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The map label for this gene is 13508019

Identifier: 13508019

GI number: 13508019

Start: 331360

End: 333069

Strand: Direct

Name: 13508019

Synonym: MPN280

Alternate gene names: NA

Gene position: 331360-333069 (Clockwise)

Preceding gene: 13508018

Following gene: 13508020

Centisome position: 40.59

GC content: 43.27

Gene sequence:

>1710_bases
ATGATTAAGGATTTTGATCCTAGTGAGTTTGTCGGTAAAACTCCTACCAAGATTTTTGCCTTTGGTGGTATCCAAGAAGT
TGGAAAAAACATGTATGGAATCGAGTACGATGATGAGATTATCATCATCGACTGCGGTATTAAGTTTGCTAGTGATGATC
TACTAGGGATTGATGGTATTATCCCGAGCTTCGAATACCTCATTGAAAACCAAGCTAAGGTTAAAGCACTGTTTATCACC
CACGGCCATGAAGACCACATTGGTGGGGTGCCTTACTTGTTAAAACAAGTCGATGTACCGGTGATTTACGCACCCCGGAT
TGCCGCTTCTTTGATCTTAAAGAAGGTCAACGAACACAAGGATGCTAAGCTCAATAAAGTGGTCGTATATGATGACTTTA
GCAACTTTGAAACCAAGCACTTCAAGATTGACTTTTACCGCGTCAACCACTCGATTCCTGACGCCTTTGGTGTCTGTGTT
CAAACTCCCAACGGTAACATTGTTGAGAGTGGTGACTTTCGCTTTGACTTTGCCGCTGGCGGGGAAATGCTCGATGTGCA
TAAGGTCGTGAAGATTGCCGAGCGCAATGTCCATGTCTTTATGTGTGAGACTACTAACGCCGAAATCCCGGGGTTCTCCC
AGAGCGAAAAGTTAATTTACCGCAACATCAACAAGATTATTAAAGAAGCACGTGGTCGGGTCATTCTCACTACCTTTGCT
TCCAACATTACCCGGATTAACGAAATTATTGAGATTGCTGTTAACAATAAACGGAAGGTCTGCTTGTTGGGTAAGTCGAT
GGATGTGAACGTCAACATCTCGCGTAAGATTGGCTTAATGGACATTGACAGCAATGACATTGTGGAAGTCCGTGACATTA
AGAATTACCCCGACCGCAGTATCTTAATCTTGTGTACGGGTTCCCAAGGTGAAGACTCAGCAGCCTTAAACACAATGGCA
CGGGGTAAACATAACTGGGTTAGCTTAAAGTCCACTGACACCATTATTATGTCCTCCAACCCGATTCCGGGGAACTATGC
AGCGGTGGAAAATCTCTTGAATGAGCTTTCGAAGTACGGGGTGACCATCTTTGAAAACTCACCGAACATGAAGCTACACG
CCTCTGGTCACGCTACCCAGCAAGAGTTGCAGTTAATGTTAAACCTCGTGTTTCCAAGGTACTTAATTCCGATTCACGGG
GAGTACAAGATGATGCGCACCATCAAAAACATAGCGCAAGAATGTGGCATTAACGGTGATGATGTTGGTTTGCTAGCTAA
CGGTCAGGTGATGTACCTAATTGATGGCAAGCTGTATTACTCAGGGGAAGTGATTAATGCTGACCCGATTTACATTGAAA
GCCGCAATTCTTCTCCAGACTTAGCGCGGGTAATTAAACAACGCCAAATCTTGAGTCGGGAGGGAATGTTTGCTGTGATT
GTAGTCTTTGACAAAAACAATAACATTTTAGGGATGCCTACTCTGATTACTCGGGGTTGTTTCTTTGCTCTAGATTCCAG
TCCGTTAATGACTAAGATTACCCACTCAATTAAACGCGGTTTGGAAAACGTTATTCAAAACAAGCGTTTTAATACCCGTG
AACAGATGATCAAGGAATTGAAACGAGTATGTAAGGAAACGGTGTCTTACTTCATTTGGAAGAACAAGAGTCGTAACCCG
TTGATTTCAACCGTATTGTCTTGAGTTTAA

Upstream 100 bases:

>100_bases
TTTGCTCAAAGATGAAGATTAACTTATTTATAATTGATTACTGTTTAATTACTGATACCTTGTAAAGGTATTAACTAATT
ATTTTGATCTTTTATAAGTA

Downstream 100 bases:

>100_bases
ACCTTAGTTTTAACTAATTCTCAATTGGACCCAATTATTGGAAATTAACACCTTTATAAGGCTGTTTTTGCCAGTAGTTG
GGTTTTCTTTTGTTTGCTCT

Product: single stranded RNA(DNA) processing enzyme

Products: NA

Alternate protein names: RNase J [H]

Number of amino acids: Translated: 569; Mature: 569

Protein sequence:

>569_residues
MIKDFDPSEFVGKTPTKIFAFGGIQEVGKNMYGIEYDDEIIIIDCGIKFASDDLLGIDGIIPSFEYLIENQAKVKALFIT
HGHEDHIGGVPYLLKQVDVPVIYAPRIAASLILKKVNEHKDAKLNKVVVYDDFSNFETKHFKIDFYRVNHSIPDAFGVCV
QTPNGNIVESGDFRFDFAAGGEMLDVHKVVKIAERNVHVFMCETTNAEIPGFSQSEKLIYRNINKIIKEARGRVILTTFA
SNITRINEIIEIAVNNKRKVCLLGKSMDVNVNISRKIGLMDIDSNDIVEVRDIKNYPDRSILILCTGSQGEDSAALNTMA
RGKHNWVSLKSTDTIIMSSNPIPGNYAAVENLLNELSKYGVTIFENSPNMKLHASGHATQQELQLMLNLVFPRYLIPIHG
EYKMMRTIKNIAQECGINGDDVGLLANGQVMYLIDGKLYYSGEVINADPIYIESRNSSPDLARVIKQRQILSREGMFAVI
VVFDKNNNILGMPTLITRGCFFALDSSPLMTKITHSIKRGLENVIQNKRFNTREQMIKELKRVCKETVSYFIWKNKSRNP
LISTVLSWV

Sequences:

>Translated_569_residues
MIKDFDPSEFVGKTPTKIFAFGGIQEVGKNMYGIEYDDEIIIIDCGIKFASDDLLGIDGIIPSFEYLIENQAKVKALFIT
HGHEDHIGGVPYLLKQVDVPVIYAPRIAASLILKKVNEHKDAKLNKVVVYDDFSNFETKHFKIDFYRVNHSIPDAFGVCV
QTPNGNIVESGDFRFDFAAGGEMLDVHKVVKIAERNVHVFMCETTNAEIPGFSQSEKLIYRNINKIIKEARGRVILTTFA
SNITRINEIIEIAVNNKRKVCLLGKSMDVNVNISRKIGLMDIDSNDIVEVRDIKNYPDRSILILCTGSQGEDSAALNTMA
RGKHNWVSLKSTDTIIMSSNPIPGNYAAVENLLNELSKYGVTIFENSPNMKLHASGHATQQELQLMLNLVFPRYLIPIHG
EYKMMRTIKNIAQECGINGDDVGLLANGQVMYLIDGKLYYSGEVINADPIYIESRNSSPDLARVIKQRQILSREGMFAVI
VVFDKNNNILGMPTLITRGCFFALDSSPLMTKITHSIKRGLENVIQNKRFNTREQMIKELKRVCKETVSYFIWKNKSRNP
LISTVLS*V
>Mature_569_residues
MIKDFDPSEFVGKTPTKIFAFGGIQEVGKNMYGIEYDDEIIIIDCGIKFASDDLLGIDGIIPSFEYLIENQAKVKALFIT
HGHEDHIGGVPYLLKQVDVPVIYAPRIAASLILKKVNEHKDAKLNKVVVYDDFSNFETKHFKIDFYRVNHSIPDAFGVCV
QTPNGNIVESGDFRFDFAAGGEMLDVHKVVKIAERNVHVFMCETTNAEIPGFSQSEKLIYRNINKIIKEARGRVILTTFA
SNITRINEIIEIAVNNKRKVCLLGKSMDVNVNISRKIGLMDIDSNDIVEVRDIKNYPDRSILILCTGSQGEDSAALNTMA
RGKHNWVSLKSTDTIIMSSNPIPGNYAAVENLLNELSKYGVTIFENSPNMKLHASGHATQQELQLMLNLVFPRYLIPIHG
EYKMMRTIKNIAQECGINGDDVGLLANGQVMYLIDGKLYYSGEVINADPIYIESRNSSPDLARVIKQRQILSREGMFAVI
VVFDKNNNILGMPTLITRGCFFALDSSPLMTKITHSIKRGLENVIQNKRFNTREQMIKELKRVCKETVSYFIWKNKSRNP
LISTVLS*V

Specific function: Unknown

COG id: COG0595

COG function: function code R; Predicted hydrolase of the metallo-beta-lactamase superfamily

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. RNase J subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR011108
- InterPro:   IPR001587 [H]

Pfam domain/function: PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 63883; Mature: 63883

Theoretical pI: Translated: 7.81; Mature: 7.81

Prosite motif: PS00018 EF_HAND_1 ; PS01292 UPF0036

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKDFDPSEFVGKTPTKIFAFGGIQEVGKNMYGIEYDDEIIIIDCGIKFASDDLLGIDGI
CCCCCCCHHHCCCCCCEEEEECCHHHHCCCCCCCEECCEEEEEECCCEECCCCCEECCCC
IPSFEYLIENQAKVKALFITHGHEDHIGGVPYLLKQVDVPVIYAPRIAASLILKKVNEHK
CHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHCCCCEEECCHHHHHHHHHHHHCCC
DAKLNKVVVYDDFSNFETKHFKIDFYRVNHSIPDAFGVCVQTPNGNIVESGDFRFDFAAG
CCCCCEEEEEECCCCCCCEEEEEEEEEECCCCCCCCEEEEECCCCCEEECCCEEEEECCC
GEMLDVHKVVKIAERNVHVFMCETTNAEIPGFSQSEKLIYRNINKIIKEARGRVILTTFA
CCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEHH
SNITRINEIIEIAVNNKRKVCLLGKSMDVNVNISRKIGLMDIDSNDIVEVRDIKNYPDRS
HHHHHHHHHHEEEECCCEEEEEEECCEEEEEEEECEEEEEECCCCCEEEEEECCCCCCCE
ILILCTGSQGEDSAALNTMARGKHNWVSLKSTDTIIMSSNPIPGNYAAVENLLNELSKYG
EEEEEECCCCCCHHHHHHHHCCCCCEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHCC
VTIFENSPNMKLHASGHATQQELQLMLNLVFPRYLIPIHGEYKMMRTIKNIAQECGINGD
EEEEECCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCCC
DVGLLANGQVMYLIDGKLYYSGEVINADPIYIESRNSSPDLARVIKQRQILSREGMFAVI
CEEEEECCEEEEEECCEEEECCEEECCCCEEEECCCCCHHHHHHHHHHHHHCCCCCEEEE
VVFDKNNNILGMPTLITRGCFFALDSSPLMTKITHSIKRGLENVIQNKRFNTREQMIKEL
EEEECCCCEEECCHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
KRVCKETVSYFIWKNKSRNPLISTVLSV
HHHHHHHHHEEEECCCCCCHHHHHHHCC
>Mature Secondary Structure
MIKDFDPSEFVGKTPTKIFAFGGIQEVGKNMYGIEYDDEIIIIDCGIKFASDDLLGIDGI
CCCCCCCHHHCCCCCCEEEEECCHHHHCCCCCCCEECCEEEEEECCCEECCCCCEECCCC
IPSFEYLIENQAKVKALFITHGHEDHIGGVPYLLKQVDVPVIYAPRIAASLILKKVNEHK
CHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHCCCCEEECCHHHHHHHHHHHHCCC
DAKLNKVVVYDDFSNFETKHFKIDFYRVNHSIPDAFGVCVQTPNGNIVESGDFRFDFAAG
CCCCCEEEEEECCCCCCCEEEEEEEEEECCCCCCCCEEEEECCCCCEEECCCEEEEECCC
GEMLDVHKVVKIAERNVHVFMCETTNAEIPGFSQSEKLIYRNINKIIKEARGRVILTTFA
CCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEHH
SNITRINEIIEIAVNNKRKVCLLGKSMDVNVNISRKIGLMDIDSNDIVEVRDIKNYPDRS
HHHHHHHHHHEEEECCCEEEEEEECCEEEEEEEECEEEEEECCCCCEEEEEECCCCCCCE
ILILCTGSQGEDSAALNTMARGKHNWVSLKSTDTIIMSSNPIPGNYAAVENLLNELSKYG
EEEEEECCCCCCHHHHHHHHCCCCCEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHCC
VTIFENSPNMKLHASGHATQQELQLMLNLVFPRYLIPIHGEYKMMRTIKNIAQECGINGD
EEEEECCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCCC
DVGLLANGQVMYLIDGKLYYSGEVINADPIYIESRNSSPDLARVIKQRQILSREGMFAVI
CEEEEECCEEEEEECCEEEECCEEECCCCEEEECCCCCHHHHHHHHHHHHHCCCCCEEEE
VVFDKNNNILGMPTLITRGCFFALDSSPLMTKITHSIKRGLENVIQNKRFNTREQMIKEL
EEEECCCCEEECCHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
KRVCKETVSYFIWKNKSRNPLISTVLSV
HHHHHHHHHEEEECCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]