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The map label for this gene is hyuA [H]

Identifier: 13488078

GI number: 13488078

Start: 110162

End: 111709

Strand: Reverse

Name: hyuA [H]

Synonym: mll9131

Alternate gene names: 13488078

Gene position: 111709-110162 (Counterclockwise)

Preceding gene: 13488079

Following gene: 13488077

Centisome position: 31.74

GC content: 62.92

Gene sequence:

>1548_bases
ATGATTAGAATTGGGATCGATGTCGGTGGCACCAATACCGATGCCGTCGTGATGGATGGCACGCAAGTGGTGGCCGGCGT
CAAGTCCGCAACCACGGCCGATGTCATGAGCGGCGTCGTCAATGCGCTCAAGGATGTGCTGGCCGCATCCAGAATGGCAG
CAAGTGCCGTCGATGTGGTGATGATCGGCACCACGCATTTCACCAATGCCGTCGTACAGCGGCGCGATTTGGCGCCGACG
GCTGCGGTTCGCCTCGGCCTGCCAGCGACCGCCTCGCTGCCGCCGATGGTCGATTGGCCCGAGGACCTGAAGACGGCGAT
TGGCAACCATGCCTGGCTTGCCCATGGCGGCAATGAATTCGATGGTCGGGTGATCTCCCCGCTCAACGAAGAAGAGCTCT
TGGGCATCGCCGCGGAGATCAAGGTGAGAGGCATCAATTCGATCGCTATCACCTCGGTCCTATCGCCGGTTTCCAACGAA
TTCGAGAAGCGCGCCGCCGAGATTTTCGCCAAGGCGCTGCCGGGTGCGCATATCACCCTTTCCTCCGATATCGGCCGCAT
CGGCCTGCTCGAGCGCGAGAATGCCGCGATCATGAATGCTTGCCTGCGCGATCTCTCTGCGCACGTAATCGAAGCCTTCC
GCAAGGCCATTGCCGAGACCGGCATCAGGGGCCGCTTCTTCCTGACGCAGAATGACGGCACGCTTATGGACGCGGCCTTT
GCCGAGAAATTCCCGGTGCTGACCTTCGCCTCAGGGCCGACCAATTCCATGCGTGGCGCCGCTTTCCTGTCGGGTGTCGA
TGACGCTATCGTTGTCGATATCGGCGGCACGACGTCGGACGTCGGTTCGCTGCAGAACGGCTTTCCGCGCCAGGCGACAG
TCGCCGTCGAAGTGGGTGGGGTGCGCACCAATTTCCGCATGCCGGATGTGTTTTCGATTGGCCTCGGCGGCGGCTCGCTG
GTGGTGGACGGCGAACATGGCGTCAAGGTCGGCCCGACCTCGGTCGGTTATCGCATCAACACCGAGGCGCTGATTTTTGG
CGGCGAGACGCTGACCACGACCGACATCACCGTTGCTGCCGGCAATGCCGAGCTTGGCGACAAGGCCAGGGTGGCGCAAT
TGCCGAAAGACCTGCTCGACCGCACCCAGGCGAAAATCCTTTCCATGCTGGAGGATTGCGTGGAGCGCTCGCGCCTTTCG
CCGGACCCCCTTCCCGTCATCGTCGTCGGCGGCGGTTCGATCCTGGTCAATGGTCCGATCGGCGGCCTTGAGGTCATCAA
GCCCAACTATTTCGGTGTCGCCAATGCGGTCGGGGCTGCGATCGCCCAGGTCTCCGGCGAGATCGATCGTGTCTACGCGC
TGGCCGAAATCGGCCGCGATCAGGCGCTCGACGATGCCAAGGCGCGTGCCATCGATGCCGCCGTCGCCGCGGGCGCGTCA
CGCGACAGCGTCGAGATCGTCGATGTAGAGGATGTGCCGCTCGCCTATCTGCCAGGCAATGCCACGCGCGTGCGCGTCAA
AGCCGTGGGTGAATTGCATGTCGCGTGA

Upstream 100 bases:

>100_bases
GGTGAGATTCCGACGGCCGAGAAACTCATCGAACTCAGGGGAGCCTCCGCCGCCGCTCAGGCGTCGAATGCAAACAAGAC
TCCAATGAGGAACAACCAGG

Downstream 100 bases:

