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The map label for this gene is arsB [H]

Identifier: 138895257

GI number: 138895257

Start: 1686987

End: 1688048

Strand: Direct

Name: arsB [H]

Synonym: GTNG_1599

Alternate gene names: 138895257

Gene position: 1686987-1688048 (Clockwise)

Preceding gene: 138895256

Following gene: 138895258

Centisome position: 47.52

GC content: 40.87

Gene sequence:

>1062_bases
ATGAATAATACGGGGAAAAAACGTCTATCGTTCTTGGATCGATACCTAACGATTTGGATTTTCCTTGCTATGGCAGCAGG
AATTGGCTTAGGTTTCGTCTTTCCGGGCTTTGTAGACGGAATGAACAGTTTGCAGGTAGGAACCACATCGATTCCAATTG
CCATCGGCTTAATTTTAATGATGTATCCTCCGTTAGCAAAAGTTCGCTACGAGGAGATGGGACGCGTCTTTAAAAATGTG
AAAGTATTAGTGTTATCGCTCGTACAAAACTGGATTTTTGGACCGATTCTTATGTTTGTGTTGGCGATCGTATTCTTGCC
GGATAAACCGGAATACATGGTCGGACTCATCATGATCGGTCTGGCACGTTGTATTGCGATGGTGATTGTCTGGAATGATT
TAGCGAATGGAGATAGAGAGTACGCAGCTGGATTGGTGGCGTTTAACTCTGTATTCCAAATGCTATTTTACTCTGTTTAT
GCGTATGTGTTTGTGACAATCATTCCAGAATGGTTAGGACTAGAAGGTGCTGTCGTTCATATTACAATGATGGAAGTCGC
TAAGTCGGTGTTCATTTACTTAGGAATTCCGTTTCTTGGCGGAATGTTGACGCGCTTTTTGTTGGTAAAAGCAAAGGGCA
GACAATGGTATGAAAAAGTATTTATTCCAAAAATCAGCCCGATTACATTGATTTCTTTATTGTTTACGATTATTGTCATG
TTCTCTTTAAAAGGAGATGTTATCGTAAGTTTACCATTGGATGTAGTGAGAGTTGCTATTCCATTGTTCATTTACTTTGT
GTTGATGTTCTTCGTTTCCTTCTTCATAGGGAAGAAATTTGGAGCGAACTACCCTGTAACCACCACACTTGCTTTTACAG
CCGGCAGTAATAACTTTGAGTTAGCGATTGCCGTAGCTGTTGGCGTGTTTGGGATCCATTCTGGTGCAGCATTTGCAGCT
GTTATTGGACCACTGGTGGAAGTGCCTGTCATGATTGCGTTAGTCAACGTGGCACTATGGTTTCAACGAAAATACTTTAA
AACAGAATCAGTATCATACTAA

Upstream 100 bases:

>100_bases
ACATATTCCAGATCAAACAGAGAATATTCGTAAGATTGAGGAAAACAACCCTACGCTCCGTTGTGGTTGTTAACCTACTA
ATTAAATTGGGAGAGAAAAA

Downstream 100 bases:

>100_bases
CAACAGAGGTGGAAGGAAACATGAAAAACAAAAAGATCATTTACTTCTTATGCACAGGTAACTCTTGCCGCAGCCAAATG
GCAGAAGGATGGGCAAAAAA

Product: arsenical-resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MNNTGKKRLSFLDRYLTIWIFLAMAAGIGLGFVFPGFVDGMNSLQVGTTSIPIAIGLILMMYPPLAKVRYEEMGRVFKNV
KVLVLSLVQNWIFGPILMFVLAIVFLPDKPEYMVGLIMIGLARCIAMVIVWNDLANGDREYAAGLVAFNSVFQMLFYSVY
AYVFVTIIPEWLGLEGAVVHITMMEVAKSVFIYLGIPFLGGMLTRFLLVKAKGRQWYEKVFIPKISPITLISLLFTIIVM
FSLKGDVIVSLPLDVVRVAIPLFIYFVLMFFVSFFIGKKFGANYPVTTTLAFTAGSNNFELAIAVAVGVFGIHSGAAFAA
VIGPLVEVPVMIALVNVALWFQRKYFKTESVSY

Sequences:

>Translated_353_residues
MNNTGKKRLSFLDRYLTIWIFLAMAAGIGLGFVFPGFVDGMNSLQVGTTSIPIAIGLILMMYPPLAKVRYEEMGRVFKNV
KVLVLSLVQNWIFGPILMFVLAIVFLPDKPEYMVGLIMIGLARCIAMVIVWNDLANGDREYAAGLVAFNSVFQMLFYSVY
AYVFVTIIPEWLGLEGAVVHITMMEVAKSVFIYLGIPFLGGMLTRFLLVKAKGRQWYEKVFIPKISPITLISLLFTIIVM
FSLKGDVIVSLPLDVVRVAIPLFIYFVLMFFVSFFIGKKFGANYPVTTTLAFTAGSNNFELAIAVAVGVFGIHSGAAFAA
VIGPLVEVPVMIALVNVALWFQRKYFKTESVSY
>Mature_353_residues
MNNTGKKRLSFLDRYLTIWIFLAMAAGIGLGFVFPGFVDGMNSLQVGTTSIPIAIGLILMMYPPLAKVRYEEMGRVFKNV
KVLVLSLVQNWIFGPILMFVLAIVFLPDKPEYMVGLIMIGLARCIAMVIVWNDLANGDREYAAGLVAFNSVFQMLFYSVY
AYVFVTIIPEWLGLEGAVVHITMMEVAKSVFIYLGIPFLGGMLTRFLLVKAKGRQWYEKVFIPKISPITLISLLFTIIVM
FSLKGDVIVSLPLDVVRVAIPLFIYFVLMFFVSFFIGKKFGANYPVTTTLAFTAGSNNFELAIAVAVGVFGIHSGAAFAA
VIGPLVEVPVMIALVNVALWFQRKYFKTESVSY

Specific function: Seems to confer resistance to arsenite by allowing cells to extrude this compound. Could be part of an arsenite extrusion pump [H]

COG id: COG0798

COG function: function code P; Arsenite efflux pump ACR3 and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ACR3 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6325459, Length=324, Percent_Identity=36.4197530864198, Blast_Score=171, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004706
- InterPro:   IPR002657 [H]

Pfam domain/function: PF01758 SBF [H]

EC number: NA

Molecular weight: Translated: 39230; Mature: 39230

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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EHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure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EHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7704261; 8969508; 9384377; 7489895; 9537360 [H]