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The map label for this gene is pgsA [H]

Identifier: 13507992

GI number: 13507992

Start: 304361

End: 305044

Strand: Direct

Name: pgsA [H]

Synonym: MPN253

Alternate gene names: 13507992

Gene position: 304361-305044 (Clockwise)

Preceding gene: 13507991

Following gene: 13507993

Centisome position: 37.28

GC content: 37.87

Gene sequence:

>684_bases
ATGCGATCCCCTTTCCCCGTGCCCATGGTTCCATTAACTATTAAAACTTGACAGAAAAAGTTACCTAATTGGTTAACCAT
TTACCGCATTTTTATTGCTGTACCTACCATTATTTTTTTGGGATTAAATCACTTACTTGGTAGTGTTGCTAGTTTTACAG
TGTTAGGCAATGTCACCATTCACCTACAGGTTAGCCTTTTTATTGGGGGAGTCTTGTTTATTACCGCAGTTATTTCTGAT
TATTTAGATGGGTATTGAGCGCGGAAGTGAAGGGTTGTGTCTAACTTCGGTAAGCTGTGAGATCCGTTAGCTGACAAGGT
GATTATTAACGGTGTCTTAATTGCCCTAGTAGCATATGGCTACTTTCACTTTAGTTTTTTAATTGTGATTGTGCTGCGTG
ATTTAGTGCTAGACGGATTGCGCTTTTACGCTCAGGAAAAACAGCTAATTATTCCCGCCAACCAATGGGGTAAGTGAAAA
ACCACTTGACAAATGATAGCAATCTTAATGAGCTGTTTTGTGTTTAGTTTTTCTTTGAAGGAAACCAACAGTGCTAACAC
AAAAATCTTTTACTGAGCCATAGTGCATTTGCCCTATTATTTAGCTACAGCCTTCTCCTTGGTCTCGTTTGGTATTTACG
CCCAACAAATATATAAAACCATTAAGGTTAAAGTAAAGTTATAA

Upstream 100 bases:

>100_bases
TATTTAGATATGCGTAAATGGGGTTACTTTGCCTCAGCTGGCTTTGGTTTAGGGTTTGATCGTTTACTAGCTTACATCTG
TGGATTGGAAAACATCCGTG

Downstream 100 bases:

>100_bases
TTTTGGAACTTTCTTATTGTTGTGTACGCGCGCTTAATTGCTGAAAAACTGCTAAATCATAAGCTCACCATTGCCACTGC
AGAGTCAGTTACTGGGGGCC

Product: phosphatidylglycerophosphate synthase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MRSPFPVPMVPLTIKTWQKKLPNWLTIYRIFIAVPTIIFLGLNHLLGSVASFTVLGNVTIHLQVSLFIGGVLFITAVISD
YLDGYWARKWRVVSNFGKLWDPLADKVIINGVLIALVAYGYFHFSFLIVIVLRDLVLDGLRFYAQEKQLIIPANQWGKWK
TTWQMIAILMSCFVFSFSLKETNSANTKIFYWAIVHLPYYLATAFSLVSFGIYAQQIYKTIKVKVKL

Sequences:

>Translated_227_residues
MRSPFPVPMVPLTIKT*QKKLPNWLTIYRIFIAVPTIIFLGLNHLLGSVASFTVLGNVTIHLQVSLFIGGVLFITAVISD
YLDGY*ARK*RVVSNFGKL*DPLADKVIINGVLIALVAYGYFHFSFLIVIVLRDLVLDGLRFYAQEKQLIIPANQWGK*K
TT*QMIAILMSCFVFSFSLKETNSANTKIFY*AIVHLPYYLATAFSLVSFGIYAQQIYKTIKVKVKL
>Mature_227_residues
MRSPFPVPMVPLTIKT*QKKLPNWLTIYRIFIAVPTIIFLGLNHLLGSVASFTVLGNVTIHLQVSLFIGGVLFITAVISD
YLDGY*ARK*RVVSNFGKL*DPLADKVIINGVLIALVAYGYFHFSFLIVIVLRDLVLDGLRFYAQEKQLIIPANQWGK*K
TT*QMIAILMSCFVFSFSLKETNSANTKIFY*AIVHLPYYLATAFSLVSFGIYAQQIYKTIKVKVKL

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 24621; Mature: 24621

Theoretical pI: Translated: 10.35; Mature: 10.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSPFPVPMVPLTIKTQKKLPNWLTIYRIFIAVPTIIFLGLNHLLGSVASFTVLGNVTIH
CCCCCCCCEEEEEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECEEEE
LQVSLFIGGVLFITAVISDYLDGYARKRVVSNFGKLDPLADKVIINGVLIALVAYGYFHF
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SFLIVIVLRDLVLDGLRFYAQEKQLIIPANQWGKKTTQMIAILMSCFVFSFSLKETNSAN
HHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TKIFYAIVHLPYYLATAFSLVSFGIYAQQIYKTIKVKVKL
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEC
>Mature Secondary Structure
MRSPFPVPMVPLTIKTQKKLPNWLTIYRIFIAVPTIIFLGLNHLLGSVASFTVLGNVTIH
CCCCCCCCEEEEEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECEEEE
LQVSLFIGGVLFITAVISDYLDGYARKRVVSNFGKLDPLADKVIINGVLIALVAYGYFHF
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SFLIVIVLRDLVLDGLRFYAQEKQLIIPANQWGKKTTQMIAILMSCFVFSFSLKETNSAN
HHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TKIFYAIVHLPYYLATAFSLVSFGIYAQQIYKTIKVKVKL
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]