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The map label for this gene is patA [H]

Identifier: 138894567

GI number: 138894567

Start: 973317

End: 974474

Strand: Reverse

Name: patA [H]

Synonym: GTNG_0897

Alternate gene names: 138894567

Gene position: 974474-973317 (Counterclockwise)

Preceding gene: 138894568

Following gene: 138894553

Centisome position: 27.45

GC content: 54.84

Gene sequence:

>1158_bases
GTGAAACACCTCATTCAGCCACGCGTTCAAGCCATTCAACTATCTGGCATCCGTCAATTTTTCAACCTTGTCTCCGGCCG
GCCAGGGTTAGTTTCCTTGACGATCGGCCAACCGGATTTTCCGACACCCGATCATGTGAAAGTGGCAGCCCAAGAAGCGA
TCGCCGCCGATTTCACAACATATACGGCGAACGCCGGTCTCCTGGAGTTGCGCCAAGCTGCTTGTCAATTTGTCGCTGAT
AAATACGGGCTTCGCTACAGCCCGGATGAAGTGATCGCCACCGTTGGCGCCAGCCAGGCGCTCGATATTACGTTTCGCAC
CATTTTAGAAGAAGGGACGGAGGTGCTTCTTCCCGCGCCGGTCTACCCCGGCTATGAGCCGCTCATCCGCTTGTGCGGGG
CGAAACCGGTGTACATCGATACAAGACAAAACGGCTTTCGTCTGTCGGCCGAGTTGATTAAGCCTTACCTCACCGACAAG
ACACGTTGCCTCGTCCTTCCGTATCCGTCCAATCCGACCGGAACGACGCTGTCAAGTGAAGCGCTGGAAGCCATCGCTGC
ACTGATGAAAGGAAGGCCGATTTGGATCGTGTCTGACGAAATTTACAGCGAGCTCGTCTATTGCGGGCGCCACCGCTCAA
TCGCTGAATGGTTGCCAGAGCAGACTATTGTCATCAACGGTCTAAGCAAATCACACTCGATGACCGGCTGGCGCATCGGA
TTGGTTTTCGCTCCGTCCTTTGTCATCGAACAGATGGTAAAGGTGCATCAATACAGCGTCTCCTGCACGTCGTCGATCAG
CCAAAAAGCAGCGGTTGAGGCGCTTACCGCCGGCAAAAATGACGCCGAGGCAATGCGCGCTGCCTACGCTGAACGGCTTG
AGTACGCTTACAATCGCCTCACGGCCATGGGGCTGCCTGTGGAAAAGCCGGACGGCGCGTTTTATTTGTTTCCGTCGATC
GCTGCGTTTCGTATGCCGTCGTTCGATTTTGCCCTTGATGTCGTTGAAAAAGCCGGCGTCGCCCTTGTTCCCGGAAGCGC
CTTTTCTGAATACGGCGAAGGCTACGTTCGCCTGTCATACGCCTATTCGCTCGATGTGCTCAAAGAAGGGCTCGACCGGC
TCGAACGATACGTTCACGAAAAGAGAAACAGTCTATAA

Upstream 100 bases:

>100_bases
GTCTGCGGAAAACGATCCGAACGGAAAGGGGCTCATTTTTGTTTTTCCGTTTTGCAGGCCCAATGGTACAATAGAGAAAA
AACGGAAAGGTGGACAGCTT

Downstream 100 bases:

>100_bases
AACAAATGTAACGCTGTTTTCCTTTCAGCGCGATATCGTATGCGGTGGCCGCCGATTGGTTTACGCACATATAAAAGGGT
GTCCCACAAAGACAACGGGA

Product: aminotransferase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MKHLIQPRVQAIQLSGIRQFFNLVSGRPGLVSLTIGQPDFPTPDHVKVAAQEAIAADFTTYTANAGLLELRQAACQFVAD
KYGLRYSPDEVIATVGASQALDITFRTILEEGTEVLLPAPVYPGYEPLIRLCGAKPVYIDTRQNGFRLSAELIKPYLTDK
TRCLVLPYPSNPTGTTLSSEALEAIAALMKGRPIWIVSDEIYSELVYCGRHRSIAEWLPEQTIVINGLSKSHSMTGWRIG
LVFAPSFVIEQMVKVHQYSVSCTSSISQKAAVEALTAGKNDAEAMRAAYAERLEYAYNRLTAMGLPVEKPDGAFYLFPSI
AAFRMPSFDFALDVVEKAGVALVPGSAFSEYGEGYVRLSYAYSLDVLKEGLDRLERYVHEKRNSL

Sequences:

>Translated_385_residues
MKHLIQPRVQAIQLSGIRQFFNLVSGRPGLVSLTIGQPDFPTPDHVKVAAQEAIAADFTTYTANAGLLELRQAACQFVAD
KYGLRYSPDEVIATVGASQALDITFRTILEEGTEVLLPAPVYPGYEPLIRLCGAKPVYIDTRQNGFRLSAELIKPYLTDK
TRCLVLPYPSNPTGTTLSSEALEAIAALMKGRPIWIVSDEIYSELVYCGRHRSIAEWLPEQTIVINGLSKSHSMTGWRIG
LVFAPSFVIEQMVKVHQYSVSCTSSISQKAAVEALTAGKNDAEAMRAAYAERLEYAYNRLTAMGLPVEKPDGAFYLFPSI
AAFRMPSFDFALDVVEKAGVALVPGSAFSEYGEGYVRLSYAYSLDVLKEGLDRLERYVHEKRNSL
>Mature_385_residues
MKHLIQPRVQAIQLSGIRQFFNLVSGRPGLVSLTIGQPDFPTPDHVKVAAQEAIAADFTTYTANAGLLELRQAACQFVAD
KYGLRYSPDEVIATVGASQALDITFRTILEEGTEVLLPAPVYPGYEPLIRLCGAKPVYIDTRQNGFRLSAELIKPYLTDK
TRCLVLPYPSNPTGTTLSSEALEAIAALMKGRPIWIVSDEIYSELVYCGRHRSIAEWLPEQTIVINGLSKSHSMTGWRIG
LVFAPSFVIEQMVKVHQYSVSCTSSISQKAAVEALTAGKNDAEAMRAAYAERLEYAYNRLTAMGLPVEKPDGAFYLFPSI
AAFRMPSFDFALDVVEKAGVALVPGSAFSEYGEGYVRLSYAYSLDVLKEGLDRLERYVHEKRNSL

