Click here to switch to the map view.

The map label for this gene is budC [H]

Identifier: 13476554

GI number: 13476554

Start: 6534742

End: 6535506

Strand: Direct

Name: budC [H]

Synonym: mlr7910

Alternate gene names: 13476554

Gene position: 6534742-6535506 (Clockwise)

Preceding gene: 13476552

Following gene: 13476555

Centisome position: 92.87

GC content: 64.44

Gene sequence:

>765_bases
ATGAGCAAAGCCACTGCCGCGGCCCTGGTGACGGGCGGGGCGAAACGGATCGGCAAGGCAATTGTCGAAGACCTCGCCGG
CCATGGTTTTGCCGTCGCCATCCACGCCAATCGCTCGCAGGGCGAGGCGGATGCCTTGGCGGCGGGGATCAACCAGTCTG
GCGGCCGCGCCACCGTGGTTGGGGCGGACTTGACCGACACGAATGCTGTCGCCGGCCTCGTTGGTCAGGCGGAGGCCGCG
TTGGGGCCGATCTCGCTGCTGGTCAACAATGCTTCGCTTTTCGTCGATGATTCGATCGAGGATTTCGATTGGCAGGCCTG
GGACCGCCACTTTGCCATCCACGTGAAAACGCCGGCGCTGTTGGCGCGGAATTTCGCCCGCGCCTTGCCCGAAGGGCGCG
AGGGGCTGATCGTCAACATCATCGATCAGCGCGTCTGGCGCCCGACGCCACGCTACTTCTCCTACGCGCTGTCGAAGTCG
GCTTTGTGGACCCAGACGCAGATGCTGGCGCAGGCGCTCGGCCCGCGCATTCGTGTCAACGCGATCGGTCCTGGCCCGAC
ACTGAAGAATGTGCGCCAGGACGATTCCGATTTTGACGCACAGCTCGCTGGCCTGATCCTGAAGCGCGGCCCGGAATTGC
CGGAATTCGGCGCCACCATCCGCTATCTCTGGGATGCGCGCTCGGTCACCGGTCAGATGATCGCGCTCGATGGCGGCCAG
CATCTTGCATGGCAGACGCCCGATGTGACAGGCATGACGGAATGA

Upstream 100 bases:

>100_bases
TCGCCACAATGCTGCCCCAAGTGCGAATGCCGTTTAACGCATGCCGGGCCATATTTCGTCGGCGTCGTGTTTTCGGGCCG
AAATTGAGGATTGACAGCAG

Downstream 100 bases:

>100_bases
GTCCTTTAGACCAAAAGAACAAGCCGCGTGGCGGGGCCGATGACCTGCCTCCCGAAATCGACCTTGAGGATGAGGCGCTG
GAGGAGATCGTCGAACCGAC

Product: short chain dehydrogenase

Products: NA

Alternate protein names: Acetoin(diacetyl) reductase; AR; Meso-2,3-butanediol dehydrogenase [H]

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MSKATAAALVTGGAKRIGKAIVEDLAGHGFAVAIHANRSQGEADALAAGINQSGGRATVVGADLTDTNAVAGLVGQAEAA
LGPISLLVNNASLFVDDSIEDFDWQAWDRHFAIHVKTPALLARNFARALPEGREGLIVNIIDQRVWRPTPRYFSYALSKS
ALWTQTQMLAQALGPRIRVNAIGPGPTLKNVRQDDSDFDAQLAGLILKRGPELPEFGATIRYLWDARSVTGQMIALDGGQ
HLAWQTPDVTGMTE

Sequences:

>Translated_254_residues
MSKATAAALVTGGAKRIGKAIVEDLAGHGFAVAIHANRSQGEADALAAGINQSGGRATVVGADLTDTNAVAGLVGQAEAA
LGPISLLVNNASLFVDDSIEDFDWQAWDRHFAIHVKTPALLARNFARALPEGREGLIVNIIDQRVWRPTPRYFSYALSKS
ALWTQTQMLAQALGPRIRVNAIGPGPTLKNVRQDDSDFDAQLAGLILKRGPELPEFGATIRYLWDARSVTGQMIALDGGQ
HLAWQTPDVTGMTE
>Mature_253_residues
SKATAAALVTGGAKRIGKAIVEDLAGHGFAVAIHANRSQGEADALAAGINQSGGRATVVGADLTDTNAVAGLVGQAEAAL
GPISLLVNNASLFVDDSIEDFDWQAWDRHFAIHVKTPALLARNFARALPEGREGLIVNIIDQRVWRPTPRYFSYALSKSA
LWTQTQMLAQALGPRIRVNAIGPGPTLKNVRQDDSDFDAQLAGLILKRGPELPEFGATIRYLWDARSVTGQMIALDGGQH
LAWQTPDVTGMTE

Specific function: Catalyzes the reversible reduction of (S)-acetoin to 2,3-butanediol in the presence of NADH [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7705925, Length=239, Percent_Identity=30.1255230125523, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI32483357, Length=245, Percent_Identity=29.3877551020408, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI2367175, Length=247, Percent_Identity=31.5789473684211, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1787891, Length=237, Percent_Identity=28.6919831223629, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789378, Length=248, Percent_Identity=29.0322580645161, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788459, Length=243, Percent_Identity=29.6296296296296, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI2367365, Length=234, Percent_Identity=30.7692307692308, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI87082100, Length=261, Percent_Identity=32.183908045977, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789208, Length=195, Percent_Identity=31.2820512820513, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787335, Length=245, Percent_Identity=26.1224489795918, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790717, Length=247, Percent_Identity=26.3157894736842, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI115534694, Length=239, Percent_Identity=32.6359832635983, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71994604, Length=249, Percent_Identity=27.3092369477912, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI23397609, Length=253, Percent_Identity=27.6679841897233, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28571526, Length=247, Percent_Identity=29.5546558704453, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21357041, Length=245, Percent_Identity=30.2040816326531, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014007
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.304 [H]

Molecular weight: Translated: 27074; Mature: 26943

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKATAAALVTGGAKRIGKAIVEDLAGHGFAVAIHANRSQGEADALAAGINQSGGRATVV
CCCHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHCCCCCCCEEEEE
GADLTDTNAVAGLVGQAEAALGPISLLVNNASLFVDDSIEDFDWQAWDRHFAIHVKTPAL
ECCCCCCHHHHHHHHHHHHHHCCEEEEEECCEEEEECCCCCCCCCCCCCEEEEEECCHHH
LARNFARALPEGREGLIVNIIDQRVWRPTPRYFSYALSKSALWTQTQMLAQALGPRIRVN
HHHHHHHHCCCCCCCEEEEEEHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEE
AIGPGPTLKNVRQDDSDFDAQLAGLILKRGPELPEFGATIRYLWDARSVTGQMIALDGGQ
EECCCCCHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCEEEEEECCC
HLAWQTPDVTGMTE
EEEEECCCCCCCCC
>Mature Secondary Structure 
SKATAAALVTGGAKRIGKAIVEDLAGHGFAVAIHANRSQGEADALAAGINQSGGRATVV
CCHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHCCCCCCCEEEEE
GADLTDTNAVAGLVGQAEAALGPISLLVNNASLFVDDSIEDFDWQAWDRHFAIHVKTPAL
ECCCCCCHHHHHHHHHHHHHHCCEEEEEECCEEEEECCCCCCCCCCCCCEEEEEECCHHH
LARNFARALPEGREGLIVNIIDQRVWRPTPRYFSYALSKSALWTQTQMLAQALGPRIRVN
HHHHHHHHCCCCCCCEEEEEEHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEE
AIGPGPTLKNVRQDDSDFDAQLAGLILKRGPELPEFGATIRYLWDARSVTGQMIALDGGQ
EECCCCCHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCEEEEEECCC
HLAWQTPDVTGMTE
EEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11173520 [H]