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The map label for this gene is speA [H]

Identifier: 138894599

GI number: 138894599

Start: 1000873

End: 1002345

Strand: Reverse

Name: speA [H]

Synonym: GTNG_0929

Alternate gene names: 138894599

Gene position: 1002345-1000873 (Counterclockwise)

Preceding gene: 138894604

Following gene: 138894597

Centisome position: 28.23

GC content: 50.92

Gene sequence:

>1473_bases
TTGTCGCAACTCGAGACACCATTGTTTACCGGGCTGTTGGAACACGTAAAAAAAGATCCAATCCAATTTCACATTCCCGG
TCATAAAAAGGGAGCAGGTATGGATCCGGAATTTCGCGCCTTCATCGGAGAAAACGCCTTGGCGATCGATTTAATCAACA
TCAGCCCGCTCGATGACTTGCACCATCCGAAAGGGATGATTAAGCGGGCGCAAGAGCTCGCTGCTGAAGCGTTCGGCGCC
GATTATACATTTTTCTCAGTGCAGGGGACAAGTGGCGCGATTATGACGATGATTATGTCGGTCGCTGGACCGGGCGATAA
AATTATTGTGCCGCGCAATGTCCATAAATCCGTCATGTCGGCGATCGTGTTTTCCGGGGCCACACCGATTTTCATCCACC
CGGAAATCGATAAGGAGCTTGGCATTTCTCACGGTATCACTCCCCAAGCGGTCGAAAAAGCGCTTGAACAGCACCCGGAT
GCCAAAGGGGTGCTTGTCATCAACCCGACATACTTTGGGATTGCCGGCGATTTGAAAAAAATCGTAGAGATTGCTCATTC
ATACAATGTCCCAGTGCTCGTCGACGAAGCGCACGGAGTGCACATCCACTTCCACGAAGATTTGCCGCTCTCGGCGATGC
AAGCCGGTGCTGATATGGCGGCGACCAGCGTTCATAAACTCGGTGGATCACTAACCCAAAGCTCGATCTTGAACGTGCGC
GAAGGGCTCGTTTCCGCCAAACATGTGCAAGCTGTTTTGAGCATGCTCACAACGACGTCGACATCGTATTTGCTGCTCGC
ATCACTCGATGTTGCCCGCAAACAGCTGGCGACGAAAGGTCGGGAACTCATTGACCAAGCGATCCGCCTTGCCGACTGGA
CGCGGGAGCAAATCAATCAGATTCCGTATTTATATTGTGTTGGCAAAGAAATTTTAGGGACAGAAGCGACATACGACTAC
GATCCAACGAAGCTGATCATTTCCGTCAAAGAGCTCGGATTGACTGGTCATGACGTCGAGCAATGGCTCCGAGAAACGTA
CAACATCGAAGTAGAGCTTTCCGATTTATATAACATTTTGTGCATCATCACTCCGGGTGATAGCGAGCGCGAAGCCAGCC
TGCTCATCGAGGCGCTCCGCCGCTTATCAGAGCAATTCAGCCACCAAGCTGAAGAAGGAATAAAACCGAAAGTGCTGCTT
CCAGATATCCCGGCGCTTGCCTTGACGCCGCGTGATGCGTTTTACGCCGAAACGGAAGTTGTGCCGTTTCACGAGTCGGT
AGGCCGAATTATCGCTGAGTTTGTGATGGTGTACCCGCCGGGCATCCCGATCTTTATCCCTGGCGAGATCATTACTGAGG
AAAACTTGAAGTATATCGAAACGAATTTGGCCGCTGGCCTCCCTGTCCAAGGTCCAGAAGATGATACACTGCAATCGTTG
CGTGTGATTAAAGAATATAAACCGATTCGCTGA

Upstream 100 bases:

>100_bases
TTTTCCTTTTTCACATAGCATTCATTTCTTCTTTGCAAACGAAAAAATAAATGCTATAATGCACTTGTTTTATTTTAAGG
TAAAGAGGTGTGAAAAACCA

Downstream 100 bases:

>100_bases
CCGCACAAGCTAGGTAACTACTAGCTTGTGCTTTTTTTGTGCAAAATAAATGGCGCACATGTGCCCCTTTCACATGTGCG
CCTATCCATTCCTTCCCCCG

Product: lysine decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 489

Protein sequence:

>490_residues
MSQLETPLFTGLLEHVKKDPIQFHIPGHKKGAGMDPEFRAFIGENALAIDLINISPLDDLHHPKGMIKRAQELAAEAFGA
DYTFFSVQGTSGAIMTMIMSVAGPGDKIIVPRNVHKSVMSAIVFSGATPIFIHPEIDKELGISHGITPQAVEKALEQHPD
AKGVLVINPTYFGIAGDLKKIVEIAHSYNVPVLVDEAHGVHIHFHEDLPLSAMQAGADMAATSVHKLGGSLTQSSILNVR
EGLVSAKHVQAVLSMLTTTSTSYLLLASLDVARKQLATKGRELIDQAIRLADWTREQINQIPYLYCVGKEILGTEATYDY
DPTKLIISVKELGLTGHDVEQWLRETYNIEVELSDLYNILCIITPGDSEREASLLIEALRRLSEQFSHQAEEGIKPKVLL
PDIPALALTPRDAFYAETEVVPFHESVGRIIAEFVMVYPPGIPIFIPGEIITEENLKYIETNLAAGLPVQGPEDDTLQSL
RVIKEYKPIR

Sequences:

>Translated_490_residues
MSQLETPLFTGLLEHVKKDPIQFHIPGHKKGAGMDPEFRAFIGENALAIDLINISPLDDLHHPKGMIKRAQELAAEAFGA
DYTFFSVQGTSGAIMTMIMSVAGPGDKIIVPRNVHKSVMSAIVFSGATPIFIHPEIDKELGISHGITPQAVEKALEQHPD
AKGVLVINPTYFGIAGDLKKIVEIAHSYNVPVLVDEAHGVHIHFHEDLPLSAMQAGADMAATSVHKLGGSLTQSSILNVR
EGLVSAKHVQAVLSMLTTTSTSYLLLASLDVARKQLATKGRELIDQAIRLADWTREQINQIPYLYCVGKEILGTEATYDY
DPTKLIISVKELGLTGHDVEQWLRETYNIEVELSDLYNILCIITPGDSEREASLLIEALRRLSEQFSHQAEEGIKPKVLL
PDIPALALTPRDAFYAETEVVPFHESVGRIIAEFVMVYPPGIPIFIPGEIITEENLKYIETNLAAGLPVQGPEDDTLQSL
RVIKEYKPIR
>Mature_489_residues
SQLETPLFTGLLEHVKKDPIQFHIPGHKKGAGMDPEFRAFIGENALAIDLINISPLDDLHHPKGMIKRAQELAAEAFGAD
YTFFSVQGTSGAIMTMIMSVAGPGDKIIVPRNVHKSVMSAIVFSGATPIFIHPEIDKELGISHGITPQAVEKALEQHPDA
KGVLVINPTYFGIAGDLKKIVEIAHSYNVPVLVDEAHGVHIHFHEDLPLSAMQAGADMAATSVHKLGGSLTQSSILNVRE
GLVSAKHVQAVLSMLTTTSTSYLLLASLDVARKQLATKGRELIDQAIRLADWTREQINQIPYLYCVGKEILGTEATYDYD
PTKLIISVKELGLTGHDVEQWLRETYNIEVELSDLYNILCIITPGDSEREASLLIEALRRLSEQFSHQAEEGIKPKVLLP
DIPALALTPRDAFYAETEVVPFHESVGRIIAEFVMVYPPGIPIFIPGEIITEENLKYIETNLAAGLPVQGPEDDTLQSLR
VIKEYKPIR

Specific function: Catalyzes the formation of agmatine from arginine [H]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1790573, Length=578, Percent_Identity=25.6055363321799, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1786384, Length=551, Percent_Identity=25.4083484573503, Blast_Score=125, Evalue=7e-30,
Organism=Escherichia coli, GI221142684, Length=387, Percent_Identity=27.906976744186, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI87082193, Length=568, Percent_Identity=22.887323943662, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1786909, Length=586, Percent_Identity=24.061433447099, Blast_Score=102, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 53831; Mature: 53699

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQLETPLFTGLLEHVKKDPIQFHIPGHKKGAGMDPEFRAFIGENALAIDLINISPLDDL
CCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHCCCEEEEEEEECCCCHHH
HHPKGMIKRAQELAAEAFGADYTFFSVQGTSGAIMTMIMSVAGPGDKIIVPRNVHKSVMS
CCCHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHCCCCCEEEECCHHHHHHHH
AIVFSGATPIFIHPEIDKELGISHGITPQAVEKALEQHPDAKGVLVINPTYFGIAGDLKK
HHHHCCCCCEEECCCCCHHCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHH
IVEIAHSYNVPVLVDEAHGVHIHFHEDLPLSAMQAGADMAATSVHKLGGSLTQSSILNVR
HHHHHHCCCCCEEEECCCCEEEEEECCCCHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHH
EGLVSAKHVQAVLSMLTTTSTSYLLLASLDVARKQLATKGRELIDQAIRLADWTREQINQ
HHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IPYLYCVGKEILGTEATYDYDPTKLIISVKELGLTGHDVEQWLRETYNIEVELSDLYNIL
CCEEEEECHHHHCCCCCCCCCCCEEEEEHHHCCCCCHHHHHHHHHHHCEEEEEECCEEEE
CIITPGDSEREASLLIEALRRLSEQFSHQAEEGIKPKVLLPDIPALALTPRDAFYAETEV
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCEEECCCCHHHCCCCE
VPFHESVGRIIAEFVMVYPPGIPIFIPGEIITEENLKYIETNLAAGLPVQGPEDDTLQSL
ECHHHHHHHHHHHHHHHCCCCCCEEECCCEECCCCCHHHHHHHCCCCCCCCCCCHHHHHH
RVIKEYKPIR
HHHHHCCCCC
>Mature Secondary Structure 
SQLETPLFTGLLEHVKKDPIQFHIPGHKKGAGMDPEFRAFIGENALAIDLINISPLDDL
CCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHCCCEEEEEEEECCCCHHH
HHPKGMIKRAQELAAEAFGADYTFFSVQGTSGAIMTMIMSVAGPGDKIIVPRNVHKSVMS
CCCHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHCCCCCEEEECCHHHHHHHH
AIVFSGATPIFIHPEIDKELGISHGITPQAVEKALEQHPDAKGVLVINPTYFGIAGDLKK
HHHHCCCCCEEECCCCCHHCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHH
IVEIAHSYNVPVLVDEAHGVHIHFHEDLPLSAMQAGADMAATSVHKLGGSLTQSSILNVR
HHHHHHCCCCCEEEECCCCEEEEEECCCCHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHH
EGLVSAKHVQAVLSMLTTTSTSYLLLASLDVARKQLATKGRELIDQAIRLADWTREQINQ
HHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IPYLYCVGKEILGTEATYDYDPTKLIISVKELGLTGHDVEQWLRETYNIEVELSDLYNIL
CCEEEEECHHHHCCCCCCCCCCCEEEEEHHHCCCCCHHHHHHHHHHHCEEEEEECCEEEE
CIITPGDSEREASLLIEALRRLSEQFSHQAEEGIKPKVLLPDIPALALTPRDAFYAETEV
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCEEECCCCHHHCCCCE
VPFHESVGRIIAEFVMVYPPGIPIFIPGEIITEENLKYIETNLAAGLPVQGPEDDTLQSL
ECHHHHHHHHHHHHHHHCCCCCCEEECCCEECCCCCHHHHHHHCCCCCCCCCCCHHHHHH
RVIKEYKPIR
HHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]