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The map label for this gene is hipO [H]

Identifier: 13488238

GI number: 13488238

Start: 185848

End: 187023

Strand: Direct

Name: hipO [H]

Synonym: mlr9207

Alternate gene names: 13488238

Gene position: 185848-187023 (Clockwise)

Preceding gene: 13488356

Following gene: 13488239

Centisome position: 52.81

GC content: 58.76

Gene sequence:

>1176_bases
ATGCACTCAGTCGACGAGTTTTATCACCTGGCCGACGAGGTCACAGCTTGGCGCCGGCATCTTCATCAAAACCCCGAACT
CGACTTTGCCGTGCACGAGACGGCACGGTTTGTTGCGGACAAGCTGGCGTCATTTGGAATCAACCACATTGAAACTGGCA
TAGCCGGCACCGGCATCGTCGCTTTGATCCAGGGTGAGGGTGGCGAAGGGCCGACTATCGGCCTGCGTGCCGATATGGAC
GCATTGCCGATCCATGAAACGCCGGGAAAGGATTGGGCCTCGAAGACCCCCGGGAAGATGCACGCCTGCGGTCATGACGG
CCACACGTCGATGCTGCTTGGTGCTGCGAAGTACCTCGCTGGGAAACGGGATTTCAGGGGCGCCGTCGCGCTTATCTTCC
AGCCGGCCGAGGAGGTCGAATTGCCCTCGGGCGGGTTAAAGATGGTCGAGGACGGTTTTTTAGACCGTTTTCAAATCTCC
CAGGTCTTCGGCATGCACAACTGGCCAGGGATCGATGTCGGTAAGTTCGCCATTTGCGCAGGCCCTATGATGGCCTCCCA
GGATGATTTTGACATCGTTGTACAGGGTCGCGGCGGGCACGCTGCAGCCCCGCACTTAACAGTTGATCCCGTCGTTATCG
CCGCACAGGTCATTATAGGCCTGCAGGCTCTAGTGTCGCGCAGCACCGATCCAATCGAGTCACTGGTGATCTCAGTCACG
AAACTCCGCGCTTCGAATGCTTATAATGTGATTGCCGACGAAGTCGAACTTGCAGGAACAGTCCGCGCGTTGGCCCCTGT
CCTGCGCGACTTCGCTGAGACCCACTTAGAGACGACGGCTCGGAAAATCGCACAAGCTTTCGGAGGCGACATTTCTTACC
GCTACCGCCGATCGGTTCCAGCCACTGTGAACGACACCGCAGCCACCGCCCTTGCCATTCGTGCGGCGGGAGGCACCGGC
GCGACCGCAGTAGACGCGAAGTTGAAGCCGGTCATGGGCGCCGAGGATTTCGCTTACATGTTGCAGGCGCGCCAAGGGGC
CCTCATCTTCATCGGAAATGGTCCTTCGGCTGCGGTGCATAATGCCGGTTACGACTTTGACGACGCAGCAATTCCGTATG
GGGTGGCCTATTGGGCCAACGTCGTAGAGGTTACGCTTGGTGTTGGCGGCGGTTAA

Upstream 100 bases:

>100_bases
GCAAATTTCGCCCAAACCATTTCAAACGCTTGGGGCATTCTGCACATGGTACAAACCAGGGCCATATGATGGCCGCCAGA
CTTTGCTGAAGGGAGCCAGC

Downstream 100 bases:

>100_bases
CCGGCCGGGGCCGATCAGCCGCCCAGCACCAGCAAGGCAATTTGAAGAGCTCATTGCAAACCCCTGCCACTTGTGGACGA
TACGTTTCATGTCGTCTGAA

Product: hydrolase

Products: NA

Alternate protein names: Benzoylglycine amidohydrolase; Hippuricase [H]

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MHSVDEFYHLADEVTAWRRHLHQNPELDFAVHETARFVADKLASFGINHIETGIAGTGIVALIQGEGGEGPTIGLRADMD
ALPIHETPGKDWASKTPGKMHACGHDGHTSMLLGAAKYLAGKRDFRGAVALIFQPAEEVELPSGGLKMVEDGFLDRFQIS
QVFGMHNWPGIDVGKFAICAGPMMASQDDFDIVVQGRGGHAAAPHLTVDPVVIAAQVIIGLQALVSRSTDPIESLVISVT
KLRASNAYNVIADEVELAGTVRALAPVLRDFAETHLETTARKIAQAFGGDISYRYRRSVPATVNDTAATALAIRAAGGTG
ATAVDAKLKPVMGAEDFAYMLQARQGALIFIGNGPSAAVHNAGYDFDDAAIPYGVAYWANVVEVTLGVGGG

Sequences:

>Translated_391_residues
MHSVDEFYHLADEVTAWRRHLHQNPELDFAVHETARFVADKLASFGINHIETGIAGTGIVALIQGEGGEGPTIGLRADMD
ALPIHETPGKDWASKTPGKMHACGHDGHTSMLLGAAKYLAGKRDFRGAVALIFQPAEEVELPSGGLKMVEDGFLDRFQIS
QVFGMHNWPGIDVGKFAICAGPMMASQDDFDIVVQGRGGHAAAPHLTVDPVVIAAQVIIGLQALVSRSTDPIESLVISVT
KLRASNAYNVIADEVELAGTVRALAPVLRDFAETHLETTARKIAQAFGGDISYRYRRSVPATVNDTAATALAIRAAGGTG
ATAVDAKLKPVMGAEDFAYMLQARQGALIFIGNGPSAAVHNAGYDFDDAAIPYGVAYWANVVEVTLGVGGG
>Mature_391_residues
MHSVDEFYHLADEVTAWRRHLHQNPELDFAVHETARFVADKLASFGINHIETGIAGTGIVALIQGEGGEGPTIGLRADMD
ALPIHETPGKDWASKTPGKMHACGHDGHTSMLLGAAKYLAGKRDFRGAVALIFQPAEEVELPSGGLKMVEDGFLDRFQIS
QVFGMHNWPGIDVGKFAICAGPMMASQDDFDIVVQGRGGHAAAPHLTVDPVVIAAQVIIGLQALVSRSTDPIESLVISVT
KLRASNAYNVIADEVELAGTVRALAPVLRDFAETHLETTARKIAQAFGGDISYRYRRSVPATVNDTAATALAIRAAGGTG
ATAVDAKLKPVMGAEDFAYMLQARQGALIFIGNGPSAAVHNAGYDFDDAAIPYGVAYWANVVEVTLGVGGG

Specific function: Required But Not Essential For Aminobenzoyl-Glutamate Utilization. May Participate In Hydrolysis Of Aminobenzoyl- Glutamate To Aminobenzoate, Either Alone Or In Combination With Abgb. [C]

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20 family [H]

Homologues:

Organism=Escherichia coli, GI87081880, Length=430, Percent_Identity=24.4186046511628, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017439
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.32 [H]

Molecular weight: Translated: 41333; Mature: 41333

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSVDEFYHLADEVTAWRRHLHQNPELDFAVHETARFVADKLASFGINHIETGIAGTGIV
CCCHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHCCCHHHHCCCCCCCEE
ALIQGEGGEGPTIGLRADMDALPIHETPGKDWASKTPGKMHACGHDGHTSMLLGAAKYLA
EEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHC
GKRDFRGAVALIFQPAEEVELPSGGLKMVEDGFLDRFQISQVFGMHNWPGIDVGKFAICA
CCCCCCCEEEEEECCHHHCCCCCCCCHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCEEC
GPMMASQDDFDIVVQGRGGHAAAPHLTVDPVVIAAQVIIGLQALVSRSTDPIESLVISVT
CCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
KLRASNAYNVIADEVELAGTVRALAPVLRDFAETHLETTARKIAQAFGGDISYRYRRSVP
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCC
ATVNDTAATALAIRAAGGTGATAVDAKLKPVMGAEDFAYMLQARQGALIFIGNGPSAAVH
CCCCCHHHEEEEEEECCCCCCEEECCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCEE
NAGYDFDDAAIPYGVAYWANVVEVTLGVGGG
CCCCCCCCCCCCHHHHHHHHHHHEEEECCCC
>Mature Secondary Structure
MHSVDEFYHLADEVTAWRRHLHQNPELDFAVHETARFVADKLASFGINHIETGIAGTGIV
CCCHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHCCCHHHHCCCCCCCEE
ALIQGEGGEGPTIGLRADMDALPIHETPGKDWASKTPGKMHACGHDGHTSMLLGAAKYLA
EEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHC
GKRDFRGAVALIFQPAEEVELPSGGLKMVEDGFLDRFQISQVFGMHNWPGIDVGKFAICA
CCCCCCCEEEEEECCHHHCCCCCCCCHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCEEC
GPMMASQDDFDIVVQGRGGHAAAPHLTVDPVVIAAQVIIGLQALVSRSTDPIESLVISVT
CCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
KLRASNAYNVIADEVELAGTVRALAPVLRDFAETHLETTARKIAQAFGGDISYRYRRSVP
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCC
ATVNDTAATALAIRAAGGTGATAVDAKLKPVMGAEDFAYMLQARQGALIFIGNGPSAAVH
CCCCCHHHEEEEEEECCCCCCEEECCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCEE
NAGYDFDDAAIPYGVAYWANVVEVTLGVGGG
CCCCCCCCCCCCHHHHHHHHHHHEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7730270; 10688204 [H]