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The map label for this gene is ctaG

Identifier: 13476229

GI number: 13476229

Start: 6189177

End: 6189797

Strand: Direct

Name: ctaG

Synonym: mlr7495

Alternate gene names: 13476229

Gene position: 6189177-6189797 (Clockwise)

Preceding gene: 13476228

Following gene: 13476230

Centisome position: 87.96

GC content: 59.9

Gene sequence:

>621_bases
ATGTCCAAAAAGCCGGCCGGCAAGAACAGCAACCGCATCGTCGCGGCGGTGTGCCTTGCCTTCTTCACCGGTATGATCGG
CATGGCCTATGCCGCCGTGCCGCTCTACAAGATGTTCTGCCAGGCGACCGGCTATGGCGGCACGACGCAACGTGTCGAGA
AGCAATATGCCGGCCGCGTGCTCGACCGCGAGATCACCGTGCGCTTCGACGCCAATATTGCCGGCGTGCCGTGGGAATTC
CAGCCGGTCCAGCGCTCGATGACCATGAAGATCGGCGAGACCGTGCAGGCGCATTATCAGGCGACCAACAAGTTCGATCG
CCCCGTCACCGGTCGCGCCACCTTCAACGTGCAGCCGGAACTGGCGGGTCCGTATTTCAACAAGGTCGAGTGTTTCTGCT
TCACCGATACGTCGCTGAAGCCCGGCGAGACGGTGGACATGCCGGTCCTGTTCTATGTGGACCCCGATATCGTGAATGTG
CCGGAACTGAAGGACGTGAAGACGATCACGCTGTCCTACACGATGTTCCCGGTCGAGAAGAACAAGCCGGTTGCCTCTTC
GGAGCCGGTCCAGGGCACCAGCAAGATAATTTCAGATACCGAAGCAAATCTCGGGGGTTGA

Upstream 100 bases:

>100_bases
TCGCGATCGGCGTGGCGCTGGCGGTGCTTGTCGTCATTTTCTACATCGCCACGATCATCAAGTTCGGCCACAATCTGGGC
ACGATGTGATGAGCGTCGAG

Downstream 100 bases:

>100_bases
TATGGCAGACGCGCACGCAAAACATCACGACTATCATCTCGTCGACCCGAGCCCGTGGCCTTTCCTGGGCTCAATCGGCG
CGCTCGTCATGGCCTTTGGC

Product: cytochrome C oxidase assembly protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 205

Protein sequence:

>206_residues
MSKKPAGKNSNRIVAAVCLAFFTGMIGMAYAAVPLYKMFCQATGYGGTTQRVEKQYAGRVLDREITVRFDANIAGVPWEF
QPVQRSMTMKIGETVQAHYQATNKFDRPVTGRATFNVQPELAGPYFNKVECFCFTDTSLKPGETVDMPVLFYVDPDIVNV
PELKDVKTITLSYTMFPVEKNKPVASSEPVQGTSKIISDTEANLGG

Sequences:

>Translated_206_residues
MSKKPAGKNSNRIVAAVCLAFFTGMIGMAYAAVPLYKMFCQATGYGGTTQRVEKQYAGRVLDREITVRFDANIAGVPWEF
QPVQRSMTMKIGETVQAHYQATNKFDRPVTGRATFNVQPELAGPYFNKVECFCFTDTSLKPGETVDMPVLFYVDPDIVNV
PELKDVKTITLSYTMFPVEKNKPVASSEPVQGTSKIISDTEANLGG
>Mature_205_residues
SKKPAGKNSNRIVAAVCLAFFTGMIGMAYAAVPLYKMFCQATGYGGTTQRVEKQYAGRVLDREITVRFDANIAGVPWEFQ
PVQRSMTMKIGETVQAHYQATNKFDRPVTGRATFNVQPELAGPYFNKVECFCFTDTSLKPGETVDMPVLFYVDPDIVNVP
ELKDVKTITLSYTMFPVEKNKPVASSEPVQGTSKIISDTEANLGG

Specific function: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I

COG id: COG3175

COG function: function code O; Cytochrome oxidase assembly factor

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the COX11/CtaG family

Homologues:

Organism=Homo sapiens, GI4758034, Length=176, Percent_Identity=42.6136363636364, Blast_Score=149, Evalue=2e-36,
Organism=Homo sapiens, GI242247061, Length=130, Percent_Identity=38.4615384615385, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI242247057, Length=130, Percent_Identity=38.4615384615385, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71990692, Length=157, Percent_Identity=43.9490445859873, Blast_Score=144, Evalue=4e-35,
Organism=Saccharomyces cerevisiae, GI6325125, Length=175, Percent_Identity=37.1428571428571, Blast_Score=135, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24581944, Length=161, Percent_Identity=47.8260869565217, Blast_Score=157, Evalue=4e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COXZ_RHILO (Q985W8)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_107799.1
- ProteinModelPortal:   Q985W8
- SMR:   Q985W8
- GeneID:   1230454
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mlr7495
- NMPDR:   fig|266835.1.peg.5900
- HOGENOM:   HBG525908
- OMA:   PVSFYID
- ProtClustDB:   PRK05089
- HAMAP:   MF_00155
- InterPro:   IPR007533
- Gene3D:   G3DSA:2.60.370.10
- PANTHER:   PTHR21320
- PIRSF:   PIRSF005413

Pfam domain/function: PF04442 CtaG_Cox11; SSF110111 CtaG_Cox11

EC number: NA

Molecular weight: Translated: 22701; Mature: 22570

Theoretical pI: Translated: 8.29; Mature: 8.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x17b536f8)-;

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKPAGKNSNRIVAAVCLAFFTGMIGMAYAAVPLYKMFCQATGYGGTTQRVEKQYAGRV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCC
LDREITVRFDANIAGVPWEFQPVQRSMTMKIGETVQAHYQATNKFDRPVTGRATFNVQPE
CCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCC
LAGPYFNKVECFCFTDTSLKPGETVDMPVLFYVDPDIVNVPELKDVKTITLSYTMFPVEK
CCCCCCCCEEEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEEEEEEEEEECC
NKPVASSEPVQGTSKIISDTEANLGG
CCCCCCCCCCCCHHHHHHCCCCCCCH
>Mature Secondary Structure 
SKKPAGKNSNRIVAAVCLAFFTGMIGMAYAAVPLYKMFCQATGYGGTTQRVEKQYAGRV
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCC
LDREITVRFDANIAGVPWEFQPVQRSMTMKIGETVQAHYQATNKFDRPVTGRATFNVQPE
CCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCC
LAGPYFNKVECFCFTDTSLKPGETVDMPVLFYVDPDIVNVPELKDVKTITLSYTMFPVEK
CCCCCCCCEEEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEEEEEEEEEECC
NKPVASSEPVQGTSKIISDTEANLGG
CCCCCCCCCCCCHHHHHHCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11214968