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The map label for this gene is era

Identifier: 13476443

GI number: 13476443

Start: 6429066

End: 6429998

Strand: Direct

Name: era

Synonym: mlr7766

Alternate gene names: 13476443

Gene position: 6429066-6429998 (Clockwise)

Preceding gene: 161621443

Following gene: 13476444

Centisome position: 91.37

GC content: 62.81

Gene sequence:

>933_bases
ATGGAACGCGGCATGACCGATATTGAAACTGCAGAAACCCCCGCCACGCATTCCGGCTTCGTCGCGCTGATCGGCGCGCC
GAATGCCGGCAAGTCGACGCTGGTCAACCAGTTGGTCGGCGCCAAGGTGTCGATCGTCACCCACAAGGTGCAGACGACGC
GTGCCATCGTGCGCGGCATCGCCACGCATGACAATGCGCAGATCGTCTTCGTCGACACGCCGGGCATCTTCAAGCCCAAG
CGGCGCCTCGACACCGCGATGGTGACCACCGCCTGGGGCGGCGCCAAGGATGCCGATATCGTGCTTTTGCTGATCGATGC
CGAACGCGGCATCCGGGGTGATGCCGATGCCATTCTCGAACGGCTGAAGGATGTGCGCCAGCCGATGGCGCTGATCCTCA
ACAAGGTCGATCGGGTCAAGCACGAGACGCTTCTGGCCCTGTCCGCGGCGGCGAACGAGAAAGTGCCGTTCAAGCGCACC
TTCATGGTCTCGGCGCTGACCGGCTCCGGCTGCAAGGACCTGCTCGACTATCTGGCGCAGGCGCTGCCGGCCGGCCCCTG
GTACTATCCGGAGGACCAGATTTCCGACCTGCCGATGCGGCAACTGGCGGCCGAGATCACCCGCGAAAAGCTGTATCTGC
GGCTGCATCAGGAACTGCCCTATTCCTCGCATATCGAGACAGAGAAATGGGAAGAGAAGCCGGATGGCTCGGTGCGCATC
GACCAGACCATCTATGTCGAGCGCGACAGCCAGAAGAAGATCGTGCTCGGCCACAAGGGCGAAACCATCCGTGCCATCGG
CCAGGCGGCGCGCATGGAGATCGCAGGCATCCTCGAGCAGAAAGTGCACCTCTTCCTGTTCGTCAAGGTGCGCGAGAACT
GGGGCGACGATCCAGAGCGTTACCGCGAGATGGGGCTCGAATTCCCGCACTAG

Upstream 100 bases:

>100_bases
GTGTGAGGGTCGGTGCATTTCAGCCGGCGACCGGCAGCGGTCGTTCTAAACGTGAAGCGGAGCAGGCAGCCGCGGCTGCC
CTTCTGCTGCGCGAAGGTGT

Downstream 100 bases:

>100_bases
CGGCCTGGCGTGTCATCGATGCGGTGCTGGCTGACCGCAGGCGCTGGACATGATGTGATTCTCGACCGTCATTGTTCTCG
TTCGCGCACCTGTCGCACTG

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MERGMTDIETAETPATHSGFVALIGAPNAGKSTLVNQLVGAKVSIVTHKVQTTRAIVRGIATHDNAQIVFVDTPGIFKPK
RRLDTAMVTTAWGGAKDADIVLLLIDAERGIRGDADAILERLKDVRQPMALILNKVDRVKHETLLALSAAANEKVPFKRT
FMVSALTGSGCKDLLDYLAQALPAGPWYYPEDQISDLPMRQLAAEITREKLYLRLHQELPYSSHIETEKWEEKPDGSVRI
DQTIYVERDSQKKIVLGHKGETIRAIGQAARMEIAGILEQKVHLFLFVKVRENWGDDPERYREMGLEFPH

Sequences:

>Translated_310_residues
MERGMTDIETAETPATHSGFVALIGAPNAGKSTLVNQLVGAKVSIVTHKVQTTRAIVRGIATHDNAQIVFVDTPGIFKPK
RRLDTAMVTTAWGGAKDADIVLLLIDAERGIRGDADAILERLKDVRQPMALILNKVDRVKHETLLALSAAANEKVPFKRT
FMVSALTGSGCKDLLDYLAQALPAGPWYYPEDQISDLPMRQLAAEITREKLYLRLHQELPYSSHIETEKWEEKPDGSVRI
DQTIYVERDSQKKIVLGHKGETIRAIGQAARMEIAGILEQKVHLFLFVKVRENWGDDPERYREMGLEFPH
>Mature_310_residues
MERGMTDIETAETPATHSGFVALIGAPNAGKSTLVNQLVGAKVSIVTHKVQTTRAIVRGIATHDNAQIVFVDTPGIFKPK
RRLDTAMVTTAWGGAKDADIVLLLIDAERGIRGDADAILERLKDVRQPMALILNKVDRVKHETLLALSAAANEKVPFKRT
FMVSALTGSGCKDLLDYLAQALPAGPWYYPEDQISDLPMRQLAAEITREKLYLRLHQELPYSSHIETEKWEEKPDGSVRI
DQTIYVERDSQKKIVLGHKGETIRAIGQAARMEIAGILEQKVHLFLFVKVRENWGDDPERYREMGLEFPH

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain

Homologues:

Organism=Homo sapiens, GI24307899, Length=320, Percent_Identity=32.8125, Blast_Score=141, Evalue=8e-34,
Organism=Escherichia coli, GI1788919, Length=292, Percent_Identity=37.3287671232877, Blast_Score=190, Evalue=9e-50,
Organism=Escherichia coli, GI87082120, Length=167, Percent_Identity=28.1437125748503, Blast_Score=70, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24646434, Length=307, Percent_Identity=29.6416938110749, Blast_Score=99, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ERA_RHILO (Q985A5)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_108013.1
- ProteinModelPortal:   Q985A5
- SMR:   Q985A5
- GeneID:   1230668
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mlr7766
- NMPDR:   fig|266835.1.peg.6114
- HOGENOM:   HBG561652
- OMA:   AKDWQRD
- ProtClustDB:   PRK00089
- GO:   GO:0005737
- HAMAP:   MF_00367
- InterPro:   IPR005662
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- TIGRFAMs:   TIGR00436
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1; SSF54814 KH_prok

EC number: NA

Molecular weight: Translated: 34613; Mature: 34613

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERGMTDIETAETPATHSGFVALIGAPNAGKSTLVNQLVGAKVSIVTHKVQTTRAIVRGI
CCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCEEEEEEHHHHHHHHHHHHH
ATHDNAQIVFVDTPGIFKPKRRLDTAMVTTAWGGAKDADIVLLLIDAERGIRGDADAILE
HCCCCCEEEEEECCCCCCCHHHHHHHHEEECCCCCCCCCEEEEEEECCCCCCCCHHHHHH
RLKDVRQPMALILNKVDRVKHETLLALSAAANEKVPFKRTFMVSALTGSGCKDLLDYLAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEEEEECCCCCHHHHHHHHHH
ALPAGPWYYPEDQISDLPMRQLAAEITREKLYLRLHQELPYSSHIETEKWEEKPDGSVRI
HCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCEEE
DQTIYVERDSQKKIVLGHKGETIRAIGQAARMEIAGILEQKVHLFLFVKVRENWGDDPER
EEEEEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCEEEEEEEEEECCCCCCHHH
YREMGLEFPH
HHHCCCCCCC
>Mature Secondary Structure
MERGMTDIETAETPATHSGFVALIGAPNAGKSTLVNQLVGAKVSIVTHKVQTTRAIVRGI
CCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCEEEEEEHHHHHHHHHHHHH
ATHDNAQIVFVDTPGIFKPKRRLDTAMVTTAWGGAKDADIVLLLIDAERGIRGDADAILE
HCCCCCEEEEEECCCCCCCHHHHHHHHEEECCCCCCCCCEEEEEEECCCCCCCCHHHHHH
RLKDVRQPMALILNKVDRVKHETLLALSAAANEKVPFKRTFMVSALTGSGCKDLLDYLAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEEEEECCCCCHHHHHHHHHH
ALPAGPWYYPEDQISDLPMRQLAAEITREKLYLRLHQELPYSSHIETEKWEEKPDGSVRI
HCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCEEE
DQTIYVERDSQKKIVLGHKGETIRAIGQAARMEIAGILEQKVHLFLFVKVRENWGDDPER
EEEEEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCEEEEEEEEEECCCCCCHHH
YREMGLEFPH
HHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11214968