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The map label for this gene is cysS

Identifier: 138893764

GI number: 138893764

Start: 103993

End: 105396

Strand: Direct

Name: cysS

Synonym: GTNG_0085

Alternate gene names: 138893764

Gene position: 103993-105396 (Clockwise)

Preceding gene: 138893763

Following gene: 138893765

Centisome position: 2.93

GC content: 49.5

Gene sequence:

>1404_bases
ATGAGCAGTATCCGACTTTATAATACGTTGACGCGAAAAAAGGAAACGTTTGAGCCGCTCGAACCGAACAAAGTGAAAAT
GTATGTATGTGGCCCGACGGTCTATAATTATATTCATATCGGCAATGCTCGCGCCGCTATCGTCTTTGATACGATCCGCC
GTTATTTAGAGTTCCGCGGTTATGATGTGACGTATGTATCCAACTTTACTGATGTCGACGACAAGCTAATCAGGGCGGCC
CGCGAGCTTGGTGAGAGCGTGCCGGCGATCGCCGAGCGGTTTATTGAGGCGTATTTTGAGGACATTGAGGCGCTCGGCTG
CAAAAAAGCAGATATCCATCCGCGCGTGACGGAAAATATCGAAACGATTATCGAATTCATTCAAGCGCTCATTGACAAAG
GCTATGCGTACGAAGTCGATGGTGACGTATACTATCGGACGCGCAAGTTTGATGGCTACGGCAAATTGTCGCATCAGTCG
ATCGATGAGCTACAAGCGGGGGCGCGCATCGAAGTTGGGGAAAAGAAAGATGATCCACTCGATTTTGCTCTTTGGAAAGC
AGCGAAAGAAGGAGAGATTTCTTGGGACAGCCCATGGGGGAAAGGGCGGCCCGGCTGGCATATCGAATGTTCAGCGATGG
CGCGCAAATATTTAGGAGATACGATCGACATTCATGCTGGCGGCCAAGACTTAACGTTTCCACACCATGAAAACGAAATT
GCCCAATCGGAAGCACTGACCGGCAAACCGTTTGCGAAATATTGGCTGCACAATGGGTATTTAAATATTAACAATGAAAA
AATGTCCAAGTCGCTTGGCAACTTTGTACTTGTTCACGATATCATCCGGCAGATTGACCCACAAGTGTTGCGTTTCTTTA
TGCTGTCGGTGCACTATCGCCACCCGATCAACTATAGCGAGGAGCTGCTTGAGAGCGCTCGGCGTGGTCTCGAACGCTTG
AGGACAGCATACGGTAATTTGCAGCACCGGCTTGGGGCGAGCACGAACTTAACCGATAACGACGGCGAGTGGCTTTCGCG
CCTCGCGGATATCCGCGCCTCGTTCATTCGTGAAATGGACGATGATTTCAACACAGCAAACGGCATTGCGGTCTTGTTCG
AGCTCGCCAAACAAGCGAACTTGTATTTGCAGGAGAAAACGACATCCGAGAATGTCATTCACGCGTTTTTGCGCGAATTT
GAGCAGCTGATGGATGTACTCGGCCTTACTTTGAAACAAGAGGAGTTGCTTGACGAAGAAATTGAGGCGCTGATCCGCCA
GCGCAATGAAGCGCGGAAAAATCGTGACTTTGCCTTAGCCGACCGCATCCGCGACGAGTTGAAAGCAAAAAATATCATTT
TGGAAGATACGCCGCAAGGGACGAGATGGAAACGGGGATCGTAA

Upstream 100 bases:

>100_bases
CCGGACCCGATCGCGGACCGATTCCGGGAGCTTGAGGCTGAAATCGCCCGGCTGCAAAGCGAGCTTGAGGCATTGAAACA
ACATGAAAGGAAGAGCGAAT

Downstream 100 bases:

>100_bases
ACGATGGCACAGTTTGAAATCATCCATGATGTGAAACAATTAAATGGCTTGGCGCTCGCCTATATTGGCGACGCCGTTTA
CGAGGTGTATGTGCGCCGCC

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS

Number of amino acids: Translated: 467; Mature: 466

Protein sequence:

