Click here to switch to the map view.

The map label for this gene is dctR [H]

Identifier: 138895491

GI number: 138895491

Start: 1959871

End: 1960557

Strand: Reverse

Name: dctR [H]

Synonym: GTNG_1839

Alternate gene names: 138895491

Gene position: 1960557-1959871 (Counterclockwise)

Preceding gene: 138895492

Following gene: 138895490

Centisome position: 55.22

GC content: 46.58

Gene sequence:

>687_bases
ATGATTCGCGTGCTGATTATCGAAGACGACCATCGTATTGCCGAGATTAACCGACGCTTTGTGGAAAAAGTAGAAGGGTA
TGAAGTTGTTGGCATTGCCACGAACGCCGAAGAGGCAAGGGAACTGACCGAAGTGTTGCGGCCGGACGTATTGTTGCTTG
ACGTCTATTTTCCAGATATGAACGGTATCTCTTTCTTGAAATGGGTTCGTCAACGTTTTTCTAATATTGATATTATCATG
ATCACAGCAGCACGGGAAATTGATACGTTGAAACAGGCGCTGCATGGCGGAGTATTTGATTATATCATCAAACCGATTAT
GTTCAACCGTTTTGCCGAAACATTAAATCGCTATAAAGATTACCATGACAAAATGCAGCAATGGATGAAAGAGAAAGAAT
GGATCGGCCAAGAAGATGTCGATGAACTGATAGGGAGAGAACTGTCGGCCAAGGAGCAGCCCTCGTTGCCAAAGGGCATC
CAGCCGTTGACGCTTGAAAAAGTGCTAGTTGTCGTGAAACAATGCCGGGATGGAGTGACGGCCGAAGAAGTCGGACAGCA
AATTGGTATGAGCCGAACGACGGCTCGTCGGTATTTAGAGTACCTTGTCTCCACAGGACAAGTGCTGGCCGATATTGCTT
ATGGATCGGTCGGACGCCCGGAACGGATTTATAGAAAGAGAGGGTAA

Upstream 100 bases:

>100_bases
CACTTATCAATCGAAACAAGGGGAGGGAACGGTGTTTACCGTCATTATTCCGAAGCAGCTGGCCGACGCCAATCACCATT
GAGAGGGGGATAGAGAGTCG

Downstream 100 bases:

>100_bases
GCAAGGTTCTCGTTTAGAAAAGCATAGCGGCTTCCATATGCACAAAGAAAGCGGGGGAGAGTGTTGGCCGTTTTTAGTGG
CATTTTGCTTCAAGTGATGG

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MIRVLIIEDDHRIAEINRRFVEKVEGYEVVGIATNAEEARELTEVLRPDVLLLDVYFPDMNGISFLKWVRQRFSNIDIIM
ITAAREIDTLKQALHGGVFDYIIKPIMFNRFAETLNRYKDYHDKMQQWMKEKEWIGQEDVDELIGRELSAKEQPSLPKGI
QPLTLEKVLVVVKQCRDGVTAEEVGQQIGMSRTTARRYLEYLVSTGQVLADIAYGSVGRPERIYRKRG

Sequences:

>Translated_228_residues
MIRVLIIEDDHRIAEINRRFVEKVEGYEVVGIATNAEEARELTEVLRPDVLLLDVYFPDMNGISFLKWVRQRFSNIDIIM
ITAAREIDTLKQALHGGVFDYIIKPIMFNRFAETLNRYKDYHDKMQQWMKEKEWIGQEDVDELIGRELSAKEQPSLPKGI
QPLTLEKVLVVVKQCRDGVTAEEVGQQIGMSRTTARRYLEYLVSTGQVLADIAYGSVGRPERIYRKRG
>Mature_228_residues
MIRVLIIEDDHRIAEINRRFVEKVEGYEVVGIATNAEEARELTEVLRPDVLLLDVYFPDMNGISFLKWVRQRFSNIDIIM
ITAAREIDTLKQALHGGVFDYIIKPIMFNRFAETLNRYKDYHDKMQQWMKEKEWIGQEDVDELIGRELSAKEQPSLPKGI
QPLTLEKVLVVVKQCRDGVTAEEVGQQIGMSRTTARRYLEYLVSTGQVLADIAYGSVGRPERIYRKRG

Specific function: Member of the two-component regulatory system dctS/dctR. Essential for expression of dctP [H]

COG id: COG4565

COG function: function code KT; Response regulator of citrate/malate metabolism

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786838, Length=225, Percent_Identity=36.4444444444444, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1790566, Length=231, Percent_Identity=33.7662337662338, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI1788550, Length=106, Percent_Identity=35.8490566037736, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1790299, Length=98, Percent_Identity=32.6530612244898, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR013196
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF08279 HTH_11; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 26434; Mature: 26434

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRVLIIEDDHRIAEINRRFVEKVEGYEVVGIATNAEEARELTEVLRPDVLLLDVYFPDM
CEEEEEEECCHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHCCCEEEEEEECCCC
NGISFLKWVRQRFSNIDIIMITAAREIDTLKQALHGGVFDYIIKPIMFNRFAETLNRYKD
CCHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
YHDKMQQWMKEKEWIGQEDVDELIGRELSAKEQPSLPKGIQPLTLEKVLVVVKQCRDGVT
HHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
AEEVGQQIGMSRTTARRYLEYLVSTGQVLADIAYGSVGRPERIYRKRG
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCC
>Mature Secondary Structure
MIRVLIIEDDHRIAEINRRFVEKVEGYEVVGIATNAEEARELTEVLRPDVLLLDVYFPDM
CEEEEEEECCHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHCCCEEEEEEECCCC
NGISFLKWVRQRFSNIDIIMITAAREIDTLKQALHGGVFDYIIKPIMFNRFAETLNRYKD
CCHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
YHDKMQQWMKEKEWIGQEDVDELIGRELSAKEQPSLPKGIQPLTLEKVLVVVKQCRDGVT
HHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
AEEVGQQIGMSRTTARRYLEYLVSTGQVLADIAYGSVGRPERIYRKRG
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]