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The map label for this gene is rnhB

Identifier: 13476167

GI number: 13476167

Start: 6129144

End: 6129839

Strand: Reverse

Name: rnhB

Synonym: mll7416

Alternate gene names: 13476167

Gene position: 6129839-6129144 (Counterclockwise)

Preceding gene: 13476168

Following gene: 13476159

Centisome position: 87.12

GC content: 66.67

Gene sequence:

>696_bases
ATGGCTCGCGCGCGTTCCGATTCTCCGCTTCTCTTCGAAATCGTCGAGAAACCCGATTTCTCCTTCGAGACGAAGGCGAT
GGCTGACGGCCTGTGGCCGGTGGCCGGGATGGACGAGGCCGGCCGCGGCCCTCTGGCTGGACCGGTGGTCGCGGCGGCGG
TGGTGCTCGACCCAGCCAACATTCCCGAAGGCCTCGACGATTCCAAACGGCTCAGCCATTTTCAGCGCGAAGCGTTGTTC
CTGCGCATCCTTGGCTCGGCACAGGCCGTCTCGATGGCCTCGATCAGCGCCGAGGGCATCGACGGCAGCAATATCCTCAA
GGCGAGCCTGGAGGCGATGCGCCGCGCTTTGGTCGGCCTGTCGGTTCGGCCGAAGCTCGCGCTTGCCGACGGACGCGACG
TGCCGCCCGGATTGCCCTGCGATGGCCGCGCGCTGATCAAGGGCGATCAGCGCTCGCAGTCGATCGCCGCCGCTTCCATC
GTCGCCAAGGTTATGCGCGACCGCATGATGTGCGGCTGCGGCAGCCACCACGACCGCTACGGGTTCGAGGTTCATATGGG
CTACGCCACCGCCCGCCACCGCACGGCGATCGAGACGCATGGCCCGGTGGCACGGCTGCACCGCGTTTCGTTCGCGCCGT
TCAGGCTGGGCGGGACTGAGGTGGTGGAAGAAGAAAGTTTGGCCGGGCTTGACTGA

Upstream 100 bases:

>100_bases
GGCCTGCCCCGGCCTGCAGACGGTGCCCTCCCGGTCCGGCGCCCCACCCGACCCGGAGGGACTTGCGGAGAATCGGAGCC
GATGCGAACCTCGCCGCAAC

Downstream 100 bases:

>100_bases
GCCGGACTGATTATCTCTCGGAGATTGACGCAGGCGGCGGTGACAGCCGATCTCCCCCCTGTGGGGAAATGTCCGGCAGG
ACAGAGGTGGGCGCTGTCCC

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HII

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MARARSDSPLLFEIVEKPDFSFETKAMADGLWPVAGMDEAGRGPLAGPVVAAAVVLDPANIPEGLDDSKRLSHFQREALF
LRILGSAQAVSMASISAEGIDGSNILKASLEAMRRALVGLSVRPKLALADGRDVPPGLPCDGRALIKGDQRSQSIAAASI
VAKVMRDRMMCGCGSHHDRYGFEVHMGYATARHRTAIETHGPVARLHRVSFAPFRLGGTEVVEEESLAGLD

Sequences:

>Translated_231_residues
MARARSDSPLLFEIVEKPDFSFETKAMADGLWPVAGMDEAGRGPLAGPVVAAAVVLDPANIPEGLDDSKRLSHFQREALF
LRILGSAQAVSMASISAEGIDGSNILKASLEAMRRALVGLSVRPKLALADGRDVPPGLPCDGRALIKGDQRSQSIAAASI
VAKVMRDRMMCGCGSHHDRYGFEVHMGYATARHRTAIETHGPVARLHRVSFAPFRLGGTEVVEEESLAGLD
>Mature_230_residues
ARARSDSPLLFEIVEKPDFSFETKAMADGLWPVAGMDEAGRGPLAGPVVAAAVVLDPANIPEGLDDSKRLSHFQREALFL
RILGSAQAVSMASISAEGIDGSNILKASLEAMRRALVGLSVRPKLALADGRDVPPGLPCDGRALIKGDQRSQSIAAASIV
AKVMRDRMMCGCGSHHDRYGFEVHMGYATARHRTAIETHGPVARLHRVSFAPFRLGGTEVVEEESLAGLD

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family

Homologues:

Organism=Escherichia coli, GI1786380, Length=193, Percent_Identity=44.559585492228, Blast_Score=140, Evalue=8e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH2_RHILO (Q986D0)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_107737.1
- ProteinModelPortal:   Q986D0
- SMR:   Q986D0
- GeneID:   1230392
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll7416
- NMPDR:   fig|266835.1.peg.5838
- HOGENOM:   HBG584843
- OMA:   RLGPTPI
- ProtClustDB:   PRK00015
- BRENDA:   3.1.26.4
- GO:   GO:0005737
- HAMAP:   MF_00052_B
- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337
- PANTHER:   PTHR10954

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 24626; Mature: 24494

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARARSDSPLLFEIVEKPDFSFETKAMADGLWPVAGMDEAGRGPLAGPVVAAAVVLDPAN
CCCCCCCCCEEEEEECCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCC
IPEGLDDSKRLSHFQREALFLRILGSAQAVSMASISAEGIDGSNILKASLEAMRRALVGL
CCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCC
SVRPKLALADGRDVPPGLPCDGRALIKGDQRSQSIAAASIVAKVMRDRMMCGCGSHHDRY
CCCCCEEECCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GFEVHMGYATARHRTAIETHGPVARLHRVSFAPFRLGGTEVVEEESLAGLD
CEEEEECCHHHHHCCHHHCCCHHHHHHHCCCCCEECCCHHHHHHHHHCCCC
>Mature Secondary Structure 
ARARSDSPLLFEIVEKPDFSFETKAMADGLWPVAGMDEAGRGPLAGPVVAAAVVLDPAN
CCCCCCCCEEEEEECCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCC
IPEGLDDSKRLSHFQREALFLRILGSAQAVSMASISAEGIDGSNILKASLEAMRRALVGL
CCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCC
SVRPKLALADGRDVPPGLPCDGRALIKGDQRSQSIAAASIVAKVMRDRMMCGCGSHHDRY
CCCCCEEECCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GFEVHMGYATARHRTAIETHGPVARLHRVSFAPFRLGGTEVVEEESLAGLD
CEEEEECCHHHHHCCHHHCCCHHHHHHHCCCCCEECCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968