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The map label for this gene is soxB [H]

Identifier: 13476085

GI number: 13476085

Start: 6045908

End: 6047161

Strand: Reverse

Name: soxB [H]

Synonym: mll7306

Alternate gene names: 13476085

Gene position: 6047161-6045908 (Counterclockwise)

Preceding gene: 13476086

Following gene: 13476084

Centisome position: 85.95

GC content: 64.35

Gene sequence:

>1254_bases
ATGAAATACTCGATCTTCTCGCTCGCCCGCGCCGCCCTTTCCGGCCACAAGAACTGGCAGCGCACCTGGCGCGACGCCAC
GCCGAAGGACCGCTACGACGTGGTGATCATCGGCGGCGGCGGCCATGGCCTGGCCACCGCCTGGTTCCTCGCCAGCGAAT
ACGGCATCAGGAACGTCGCCGTGCTGGAAAAGGGCTGGATCGGCTCCGGCAATGCCGGCCGCAACACCACCATCATCCGC
TCCAATTACGGCCTGCCCGGCAATACCGGCTTCTACGAATTGTCGATGAAGCTGTGGGAGCGGATGGAGCAGGACCTCAA
CTACAATGCGATGGTCAGCCAGCGCGGCGTCATCAACCTCTACCATTCCGACGCGCAGCGCGACGCCTATGCGCGGCGCG
GCAACACCATGCGCATCAACGGCATCGATGCCGAGTTGCTCGACCTCGCGGCGGTGAAGAAGATGATGCCGTTCCTGAAT
TTCGACAATGCGCGCTTTCCCGTGCAAGGCGGGCTGTTGCAGCGGCGCGGCGGCACGGCGCGGCACGATGCCGTCGTCTG
GGGCTATGCGCATGCTGCGAGCGAGCTCGGCGTCGACATCATCCAGAATTGCGAGGTGACCGGCTTTGTCAGGGACGCCA
ACGGCAAGGTGACCGGCGTCGAAACCTCGCGCGGCAGGATCGGCGCCGGCAAGGTCGGCATGGCGGTCGCCGGCTCCTCG
TCGCGCGTCGCTGATATGGCGGGCCTGCGCCTGCCGATCGAAAGCCATGTGCTGCAGGCCTTCGTCTCCGAGGCGATCAA
GCCGTTGATTCCCAATGTGATGACCTTCGGCGCCGGCCATTTCTATGTCAGCCAGTCGGACAAGGGCGGCCTTGTCTTCG
GCGGCGATATTGATGGCTACAATTCCTACGCTCAGCGCGGCAATCTGCCTGTGATGGAGGATGTCTGCGAGGGCGGCATG
GCGCTGATGCCGATGATCGGCCGCGTGCGTCTATTGCGCCAGTGGGGCGGCATCATGGACATGTCCATGGACGGCTCGCC
GATCATCGACAAGACGCCGGTCGACGGCCTCTATCTCAACGCCGGCTGGTGCTATGGCGGCTTCAAGGCGACGCCTGGCT
CAGGCTTCGTCTTTGCACATCTTCTGGCGCGCGACACGCCGCATGAGGAGGCTGCACGGTTCCGCCTCGACCGCTTCCGG
ACTGGCGCCATGATCGACGAAAAGGGCCAGGGCGCCCAACCGAACCTGCACTGA

Upstream 100 bases:

>100_bases
GGAATGGAATTCCTATGCTTCGCACTTCACGCAATGGGAGCGCGACCACACGCTGGACATATAACCGTCCTGCCGGTGCG
AGCGACCTCGGAATGAACTG

Downstream 100 bases:

>100_bases
GGACGGCCAGAAAATCATGCGCATTGTCTGTCCCTTCTGCGGCGAACGCGAACTTGGCGAGTTCACCTATCTCGGCGACG
CCAAACCGGTGCGACCCGCC

Product: sarcosine oxidase beta subunit

Products: NA

Alternate protein names: Sarcosine oxidase subunit B [H]

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MKYSIFSLARAALSGHKNWQRTWRDATPKDRYDVVIIGGGGHGLATAWFLASEYGIRNVAVLEKGWIGSGNAGRNTTIIR
SNYGLPGNTGFYELSMKLWERMEQDLNYNAMVSQRGVINLYHSDAQRDAYARRGNTMRINGIDAELLDLAAVKKMMPFLN
FDNARFPVQGGLLQRRGGTARHDAVVWGYAHAASELGVDIIQNCEVTGFVRDANGKVTGVETSRGRIGAGKVGMAVAGSS
SRVADMAGLRLPIESHVLQAFVSEAIKPLIPNVMTFGAGHFYVSQSDKGGLVFGGDIDGYNSYAQRGNLPVMEDVCEGGM
ALMPMIGRVRLLRQWGGIMDMSMDGSPIIDKTPVDGLYLNAGWCYGGFKATPGSGFVFAHLLARDTPHEEAARFRLDRFR
TGAMIDEKGQGAQPNLH

Sequences:

>Translated_417_residues
MKYSIFSLARAALSGHKNWQRTWRDATPKDRYDVVIIGGGGHGLATAWFLASEYGIRNVAVLEKGWIGSGNAGRNTTIIR
SNYGLPGNTGFYELSMKLWERMEQDLNYNAMVSQRGVINLYHSDAQRDAYARRGNTMRINGIDAELLDLAAVKKMMPFLN
FDNARFPVQGGLLQRRGGTARHDAVVWGYAHAASELGVDIIQNCEVTGFVRDANGKVTGVETSRGRIGAGKVGMAVAGSS
SRVADMAGLRLPIESHVLQAFVSEAIKPLIPNVMTFGAGHFYVSQSDKGGLVFGGDIDGYNSYAQRGNLPVMEDVCEGGM
ALMPMIGRVRLLRQWGGIMDMSMDGSPIIDKTPVDGLYLNAGWCYGGFKATPGSGFVFAHLLARDTPHEEAARFRLDRFR
TGAMIDEKGQGAQPNLH
>Mature_417_residues
MKYSIFSLARAALSGHKNWQRTWRDATPKDRYDVVIIGGGGHGLATAWFLASEYGIRNVAVLEKGWIGSGNAGRNTTIIR
SNYGLPGNTGFYELSMKLWERMEQDLNYNAMVSQRGVINLYHSDAQRDAYARRGNTMRINGIDAELLDLAAVKKMMPFLN
FDNARFPVQGGLLQRRGGTARHDAVVWGYAHAASELGVDIIQNCEVTGFVRDANGKVTGVETSRGRIGAGKVGMAVAGSS
SRVADMAGLRLPIESHVLQAFVSEAIKPLIPNVMTFGAGHFYVSQSDKGGLVFGGDIDGYNSYAQRGNLPVMEDVCEGGM
ALMPMIGRVRLLRQWGGIMDMSMDGSPIIDKTPVDGLYLNAGWCYGGFKATPGSGFVFAHLLARDTPHEEAARFRLDRFR
TGAMIDEKGQGAQPNLH

Specific function: Catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10- methylenetetrahydrofolate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the soxB family [H]

Homologues:

Organism=Homo sapiens, GI197927446, Length=383, Percent_Identity=23.2375979112272, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI21361378, Length=383, Percent_Identity=23.2375979112272, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI24797151, Length=366, Percent_Identity=23.4972677595628, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI20130091, Length=395, Percent_Identity=24.3037974683544, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR006278 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 45433; Mature: 45433

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYSIFSLARAALSGHKNWQRTWRDATPKDRYDVVIIGGGGHGLATAWFLASEYGIRNVA
CCCHHHHHHHHHHHCCCHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEE
VLEKGWIGSGNAGRNTTIIRSNYGLPGNTGFYELSMKLWERMEQDLNYNAMVSQRGVINL
EEECCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCEEEE
YHSDAQRDAYARRGNTMRINGIDAELLDLAAVKKMMPFLNFDNARFPVQGGLLQRRGGTA
ECCCHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
RHDAVVWGYAHAASELGVDIIQNCEVTGFVRDANGKVTGVETSRGRIGAGKVGMAVAGSS
CCCEEEEEHHHHHHHHCHHHHHCCCEEEEEECCCCEEEEEECCCCCCCCCCCCEEEECCC
SRVADMAGLRLPIESHVLQAFVSEAIKPLIPNVMTFGAGHFYVSQSDKGGLVFGGDIDGY
CCHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCEEEEECCCCCCEEECCCCCCC
NSYAQRGNLPVMEDVCEGGMALMPMIGRVRLLRQWGGIMDMSMDGSPIIDKTPVDGLYLN
HHHHHCCCCCHHHHHHCCCEEHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCEEEE
AGWCYGGFKATPGSGFVFAHLLARDTPHEEAARFRLDRFRTGAMIDEKGQGAQPNLH
CEEEECCEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCEECCCCCCCCCCCC
>Mature Secondary Structure
MKYSIFSLARAALSGHKNWQRTWRDATPKDRYDVVIIGGGGHGLATAWFLASEYGIRNVA
CCCHHHHHHHHHHHCCCHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEE
VLEKGWIGSGNAGRNTTIIRSNYGLPGNTGFYELSMKLWERMEQDLNYNAMVSQRGVINL
EEECCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCEEEE
YHSDAQRDAYARRGNTMRINGIDAELLDLAAVKKMMPFLNFDNARFPVQGGLLQRRGGTA
ECCCHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
RHDAVVWGYAHAASELGVDIIQNCEVTGFVRDANGKVTGVETSRGRIGAGKVGMAVAGSS
CCCEEEEEHHHHHHHHCHHHHHCCCEEEEEECCCCEEEEEECCCCCCCCCCCCEEEECCC
SRVADMAGLRLPIESHVLQAFVSEAIKPLIPNVMTFGAGHFYVSQSDKGGLVFGGDIDGY
CCHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCEEEEECCCCCCEEECCCCCCC
NSYAQRGNLPVMEDVCEGGMALMPMIGRVRLLRQWGGIMDMSMDGSPIIDKTPVDGLYLN
HHHHHCCCCCHHHHHHCCCEEHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCEEEE
AGWCYGGFKATPGSGFVFAHLLARDTPHEEAARFRLDRFRTGAMIDEKGQGAQPNLH
CEEEECCEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]