>467_residues
MSSIRLYNTLTRKKETFEPLEPNKVKMYVCGPTVYNYIHIGNARAAIVFDTIRRYLEFRGYDVTYVSNFTDVDDKLIRAA
RELGESVPAIAERFIEAYFEDIEALGCKKADIHPRVTENIETIIEFIQALIDKGYAYEVDGDVYYRTRKFDGYGKLSHQS
IDELQAGARIEVGEKKDDPLDFALWKAAKEGEISWDSPWGKGRPGWHIECSAMARKYLGDTIDIHAGGQDLTFPHHENEI
AQSEALTGKPFAKYWLHNGYLNINNEKMSKSLGNFVLVHDIIRQIDPQVLRFFMLSVHYRHPINYSEELLESARRGLERL
RTAYGNLQHRLGASTNLTDNDGEWLSRLADIRASFIREMDDDFNTANGIAVLFELAKQANLYLQEKTTSENVIHAFLREF
EQLMDVLGLTLKQEELLDEEIEALIRQRNEARKNRDFALADRIRDELKAKNIILEDTPQGTRWKRGS

Sequences:

>Translated_467_residues
MSSIRLYNTLTRKKETFEPLEPNKVKMYVCGPTVYNYIHIGNARAAIVFDTIRRYLEFRGYDVTYVSNFTDVDDKLIRAA
RELGESVPAIAERFIEAYFEDIEALGCKKADIHPRVTENIETIIEFIQALIDKGYAYEVDGDVYYRTRKFDGYGKLSHQS
IDELQAGARIEVGEKKDDPLDFALWKAAKEGEISWDSPWGKGRPGWHIECSAMARKYLGDTIDIHAGGQDLTFPHHENEI
AQSEALTGKPFAKYWLHNGYLNINNEKMSKSLGNFVLVHDIIRQIDPQVLRFFMLSVHYRHPINYSEELLESARRGLERL
RTAYGNLQHRLGASTNLTDNDGEWLSRLADIRASFIREMDDDFNTANGIAVLFELAKQANLYLQEKTTSENVIHAFLREF
EQLMDVLGLTLKQEELLDEEIEALIRQRNEARKNRDFALADRIRDELKAKNIILEDTPQGTRWKRGS
>Mature_466_residues
SSIRLYNTLTRKKETFEPLEPNKVKMYVCGPTVYNYIHIGNARAAIVFDTIRRYLEFRGYDVTYVSNFTDVDDKLIRAAR
ELGESVPAIAERFIEAYFEDIEALGCKKADIHPRVTENIETIIEFIQALIDKGYAYEVDGDVYYRTRKFDGYGKLSHQSI
DELQAGARIEVGEKKDDPLDFALWKAAKEGEISWDSPWGKGRPGWHIECSAMARKYLGDTIDIHAGGQDLTFPHHENEIA
QSEALTGKPFAKYWLHNGYLNINNEKMSKSLGNFVLVHDIIRQIDPQVLRFFMLSVHYRHPINYSEELLESARRGLERLR
TAYGNLQHRLGASTNLTDNDGEWLSRLADIRASFIREMDDDFNTANGIAVLFELAKQANLYLQEKTTSENVIHAFLREFE
QLMDVLGLTLKQEELLDEEIEALIRQRNEARKNRDFALADRIRDELKAKNIILEDTPQGTRWKRGS

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI13375695, Length=489, Percent_Identity=35.5828220858896, Blast_Score=270, Evalue=2e-72,
Organism=Homo sapiens, GI21269877, Length=316, Percent_Identity=37.9746835443038, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI62240992, Length=316, Percent_Identity=37.9746835443038, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI10835051, Length=316, Percent_Identity=37.9746835443038, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI303304987, Length=316, Percent_Identity=37.9746835443038, Blast_Score=211, Evalue=2e-54,
Organism=Escherichia coli, GI1786737, Length=474, Percent_Identity=47.2573839662447, Blast_Score=416, Evalue=1e-117,
Organism=Caenorhabditis elegans, GI17509797, Length=244, Percent_Identity=37.7049180327869, Blast_Score=172, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI17509795, Length=244, Percent_Identity=37.7049180327869, Blast_Score=172, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6324082, Length=332, Percent_Identity=35.8433734939759, Blast_Score=200, Evalue=3e-52,
Organism=Drosophila melanogaster, GI19922218, Length=510, Percent_Identity=32.5490196078431, Blast_Score=240, Evalue=2e-63,
Organism=Drosophila melanogaster, GI19922364, Length=328, Percent_Identity=35.0609756097561, Blast_Score=192, Evalue=4e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SYC_GEOTN (A4IJG8)

Other databases:

- EMBL:   CP000557
- RefSeq:   YP_001124217.1
- ProteinModelPortal:   A4IJG8
- SMR:   A4IJG8
- STRING:   A4IJG8
- GeneID:   4965211
- GenomeReviews:   CP000557_GR
- KEGG:   gtn:GTNG_0085
- NMPDR:   fig|420246.5.peg.85
- eggNOG:   COG0215
- HOGENOM:   HBG327651
- OMA:   DFDALNM
- PhylomeDB:   A4IJG8
- ProtClustDB:   PRK00260
- BioCyc:   GTHE420246:GTNG_0085-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00041_B
- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR10890
- PRINTS:   PR00983
- SMART:   SM00840
- TIGRFAMs:   TIGR00435

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.16

Molecular weight: Translated: 53868; Mature: 53737

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 270-270

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSIRLYNTLTRKKETFEPLEPNKVKMYVCGPTVYNYIHIGNARAAIVFDTIRRYLEFRG
CCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCHHEEEEEECCCCHHHHHHHHHHHHHHCC
YDVTYVSNFTDVDDKLIRAARELGESVPAIAERFIEAYFEDIEALGCKKADIHPRVTENI
CCEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
ETIIEFIQALIDKGYAYEVDGDVYYRTRKFDGYGKLSHQSIDELQAGARIEVGEKKDDPL
HHHHHHHHHHHCCCCEEEECCCEEEEEEECCCCCCCCHHHHHHHHCCCEEECCCCCCCCH
DFALWKAAKEGEISWDSPWGKGRPGWHIECSAMARKYLGDTIDIHAGGQDLTFPHHENEI
HHHHHHCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCEEEEECCCCCCCCCCCCCHH
AQSEALTGKPFAKYWLHNGYLNINNEKMSKSLGNFVLVHDIIRQIDPQVLRFFMLSVHYR
HHHHCCCCCHHHHHHHCCCEEEECHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHHC
HPINYSEELLESARRGLERLRTAYGNLQHRLGASTNLTDNDGEWLSRLADIRASFIREMD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
DDFNTANGIAVLFELAKQANLYLQEKTTSENVIHAFLREFEQLMDVLGLTLKQEELLDEE
CCCCCCCHHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
IEALIRQRNEARKNRDFALADRIRDELKAKNIILEDTPQGTRWKRGS
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEECCCCCCCCCCCC
>Mature Secondary Structure 
SSIRLYNTLTRKKETFEPLEPNKVKMYVCGPTVYNYIHIGNARAAIVFDTIRRYLEFRG
CCCHHHHHHHHHHHHCCCCCCCCEEEEEECCHHEEEEEECCCCHHHHHHHHHHHHHHCC
YDVTYVSNFTDVDDKLIRAARELGESVPAIAERFIEAYFEDIEALGCKKADIHPRVTENI
CCEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
ETIIEFIQALIDKGYAYEVDGDVYYRTRKFDGYGKLSHQSIDELQAGARIEVGEKKDDPL
HHHHHHHHHHHCCCCEEEECCCEEEEEEECCCCCCCCHHHHHHHHCCCEEECCCCCCCCH
DFALWKAAKEGEISWDSPWGKGRPGWHIECSAMARKYLGDTIDIHAGGQDLTFPHHENEI
HHHHHHCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCEEEEECCCCCCCCCCCCCHH
AQSEALTGKPFAKYWLHNGYLNINNEKMSKSLGNFVLVHDIIRQIDPQVLRFFMLSVHYR
HHHHCCCCCHHHHHHHCCCEEEECHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHHC
HPINYSEELLESARRGLERLRTAYGNLQHRLGASTNLTDNDGEWLSRLADIRASFIREMD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
DDFNTANGIAVLFELAKQANLYLQEKTTSENVIHAFLREFEQLMDVLGLTLKQEELLDEE
CCCCCCCHHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
IEALIRQRNEARKNRDFALADRIRDELKAKNIILEDTPQGTRWKRGS
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA