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The map label for this gene is aglR [H]

Identifier: 13476262

GI number: 13476262

Start: 6223249

End: 6224247

Strand: Reverse

Name: aglR [H]

Synonym: mll7541

Alternate gene names: 13476262

Gene position: 6224247-6223249 (Counterclockwise)

Preceding gene: 13476268

Following gene: 13476259

Centisome position: 88.46

GC content: 62.16

Gene sequence:

>999_bases
ATGGCCAATCTAAAACAGATCGCGGCGGAACTTTCCCTTTCGGTGACCACGGTATCGCGCGCTCTGAAGGACGGGCCGGA
GGTGCATCCCTCTACCGTGGCGCGCGTCAAGGAAGTGGCCAAGCGGGTCGGCTATGTCCCGAACCATCACGGCCGGGCGC
TGAAAACCGGACAGACCCTGACGCTGACGGCCGTGCTGCCGATGGAAACACGCGACTACCTGTCGGATCTGGCGAAGCTT
CCCTTGATCGAAGGCATGACGCTAGCGGCGCGGCAAGCGGGCTATAGTCTGTCAATCTATTCCACCACGCCCGACGACGA
TCCCGTCGAAAGCGTGCAGCGGCTGCTTCAGGCGCACAGCGCCGACGGTCTGATCATCACGCGCATGGTCTCGGGCGATC
CGCGCGTCAGGCTGCTGTTGGATCAGGGCATACCGTTCGTCGCGTTTGGAAGAACCGACCTGGGCATCGCCTATCCCTAT
GTCGATATCGACAATGAACAGATCGCCTATGAGGCGACCCGGCGGCTCATGGACAAGGGCTGTCGACGCATTGCTCTACA
ACTTCTCGTGCAGAAGGATCAGGCGAGCGCCACACGTCTCGCCGGCTATCGAAGGGCGATGGCCGAGGCCGGCATCCCGA
TCGACCAGTCCCTGATCGGTGACGGCACGTTCACAATGGAATCGAGCGCGGCCTGGTTCGATCGCCTGCTGGCGTCGTCA
GATCGTCCAACGGGCCTGGCATGCGCCAACGAACTGGGCCTTCTTGGCGCGTTGCACGCTCTCGGCAGACGGGGTCTGGT
GCCGGGCCGTGACGTTCACATCGTCACCCGTGACAATACTCGTCTGGCGCGTTTCCTGCCGGCGAACATTGGCGTTCATT
CCGTGGACATGGCAGATGTCGGGCACAAACTTATCGAGGTCCTCGAGAGCCGGATCGCCAATCCGCTTGGTCCGGTCGCG
ACGATCTTGCTGCAAGGCAGGTTCGAGCCGGCCGAATAG

Upstream 100 bases:

>100_bases
TCAGTTTCGGCGGGCCTGGATTTGACCCTCGGGTCGAATCCGGTAACGTTACGATGCTCAGCAAAATCAGCCGGCGCTTT
CGCAAATCAAGTCGGGCGAC

Downstream 100 bases:

>100_bases
TCCGTTCGCAGACTGAAGCCACGTTTGTGCGGCACGGCGCAAATCCACCTGGCCGCAGGATGTTCTGGACTTCACTCGGC
GGGCGCCGCCCCGACCTGGC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MANLKQIAAELSLSVTTVSRALKDGPEVHPSTVARVKEVAKRVGYVPNHHGRALKTGQTLTLTAVLPMETRDYLSDLAKL
PLIEGMTLAARQAGYSLSIYSTTPDDDPVESVQRLLQAHSADGLIITRMVSGDPRVRLLLDQGIPFVAFGRTDLGIAYPY
VDIDNEQIAYEATRRLMDKGCRRIALQLLVQKDQASATRLAGYRRAMAEAGIPIDQSLIGDGTFTMESSAAWFDRLLASS
DRPTGLACANELGLLGALHALGRRGLVPGRDVHIVTRDNTRLARFLPANIGVHSVDMADVGHKLIEVLESRIANPLGPVA
TILLQGRFEPAE

Sequences:

>Translated_332_residues
MANLKQIAAELSLSVTTVSRALKDGPEVHPSTVARVKEVAKRVGYVPNHHGRALKTGQTLTLTAVLPMETRDYLSDLAKL
PLIEGMTLAARQAGYSLSIYSTTPDDDPVESVQRLLQAHSADGLIITRMVSGDPRVRLLLDQGIPFVAFGRTDLGIAYPY
VDIDNEQIAYEATRRLMDKGCRRIALQLLVQKDQASATRLAGYRRAMAEAGIPIDQSLIGDGTFTMESSAAWFDRLLASS
DRPTGLACANELGLLGALHALGRRGLVPGRDVHIVTRDNTRLARFLPANIGVHSVDMADVGHKLIEVLESRIANPLGPVA
TILLQGRFEPAE
>Mature_331_residues
ANLKQIAAELSLSVTTVSRALKDGPEVHPSTVARVKEVAKRVGYVPNHHGRALKTGQTLTLTAVLPMETRDYLSDLAKLP
LIEGMTLAARQAGYSLSIYSTTPDDDPVESVQRLLQAHSADGLIITRMVSGDPRVRLLLDQGIPFVAFGRTDLGIAYPYV
DIDNEQIAYEATRRLMDKGCRRIALQLLVQKDQASATRLAGYRRAMAEAGIPIDQSLIGDGTFTMESSAAWFDRLLASSD
RPTGLACANELGLLGALHALGRRGLVPGRDVHIVTRDNTRLARFLPANIGVHSVDMADVGHKLIEVLESRIANPLGPVAT
ILLQGRFEPAE

Specific function: Probable regulatory protein for the binding-protein- dependent transport system for alpha-glucosides such as sucrose, maltose and trehalose [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=291, Percent_Identity=28.1786941580756, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1787948, Length=317, Percent_Identity=27.4447949526814, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790194, Length=318, Percent_Identity=26.4150943396226, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1789068, Length=291, Percent_Identity=26.4604810996564, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1789202, Length=292, Percent_Identity=24.3150684931507, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788474, Length=285, Percent_Identity=26.3157894736842, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787580, Length=310, Percent_Identity=21.9354838709677, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787906, Length=268, Percent_Identity=25.3731343283582, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 35973; Mature: 35842

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: PS50932 HTH_LACI_2 ; PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANLKQIAAELSLSVTTVSRALKDGPEVHPSTVARVKEVAKRVGYVPNHHGRALKTGQTL
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEECCCEE
TLTAVLPMETRDYLSDLAKLPLIEGMTLAARQAGYSLSIYSTTPDDDPVESVQRLLQAHS
EEEEEECCCHHHHHHHHHHCCHHCCCHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHCC
ADGLIITRMVSGDPRVRLLLDQGIPFVAFGRTDLGIAYPYVDIDNEQIAYEATRRLMDKG
CCCEEEEEEECCCCCEEEEEECCCCEEEECCCCCCEEECEEECCCCHHHHHHHHHHHHHH
CRRIALQLLVQKDQASATRLAGYRRAMAEAGIPIDQSLIGDGTFTMESSAAWFDRLLASS
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCEEECCHHHHHHHHHHCC
DRPTGLACANELGLLGALHALGRRGLVPGRDVHIVTRDNTRLARFLPANIGVHSVDMADV
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEHHCCCCCCEEECCHHHH
GHKLIEVLESRIANPLGPVATILLQGRFEPAE
HHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ANLKQIAAELSLSVTTVSRALKDGPEVHPSTVARVKEVAKRVGYVPNHHGRALKTGQTL
CCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEECCCEE
TLTAVLPMETRDYLSDLAKLPLIEGMTLAARQAGYSLSIYSTTPDDDPVESVQRLLQAHS
EEEEEECCCHHHHHHHHHHCCHHCCCHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHCC
ADGLIITRMVSGDPRVRLLLDQGIPFVAFGRTDLGIAYPYVDIDNEQIAYEATRRLMDKG
CCCEEEEEEECCCCCEEEEEECCCCEEEECCCCCCEEECEEECCCCHHHHHHHHHHHHHH
CRRIALQLLVQKDQASATRLAGYRRAMAEAGIPIDQSLIGDGTFTMESSAAWFDRLLASS
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCEEECCHHHHHHHHHHCC
DRPTGLACANELGLLGALHALGRRGLVPGRDVHIVTRDNTRLARFLPANIGVHSVDMADV
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEHHCCCCCCEEECCHHHH
GHKLIEVLESRIANPLGPVATILLQGRFEPAE
HHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10400573; 11481430 [H]