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The map label for this gene is ubiA [H]

Identifier: 13476189

GI number: 13476189

Start: 6151044

End: 6152027

Strand: Reverse

Name: ubiA [H]

Synonym: mll7442

Alternate gene names: 13476189

Gene position: 6152027-6151044 (Counterclockwise)

Preceding gene: 13476190

Following gene: 13476185

Centisome position: 87.44

GC content: 64.94

Gene sequence:

>984_bases
ATGGAACCTATCCAGTCGAAAGCCGCCCAGGGCCGTGTTGCCGATGCACCGAACGGCCATTGGGTCTACCGCGTCCTGCC
GCGCTCGGTTTGGCCCTACGCGCAGCTCGCGCGATGGGACAGGCCGATCGGCTGGCAGTTGCTTTTGTGGCCATGCTGGT
GGTCGGCGGCGCTCGCGGCAAGCGCCTATCCGCGCCCCGGCGACCCGCTGCTCTCACTGCTGCCTGCGCCGTTGTATCTC
GTGCTGTTCCTGGTCGGCGCCATTGCCATGCGCGGCGCCGGCTGCACCTACAACGACATCGTCGACGAGAACATCGACAA
CCAGGTCGATCGCACTCGCTCGCGTCCGCTGCCGTCGGGCCAGACCACGCGCCGGCGGGCCTGGCTGTTTCTTGTGCTGC
AGGCCCTGGTCGGCCTTGCCGTGCTCCTGCAGTTTAACAGCTTCGCCATTCTGCTCGGCATCTGCTCGCTGGCGATCGTC
GCCATCTATCCATTCATGAAGCGTATAACCAACTGGCCGCAATTGTTTCTCGGCCTTGCCTTTTCCTGGGGTGCGCTGAT
GGGATGGGCGGTCGAGTTCGGCGATCTCGATGGCCCCGCCATCATGCTCTATATCGGCTCGATCCTGTGGGTGATCGGCT
ACGACACGATCTATGCGCACCAGGACAAGGAAGACGACGCCATTGTCGGCGTGCGCTCGACGGCGCGGCTGTTCGGCGAC
AACACCAAGTCGTGGCTGGCCGGGCTTTACGGCGGCACGCTGATTTGTTTCGCCATCGCCTTCGCCTCGGCGCAGGCGCC
GGTGGTGGCGCTCGCCGGACTGATCGCCGCCGGCGCCCATATGGCACGGCAGATCGCGGTTCTGGATATCAACGATCCGG
ACCAATGCCTGCGGCTGTTCCGGTCGAACAACCAGGTCGGCTGGCTGATCTTCCTCGGCCTGATCGGCGGCGCGCTGTGG
GTGGCGCTGAAGCCGCTGGTATAG

Upstream 100 bases:

>100_bases
GGTTTTCCACGCGCGACATCTTCGCGTCGTGACGGGCTGACGGTCGCTGCTCATCCGCTTGCCGCTTGACGGTTTCCGCG
GCTGCTGCCACTCCATGGAC

Downstream 100 bases:

>100_bases
CGGCTTCAGGCAACTCCCGCGATCGGGGTGTTCAGTCGCGCGAAATGATCTCCTGGCCGTCGATGACCAGCCTGAGACCG
AGGTTGCCGGCCCTGCGGCG

Product: 4-hydroxybenzoate polyprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MEPIQSKAAQGRVADAPNGHWVYRVLPRSVWPYAQLARWDRPIGWQLLLWPCWWSAALAASAYPRPGDPLLSLLPAPLYL
VLFLVGAIAMRGAGCTYNDIVDENIDNQVDRTRSRPLPSGQTTRRRAWLFLVLQALVGLAVLLQFNSFAILLGICSLAIV
AIYPFMKRITNWPQLFLGLAFSWGALMGWAVEFGDLDGPAIMLYIGSILWVIGYDTIYAHQDKEDDAIVGVRSTARLFGD
NTKSWLAGLYGGTLICFAIAFASAQAPVVALAGLIAAGAHMARQIAVLDINDPDQCLRLFRSNNQVGWLIFLGLIGGALW
VALKPLV

Sequences:

>Translated_327_residues
MEPIQSKAAQGRVADAPNGHWVYRVLPRSVWPYAQLARWDRPIGWQLLLWPCWWSAALAASAYPRPGDPLLSLLPAPLYL
VLFLVGAIAMRGAGCTYNDIVDENIDNQVDRTRSRPLPSGQTTRRRAWLFLVLQALVGLAVLLQFNSFAILLGICSLAIV
AIYPFMKRITNWPQLFLGLAFSWGALMGWAVEFGDLDGPAIMLYIGSILWVIGYDTIYAHQDKEDDAIVGVRSTARLFGD
NTKSWLAGLYGGTLICFAIAFASAQAPVVALAGLIAAGAHMARQIAVLDINDPDQCLRLFRSNNQVGWLIFLGLIGGALW
VALKPLV
>Mature_327_residues
MEPIQSKAAQGRVADAPNGHWVYRVLPRSVWPYAQLARWDRPIGWQLLLWPCWWSAALAASAYPRPGDPLLSLLPAPLYL
VLFLVGAIAMRGAGCTYNDIVDENIDNQVDRTRSRPLPSGQTTRRRAWLFLVLQALVGLAVLLQFNSFAILLGICSLAIV
AIYPFMKRITNWPQLFLGLAFSWGALMGWAVEFGDLDGPAIMLYIGSILWVIGYDTIYAHQDKEDDAIVGVRSTARLFGD
NTKSWLAGLYGGTLICFAIAFASAQAPVVALAGLIAAGAHMARQIAVLDINDPDQCLRLFRSNNQVGWLIFLGLIGGALW
VALKPLV

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=296, Percent_Identity=44.9324324324324, Blast_Score=239, Evalue=3e-63,
Organism=Escherichia coli, GI1790473, Length=282, Percent_Identity=36.8794326241135, Blast_Score=158, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI17553718, Length=295, Percent_Identity=41.6949152542373, Blast_Score=202, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI32565247, Length=298, Percent_Identity=40.6040268456376, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17553720, Length=354, Percent_Identity=35.3107344632768, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI32565245, Length=152, Percent_Identity=43.421052631579, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI32565243, Length=151, Percent_Identity=43.046357615894, Blast_Score=103, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6324370, Length=293, Percent_Identity=37.8839590443686, Blast_Score=172, Evalue=4e-44,
Organism=Drosophila melanogaster, GI21355567, Length=289, Percent_Identity=49.1349480968858, Blast_Score=259, Evalue=2e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 35904; Mature: 35904

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPIQSKAAQGRVADAPNGHWVYRVLPRSVWPYAQLARWDRPIGWQLLLWPCWWSAALAA
CCCCHHHHHCCCCCCCCCCCEEEEECCCCCCCHHHHHHCCCCCCCEEEEHHHHHHHHHHH
SAYPRPGDPLLSLLPAPLYLVLFLVGAIAMRGAGCTYNDIVDENIDNQVDRTRSRPLPSG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHCCCCCCC
QTTRRRAWLFLVLQALVGLAVLLQFNSFAILLGICSLAIVAIYPFMKRITNWPQLFLGLA
CCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
FSWGALMGWAVEFGDLDGPAIMLYIGSILWVIGYDTIYAHQDKEDDAIVGVRSTARLFGD
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCCCCEEEEHHHHHHHHCC
NTKSWLAGLYGGTLICFAIAFASAQAPVVALAGLIAAGAHMARQIAVLDINDPDQCLRLF
CHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHH
RSNNQVGWLIFLGLIGGALWVALKPLV
HCCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEPIQSKAAQGRVADAPNGHWVYRVLPRSVWPYAQLARWDRPIGWQLLLWPCWWSAALAA
CCCCHHHHHCCCCCCCCCCCEEEEECCCCCCCHHHHHHCCCCCCCEEEEHHHHHHHHHHH
SAYPRPGDPLLSLLPAPLYLVLFLVGAIAMRGAGCTYNDIVDENIDNQVDRTRSRPLPSG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHCCCCCCC
QTTRRRAWLFLVLQALVGLAVLLQFNSFAILLGICSLAIVAIYPFMKRITNWPQLFLGLA
CCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
FSWGALMGWAVEFGDLDGPAIMLYIGSILWVIGYDTIYAHQDKEDDAIVGVRSTARLFGD
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCCCCEEEEHHHHHHHHCC
NTKSWLAGLYGGTLICFAIAFASAQAPVVALAGLIAAGAHMARQIAVLDINDPDQCLRLF
CHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHH
RSNNQVGWLIFLGLIGGALWVALKPLV
HCCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA