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The map label for this gene is cheB [H]

Identifier: 138894761

GI number: 138894761

Start: 1157160

End: 1158206

Strand: Direct

Name: cheB [H]

Synonym: GTNG_1095

Alternate gene names: 138894761

Gene position: 1157160-1158206 (Clockwise)

Preceding gene: 138894760

Following gene: 138894762

Centisome position: 32.59

GC content: 55.59

Gene sequence:

>1047_bases
ATGAAGACGATCAAGGTGCTTGTTGTCGATGACTCGGCGTTTATGCGCAAATGGATCAGCGATTTTTTGTCCGAACACCC
GCGCCTTGAAGTCATTGGAACGGCCCGCAATGGTCAAGAGGCGCTTGAGAAAATCGCTGTTCTTCACCCTGATGTTGTGA
CGCTCGACGTCGAAATGCCAGTGATGGACGGACTGGAAACATTGCGGCATATCATGGAGAAGAAGCCGTTGCCGGTCGTC
ATGGTATCAAGCACGACGAAGGAAGGGGCGGAAAATACGGTAACCGCCATGCAATATGGGGCCGTTGATTTTGTGGCGAA
ACCATCTGGTTCGCTTTCGCTTGATTTATACAAAGTGAGGGATGAACTAGTCCGAAAAGTGTTGCATGCAAGCGAAGCGA
ACATAAGGGCGCTCACCGTCCGGCGCTCGAAAGTCGGACCTTGGCGTTCACTCGACAAAACGGCGCACGTCGGAAAAGCG
ATCGTCGCCATCGGCACCTCAACCGGCGGCCCACGAGCCTTAGAAACCGTGCTGACGCAGCTGCCGCCCGATTTGGCCGC
TCCAGTTGTCATCGTCCAGCATATGCCGAAAGGATTTACGAAATCGCTTGCCAACCGGCTGGACGCACTATCCGCCATAA
CTGTCAAAGAGGCAGAAGATGGGGAGGTGCTGCGAAATGGCACTGCTTATATCGCCCCAGGCGGTGTTCATCTTGCCGTC
AGGGAGGAAAACGGTGTGCTGAAAGCCCATTTTGATGCGTCGCCGCCGCGCGCCGGCCACCGCCCAGCCGTTGACGTGTT
GTTCGAATCACTTGCCGCCATTCACCACTGCCGGAAAGTGGTGGTAATCATGACCGGAATGGGAGCAGATGGGACGAAGG
GACTGAAAAAGTTGAAAGAAAGCGGAGACGTGGAAGCGATCGCCGAAGCGCGCGAGACAGCAGTCATTTATGGGATGCCG
AGGGCGGCGATCGAGACCGGTGTCATCGATGTCATTACTCCGCTTGACGGCATTGCCGCCGCCATCGTCCAATCGATCGG
GGAATGA

Upstream 100 bases:

>100_bases
GGCATTCCGTTATGCGCCGCAGCGGGAGGAAGGGACGGAGCGGGCGAGTCGCTTTTTTGCCAAACTGCGCCAACTTTTCC
TAGAAAGGTAGAGACGGACA

Downstream 100 bases:

>100_bases
GGGGGAACATGGGATGGATATGAGTCAATACTTAGACATCTTTATTGATGAAAGCAAGGAACATCTGCAAACGATCAACG
AGCGGCTGCTTGAACTCGAA

Product: chemotaxis-specific methylesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MKTIKVLVVDDSAFMRKWISDFLSEHPRLEVIGTARNGQEALEKIAVLHPDVVTLDVEMPVMDGLETLRHIMEKKPLPVV
MVSSTTKEGAENTVTAMQYGAVDFVAKPSGSLSLDLYKVRDELVRKVLHASEANIRALTVRRSKVGPWRSLDKTAHVGKA
IVAIGTSTGGPRALETVLTQLPPDLAAPVVIVQHMPKGFTKSLANRLDALSAITVKEAEDGEVLRNGTAYIAPGGVHLAV
REENGVLKAHFDASPPRAGHRPAVDVLFESLAAIHHCRKVVVIMTGMGADGTKGLKKLKESGDVEAIAEARETAVIYGMP
RAAIETGVIDVITPLDGIAAAIVQSIGE

Sequences:

>Translated_348_residues
MKTIKVLVVDDSAFMRKWISDFLSEHPRLEVIGTARNGQEALEKIAVLHPDVVTLDVEMPVMDGLETLRHIMEKKPLPVV
MVSSTTKEGAENTVTAMQYGAVDFVAKPSGSLSLDLYKVRDELVRKVLHASEANIRALTVRRSKVGPWRSLDKTAHVGKA
IVAIGTSTGGPRALETVLTQLPPDLAAPVVIVQHMPKGFTKSLANRLDALSAITVKEAEDGEVLRNGTAYIAPGGVHLAV
REENGVLKAHFDASPPRAGHRPAVDVLFESLAAIHHCRKVVVIMTGMGADGTKGLKKLKESGDVEAIAEARETAVIYGMP
RAAIETGVIDVITPLDGIAAAIVQSIGE
>Mature_348_residues
MKTIKVLVVDDSAFMRKWISDFLSEHPRLEVIGTARNGQEALEKIAVLHPDVVTLDVEMPVMDGLETLRHIMEKKPLPVV
MVSSTTKEGAENTVTAMQYGAVDFVAKPSGSLSLDLYKVRDELVRKVLHASEANIRALTVRRSKVGPWRSLDKTAHVGKA
IVAIGTSTGGPRALETVLTQLPPDLAAPVVIVQHMPKGFTKSLANRLDALSAITVKEAEDGEVLRNGTAYIAPGGVHLAV
REENGVLKAHFDASPPRAGHRPAVDVLFESLAAIHHCRKVVVIMTGMGADGTKGLKKLKESGDVEAIAEARETAVIYGMP
RAAIETGVIDVITPLDGIAAAIVQSIGE

Specific function: Involved in the modulation of the chemotaxis system; catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR [H]

COG id: COG2201

COG function: function code NT; Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788192, Length=351, Percent_Identity=40.1709401709402, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI1788550, Length=115, Percent_Identity=33.9130434782609, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR008248
- InterPro:   IPR000673
- InterPro:   IPR001789 [H]

Pfam domain/function: PF01339 CheB_methylest; PF00072 Response_reg [H]

EC number: =3.1.1.61 [H]

Molecular weight: Translated: 37252; Mature: 37252

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50122 CHEB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTIKVLVVDDSAFMRKWISDFLSEHPRLEVIGTARNGQEALEKIAVLHPDVVTLDVEMP
CCEEEEEEECCHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCCEEEEEECCC
VMDGLETLRHIMEKKPLPVVMVSSTTKEGAENTVTAMQYGAVDFVAKPSGSLSLDLYKVR
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHCCEEEEECCCCCCEEHHHHHH
DELVRKVLHASEANIRALTVRRSKVGPWRSLDKTAHVGKAIVAIGTSTGGPRALETVLTQ
HHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHCEEEEEEECCCCCHHHHHHHHHH
LPPDLAAPVVIVQHMPKGFTKSLANRLDALSAITVKEAEDGEVLRNGTAYIAPGGVHLAV
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEECCCCCCCEECCEEEEECCCEEEEE
REENGVLKAHFDASPPRAGHRPAVDVLFESLAAIHHCRKVVVIMTGMGADGTKGLKKLKE
ECCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHH
SGDVEAIAEARETAVIYGMPRAAIETGVIDVITPLDGIAAAIVQSIGE
CCCHHHHHHHHHCEEEEECCHHHHHCCCCEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKTIKVLVVDDSAFMRKWISDFLSEHPRLEVIGTARNGQEALEKIAVLHPDVVTLDVEMP
CCEEEEEEECCHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCCEEEEEECCC
VMDGLETLRHIMEKKPLPVVMVSSTTKEGAENTVTAMQYGAVDFVAKPSGSLSLDLYKVR
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHCCEEEEECCCCCCEEHHHHHH
DELVRKVLHASEANIRALTVRRSKVGPWRSLDKTAHVGKAIVAIGTSTGGPRALETVLTQ
HHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHCEEEEEEECCCCCHHHHHHHHHH
LPPDLAAPVVIVQHMPKGFTKSLANRLDALSAITVKEAEDGEVLRNGTAYIAPGGVHLAV
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEECCCCCCCEECCEEEEECCCEEEEE
REENGVLKAHFDASPPRAGHRPAVDVLFESLAAIHHCRKVVVIMTGMGADGTKGLKKLKE
ECCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHH
SGDVEAIAEARETAVIYGMPRAAIETGVIDVITPLDGIAAAIVQSIGE
CCCHHHHHHHHHCEEEEECCHHHHHCCCCEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA