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The map label for this gene is ruvA

Identifier: 13508274

GI number: 13508274

Start: 656922

End: 657542

Strand: Direct

Name: ruvA

Synonym: MPN535

Alternate gene names: 13508274

Gene position: 656922-657542 (Clockwise)

Preceding gene: 13508273

Following gene: 13508275

Centisome position: 80.47

GC content: 37.84

Gene sequence:

>621_bases
ATGATTGCTTCAATTTTTGGAAAAATTACCTTTGTTGGTAAGCGAAAAATTATTGTTGAAGCCAATTGTATTTCCTATTG
GTTTAATGTGAAAGAAAACCATAGCTTCGAAAAGAACTTGGAAAAACCGCGCCAGGTCTTCTGTCAGATCATTAAAAGAA
TGGTTACGAACCAGATCTTGGAAGAGGGCTTTGCCTTCAATACCTTAGAGGAAAAGGAATGGTTTTCGAAGTTCATCGAA
CTCAATGGCATTGGTAGTAAAACTGCTTTAAACTTGCTCAATAACAACCTCGAGGAAATGCGTGATTATATTAAAAACAG
TAACTACCATGCCTTGACTAAGTTAACTGGTTCTAACAGTAAGGTAGCTCGCGCATTGCTGGCACTGGAACTGTATGACC
GAGACGATGGTGGTAAACGGATTAAACCCAACACTGCCATGGCCAATGACTATGATGAGATGTTTGACACCTTAAAGTCG
TTGGGCTATAAACCCCAAGATATCCAAAACGCTTTGAGCAAAATTGAAATTAAACCTAACTTTGATGTAAGTGAAGTGAT
TGCTGAAGTGATTAAGTTAATGTCTTTCCAGAACAATGAAGTTACAAATAAAACCGCCTAA

Upstream 100 bases:

>100_bases
CCATGGAGACTTACCGTACCACTAATATTAAGTTTAGAGTACCCAAGTCTTACTATGATGCCAAACAGCAAATTAGAAAG
GTAATTAAAAACTAAGGACT

Downstream 100 bases:

>100_bases
CAATTTCGCTGAGTTTGTCGGTAAACAAGAAATTATTAACCAAATTCAACTCAGCATTAAAGCGTCCCGTATCAATAAGG
CGCAGTTGGACCACATTCTT

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MIASIFGKITFVGKRKIIVEANCISYWFNVKENHSFEKNLEKPRQVFCQIIKRMVTNQILEEGFAFNTLEEKEWFSKFIE
LNGIGSKTALNLLNNNLEEMRDYIKNSNYHALTKLTGSNSKVARALLALELYDRDDGGKRIKPNTAMANDYDEMFDTLKS
LGYKPQDIQNALSKIEIKPNFDVSEVIAEVIKLMSFQNNEVTNKTA

Sequences:

>Translated_206_residues
MIASIFGKITFVGKRKIIVEANCISYWFNVKENHSFEKNLEKPRQVFCQIIKRMVTNQILEEGFAFNTLEEKEWFSKFIE
LNGIGSKTALNLLNNNLEEMRDYIKNSNYHALTKLTGSNSKVARALLALELYDRDDGGKRIKPNTAMANDYDEMFDTLKS
LGYKPQDIQNALSKIEIKPNFDVSEVIAEVIKLMSFQNNEVTNKTA
>Mature_206_residues
MIASIFGKITFVGKRKIIVEANCISYWFNVKENHSFEKNLEKPRQVFCQIIKRMVTNQILEEGFAFNTLEEKEWFSKFIE
LNGIGSKTALNLLNNNLEEMRDYIKNSNYHALTKLTGSNSKVARALLALELYDRDDGGKRIKPNTAMANDYDEMFDTLKS
LGYKPQDIQNALSKIEIKPNFDVSEVIAEVIKLMSFQNNEVTNKTA

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_MYCPN (P75243)

Other databases:

- EMBL:   U00089
- PIR:   S73633
- RefSeq:   NP_110224.1
- ProteinModelPortal:   P75243
- GeneID:   877275
- GenomeReviews:   U00089_GR
- KEGG:   mpn:MPN535
- HOGENOM:   HBG130141
- OMA:   FKERLLF
- ProtClustDB:   PRK00116
- BioCyc:   MPNE272634:MPN535-MONOMER
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR000085
- InterPro:   IPR010994
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF47781 RuvA_2_like

EC number: =3.6.4.12

Molecular weight: Translated: 23660; Mature: 23660

Theoretical pI: Translated: 8.18; Mature: 8.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIASIFGKITFVGKRKIIVEANCISYWFNVKENHSFEKNLEKPRQVFCQIIKRMVTNQIL
CCHHHHHHEEEEECEEEEEEEHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EEGFAFNTLEEKEWFSKFIELNGIGSKTALNLLNNNLEEMRDYIKNSNYHALTKLTGSNS
HCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHCCCCEEEEEECCCCH
KVARALLALELYDRDDGGKRIKPNTAMANDYDEMFDTLKSLGYKPQDIQNALSKIEIKPN
HHHHHHHHHHHHCCCCCCCEECCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHEECCCC
FDVSEVIAEVIKLMSFQNNEVTNKTA
CCHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MIASIFGKITFVGKRKIIVEANCISYWFNVKENHSFEKNLEKPRQVFCQIIKRMVTNQIL
CCHHHHHHEEEEECEEEEEEEHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EEGFAFNTLEEKEWFSKFIELNGIGSKTALNLLNNNLEEMRDYIKNSNYHALTKLTGSNS
HCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHCCCCEEEEEECCCCH
KVARALLALELYDRDDGGKRIKPNTAMANDYDEMFDTLKSLGYKPQDIQNALSKIEIKPN
HHHHHHHHHHHHCCCCCCCEECCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHEECCCC
FDVSEVIAEVIKLMSFQNNEVTNKTA
CCHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8948633