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The map label for this gene is udk [H]

Identifier: 13508300

GI number: 13508300

Start: 681847

End: 682488

Strand: Direct

Name: udk [H]

Synonym: MPN561

Alternate gene names: 13508300

Gene position: 681847-682488 (Clockwise)

Preceding gene: 13508298

Following gene: 13508317

Centisome position: 83.52

GC content: 41.59

Gene sequence:

>642_bases
ATGGATAGTAAAAAAGGAATTTTAGTGGCAATTGGTGGCGGGAGTTGTTCTGGTAAAACTACGATCGCTGACATGATTTA
CCAACTTTTGCGTAAAAAGCTTAAAGTTGCTATTCTGCCCCAGGACAACTATTACAAACCATACAAGAACAAATCAATGG
CGCAACGCAAAGCGATTAACTTCGATCACCCCGATGCCTTTGATTGAAAGCTGTTGTGAAGTCACCTCGATAACTTACTA
ATGGGTAAAACAGTGGCTGTGCCAATGTATGACTATGTTAATTACACCCGTAAAAAGGAAACCATAGAAATAGGTCCTTT
AAATGTAGTCATCTTGGAAGGTTTAATGCCGTGGTTTGATGAACGGATTGCTAAATTGTGTAAGCTCAAGATCTTTGTGG
AAGCGACTGGAGAGGAACGCTTAATTCGCCGGATTGAACGGGACTGGGAACGCGGTCGTGATGTCGCTTCTATCATTAAA
CAATGACGCGAAGCAGTTAGTCCAATGTACGAAATCTTTGTCGAAAAGATGAAACAGAAGGCAGATTTAATTATTCCCTG
GAGTGAAAGACACGAAGTGAGTACTAATGTGCTCGACTTTGCAATTGAACACCTCTTTCGCAAACACGTGGATCCCAACT
AG

Upstream 100 bases:

>100_bases
TCTAATTGGTTATGCCCATCGGTTTTGACAAGCTGTTTTTTTGACATGTAAATTCGATTAATTTTAAATAATTAACAATT
GCTTTAATTGCGTTACTTCC

Downstream 100 bases:

>100_bases
ATTTGGAAGGAATAAAGTGGTTTAAAGGTTTTAGGTAAACTACGCTTGTGCTGGGAGCTTTGGCGCAAGTGGTCAACCCG
TTGTTGTTTCGTGGCACTTA

Product: uridine kinase

Products: NA

Alternate protein names: Cytidine monophosphokinase; Uridine monophosphokinase [H]

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MDSKKGILVAIGGGSCSGKTTIADMIYQLLRKKLKVAILPQDNYYKPYKNKSMAQRKAINFDHPDAFDWKLLWSHLDNLL
MGKTVAVPMYDYVNYTRKKETIEIGPLNVVILEGLMPWFDERIAKLCKLKIFVEATGEERLIRRIERDWERGRDVASIIK
QWREAVSPMYEIFVEKMKQKADLIIPWSERHEVSTNVLDFAIEHLFRKHVDPN

Sequences:

>Translated_213_residues
MDSKKGILVAIGGGSCSGKTTIADMIYQLLRKKLKVAILPQDNYYKPYKNKSMAQRKAINFDHPDAFD*KLL*SHLDNLL
MGKTVAVPMYDYVNYTRKKETIEIGPLNVVILEGLMPWFDERIAKLCKLKIFVEATGEERLIRRIERDWERGRDVASIIK
Q*REAVSPMYEIFVEKMKQKADLIIPWSERHEVSTNVLDFAIEHLFRKHVDPN
>Mature_213_residues
MDSKKGILVAIGGGSCSGKTTIADMIYQLLRKKLKVAILPQDNYYKPYKNKSMAQRKAINFDHPDAFD*KLL*SHLDNLL
MGKTVAVPMYDYVNYTRKKETIEIGPLNVVILEGLMPWFDERIAKLCKLKIFVEATGEERLIRRIERDWERGRDVASIIK
Q*REAVSPMYEIFVEKMKQKADLIIPWSERHEVSTNVLDFAIEHLFRKHVDPN

Specific function: Pyrimidine salvage pathway. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uridine kinase family [H]

Homologues:

Organism=Homo sapiens, GI13899253, Length=210, Percent_Identity=37.6190476190476, Blast_Score=141, Evalue=3e-34,
Organism=Homo sapiens, GI18699734, Length=208, Percent_Identity=36.5384615384615, Blast_Score=140, Evalue=5e-34,
Organism=Homo sapiens, GI301129207, Length=206, Percent_Identity=37.8640776699029, Blast_Score=138, Evalue=3e-33,
Organism=Homo sapiens, GI57863312, Length=206, Percent_Identity=37.8640776699029, Blast_Score=138, Evalue=3e-33,
Organism=Homo sapiens, GI209863022, Length=149, Percent_Identity=38.9261744966443, Blast_Score=111, Evalue=6e-25,
Organism=Escherichia coli, GI87082034, Length=208, Percent_Identity=37.5, Blast_Score=146, Evalue=8e-37,
Organism=Caenorhabditis elegans, GI71981181, Length=216, Percent_Identity=34.2592592592593, Blast_Score=117, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17539894, Length=199, Percent_Identity=36.6834170854271, Blast_Score=114, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17539892, Length=199, Percent_Identity=36.6834170854271, Blast_Score=114, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6324339, Length=184, Percent_Identity=32.0652173913043, Blast_Score=80, Evalue=2e-16,
Organism=Drosophila melanogaster, GI221458995, Length=212, Percent_Identity=34.9056603773585, Blast_Score=120, Evalue=6e-28,
Organism=Drosophila melanogaster, GI24649624, Length=212, Percent_Identity=34.9056603773585, Blast_Score=120, Evalue=8e-28,
Organism=Drosophila melanogaster, GI28573516, Length=206, Percent_Identity=36.4077669902913, Blast_Score=114, Evalue=5e-26,
Organism=Drosophila melanogaster, GI28573514, Length=206, Percent_Identity=36.4077669902913, Blast_Score=114, Evalue=5e-26,
Organism=Drosophila melanogaster, GI28573512, Length=206, Percent_Identity=36.4077669902913, Blast_Score=114, Evalue=5e-26,
Organism=Drosophila melanogaster, GI45550449, Length=206, Percent_Identity=36.4077669902913, Blast_Score=114, Evalue=6e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006083
- InterPro:   IPR000764 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.48 [H]

Molecular weight: Translated: 24300; Mature: 24300

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSKKGILVAIGGGSCSGKTTIADMIYQLLRKKLKVAILPQDNYYKPYKNKSMAQRKAIN
CCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCHHHHHHHCCC
FDHPDAFDKLLSHLDNLLMGKTVAVPMYDYVNYTRKKETIEIGPLNVVILEGLMPWFDER
CCCCHHHHHHHHHHHHHHHCCHHEEHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHH
IAKLCKLKIFVEATGEERLIRRIERDWERGRDVASIIKQREAVSPMYEIFVEKMKQKADL
HHHHHHHHHEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCE
IIPWSERHEVSTNVLDFAIEHLFRKHVDPN
EECCCCCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDSKKGILVAIGGGSCSGKTTIADMIYQLLRKKLKVAILPQDNYYKPYKNKSMAQRKAIN
CCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCHHHHHHHCCC
FDHPDAFDKLLSHLDNLLMGKTVAVPMYDYVNYTRKKETIEIGPLNVVILEGLMPWFDER
CCCCHHHHHHHHHHHHHHHCCHHEEHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHH
IAKLCKLKIFVEATGEERLIRRIERDWERGRDVASIIKQREAVSPMYEIFVEKMKQKADL
HHHHHHHHHEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCE
IIPWSERHEVSTNVLDFAIEHLFRKHVDPN
EECCCCCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]