Click here to switch to the map view.

The map label for this gene is lsrR [H]

Identifier: 13476048

GI number: 13476048

Start: 5998610

End: 5999584

Strand: Direct

Name: lsrR [H]

Synonym: mlr7259

Alternate gene names: 13476048

Gene position: 5998610-5999584 (Clockwise)

Preceding gene: 13476047

Following gene: 13476049

Centisome position: 85.26

GC content: 65.54

Gene sequence:

>975_bases
ATGGTAGGGTTCGGCAACGGCCTCCTGCGCGACGATGAAACCAGCATGGCGACGCGTGCCGCGTGGCTTCACTATGCCGG
CGGCCTGACCCAGTCCGAGGTCGCCAAGCGGCTGGGGCTGACCAGCCTCAAGGCCCATCGCCTCATCACCAAGGCCAACC
AGGAAGGGCTGGTGAAGGTCTATATCGACGGTGAAGTGTCGGAATGCGTCGAGCTCGAGGACGAACTCTCCCGCCGCTAC
GGCCTCGATTATTGCGAGGTGGTTCCTGACTTCGATTCCGAGGATCTGCCGCTCAAGGCGCTCGGCATTGCCGGCGCGCA
GTTCCTCAAGCGCGAGATCGAGCGCGGCGAGGAAGCGCTGATCGGCGTCGGCCATGGCCGCACGCTTGCCGCTTGCGTGG
AATATCTGCCGCGCACCTCGACCGACAAGATCCGCTTCGTCTCGCTGCTGGGCGGCCTGACGCGCAAATTCTCGGCCAAC
CCGCATGACGTTATTCACCGCCTGGCCGAACGGACGGGCGCCGAAGCCTATGTCATGCCAGTGCCGATGTTCGCCAACAC
CGCCGAGGACCGCACCGTCCTGCTCGGCCAGAAGGGCATCAGCGAGGTCTTCGATCTCGCGCGATCCGCTGACCTTCTGT
TCGCCGGCATCGGCACCGCCGAGCGCGAGGCGTCGCTGGTCGCCACCGGCATGATCGAAAAGGGCGAGATGGAGGAGATC
CGCCGCAATGGCGGCGTCGGCGAATTGCTCGGCCATTTCTTCGACGAGGCCGGCAAGGCGGTGGCGACGACCGTTTCCGA
CCGGGCGCTGGCGCTGACGCGTGAGGATATCAGCAGCCGCCGGATCGTCGCCGTCGCCGGCGGCAAGATCAAGGTTCGCG
CCATCAAGTCGGTGCTCGAAGGCCGCTATCTCAAGGGCCTGATAACAGACGAGCGGACGGCGCGATCGCTCGTGGAAGAG
ACGCCGGTCGGGTAG

Upstream 100 bases:

>100_bases
CTTCGGTCGCCATGTCGCGATTTGCACAAGGGGTCGCTTGACACCGATCGTCCATTGTGAAAAATTTTGCAGCAACTGAT
AAAAATATCATAGGGCGGAA

Downstream 100 bases:

>100_bases
CCGGTATCGGTTTCAATTGAAACTACCCTGTGGAGGAGAAGACAAAATGCATGAGAAAGAGAAAGACCTCATTGATGCCT
TCCTGCGCGGACAAGTCGAC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MVGFGNGLLRDDETSMATRAAWLHYAGGLTQSEVAKRLGLTSLKAHRLITKANQEGLVKVYIDGEVSECVELEDELSRRY
GLDYCEVVPDFDSEDLPLKALGIAGAQFLKREIERGEEALIGVGHGRTLAACVEYLPRTSTDKIRFVSLLGGLTRKFSAN
PHDVIHRLAERTGAEAYVMPVPMFANTAEDRTVLLGQKGISEVFDLARSADLLFAGIGTAEREASLVATGMIEKGEMEEI
RRNGGVGELLGHFFDEAGKAVATTVSDRALALTREDISSRRIVAVAGGKIKVRAIKSVLEGRYLKGLITDERTARSLVEE
TPVG

Sequences:

>Translated_324_residues
MVGFGNGLLRDDETSMATRAAWLHYAGGLTQSEVAKRLGLTSLKAHRLITKANQEGLVKVYIDGEVSECVELEDELSRRY
GLDYCEVVPDFDSEDLPLKALGIAGAQFLKREIERGEEALIGVGHGRTLAACVEYLPRTSTDKIRFVSLLGGLTRKFSAN
PHDVIHRLAERTGAEAYVMPVPMFANTAEDRTVLLGQKGISEVFDLARSADLLFAGIGTAEREASLVATGMIEKGEMEEI
RRNGGVGELLGHFFDEAGKAVATTVSDRALALTREDISSRRIVAVAGGKIKVRAIKSVLEGRYLKGLITDERTARSLVEE
TPVG
>Mature_324_residues
MVGFGNGLLRDDETSMATRAAWLHYAGGLTQSEVAKRLGLTSLKAHRLITKANQEGLVKVYIDGEVSECVELEDELSRRY
GLDYCEVVPDFDSEDLPLKALGIAGAQFLKREIERGEEALIGVGHGRTLAACVEYLPRTSTDKIRFVSLLGGLTRKFSAN
PHDVIHRLAERTGAEAYVMPVPMFANTAEDRTVLLGQKGISEVFDLARSADLLFAGIGTAEREASLVATGMIEKGEMEEI
RRNGGVGELLGHFFDEAGKAVATTVSDRALALTREDISSRRIVAVAGGKIKVRAIKSVLEGRYLKGLITDERTARSLVEE
TPVG

Specific function: In the absence of autoinducer 2 (AI-2), represses transcription of the lsrACDBFGE operon and its own transcription. In the presence of AI-2, lsrR is inactivated by binding phospho- AI-2, leading to the transcription of the lsr genes [H]

COG id: COG2390

COG function: function code K; Transcriptional regulator, contains sigma factor-related N-terminal domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sorC transcriptional regulatory family [H]

Homologues:

Organism=Escherichia coli, GI1787791, Length=311, Percent_Identity=30.8681672025724, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI87082414, Length=321, Percent_Identity=26.4797507788162, Blast_Score=107, Evalue=7e-25,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04198 Sugar-bind [H]

EC number: NA

Molecular weight: Translated: 35163; Mature: 35163

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGFGNGLLRDDETSMATRAAWLHYAGGLTQSEVAKRLGLTSLKAHRLITKANQEGLVKV
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHCCCCCEEEE
YIDGEVSECVELEDELSRRYGLDYCEVVPDFDSEDLPLKALGIAGAQFLKREIERGEEAL
EECCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEE
IGVGHGRTLAACVEYLPRTSTDKIRFVSLLGGLTRKFSANPHDVIHRLAERTGAEAYVMP
EECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEE
VPMFANTAEDRTVLLGQKGISEVFDLARSADLLFAGIGTAEREASLVATGMIEKGEMEEI
CCHHCCCCCCCEEEECCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCCCCHHHH
RRNGGVGELLGHFFDEAGKAVATTVSDRALALTREDISSRRIVAVAGGKIKVRAIKSVLE
HHCCCHHHHHHHHHHHHCCEEEEECCCHHHEEEHHCCCCCEEEEEECCEEEHHHHHHHHC
GRYLKGLITDERTARSLVEETPVG
CHHHHHHHCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MVGFGNGLLRDDETSMATRAAWLHYAGGLTQSEVAKRLGLTSLKAHRLITKANQEGLVKV
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHCCCCCEEEE
YIDGEVSECVELEDELSRRYGLDYCEVVPDFDSEDLPLKALGIAGAQFLKREIERGEEAL
EECCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEE
IGVGHGRTLAACVEYLPRTSTDKIRFVSLLGGLTRKFSANPHDVIHRLAERTGAEAYVMP
EECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEE
VPMFANTAEDRTVLLGQKGISEVFDLARSADLLFAGIGTAEREASLVATGMIEKGEMEEI
CCHHCCCCCCCEEEECCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCCCCHHHH
RRNGGVGELLGHFFDEAGKAVATTVSDRALALTREDISSRRIVAVAGGKIKVRAIKSVLE
HHCCCHHHHHHHHHHHHCCEEEEECCCHHHEEEHHCCCCCEEEEEECCEEEHHHHHHHHC
GRYLKGLITDERTARSLVEETPVG
CHHHHHHHCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA