGHDIEQLTGMVAGGAQI
CCCCEEHHHHCCHHHHCCCHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHCCCEEE
VLFTSGRGTPTGSPIAPVIKIATNTSMFERMRENMDINAGTIIEGKESLESVGRRIFDEL
EEEECCCCCCCCCCCCHHEEEECCHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHH
LLTASGKLTKSEILKQHDFGIWRIGPTF
HHHCCCCCCHHHHHHHHCCCEEEECCCC
>Mature Secondary Structure
MKTAQFWGYRRPDGRVGVRNHVLILPTIVCATQAAKQVTELVHGTVSFIHQHGCAQVGAD
CCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCC
YEQTFRTYVGMGTNPNVYGVVVMGLGCETHQGRSVAQEIAKSGKPVELVSIQNHGGTLGA
HHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCHHH
IAEAARIAAQMVQDASALVREPFDVSELIVGTECGGSDACSGLSANPAVGYVSDMIVDRG
HHHHHHHHHHHHHHHHHHHHCCCCHHHHEEECCCCCCHHCCCCCCCCCHHHHHHHHHCCC
GTAILAETTELIGAEHLLANRAVDDRVAKKVYEVIEAMEKRAIAMGVDIRTGNPSPGNRK
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCC
GGLTTLEEKSLGAAAKAGTRPLQELIHYAERPTKKGLVWMDTPGHDIEQLTGMVAGGAQI
CCCCEEHHHHCCHHHHCCCHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHCCCEEE
VLFTSGRGTPTGSPIAPVIKIATNTSMFERMRENMDINAGTIIEGKESLESVGRRIFDEL
EEEECCCCCCCCCCCCHHEEEECCHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHH
LLTASGKLTKSEILKQHDFGIWRIGPTF
HHHCCCCCCHHHHHHHHCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503; 2407727; 9772162; 10762278 [H]