Click here to switch to the map view.

The map label for this gene is murA2

Identifier: 13476041

GI number: 13476041

Start: 5990257

End: 5991513

Strand: Reverse

Name: murA2

Synonym: mll7251

Alternate gene names: 13476041

Gene position: 5991513-5990257 (Counterclockwise)

Preceding gene: 13476043

Following gene: 13476040

Centisome position: 85.15

GC content: 67.06

Gene sequence:

>1257_bases
ATGGACAGATTGCGGATCGTTGGCGGACGAAGACTGGAAGGCGCGGTCACCATTTCCGGCGCCAAGAACGCCGCCTTGCC
GCAGATCGCGGCCGCCCTACTCAGCCCCTACCCGCTCGAACTGACCAACCTGCCAGATGTCACCGATGTCGAGAATATGC
TCGGCGTCGTGCGGCTTCATGGCGCCGAGGTGACGCGGTCGGCCCATGCCGCGACGATCGACACCAGTGCCGCCGTTTCG
AAAGAAACGTCTTATGACACGGTGCGCAAAATGCGCGCGACGGTTCTCGTGCTCGCGCCTCTGCTCGCCCGGTTCGGCCA
CGCCCGCGTTTCGCTGCCCGGCGGCTGCGCGATCGGCGCGCGGCCGGTGGACATGCATGTCGCCGCCCTCGCCGCACTCG
GCGCCAAGATCGCCATCGAGAATGGTTTGATCGTCGCCTCGGCGCCGAACGGGCTGACCGGGACGCGCATCGTGCTCAGC
TCGCCGTCCGTCGGGGCAACGGAAACCGCCATGATGGCGGCGACCACGGCCAAGGGCGAAACCGAAATCCTCAACGCAGC
GCGCGAGCCGGAAGTGGCCGATCTCGCCGCTTGCCTCAACGCCATGGGGGCGCGCATCGAAGGCGCCGGCACGCACCGGA
TCTTGATCGCCGGCGACACCGGCTGGCACGCGGCCAGGCACGACATCATTCCGGACCGCATCGAGGCCGGCACCTATGCC
ATCGCCGCGGCGATCACCGGCGGCCAGCTTGAGCTCACCCACGCTCGGCTCGAGCATATGGCCTCGGTGGTGCAATTGCT
GGAGGCCACCGGCGTCAGCGTCTGGCCCGGCGACCGTGGGCTGATCGTCTCGCGCGAGCGGCCGCTCAAGGCCGCCGATC
TCACGACGGAACCCTATCCGGGGTTTCCGACCGACCTGCAGGCGCAGTTCATGGCGCTGATGTGCTGCGCCGAGGGTGCA
TCGCTGTTGCGCGAGACCATCTTCGAGAACCGCTTCATGCATGTGCCGGAGCTGATGCGGCTCGGCGCCAACATCAAGCT
GCAGGGCACCATGGCGCTGGTGCGCGGGGGCGAGAAGCTGCATGGCGCGCAGGTGATGGCCACCGACCTGCGCGCTTCGG
TGTCACTGGTGCTGGCGGCATTGGTCAGCGAAGGCGAGACGATCATTAACCGCGTCTATCATCTCGATCGAGGCTATGAG
CAGTTGGACCGCAAGCTGCGCCTTTGCGGCGCCGACATCGAGCGGCTGAGCGCATGA

Upstream 100 bases:

>100_bases
AACGCAGAATTAATTCTCGGATCGGCCGGGTTCGAGAATCGAATGGCTCTCCCGGAGAGGCCGACCGCCGCCCGGGCTAT
CGCCACGAAAGGGTTCAGCC

Downstream 100 bases:

>100_bases
GCGGCCCGGACTATTTTCTCGGCGTCGATGGCGGCGGTACCGGCTGCCGAGCCCGCATCGAGGATGCGCAAGGCAACTTG
ATGGGACAAGGCCTGTCCGG

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase 2; UDP-N-acetylglucosamine enolpyruvyl transferase 2; EPT 2

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MDRLRIVGGRRLEGAVTISGAKNAALPQIAAALLSPYPLELTNLPDVTDVENMLGVVRLHGAEVTRSAHAATIDTSAAVS
KETSYDTVRKMRATVLVLAPLLARFGHARVSLPGGCAIGARPVDMHVAALAALGAKIAIENGLIVASAPNGLTGTRIVLS
SPSVGATETAMMAATTAKGETEILNAAREPEVADLAACLNAMGARIEGAGTHRILIAGDTGWHAARHDIIPDRIEAGTYA
IAAAITGGQLELTHARLEHMASVVQLLEATGVSVWPGDRGLIVSRERPLKAADLTTEPYPGFPTDLQAQFMALMCCAEGA
SLLRETIFENRFMHVPELMRLGANIKLQGTMALVRGGEKLHGAQVMATDLRASVSLVLAALVSEGETIINRVYHLDRGYE
QLDRKLRLCGADIERLSA

Sequences:

>Translated_418_residues
MDRLRIVGGRRLEGAVTISGAKNAALPQIAAALLSPYPLELTNLPDVTDVENMLGVVRLHGAEVTRSAHAATIDTSAAVS
KETSYDTVRKMRATVLVLAPLLARFGHARVSLPGGCAIGARPVDMHVAALAALGAKIAIENGLIVASAPNGLTGTRIVLS
SPSVGATETAMMAATTAKGETEILNAAREPEVADLAACLNAMGARIEGAGTHRILIAGDTGWHAARHDIIPDRIEAGTYA
IAAAITGGQLELTHARLEHMASVVQLLEATGVSVWPGDRGLIVSRERPLKAADLTTEPYPGFPTDLQAQFMALMCCAEGA
SLLRETIFENRFMHVPELMRLGANIKLQGTMALVRGGEKLHGAQVMATDLRASVSLVLAALVSEGETIINRVYHLDRGYE
QLDRKLRLCGADIERLSA
>Mature_418_residues
MDRLRIVGGRRLEGAVTISGAKNAALPQIAAALLSPYPLELTNLPDVTDVENMLGVVRLHGAEVTRSAHAATIDTSAAVS
KETSYDTVRKMRATVLVLAPLLARFGHARVSLPGGCAIGARPVDMHVAALAALGAKIAIENGLIVASAPNGLTGTRIVLS
SPSVGATETAMMAATTAKGETEILNAAREPEVADLAACLNAMGARIEGAGTHRILIAGDTGWHAARHDIIPDRIEAGTYA
IAAAITGGQLELTHARLEHMASVVQLLEATGVSVWPGDRGLIVSRERPLKAADLTTEPYPGFPTDLQAQFMALMCCAEGA
SLLRETIFENRFMHVPELMRLGANIKLQGTMALVRGGEKLHGAQVMATDLRASVSLVLAALVSEGETIINRVYHLDRGYE
QLDRKLRLCGADIERLSA

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=421, Percent_Identity=48.2185273159145, Blast_Score=380, Evalue=1e-106,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA2_RHILO (Q986Q6)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_107611.1
- ProteinModelPortal:   Q986Q6
- SMR:   Q986Q6
- GeneID:   1230266
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll7251
- NMPDR:   fig|266835.1.peg.5712
- HOGENOM:   HBG482701
- OMA:   ETEILNA
- ProtClustDB:   PRK09369
- BRENDA:   2.5.1.7
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 44096; Mature: 44096

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: ACT_SITE 116-116

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRLRIVGGRRLEGAVTISGAKNAALPQIAAALLSPYPLELTNLPDVTDVENMLGVVRLH
CCCEEEECCCEECCEEEECCCCCCHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHCC
GAEVTRSAHAATIDTSAAVSKETSYDTVRKMRATVLVLAPLLARFGHARVSLPGGCAIGA
CCHHHCCCCCEEECCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCC
RPVDMHVAALAALGAKIAIENGLIVASAPNGLTGTRIVLSSPSVGATETAMMAATTAKGE
CCHHHHHHHHHHHCCCEEEECCEEEEECCCCCCCCEEEEECCCCCCCHHHHHEEECCCCH
TEILNAAREPEVADLAACLNAMGARIEGAGTHRILIAGDTGWHAARHDIIPDRIEAGTYA
HHHHHHCCCCCHHHHHHHHHHHCCEEECCCCEEEEEECCCCCCHHHCCCCCCHHCCCCEE
IAAAITGGQLELTHARLEHMASVVQLLEATGVSVWPGDRGLIVSRERPLKAADLTTEPYP
EEEEEECCEEEEHHHHHHHHHHHHHHHHHCCCEECCCCCCEEEECCCCCCCCCCCCCCCC
GFPTDLQAQFMALMCCAEGASLLRETIFENRFMHVPELMRLGANIKLQGTMALVRGGEKL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCEEEEEEEEEECCCCHH
HGAQVMATDLRASVSLVLAALVSEGETIINRVYHLDRGYEQLDRKLRLCGADIERLSA
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHCC
>Mature Secondary Structure
MDRLRIVGGRRLEGAVTISGAKNAALPQIAAALLSPYPLELTNLPDVTDVENMLGVVRLH
CCCEEEECCCEECCEEEECCCCCCHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHCC
GAEVTRSAHAATIDTSAAVSKETSYDTVRKMRATVLVLAPLLARFGHARVSLPGGCAIGA
CCHHHCCCCCEEECCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCC
RPVDMHVAALAALGAKIAIENGLIVASAPNGLTGTRIVLSSPSVGATETAMMAATTAKGE
CCHHHHHHHHHHHCCCEEEECCEEEEECCCCCCCCEEEEECCCCCCCHHHHHEEECCCCH
TEILNAAREPEVADLAACLNAMGARIEGAGTHRILIAGDTGWHAARHDIIPDRIEAGTYA
HHHHHHCCCCCHHHHHHHHHHHCCEEECCCCEEEEEECCCCCCHHHCCCCCCHHCCCCEE
IAAAITGGQLELTHARLEHMASVVQLLEATGVSVWPGDRGLIVSRERPLKAADLTTEPYP
EEEEEECCEEEEHHHHHHHHHHHHHHHHHCCCEECCCCCCEEEECCCCCCCCCCCCCCCC
GFPTDLQAQFMALMCCAEGASLLRETIFENRFMHVPELMRLGANIKLQGTMALVRGGEKL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCEEEEEEEEEECCCCHH
HGAQVMATDLRASVSLVLAALVSEGETIINRVYHLDRGYEQLDRKLRLCGADIERLSA
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968