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The map label for this gene is fabD [H]

Identifier: 13476513

GI number: 13476513

Start: 6496040

End: 6496987

Strand: Direct

Name: fabD [H]

Synonym: mlr7849

Alternate gene names: 13476513

Gene position: 6496040-6496987 (Clockwise)

Preceding gene: 13476511

Following gene: 13476514

Centisome position: 92.32

GC content: 67.51

Gene sequence:

>948_bases
ATGGCCGTCGCATTCACCTTTCCGGGACAAGGCAGCCAGGCTGTCGGCATGGGCAAGGACCTCGCCGATGCCTTTCCCGA
GGCGCGCAGGGTCTTCCAGGAAGTCGACGACGCGCTCGGCGAGAACCTGTCGAAGCTGATCTGGGAAGGTCCGGAGGAGA
CCTTGACGCTGACGGCCAATGCGCAGCCGGCGCTGATGGCGGTTTCGTTGGCGGCGATCAGGGCGCTGGAAGCGCGCGGT
TTTTCGCTGAAGGACAAGGTCGCCTATGTCGCCGGCCATTCGCTGGGCGAATATTCGGCCCTTGCCGCAGCCGGCTTCGT
TTCCGTCGCCGATGCGGCCCGGCTGCTGCGCATTCGTGGCAACGCCATGCAGGCGGCGGTGCCGGCCGGCGAGGGCGCCA
TGGCGGCGATCATCGGACTGGAGCAGCCAGATGTCGAAGCCGCTTGCATCGAGGCCGCGCAAGGGGCCAGCAAGGTCTGC
CAGATCGCCAATGACAATGGCGGCGGCCAGCTGGTCATCTCCGGCGCCAAGGCCGCGGTCGAGCTGGCTGCCAAATTGTG
CACCGAAAAGGGCGCCAAGCGGGCTCTGATGCTGCAGGTCTCGGCGCCCTTCCATTCGGCGCTGATGGCACCGGCTGCCA
ATGTCATGCGCGAGGCGCTCGCCGGTGTGACGAAGCATGCGCCGGGGGTGCCAGTGGTGTCCAACGTCACGGTGACCCCG
ACCAGCGATCCCGACGAGATCGCCCGGCGCCTGGTCGAGCAGATCACCGGCCGCGTGCGCTGGCGCGAAACAGTCGAATG
GTTCGGCGCCAACGGCGTCACCACGCTTTACGAGATCGGCGCCGGCAAGGTGCTGTCGGGCCTGGCTCGGCGCATCAACC
GCGACATCGCGACATCGGCCGTCGGCACGCCGGCCGATGTCGAGGCCGCGCTGGCCACATTCGCATAA

Upstream 100 bases:

>100_bases
TCCGGGGTGAACCGGGCTTGACTTGGCGGCCCGCCTTGCGCCACAGGCAGGGAAAATTCGTGTTATCAGCCAAGTAAAAC
CAGTCTTCGGGAGCCCTCGC

Downstream 100 bases:

>100_bases
TCCACTGGCGATTTGACCCCACCCGTGTGAAGGGTGTTTTCTCAGATCAGGAGACGAAAATGTTCGAACTGACCGGCCGC
AAGGCGCTCGTCACCGGCGC

Product: acyl-carrier-protein S-malonyltransferase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MAVAFTFPGQGSQAVGMGKDLADAFPEARRVFQEVDDALGENLSKLIWEGPEETLTLTANAQPALMAVSLAAIRALEARG
FSLKDKVAYVAGHSLGEYSALAAAGFVSVADAARLLRIRGNAMQAAVPAGEGAMAAIIGLEQPDVEAACIEAAQGASKVC
QIANDNGGGQLVISGAKAAVELAAKLCTEKGAKRALMLQVSAPFHSALMAPAANVMREALAGVTKHAPGVPVVSNVTVTP
TSDPDEIARRLVEQITGRVRWRETVEWFGANGVTTLYEIGAGKVLSGLARRINRDIATSAVGTPADVEAALATFA

Sequences:

>Translated_315_residues
MAVAFTFPGQGSQAVGMGKDLADAFPEARRVFQEVDDALGENLSKLIWEGPEETLTLTANAQPALMAVSLAAIRALEARG
FSLKDKVAYVAGHSLGEYSALAAAGFVSVADAARLLRIRGNAMQAAVPAGEGAMAAIIGLEQPDVEAACIEAAQGASKVC
QIANDNGGGQLVISGAKAAVELAAKLCTEKGAKRALMLQVSAPFHSALMAPAANVMREALAGVTKHAPGVPVVSNVTVTP
TSDPDEIARRLVEQITGRVRWRETVEWFGANGVTTLYEIGAGKVLSGLARRINRDIATSAVGTPADVEAALATFA
>Mature_314_residues
AVAFTFPGQGSQAVGMGKDLADAFPEARRVFQEVDDALGENLSKLIWEGPEETLTLTANAQPALMAVSLAAIRALEARGF
SLKDKVAYVAGHSLGEYSALAAAGFVSVADAARLLRIRGNAMQAAVPAGEGAMAAIIGLEQPDVEAACIEAAQGASKVCQ
IANDNGGGQLVISGAKAAVELAAKLCTEKGAKRALMLQVSAPFHSALMAPAANVMREALAGVTKHAPGVPVVSNVTVTPT
SDPDEIARRLVEQITGRVRWRETVEWFGANGVTTLYEIGAGKVLSGLARRINRDIATSAVGTPADVEAALATFA

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=297, Percent_Identity=33.6700336700337, Blast_Score=158, Evalue=6e-39,
Organism=Homo sapiens, GI27477045, Length=107, Percent_Identity=40.1869158878505, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1787334, Length=308, Percent_Identity=48.7012987012987, Blast_Score=243, Evalue=9e-66,
Organism=Caenorhabditis elegans, GI71984332, Length=293, Percent_Identity=30.7167235494881, Blast_Score=127, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI17550940, Length=294, Percent_Identity=29.5918367346939, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24665753, Length=307, Percent_Identity=35.8306188925081, Blast_Score=141, Evalue=5e-34,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 32475; Mature: 32344

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVAFTFPGQGSQAVGMGKDLADAFPEARRVFQEVDDALGENLSKLIWEGPEETLTLTAN
CEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
AQPALMAVSLAAIRALEARGFSLKDKVAYVAGHSLGEYSALAAAGFVSVADAARLLRIRG
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
NAMQAAVPAGEGAMAAIIGLEQPDVEAACIEAAQGASKVCQIANDNGGGQLVISGAKAAV
CHHEEECCCCCCCEEEEEECCCCCHHHHHHHHHCCHHHHHHHCCCCCCCEEEEECHHHHH
ELAAKLCTEKGAKRALMLQVSAPFHSALMAPAANVMREALAGVTKHAPGVPVVSNVTVTP
HHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCEEECC
TSDPDEIARRLVEQITGRVRWRETVEWFGANGVTTLYEIGAGKVLSGLARRINRDIATSA
CCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHC
VGTPADVEAALATFA
CCCCHHHHHHHHHCC
>Mature Secondary Structure 
AVAFTFPGQGSQAVGMGKDLADAFPEARRVFQEVDDALGENLSKLIWEGPEETLTLTAN
EEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
AQPALMAVSLAAIRALEARGFSLKDKVAYVAGHSLGEYSALAAAGFVSVADAARLLRIRG
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
NAMQAAVPAGEGAMAAIIGLEQPDVEAACIEAAQGASKVCQIANDNGGGQLVISGAKAAV
CHHEEECCCCCCCEEEEEECCCCCHHHHHHHHHCCHHHHHHHCCCCCCCEEEEECHHHHH
ELAAKLCTEKGAKRALMLQVSAPFHSALMAPAANVMREALAGVTKHAPGVPVVSNVTVTP
HHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCEEECC
TSDPDEIARRLVEQITGRVRWRETVEWFGANGVTTLYEIGAGKVLSGLARRINRDIATSA
CCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHC
VGTPADVEAALATFA
CCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]