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The map label for this gene is pgsA [H]

Identifier: 138894813

GI number: 138894813

Start: 1211887

End: 1212429

Strand: Direct

Name: pgsA [H]

Synonym: GTNG_1147

Alternate gene names: 138894813

Gene position: 1211887-1212429 (Clockwise)

Preceding gene: 138894812

Following gene: 138894814

Centisome position: 34.13

GC content: 50.46

Gene sequence:

>543_bases
ATGCTCATCCCATTTTTCTTGATCGTAATGCTTGTTCCGTTTGGATGGGGGAGCGTCCAAATCGGTAGGACGGAGCTCCC
GATCGCTCATCTTGTCGGCGCGCTCATTTTCATCATCGCTTCAACGACAGACTGGATTGACGGCTATTACGCCCGTAAAT
ACGGATTGGTGACAAATTTAGGGAAGTTTTTAGATCCGCTCGCCGATAAACTGCTTGTATCGGCAGCACTTATCGTGCTC
GTCGAGCTTGGTTTGGCTCCGGCTTGGATGGTGATCGTCATCATCAGTCGCGAGTTTGCCGTTACCGGGCTGCGGTTGGT
GCTCGCTGGCGAAGGGGAAGTTGTCGCGGCCAATATGCTAGGAAAAATTAAGACGTGGACACAAATTGTGGCGATTGCTG
CCTTGTTGCTACATAATTTTCCGTTTTCGCTCATCCCGTTCCCGTTCGCCGATTTGGCGCTTTGGGTGGCAGTGGTGTTC
ACCATTTGGTCTGGCTGGGACTACTTTGCGAAAAATAAACATGCTTTTGCCCATTCGAAATAG

Upstream 100 bases:

>100_bases
TTTTTTCAGAAAGGAAGCCGCTTCTTTGTCCGGATAGATGTTGAATTAGCGGAGGTAATTTGTTGTGAACTTGCCGAATA
AAATTACGGTAGCGCGCATT

Downstream 100 bases:

>100_bases
CCGGCGGGAAAGGGGGAACGTCCGTTGAATGCGGAAATCATTGCTGTTGGCTCCGAGCTGTTGCTCGGACAAATTGCCAA
TACGAACGCCCAGTTTTTGT

Product: phosphatidylglycerophosphate synthase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MLIPFFLIVMLVPFGWGSVQIGRTELPIAHLVGALIFIIASTTDWIDGYYARKYGLVTNLGKFLDPLADKLLVSAALIVL
VELGLAPAWMVIVIISREFAVTGLRLVLAGEGEVVAANMLGKIKTWTQIVAIAALLLHNFPFSLIPFPFADLALWVAVVF
TIWSGWDYFAKNKHAFAHSK

Sequences:

>Translated_180_residues
MLIPFFLIVMLVPFGWGSVQIGRTELPIAHLVGALIFIIASTTDWIDGYYARKYGLVTNLGKFLDPLADKLLVSAALIVL
VELGLAPAWMVIVIISREFAVTGLRLVLAGEGEVVAANMLGKIKTWTQIVAIAALLLHNFPFSLIPFPFADLALWVAVVF
TIWSGWDYFAKNKHAFAHSK
>Mature_180_residues
MLIPFFLIVMLVPFGWGSVQIGRTELPIAHLVGALIFIIASTTDWIDGYYARKYGLVTNLGKFLDPLADKLLVSAALIVL
VELGLAPAWMVIVIISREFAVTGLRLVLAGEGEVVAANMLGKIKTWTQIVAIAALLLHNFPFSLIPFPFADLALWVAVVF
TIWSGWDYFAKNKHAFAHSK

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=179, Percent_Identity=36.8715083798883, Blast_Score=91, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 19811; Mature: 19811

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIPFFLIVMLVPFGWGSVQIGRTELPIAHLVGALIFIIASTTDWIDGYYARKYGLVTNL
CHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
GKFLDPLADKLLVSAALIVLVELGLAPAWMVIVIISREFAVTGLRLVLAGEGEVVAANML
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEEEECCCCEEEHHHH
GKIKTWTQIVAIAALLLHNFPFSLIPFPFADLALWVAVVFTIWSGWDYFAKNKHAFAHSK
HHHHHHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCC
>Mature Secondary Structure
MLIPFFLIVMLVPFGWGSVQIGRTELPIAHLVGALIFIIASTTDWIDGYYARKYGLVTNL
CHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
GKFLDPLADKLLVSAALIVLVELGLAPAWMVIVIISREFAVTGLRLVLAGEGEVVAANML
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEEEECCCCEEEHHHH
GKIKTWTQIVAIAALLLHNFPFSLIPFPFADLALWVAVVFTIWSGWDYFAKNKHAFAHSK
HHHHHHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7750561; 9384377 [H]