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=420, Percent_Identity=29.0476190476191, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI169881279, Length=420, Percent_Identity=29.0476190476191, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI56713254, Length=323, Percent_Identity=29.4117647058824, Blast_Score=135, Evalue=9e-32,
Organism=Homo sapiens, GI56713256, Length=323, Percent_Identity=29.4117647058824, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI169881281, Length=419, Percent_Identity=26.2529832935561, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI4507369, Length=375, Percent_Identity=24.2666666666667, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI215599424, Length=399, Percent_Identity=24.0601503759398, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI19263340, Length=399, Percent_Identity=24.0601503759398, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI4885351, Length=371, Percent_Identity=25.6064690026954, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1788722, Length=355, Percent_Identity=27.3239436619718, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1786816, Length=355, Percent_Identity=25.9154929577465, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1788627, Length=368, Percent_Identity=27.1739130434783, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI1787710, Length=357, Percent_Identity=28.0112044817927, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1788332, Length=171, Percent_Identity=28.0701754385965, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI71994476, Length=272, Percent_Identity=29.0441176470588, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71994472, Length=272, Percent_Identity=29.0441176470588, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17567663, Length=371, Percent_Identity=25.6064690026954, Blast_Score=101, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17567369, Length=294, Percent_Identity=26.8707482993197, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71981209, Length=370, Percent_Identity=23.7837837837838, Blast_Score=76, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6322401, Length=387, Percent_Identity=22.9974160206718, Blast_Score=106, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6320317, Length=355, Percent_Identity=24.7887323943662, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6323118, Length=377, Percent_Identity=24.4031830238727, Blast_Score=77, Evalue=5e-15,
Organism=Drosophila melanogaster, GI28573069, Length=388, Percent_Identity=24.4845360824742, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24646114, Length=388, Percent_Identity=24.4845360824742, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI28573067, Length=388, Percent_Identity=24.4845360824742, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI28573065, Length=388, Percent_Identity=24.4845360824742, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI18859735, Length=382, Percent_Identity=23.8219895287958, Blast_Score=82, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 42450; Mature: 42450

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHLIQPRVQAIQLSGIRQFFNLVSGRPGLVSLTIGQPDFPTPDHVKVAAQEAIAADFTT
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHE
YTANAGLLELRQAACQFVADKYGLRYSPDEVIATVGASQALDITFRTILEEGTEVLLPAP
EECCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCEEEECCC
VYPGYEPLIRLCGAKPVYIDTRQNGFRLSAELIKPYLTDKTRCLVLPYPSNPTGTTLSSE
CCCCHHHHHHHHCCCCEEEECCCCCCEEEHHHHHHHHCCCCEEEEEECCCCCCCCCCCHH
ALEAIAALMKGRPIWIVSDEIYSELVYCGRHRSIAEWLPEQTIVINGLSKSHSMTGWRIG
HHHHHHHHHCCCCEEEECHHHHHHHHHHCCCCCHHHHCCCCEEEEECCCCCCCCCCEEEE
LVFAPSFVIEQMVKVHQYSVSCTSSISQKAAVEALTAGKNDAEAMRAAYAERLEYAYNRL
EEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
TAMGLPVEKPDGAFYLFPSIAAFRMPSFDFALDVVEKAGVALVPGSAFSEYGEGYVRLSY
HHCCCCCCCCCCCEEECCCHHHHCCCCHHHHHHHHHHCCEEEECCCHHHHHCCCEEEEEE
AYSLDVLKEGLDRLERYVHEKRNSL
EHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKHLIQPRVQAIQLSGIRQFFNLVSGRPGLVSLTIGQPDFPTPDHVKVAAQEAIAADFTT
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHE
YTANAGLLELRQAACQFVADKYGLRYSPDEVIATVGASQALDITFRTILEEGTEVLLPAP
EECCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCEEEECCC
VYPGYEPLIRLCGAKPVYIDTRQNGFRLSAELIKPYLTDKTRCLVLPYPSNPTGTTLSSE
CCCCHHHHHHHHCCCCEEEECCCCCCEEEHHHHHHHHCCCCEEEEEECCCCCCCCCCCHH
ALEAIAALMKGRPIWIVSDEIYSELVYCGRHRSIAEWLPEQTIVINGLSKSHSMTGWRIG
HHHHHHHHHCCCCEEEECHHHHHHHHHHCCCCCHHHHCCCCEEEEECCCCCCCCCCEEEE
LVFAPSFVIEQMVKVHQYSVSCTSSISQKAAVEALTAGKNDAEAMRAAYAERLEYAYNRL
EEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
TAMGLPVEKPDGAFYLFPSIAAFRMPSFDFALDVVEKAGVALVPGSAFSEYGEGYVRLSY
HHCCCCCCCCCCCEEECCCHHHHCCCCHHHHHHHHHHCCEEEECCCHHHHHCCCEEEEEE
AYSLDVLKEGLDRLERYVHEKRNSL
EHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 2104615 [H]