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The map label for this gene is 13476267

Identifier: 13476267

GI number: 13476267

Start: 6228263

End: 6229183

Strand: Direct

Name: 13476267

Synonym: mlr7546

Alternate gene names: NA

Gene position: 6228263-6229183 (Clockwise)

Preceding gene: 13476266

Following gene: 13476269

Centisome position: 88.52

GC content: 60.48

Gene sequence:

>921_bases
ATGCCTGCCAATCATCACGCAGCCGACGATCTGACGGATCAACCAACGGACATACCCCAGGTGGGGTTGGCGATCATCAC
CGGCTCGGCAAACTGGGGGCTTGCCTTCCCGGAAGATGTCGAAGTCAACGGCGTGCGTACCTTGCGGCGCGACATGAGTT
TTGAAACGCCTTTCGGTCGCACCGACAACTGGAAGCTGCTCGAGTTCGATTCCTCGATTACCGCCGAAGGCAAACCGAAA
CGTGCCTTGTGCATGTATTCACACGGCAATCCCCGCGACCATATTGATCATTCCTGCCATCGCCGCGCGTTCTGGGTGTT
GATGCAAGCGGGTGTCCGGCAAGTCTTGTCCTGCTCGACCATTGGTGCCGTCAACAAGGCGATCAAGCCCGGCGACATGG
TGGTGAACGCCGATATCATCGAACTGACGCAGACGCCGTTTTCGCTGCTTCCCGGCCGCCAGAGCTTCGACTGCTCGGGC
AAGCAGATCGTATGTCCACGATGCGCGGCGGTTCTGGTCGAAACCGCCCGACGTCATTGGCCAGCCGAATGCCGTATTCA
TGGCATCGAACAGCAGTTGGTCGCCGCTCACTGTTACGGGCCGCGGCTGACGACCCCGGCCGAGGCCCTGGCGTTCCGCA
GCATGGGGGCGGATGTGCTCAACCATTCGATCGCCCCCGAAGCCACCTTGTCGCGAGAGATTAGCGCGTGTTTCGTGCCT
TTGGCGTTCGTGACGGCGGGCTTCAACGACTATATGGACCGCAATCGTCAGAAATTGCTGCAGGAGGACGTGTTGCCGAG
CCTGTCCATGACCGCCTCGCGGGTCGCGCTGGAAACCGCCGCACGACTCCCGGCCAATCCGGAATGCTCTTGCCAAGGTT
TGAAGTCGCCTCAGCCAGAAGAACGGTCCAGCCGGTTCTGA

Upstream 100 bases:

>100_bases
ATCCGACAATCGCGGCGATCTCGACATTGTGGACCGCCATCGTCGTGGTCGTCGTCCTGATCGTGACCCTTCGCCAAAAA
TCCTGACCGAGACTGGAAAC

Downstream 100 bases:

>100_bases
GGCAGGGCAATTGCAAGGTCGTGGCGAGGGCTTGGATTAGCCAGCCGGCATGAAAATGCCGTCAATGGCAGGAGCGGCGT
CTGTCGATACCATGCCGCGC

Product: 5'-methylthioadenosine phosphorylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MPANHHAADDLTDQPTDIPQVGLAIITGSANWGLAFPEDVEVNGVRTLRRDMSFETPFGRTDNWKLLEFDSSITAEGKPK
RALCMYSHGNPRDHIDHSCHRRAFWVLMQAGVRQVLSCSTIGAVNKAIKPGDMVVNADIIELTQTPFSLLPGRQSFDCSG
KQIVCPRCAAVLVETARRHWPAECRIHGIEQQLVAAHCYGPRLTTPAEALAFRSMGADVLNHSIAPEATLSREISACFVP
LAFVTAGFNDYMDRNRQKLLQEDVLPSLSMTASRVALETAARLPANPECSCQGLKSPQPEERSSRF

Sequences:

>Translated_306_residues
MPANHHAADDLTDQPTDIPQVGLAIITGSANWGLAFPEDVEVNGVRTLRRDMSFETPFGRTDNWKLLEFDSSITAEGKPK
RALCMYSHGNPRDHIDHSCHRRAFWVLMQAGVRQVLSCSTIGAVNKAIKPGDMVVNADIIELTQTPFSLLPGRQSFDCSG
KQIVCPRCAAVLVETARRHWPAECRIHGIEQQLVAAHCYGPRLTTPAEALAFRSMGADVLNHSIAPEATLSREISACFVP
LAFVTAGFNDYMDRNRQKLLQEDVLPSLSMTASRVALETAARLPANPECSCQGLKSPQPEERSSRF
>Mature_305_residues
PANHHAADDLTDQPTDIPQVGLAIITGSANWGLAFPEDVEVNGVRTLRRDMSFETPFGRTDNWKLLEFDSSITAEGKPKR
ALCMYSHGNPRDHIDHSCHRRAFWVLMQAGVRQVLSCSTIGAVNKAIKPGDMVVNADIIELTQTPFSLLPGRQSFDCSGK
QIVCPRCAAVLVETARRHWPAECRIHGIEQQLVAAHCYGPRLTTPAEALAFRSMGADVLNHSIAPEATLSREISACFVPL
AFVTAGFNDYMDRNRQKLLQEDVLPSLSMTASRVALETAARLPANPECSCQGLKSPQPEERSSRF

Specific function: Unknown

COG id: COG0005

COG function: function code F; Purine nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/MTAP phosphorylase family [H]

Homologues:

Organism=Homo sapiens, GI47132622, Length=268, Percent_Identity=26.865671641791, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010044
- InterPro:   IPR000845
- InterPro:   IPR001369
- InterPro:   IPR018099 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: NA

Molecular weight: Translated: 33664; Mature: 33532

Theoretical pI: Translated: 6.83; Mature: 6.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPANHHAADDLTDQPTDIPQVGLAIITGSANWGLAFPEDVEVNGVRTLRRDMSFETPFGR
CCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCC
TDNWKLLEFDSSITAEGKPKRALCMYSHGNPRDHIDHSCHRRAFWVLMQAGVRQVLSCST
CCCEEEEEECCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGAVNKAIKPGDMVVNADIIELTQTPFSLLPGRQSFDCSGKQIVCPRCAAVLVETARRHW
HHHHHHCCCCCCEEEECHHEEECCCCHHHCCCCCCCCCCCCEEECHHHHHHHHHHHHHCC
PAECRIHGIEQQLVAAHCYGPRLTTPAEALAFRSMGADVLNHSIAPEATLSREISACFVP
CCHHEEECHHHHHHHHHHCCCCCCCHHHHHHHHHHCHHHHHCCCCCCHHHHHHHHHHHHH
LAFVTAGFNDYMDRNRQKLLQEDVLPSLSMTASRVALETAARLPANPECSCQGLKSPQPE
HHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCH
ERSSRF
HHCCCC
>Mature Secondary Structure 
PANHHAADDLTDQPTDIPQVGLAIITGSANWGLAFPEDVEVNGVRTLRRDMSFETPFGR
CCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCC
TDNWKLLEFDSSITAEGKPKRALCMYSHGNPRDHIDHSCHRRAFWVLMQAGVRQVLSCST
CCCEEEEEECCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGAVNKAIKPGDMVVNADIIELTQTPFSLLPGRQSFDCSGKQIVCPRCAAVLVETARRHW
HHHHHHCCCCCCEEEECHHEEECCCCHHHCCCCCCCCCCCCEEECHHHHHHHHHHHHHCC
PAECRIHGIEQQLVAAHCYGPRLTTPAEALAFRSMGADVLNHSIAPEATLSREISACFVP
CCHHEEECHHHHHHHHHHCCCCCCCHHHHHHHHHHCHHHHHCCCCCCHHHHHHHHHHHHH
LAFVTAGFNDYMDRNRQKLLQEDVLPSLSMTASRVALETAARLPANPECSCQGLKSPQPE
HHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCH
ERSSRF
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]