>100_bases
TCTTGGAAGACTCGAGGGAGCAGATCTCGTGCCGCTGGCGCTAGCGCTGCGCTCCTCGGCACCAACGACGGCAATCCATA
TATCGGCATGCTCCGGACCC

Product: hydantoinase

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 515; Mature: 515

Protein sequence:

>515_residues
MIRIGIDVGGTNTDAVVMDGTQVVAGVKSATTADVMSGVVNALKDVLAASRMAASAVDVVMIGTTHFTNAVVQRRDLAPT
AAVRLGLPATASLPPMVDWPEDLKTAIGNHAWLAHGGNEFDGRVISPLNEEELLGIAAEIKVRGINSIAITSVLSPVSNE
FEKRAAEIFAKALPGAHITLSSDIGRIGLLERENAAIMNACLRDLSAHVIEAFRKAIAETGIRGRFFLTQNDGTLMDAAF
AEKFPVLTFASGPTNSMRGAAFLSGVDDAIVVDIGGTTSDVGSLQNGFPRQATVAVEVGGVRTNFRMPDVFSIGLGGGSL
VVDGEHGVKVGPTSVGYRINTEALIFGGETLTTTDITVAAGNAELGDKARVAQLPKDLLDRTQAKILSMLEDCVERSRLS
PDPLPVIVVGGGSILVNGPIGGLEVIKPNYFGVANAVGAAIAQVSGEIDRVYALAEIGRDQALDDAKARAIDAAVAAGAS
RDSVEIVDVEDVPLAYLPGNATRVRVKAVGELHVA

Sequences:

>Translated_515_residues
MIRIGIDVGGTNTDAVVMDGTQVVAGVKSATTADVMSGVVNALKDVLAASRMAASAVDVVMIGTTHFTNAVVQRRDLAPT
AAVRLGLPATASLPPMVDWPEDLKTAIGNHAWLAHGGNEFDGRVISPLNEEELLGIAAEIKVRGINSIAITSVLSPVSNE
FEKRAAEIFAKALPGAHITLSSDIGRIGLLERENAAIMNACLRDLSAHVIEAFRKAIAETGIRGRFFLTQNDGTLMDAAF
AEKFPVLTFASGPTNSMRGAAFLSGVDDAIVVDIGGTTSDVGSLQNGFPRQATVAVEVGGVRTNFRMPDVFSIGLGGGSL
VVDGEHGVKVGPTSVGYRINTEALIFGGETLTTTDITVAAGNAELGDKARVAQLPKDLLDRTQAKILSMLEDCVERSRLS
PDPLPVIVVGGGSILVNGPIGGLEVIKPNYFGVANAVGAAIAQVSGEIDRVYALAEIGRDQALDDAKARAIDAAVAAGAS
RDSVEIVDVEDVPLAYLPGNATRVRVKAVGELHVA
>Mature_515_residues
MIRIGIDVGGTNTDAVVMDGTQVVAGVKSATTADVMSGVVNALKDVLAASRMAASAVDVVMIGTTHFTNAVVQRRDLAPT
AAVRLGLPATASLPPMVDWPEDLKTAIGNHAWLAHGGNEFDGRVISPLNEEELLGIAAEIKVRGINSIAITSVLSPVSNE
FEKRAAEIFAKALPGAHITLSSDIGRIGLLERENAAIMNACLRDLSAHVIEAFRKAIAETGIRGRFFLTQNDGTLMDAAF
AEKFPVLTFASGPTNSMRGAAFLSGVDDAIVVDIGGTTSDVGSLQNGFPRQATVAVEVGGVRTNFRMPDVFSIGLGGGSL
VVDGEHGVKVGPTSVGYRINTEALIFGGETLTTTDITVAAGNAELGDKARVAQLPKDLLDRTQAKILSMLEDCVERSRLS
PDPLPVIVVGGGSILVNGPIGGLEVIKPNYFGVANAVGAAIAQVSGEIDRVYALAEIGRDQALDDAKARAIDAAVAAGAS
RDSVEIVDVEDVPLAYLPGNATRVRVKAVGELHVA

Specific function: HyuA and hyuB convert D- and L-substituted hydantoins to corresponding N-carbamyl-amino acids [H]

COG id: COG0145

COG function: function code EQ; N-methylhydantoinase A/acetone carboxylase, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008040
- InterPro:   IPR002821 [H]

Pfam domain/function: PF05378 Hydant_A_N; PF01968 Hydantoinase_A [H]

EC number: NA

Molecular weight: Translated: 53426; Mature: 53426

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRIGIDVGGTNTDAVVMDGTQVVAGVKSATTADVMSGVVNALKDVLAASRMAASAVDVV
CEEEEEEECCCCCCEEEECCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
MIGTTHFTNAVVQRRDLAPTAAVRLGLPATASLPPMVDWPEDLKTAIGNHAWLAHGGNEF
EECCHHHHHHHHHHHCCCCHHHEEECCCCCCCCCCCCCCCHHHHHHHCCCEEEECCCCCC
DGRVISPLNEEELLGIAAEIKVRGINSIAITSVLSPVSNEFEKRAAEIFAKALPGAHITL
CCEEECCCCHHHHHEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
SSDIGRIGLLERENAAIMNACLRDLSAHVIEAFRKAIAETGIRGRFFLTQNDGTLMDAAF
ECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEHHH
AEKFPVLTFASGPTNSMRGAAFLSGVDDAIVVDIGGTTSDVGSLQNGFPRQATVAVEVGG
HCCCCEEEECCCCCCCCCCHHHHCCCCCEEEEEECCCCHHHHHHHCCCCCCEEEEEEECC
VRTNFRMPDVFSIGLGGGSLVVDGEHGVKVGPTSVGYRINTEALIFGGETLTTTDITVAA
EEECCCCCCEEEEECCCCEEEEECCCCCEECCCCCCEEECCEEEEECCCEEEEEEEEEEE
GNAELGDKARVAQLPKDLLDRTQAKILSMLEDCVERSRLSPDPLPVIVVGGGSILVNGPI
CCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEEECCC
GGLEVIKPNYFGVANAVGAAIAQVSGEIDRVYALAEIGRDQALDDAKARAIDAAVAAGAS
CCEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCC
RDSVEIVDVEDVPLAYLPGNATRVRVKAVGELHVA
CCCEEEEEECCCCEEEECCCCEEEEEEEECEEECC
>Mature Secondary Structure
MIRIGIDVGGTNTDAVVMDGTQVVAGVKSATTADVMSGVVNALKDVLAASRMAASAVDVV
CEEEEEEECCCCCCEEEECCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
MIGTTHFTNAVVQRRDLAPTAAVRLGLPATASLPPMVDWPEDLKTAIGNHAWLAHGGNEF
EECCHHHHHHHHHHHCCCCHHHEEECCCCCCCCCCCCCCCHHHHHHHCCCEEEECCCCCC
DGRVISPLNEEELLGIAAEIKVRGINSIAITSVLSPVSNEFEKRAAEIFAKALPGAHITL
CCEEECCCCHHHHHEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
SSDIGRIGLLERENAAIMNACLRDLSAHVIEAFRKAIAETGIRGRFFLTQNDGTLMDAAF
ECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEHHH
AEKFPVLTFASGPTNSMRGAAFLSGVDDAIVVDIGGTTSDVGSLQNGFPRQATVAVEVGG
HCCCCEEEECCCCCCCCCCHHHHCCCCCEEEEEECCCCHHHHHHHCCCCCCEEEEEEECC
VRTNFRMPDVFSIGLGGGSLVVDGEHGVKVGPTSVGYRINTEALIFGGETLTTTDITVAA
EEECCCCCCEEEEECCCCEEEEECCCCCEECCCCCCEEECCEEEEECCCEEEEEEEEEEE
GNAELGDKARVAQLPKDLLDRTQAKILSMLEDCVERSRLSPDPLPVIVVGGGSILVNGPI
CCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEEECCC
GGLEVIKPNYFGVANAVGAAIAQVSGEIDRVYALAEIGRDQALDDAKARAIDAAVAAGAS
CCEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCC
RDSVEIVDVEDVPLAYLPGNATRVRVKAVGELHVA
CCCEEEEEECCCCEEEECCCCEEEEEEEECEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1732229 [H]