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The map label for this gene is mtnA [H]

Identifier: 13476068

GI number: 13476068

Start: 6019346

End: 6020440

Strand: Reverse

Name: mtnA [H]

Synonym: mll7284

Alternate gene names: 13476068

Gene position: 6020440-6019346 (Counterclockwise)

Preceding gene: 13476069

Following gene: 13476066

Centisome position: 85.57

GC content: 67.03

Gene sequence:

>1095_bases
TTGAACGTCGGCGACCGCCACTACCGCACCATCTGGCTGAGCGACGACGGGCGTTCGGTCGAGATCATCGACCAGCGCTG
GCTGCCGCATGATTTCCGCATCGAGACGATCGGCACGGTTGCCGGAATTGCGACCGCCATCCGCGACATGTGGGTGCGCG
GCGCGCCGCTGATCGGCGTCACCGCGGCCTACGGCGTCGCCATGCAGATGGCGGATGATCCGTCCGACGCAGCGCTCGAT
GGCGTGTGGGAGACACTGCACGAGACGCGCCCGACGGCGATCAATCTGCGCTGGGCGCTGGATGAGATGCGGCGCTTCCT
CAAGCCGCTGCCTTCAGAACAACGCGCCGCGGCCGCCTACCGGCGCGCCGGTGAGATCGCCGACGAGGATGTTGGGCTGA
ACCGCGCCATCGGCGAGAACGGTCTTGCCATCATCAAGGCGATCGCGGCGCGCAAGCAGCCGGGTGAGACGGTCAATATC
CTCACCCATTGCAATGCCGGCTGGCTGGCGACCGTCGATTACGGCACCGCCACCGCGCCGATCTATCTGGCAACGGAAGC
GGGCATCCCGGTCCATGTCTATGTCGACGAAACGCGGCCGCGCAACCAGGGCGCCCAGCTCACCGCCTGGGAGATGGCCG
GCCACGGCGTGCCGCACACGCTGATCGTCGACAATGCCGGCGGCCATCTGATGCAGCGTGGCGCGATCGACATGGTCATC
GTCGGCACCGACCGCACCACTGCCGACGGCGATGTCTGCAACAAGATCGGCACTTATTTGAAGGCGCTCGCCGCCGCCGA
CAATGACGTGCCGTTCTATGTCGCGCTGCCCTCGCCGACCATCGACTGGACGGTGCATGACGGGCTCGAGGAGATCCCTA
TCGAGCAGCGTTCGGCCGACGAGGTCTCGCTTGTCTGGGGCAAGACCGTCAGCGGCGAGATCGCCCAGGTGCGCATATCG
CCCGAGGCAACGCCGGCGGCGAATCCGGCCTTCGACGTGACCCCGGCGCGACTGGTGACCGGCCTGATCACCGAACGCGG
TGTCGCCAAGGCCTCGCGCGAGGGCCTGAAGGCGATGTTCCCCGAACGGGCATAG

Upstream 100 bases:

>100_bases
CGTTGAAGTTCGGCCGCCACATCGCCGTCAACCGGCGCCAGATACACAGCATCGACGAGGTCAATACCCTGGCCGCGCTG
ATCGAACAGGAGAGCAGCAT

Downstream 100 bases:

>100_bases
CGCCGAAGCCGGCTAGCTAGTACAGCGGCTTGCTCATGTGGCCCGGCGTTGGCCACTTGTCGGTGACGCCGGGCTGCACC
GGACGCTCGAGATAGGTCGA

Product: methylthioribose-1-phosphate isomerase

Products: NA

Alternate protein names: M1Pi; MTR-1-P isomerase; S-methyl-5-thioribose-1-phosphate isomerase [H]

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MNVGDRHYRTIWLSDDGRSVEIIDQRWLPHDFRIETIGTVAGIATAIRDMWVRGAPLIGVTAAYGVAMQMADDPSDAALD
GVWETLHETRPTAINLRWALDEMRRFLKPLPSEQRAAAAYRRAGEIADEDVGLNRAIGENGLAIIKAIAARKQPGETVNI
LTHCNAGWLATVDYGTATAPIYLATEAGIPVHVYVDETRPRNQGAQLTAWEMAGHGVPHTLIVDNAGGHLMQRGAIDMVI
VGTDRTTADGDVCNKIGTYLKALAAADNDVPFYVALPSPTIDWTVHDGLEEIPIEQRSADEVSLVWGKTVSGEIAQVRIS
PEATPAANPAFDVTPARLVTGLITERGVAKASREGLKAMFPERA

Sequences:

>Translated_364_residues
MNVGDRHYRTIWLSDDGRSVEIIDQRWLPHDFRIETIGTVAGIATAIRDMWVRGAPLIGVTAAYGVAMQMADDPSDAALD
GVWETLHETRPTAINLRWALDEMRRFLKPLPSEQRAAAAYRRAGEIADEDVGLNRAIGENGLAIIKAIAARKQPGETVNI
LTHCNAGWLATVDYGTATAPIYLATEAGIPVHVYVDETRPRNQGAQLTAWEMAGHGVPHTLIVDNAGGHLMQRGAIDMVI
VGTDRTTADGDVCNKIGTYLKALAAADNDVPFYVALPSPTIDWTVHDGLEEIPIEQRSADEVSLVWGKTVSGEIAQVRIS
PEATPAANPAFDVTPARLVTGLITERGVAKASREGLKAMFPERA
>Mature_364_residues
MNVGDRHYRTIWLSDDGRSVEIIDQRWLPHDFRIETIGTVAGIATAIRDMWVRGAPLIGVTAAYGVAMQMADDPSDAALD
GVWETLHETRPTAINLRWALDEMRRFLKPLPSEQRAAAAYRRAGEIADEDVGLNRAIGENGLAIIKAIAARKQPGETVNI
LTHCNAGWLATVDYGTATAPIYLATEAGIPVHVYVDETRPRNQGAQLTAWEMAGHGVPHTLIVDNAGGHLMQRGAIDMVI
VGTDRTTADGDVCNKIGTYLKALAAADNDVPFYVALPSPTIDWTVHDGLEEIPIEQRSADEVSLVWGKTVSGEIAQVRIS
PEATPAANPAFDVTPARLVTGLITERGVAKASREGLKAMFPERA

Specific function: Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) [H]

COG id: COG0182

COG function: function code J; Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily [H]

Homologues:

Organism=Homo sapiens, GI72534748, Length=345, Percent_Identity=37.3913043478261, Blast_Score=179, Evalue=4e-45,
Organism=Homo sapiens, GI23943880, Length=160, Percent_Identity=44.375, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17557462, Length=349, Percent_Identity=34.0974212034384, Blast_Score=170, Evalue=8e-43,
Organism=Saccharomyces cerevisiae, GI6325375, Length=397, Percent_Identity=31.7380352644836, Blast_Score=167, Evalue=3e-42,
Organism=Drosophila melanogaster, GI21357667, Length=351, Percent_Identity=38.7464387464387, Blast_Score=201, Evalue=7e-52,
Organism=Drosophila melanogaster, GI24651647, Length=351, Percent_Identity=38.7464387464387, Blast_Score=201, Evalue=7e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000649
- InterPro:   IPR005251
- InterPro:   IPR011559 [H]

Pfam domain/function: PF01008 IF-2B [H]

EC number: =5.3.1.23 [H]

Molecular weight: Translated: 39382; Mature: 39382

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVGDRHYRTIWLSDDGRSVEIIDQRWLPHDFRIETIGTVAGIATAIRDMWVRGAPLIGV
CCCCCCEEEEEEECCCCCEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCEEEH
TAAYGVAMQMADDPSDAALDGVWETLHETRPTAINLRWALDEMRRFLKPLPSEQRAAAAY
HHHHHEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHCCCCCHHHHHHHH
RRAGEIADEDVGLNRAIGENGLAIIKAIAARKQPGETVNILTHCNAGWLATVDYGTATAP
HHHCCCCCCCCCCCHHCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEECCCCCCC
IYLATEAGIPVHVYVDETRPRNQGAQLTAWEMAGHGVPHTLIVDNAGGHLMQRGAIDMVI
EEEEECCCCEEEEEEECCCCCCCCCEEEEEECCCCCCCEEEEEECCCCCEEECCCEEEEE
VGTDRTTADGDVCNKIGTYLKALAAADNDVPFYVALPSPTIDWTVHDGLEEIPIEQRSAD
EECCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEECCCHHHCCCCCCCCC
EVSLVWGKTVSGEIAQVRISPEATPAANPAFDVTPARLVTGLITERGVAKASREGLKAMF
CEEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHC
PERA
CCCC
>Mature Secondary Structure
MNVGDRHYRTIWLSDDGRSVEIIDQRWLPHDFRIETIGTVAGIATAIRDMWVRGAPLIGV
CCCCCCEEEEEEECCCCCEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCEEEH
TAAYGVAMQMADDPSDAALDGVWETLHETRPTAINLRWALDEMRRFLKPLPSEQRAAAAY
HHHHHEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHCCCCCHHHHHHHH
RRAGEIADEDVGLNRAIGENGLAIIKAIAARKQPGETVNILTHCNAGWLATVDYGTATAP
HHHCCCCCCCCCCCHHCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEECCCCCCC
IYLATEAGIPVHVYVDETRPRNQGAQLTAWEMAGHGVPHTLIVDNAGGHLMQRGAIDMVI
EEEEECCCCEEEEEEECCCCCCCCCEEEEEECCCCCCCEEEEEECCCCCEEECCCEEEEE
VGTDRTTADGDVCNKIGTYLKALAAADNDVPFYVALPSPTIDWTVHDGLEEIPIEQRSAD
EECCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEECCCHHHCCCCCCCCC
EVSLVWGKTVSGEIAQVRISPEATPAANPAFDVTPARLVTGLITERGVAKASREGLKAMF
CEEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHC
PERA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA