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The map label for this gene is degU [H]

Identifier: 13488505

GI number: 13488505

Start: 132860

End: 133552

Strand: Direct

Name: degU [H]

Synonym: mlr9663

Alternate gene names: 13488505

Gene position: 132860-133552 (Clockwise)

Preceding gene: 13488504

Following gene: 13488507

Centisome position: 63.78

GC content: 61.76

Gene sequence:

>693_bases
ATGATTGGCACTATCCGCATCGCTATTGTCGACGATCATCCGCTGTTTCGCGAAGGCGTGACGCGCAGCCTGTCGGAGAT
CGGAGGTTTCGAGATCGTCGGCGAAGGCGCGACAGCGCAAGATGCCGAACGCATCGCCTCGACGGTGCAGCCCGACATAT
TGCTGCTCGACATCTCCATGCCGGGCGGCGGCCTGTCGGCGGTTGCAAGCATCCTTGCCGTCCATCCCGCCCAGAAGATC
GTCATGCTGACCGTTTCGGAGACCAATGCCGATGTAACCACGGCGCTGAACGCCGGCGTGCAGGGCTATATCCTCAAGGG
TGTCGGATCGCGCGCGCTTGCTGAAATCCTCCGCAACGTGGCGGCCGGCGAGAGCTATCTTTCGCCGATGTTGTCGGCGC
GGCTGCTTTCCGATCTCCAGTCCCCGCAATCCGCCAACGGCGTGGCGGACCGGTTGCGGCAGCTGACCGAACGGCAAACG
GAAATCCTGCGGCTGGTGGCGGAAGGGCTCTCAAACAAGGAGGTTGCCTTGCGCCTGGAGCTGCAGGAGAAGACGGTCAA
GCACCACATGACCGGGGTGCTGTCGAAACTCAATGTGCGAAACCGCACTGAGGCGGCTCTCATGATGCGCGACCGTGAAA
GGAACCCGCGCTCGAAAGCGCAAAAGAGGGTGCCATCAATCGGAGCTTCCTAA

Upstream 100 bases:

>100_bases
GCGGGCCGCGCCAAAACGGTTGAAGCGGACCGAACGCAATGGGTTCGCCGACGCATCAGCCAGCGGCGGTCGTCTCGAAA
ATACTGCCCGAGGAGCAAGC

Downstream 100 bases:

>100_bases
AAGGACTTTCCGGCCCGCATCATGGCCCGAGCAATGGCAAGCTGTGTTTCGGTCCTGGCGTTCTCTTTCTGGGTCATACT
GTCCGCCGCGATAAGCCGCT

Product: two-component response regulator

Products: NA

Alternate protein names: Protease production enhancer protein [H]

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MIGTIRIAIVDDHPLFREGVTRSLSEIGGFEIVGEGATAQDAERIASTVQPDILLLDISMPGGGLSAVASILAVHPAQKI
VMLTVSETNADVTTALNAGVQGYILKGVGSRALAEILRNVAAGESYLSPMLSARLLSDLQSPQSANGVADRLRQLTERQT
EILRLVAEGLSNKEVALRLELQEKTVKHHMTGVLSKLNVRNRTEAALMMRDRERNPRSKAQKRVPSIGAS

Sequences:

>Translated_230_residues
MIGTIRIAIVDDHPLFREGVTRSLSEIGGFEIVGEGATAQDAERIASTVQPDILLLDISMPGGGLSAVASILAVHPAQKI
VMLTVSETNADVTTALNAGVQGYILKGVGSRALAEILRNVAAGESYLSPMLSARLLSDLQSPQSANGVADRLRQLTERQT
EILRLVAEGLSNKEVALRLELQEKTVKHHMTGVLSKLNVRNRTEAALMMRDRERNPRSKAQKRVPSIGAS
>Mature_230_residues
MIGTIRIAIVDDHPLFREGVTRSLSEIGGFEIVGEGATAQDAERIASTVQPDILLLDISMPGGGLSAVASILAVHPAQKI
VMLTVSETNADVTTALNAGVQGYILKGVGSRALAEILRNVAAGESYLSPMLSARLLSDLQSPQSANGVADRLRQLTERQT
EILRLVAEGLSNKEVALRLELQEKTVKHHMTGVLSKLNVRNRTEAALMMRDRERNPRSKAQKRVPSIGAS

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=206, Percent_Identity=35.9223300970874, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI1788222, Length=202, Percent_Identity=32.6732673267327, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1787473, Length=204, Percent_Identity=36.2745098039216, Blast_Score=101, Evalue=3e-23,
Organism=Escherichia coli, GI1790102, Length=207, Percent_Identity=29.951690821256, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788546, Length=204, Percent_Identity=27.9411764705882, Blast_Score=80, Evalue=9e-17,
Organism=Escherichia coli, GI1786747, Length=199, Percent_Identity=23.6180904522613, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1788712, Length=193, Percent_Identity=22.7979274611399, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24694; Mature: 24694

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGTIRIAIVDDHPLFREGVTRSLSEIGGFEIVGEGATAQDAERIASTVQPDILLLDISM
CCCEEEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCCEEEEEECC
PGGGLSAVASILAVHPAQKIVMLTVSETNADVTTALNAGVQGYILKGVGSRALAEILRNV
CCCCHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHCCCCEEEECCCCHHHHHHHHHHH
AAGESYLSPMLSARLLSDLQSPQSANGVADRLRQLTERQTEILRLVAEGLSNKEVALRLE
HCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEE
LQEKTVKHHMTGVLSKLNVRNRTEAALMMRDRERNPRSKAQKRVPSIGAS
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure
MIGTIRIAIVDDHPLFREGVTRSLSEIGGFEIVGEGATAQDAERIASTVQPDILLLDISM
CCCEEEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCCEEEEEECC
PGGGLSAVASILAVHPAQKIVMLTVSETNADVTTALNAGVQGYILKGVGSRALAEILRNV
CCCCHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHCCCCEEEECCCCHHHHHHHHHHH
AAGESYLSPMLSARLLSDLQSPQSANGVADRLRQLTERQTEILRLVAEGLSNKEVALRLE
HCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEE
LQEKTVKHHMTGVLSKLNVRNRTEAALMMRDRERNPRSKAQKRVPSIGAS
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3136143; 3141378; 3141377; 9384377 [H]