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The map label for this gene is cysQ [H]

Identifier: 13476294

GI number: 13476294

Start: 6262364

End: 6263215

Strand: Direct

Name: cysQ [H]

Synonym: mlr7577

Alternate gene names: 13476294

Gene position: 6262364-6263215 (Clockwise)

Preceding gene: 13476293

Following gene: 13476299

Centisome position: 89.0

GC content: 65.61

Gene sequence:

>852_bases
ATGAGCGCGACATTGCCGAAGACCAATATGAAAGCGGCGGCGGCATCTGACGACAGGTCGATGCTCGACATCTTGGAGCG
GCTGGCCCTGGCGGCCGGACGCGAGGTGATGCGCGTTTTCCACGCCGGCTGCGCCGTCGACCGGAAATCAGACGCCTCGC
CGGTGACCGAGGCGGACCGTGAGAGCGAGAAGATCATTCTCTCCGGCCTGCGCGCCGCATTTCCCGAGATTCCCTGCGTG
GCCGAAGAGGAAGCGGCGGCTGGAATCATGCCGACCGATCTCGGCGAGGCCTTCTTCCTCATCGACCCGCTCGACGGCAC
CAAGGAATTCGTCAATCGCCGTACCGACTTCACCGTCAACATCGCGCTTGTCCGCCATGGCGTGCCAGAAGTCGGCGTCG
TCTTCGCGCCGTGCACCGGCCGCTTCTTTTCGGGACGGCCGGGCAGCGCGGAAGCCCTGGAAATCGATGACGACTATCAG
ATCGTCGGCCGCCGGCCGATTTCGGTGAGAGCGGCCGCATCACCGCTGGCCGTGGTTGCCAGCCGCTCCCACAACACACC
GGAAACCGAAGCCTATATTCGCGACCTAGGCGCCGCCGAGATCGTTTCCGTTGGCTCGTCCTTGAAATTCTGTCTTCTCG
CCAGCGCCGAGGCGGATGTCTATCCGCGGTTCGGCCGCACCATGGAATGGGACACCGCGGCGGGCGACGCGGTGCTGCGC
GCGGCGGGCGGCACGACACGTACGCTGGACGGCAAGCCCTTGGCCTACGGCAAACGCGACCAGGCCGACGACGAGGATTT
CGCCAACCCGCATTTCATCGCCAGCGGCAGGGCAGGGGCAATCCCCGCCTGA

Upstream 100 bases:

>100_bases
GTCGATTCGCCTTACCAAGCGCCGGAACACCCGGAGATCCATCTGAAGACGCTCGGCAAATCGGCGGAAGAGATGGTAGA
TGCCCTGGAACATTGGCTGA

Downstream 100 bases:

>100_bases
GAGCGGGTGCCGATTACTCGGCTGCTGCCTGCGCCGAGTTCGAGCCGATATAGTTGCGGATCGTCTCGATGATCCGGTCC
TGGTCGGCTTCGCTGAGATA

Product: pssB protein, exopolysaccharide production

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MSATLPKTNMKAAAASDDRSMLDILERLALAAGREVMRVFHAGCAVDRKSDASPVTEADRESEKIILSGLRAAFPEIPCV
AEEEAAAGIMPTDLGEAFFLIDPLDGTKEFVNRRTDFTVNIALVRHGVPEVGVVFAPCTGRFFSGRPGSAEALEIDDDYQ
IVGRRPISVRAAASPLAVVASRSHNTPETEAYIRDLGAAEIVSVGSSLKFCLLASAEADVYPRFGRTMEWDTAAGDAVLR
AAGGTTRTLDGKPLAYGKRDQADDEDFANPHFIASGRAGAIPA

Sequences:

>Translated_283_residues
MSATLPKTNMKAAAASDDRSMLDILERLALAAGREVMRVFHAGCAVDRKSDASPVTEADRESEKIILSGLRAAFPEIPCV
AEEEAAAGIMPTDLGEAFFLIDPLDGTKEFVNRRTDFTVNIALVRHGVPEVGVVFAPCTGRFFSGRPGSAEALEIDDDYQ
IVGRRPISVRAAASPLAVVASRSHNTPETEAYIRDLGAAEIVSVGSSLKFCLLASAEADVYPRFGRTMEWDTAAGDAVLR
AAGGTTRTLDGKPLAYGKRDQADDEDFANPHFIASGRAGAIPA
>Mature_282_residues
SATLPKTNMKAAAASDDRSMLDILERLALAAGREVMRVFHAGCAVDRKSDASPVTEADRESEKIILSGLRAAFPEIPCVA
EEEAAAGIMPTDLGEAFFLIDPLDGTKEFVNRRTDFTVNIALVRHGVPEVGVVFAPCTGRFFSGRPGSAEALEIDDDYQI
VGRRPISVRAAASPLAVVASRSHNTPETEAYIRDLGAAEIVSVGSSLKFCLLASAEADVYPRFGRTMEWDTAAGDAVLRA
AGGTTRTLDGKPLAYGKRDQADDEDFANPHFIASGRAGAIPA

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI7657236, Length=238, Percent_Identity=30.672268907563, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI5031789, Length=247, Percent_Identity=28.3400809716599, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI221625487, Length=244, Percent_Identity=28.6885245901639, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1790659, Length=257, Percent_Identity=44.3579766536965, Blast_Score=178, Evalue=3e-46,
Organism=Escherichia coli, GI1788882, Length=241, Percent_Identity=28.2157676348548, Blast_Score=74, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI71995897, Length=236, Percent_Identity=27.9661016949153, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71995905, Length=236, Percent_Identity=27.9661016949153, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6320493, Length=223, Percent_Identity=27.3542600896861, Blast_Score=80, Evalue=5e-16,
Organism=Drosophila melanogaster, GI21357329, Length=213, Percent_Identity=28.169014084507, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24664922, Length=261, Percent_Identity=27.2030651340996, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24641722, Length=232, Percent_Identity=27.5862068965517, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24664926, Length=200, Percent_Identity=25.5, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 30070; Mature: 29939

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS00629 IMP_1 ; PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSATLPKTNMKAAAASDDRSMLDILERLALAAGREVMRVFHAGCAVDRKSDASPVTEADR
CCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
ESEKIILSGLRAAFPEIPCVAEEEAAAGIMPTDLGEAFFLIDPLDGTKEFVNRRTDFTVN
CHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCEEEEEECCCCHHHHHHCCCCEEEE
IALVRHGVPEVGVVFAPCTGRFFSGRPGSAEALEIDDDYQIVGRRPISVRAAASPLAVVA
EEEEECCCCCCCEEEECCCCCCCCCCCCCCCEEEECCCEEEECCCCEEEEECCCCEEEEE
SRSHNTPETEAYIRDLGAAEIVSVGSSLKFCLLASAEADVYPRFGRTMEWDTAAGDAVLR
ECCCCCCHHHHHHHHCCHHHHHHHCCCCEEEEEECCCCCCCCCCCCEECCCCCCCCCEEE
AAGGTTRTLDGKPLAYGKRDQADDEDFANPHFIASGRAGAIPA
ECCCCEEECCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCC
>Mature Secondary Structure 
SATLPKTNMKAAAASDDRSMLDILERLALAAGREVMRVFHAGCAVDRKSDASPVTEADR
CCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
ESEKIILSGLRAAFPEIPCVAEEEAAAGIMPTDLGEAFFLIDPLDGTKEFVNRRTDFTVN
CHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCEEEEEECCCCHHHHHHCCCCEEEE
IALVRHGVPEVGVVFAPCTGRFFSGRPGSAEALEIDDDYQIVGRRPISVRAAASPLAVVA
EEEEECCCCCCCEEEECCCCCCCCCCCCCCCEEEECCCEEEECCCCEEEEECCCCEEEEE
SRSHNTPETEAYIRDLGAAEIVSVGSSLKFCLLASAEADVYPRFGRTMEWDTAAGDAVLR
ECCCCCCHHHHHHHHCCHHHHHHHCCCCEEEEEECCCCCCCCCCCCEECCCCCCCCCEEE
AAGGTTRTLDGKPLAYGKRDQADDEDFANPHFIASGRAGAIPA
ECCCCEEECCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]