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The map label for this gene is hlyC [C]

Identifier: 13507898

GI number: 13507898

Start: 211982

End: 213256

Strand: Direct

Name: hlyC [C]

Synonym: MPN159

Alternate gene names: 13507898

Gene position: 211982-213256 (Clockwise)

Preceding gene: 13507897

Following gene: 13507899

Centisome position: 25.97

GC content: 42.59

Gene sequence:

>1275_bases
ATGGAAAGTGCCCCCAGTGGTGGCCTGTTGGCCTTAATTATTATCAGTATTATCCTCCTGGCTTGTATTAGTGCCGTGGT
TTCGGCTTACGAAACCGCCATTACCTCAATTACATCATACAAGTGGAGCAACTATGTCAAAACGCATAACAAGCAAAAGA
AGTTAACGACCAAGATTGTTAACCACTTCCAAAAGAACTATTCGGCTTGTTTAATTACCATCTTAGTGGCCAATAACATT
GTCGCCATTTTGGTTTCCAACATCCTCTTTTTGGCTTTAGATCAATCGATTAAGAATCCGGCCATTTCCAGTGCCTTGAA
CCTCTTAATTAGTGGGGTGTTATTGTTAATGCTGTGTGAAATTACTCCCAAAACCTTAGCACGGATTAACATCATCCGCG
TCTTGGTCTACTTTGCGGTGGTAGTGTATTTTTTCTACATCCTTTTTTGACCAATTACCAAGTTAGCCAGCATTATCTTT
GCCAAATACGAAAAGGCACCCCCAGTTTCCCGCCGTGATGTTTACTTCTTTATTGATGAAATTGAGCAAAACGGGTTATT
TACCAAAGAAGACGGGCAGCTAATTAAACGGACCCTAATCTTTGACCAGGTCTTAGTTGACCAAATCATGATTAAGTGAA
ACCGGGTGGTGTACTGTTATGAAGGTGATCCAGTCAAGACCATTAAGGAAAAGTTCTTGCACGGCCAGTTTTCCAGAATG
CCCGTACTCGACCAGACAAGCAATGAAGTGGTTGGTTTTATCCACCTCAAGGACTTGTTTAGTTCACTCGAAAAGAGCAA
CGAGCCGTTTGTTTTACAGGAGTTATTGTATCCAGCTGTTTTAGTAAGTAACACCACACCCATCAAGCAAGCTTTGCGCC
AAATGCGGTTACACCGGGCCCACTTAGCGGTCGTGCAGGACAAACACCACCACACGATCGGGATTGTTTCTATGGAAGAC
ATCATTGAGGAATTAGTCGGGGAAATTTACGATGAACATGATGAGGTGGAGGCAGTGCAAACGTTGGACAACAACACCTG
GTTAGTGTTACCGAACGTAAAAGCCGCCTTTTTCTTTAACAAGTGGATTAAACGGGATTTAGTAAAATCAAAAAACATGA
CGATCCAACGTTACTTGGCATCGTTTGAAAATGATGGGTTAAACACCCAGAATAAACTAGAAACGCCGTGGTTTATTGCT
GAAGCAATTGTCGACAGCGAGAACCCCGAGCAAATTCGGTACGAAATTCGCAAAAAGAGTGATGTTGTGGACTAG

Upstream 100 bases:

>100_bases
GTGCAAGCGTTGCAAAAAGCGATTAGTGGTGATTTAAAGCAAGCGCAGAAGTGGTTTGCTCAATCAACAAATTAAATAAA
ATTTAAACCTAATTTAACTT

Downstream 100 bases:

>100_bases
AGCCTTAATCTTAGAGTTAAAAACCAATAAGCAAAGCCGCTTGTTGTGGTTACTTGCAATTCCCTTACTAATATCGTTAA
CCTTACTAACGTACGGTTTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MESAPSGGLLALIIISIILLACISAVVSAYETAITSITSYKWSNYVKTHNKQKKLTTKIVNHFQKNYSACLITILVANNI
VAILVSNILFLALDQSIKNPAISSALNLLISGVLLLMLCEITPKTLARINIIRVLVYFAVVVYFFYILFWPITKLASIIF
AKYEKAPPVSRRDVYFFIDEIEQNGLFTKEDGQLIKRTLIFDQVLVDQIMIKWNRVVYCYEGDPVKTIKEKFLHGQFSRM
PVLDQTSNEVVGFIHLKDLFSSLEKSNEPFVLQELLYPAVLVSNTTPIKQALRQMRLHRAHLAVVQDKHHHTIGIVSMED
IIEELVGEIYDEHDEVEAVQTLDNNTWLVLPNVKAAFFFNKWIKRDLVKSKNMTIQRYLASFENDGLNTQNKLETPWFIA
EAIVDSENPEQIRYEIRKKSDVVD

Sequences:

>Translated_424_residues
MESAPSGGLLALIIISIILLACISAVVSAYETAITSITSYKWSNYVKTHNKQKKLTTKIVNHFQKNYSACLITILVANNI
VAILVSNILFLALDQSIKNPAISSALNLLISGVLLLMLCEITPKTLARINIIRVLVYFAVVVYFFYILF*PITKLASIIF
AKYEKAPPVSRRDVYFFIDEIEQNGLFTKEDGQLIKRTLIFDQVLVDQIMIK*NRVVYCYEGDPVKTIKEKFLHGQFSRM
PVLDQTSNEVVGFIHLKDLFSSLEKSNEPFVLQELLYPAVLVSNTTPIKQALRQMRLHRAHLAVVQDKHHHTIGIVSMED
IIEELVGEIYDEHDEVEAVQTLDNNTWLVLPNVKAAFFFNKWIKRDLVKSKNMTIQRYLASFENDGLNTQNKLETPWFIA
EAIVDSENPEQIRYEIRKKSDVVD
>Mature_424_residues
MESAPSGGLLALIIISIILLACISAVVSAYETAITSITSYKWSNYVKTHNKQKKLTTKIVNHFQKNYSACLITILVANNI
VAILVSNILFLALDQSIKNPAISSALNLLISGVLLLMLCEITPKTLARINIIRVLVYFAVVVYFFYILF*PITKLASIIF
AKYEKAPPVSRRDVYFFIDEIEQNGLFTKEDGQLIKRTLIFDQVLVDQIMIK*NRVVYCYEGDPVKTIKEKFLHGQFSRM
PVLDQTSNEVVGFIHLKDLFSSLEKSNEPFVLQELLYPAVLVSNTTPIKQALRQMRLHRAHLAVVQDKHHHTIGIVSMED
IIEELVGEIYDEHDEVEAVQTLDNNTWLVLPNVKAAFFFNKWIKRDLVKSKNMTIQRYLASFENDGLNTQNKLETPWFIA
EAIVDSENPEQIRYEIRKKSDVVD

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=356, Percent_Identity=24.438202247191, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI40068055, Length=340, Percent_Identity=22.0588235294118, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI40068053, Length=340, Percent_Identity=22.0588235294118, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1790664, Length=362, Percent_Identity=20.1657458563536, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1786879, Length=171, Percent_Identity=23.3918128654971, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI87082033, Length=162, Percent_Identity=27.1604938271605, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000644
- InterPro:   IPR002550 [H]

Pfam domain/function: PF00571 CBS; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 48120; Mature: 48120

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESAPSGGLLALIIISIILLACISAVVSAYETAITSITSYKWSNYVKTHNKQKKLTTKIV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
NHFQKNYSACLITILVANNIVAILVSNILFLALDQSIKNPAISSALNLLISGVLLLMLCE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
ITPKTLARINIIRVLVYFAVVVYFFYILFPITKLASIIFAKYEKAPPVSRRDVYFFIDEI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHH
EQNGLFTKEDGQLIKRTLIFDQVLVDQIMIKNRVVYCYEGDPVKTIKEKFLHGQFSRMPV
HCCCCEECCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHCCCHHCCCC
LDQTSNEVVGFIHLKDLFSSLEKSNEPFVLQELLYPAVLVSNTTPIKQALRQMRLHRAHL
CCCCCCCEEEEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
AVVQDKHHHTIGIVSMEDIIEELVGEIYDEHDEVEAVQTLDNNTWLVLPNVKAAFFFNKW
HHHCCCCCCEEEEEEHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEECCCHHHHHHHHH
IKRDLVKSKNMTIQRYLASFENDGLNTQNKLETPWFIAEAIVDSENPEQIRYEIRKKSDV
HHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCC
VD
CC
>Mature Secondary Structure
MESAPSGGLLALIIISIILLACISAVVSAYETAITSITSYKWSNYVKTHNKQKKLTTKIV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
NHFQKNYSACLITILVANNIVAILVSNILFLALDQSIKNPAISSALNLLISGVLLLMLCE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
ITPKTLARINIIRVLVYFAVVVYFFYILFPITKLASIIFAKYEKAPPVSRRDVYFFIDEI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHH
EQNGLFTKEDGQLIKRTLIFDQVLVDQIMIKNRVVYCYEGDPVKTIKEKFLHGQFSRMPV
HCCCCEECCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHCCCHHCCCC
LDQTSNEVVGFIHLKDLFSSLEKSNEPFVLQELLYPAVLVSNTTPIKQALRQMRLHRAHL
CCCCCCCEEEEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
AVVQDKHHHTIGIVSMEDIIEELVGEIYDEHDEVEAVQTLDNNTWLVLPNVKAAFFFNKW
HHHCCCCCCEEEEEEHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEECCCHHHHHHHHH
IKRDLVKSKNMTIQRYLASFENDGLNTQNKLETPWFIAEAIVDSENPEQIRYEIRKKSDV
HHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCC
VD
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]