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The map label for this gene is pcaQ [H]

Identifier: 13476002

GI number: 13476002

Start: 5949995

End: 5950912

Strand: Reverse

Name: pcaQ [H]

Synonym: mll7205

Alternate gene names: 13476002

Gene position: 5950912-5949995 (Counterclockwise)

Preceding gene: 13476009

Following gene: 13476001

Centisome position: 84.58

GC content: 64.81

Gene sequence:

>918_bases
ATGGCCGAGAGCCGCATCCGCTTTCGTCATCTGCAGGCATTCCTGGAAGTCGCGCGGCAGGGCAGCGTGGCCCGCGCCGC
CGACTTCCTGCATGTCAGCGCACCGGCAGTGACCAAGACGTTGCGTGAGCTGGAAGAGGCGCTCGGTGTCGCCGTTGTCG
AACGTGACGGGCGCGGTATCCGGGTCACAAGGCTTGGCGAGATCTTCCTCAGCCATGCTGGTTCGGCGATCACGGCGTTG
AAGCGCGGCGTCGATTCCGTTCGCCAGGACGGCGCCATCAACCGCCATCCGATCCGCATCGGCGCGCTGCCGACCGTGTC
GGCGAAGGTCATGCCCAAGGCCATGAGCCTGTTCCTCGGAGAAAATACCGGCGCGGCGATCAAGATCGTCACCGGCGAGA
ACGCCGTGCTGCTCGAGCAATTGCGCACCGGCGCGCTCGATCTTGTCGTCGGTCGGCTTGCGGCGCCCGAAAACATGACC
GGCTTCTTCTTCGAGCATCTCTATTCCGAACAGGTGCTATTCGTGGTGCGGGCTGGACATCCGCTGCTCGAGCCGGGAGC
GGATATCTTCGCGCGGCTCGATGAATTCCCGGTGCTGATGCCGACCCGGGAATCCGTCATCCGCCCCTTTGTCGATCGCC
TGTTCATCACCAACGGCATGACGGCGCCGGCGACCGAGATCGAAACCGTCTCGGACTCCTTCGGTCGCTCCTTCATGCGG
CAAAGCAATGCGGTGTGGATCATTTCGGCCGGCGTGGTCGCCAACGAGATCGCCAGCGGCGCCTTCGTAGCGCTGCCGGT
CGACACCGAGGAAACCAAGGGTCCGGTCGGCCTGACGATGCGCACCGACACGGCGCCATCGCCGGCCTTCACCATCCTGC
TGCAGACCATTCGCGAGGCGGCAAGGCCGGGCAAGTGA

Upstream 100 bases:

>100_bases
ATGACACGATTTCGATCCTCCATCTCCACATTGCACAAGGCATTTGGTTCGGTAAAATGATATTTTGCGCCATTTCATTA
ACTCGGGGGTTATCAAATCC

Downstream 100 bases:

>100_bases
GGCGTCAGACTGTTCGGACCGGGCTCCGTCTCCTTCGAGTCCCCTAACCCCAGGGTTAATGAAACACCGCAAAATATCAT
TTTACCGAACCAAAACGCTG

Product: regulatory protein

Products: NA

Alternate protein names: Pca operon transcriptional activator [H]

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MAESRIRFRHLQAFLEVARQGSVARAADFLHVSAPAVTKTLRELEEALGVAVVERDGRGIRVTRLGEIFLSHAGSAITAL
KRGVDSVRQDGAINRHPIRIGALPTVSAKVMPKAMSLFLGENTGAAIKIVTGENAVLLEQLRTGALDLVVGRLAAPENMT
GFFFEHLYSEQVLFVVRAGHPLLEPGADIFARLDEFPVLMPTRESVIRPFVDRLFITNGMTAPATEIETVSDSFGRSFMR
QSNAVWIISAGVVANEIASGAFVALPVDTEETKGPVGLTMRTDTAPSPAFTILLQTIREAARPGK

Sequences:

>Translated_305_residues
MAESRIRFRHLQAFLEVARQGSVARAADFLHVSAPAVTKTLRELEEALGVAVVERDGRGIRVTRLGEIFLSHAGSAITAL
KRGVDSVRQDGAINRHPIRIGALPTVSAKVMPKAMSLFLGENTGAAIKIVTGENAVLLEQLRTGALDLVVGRLAAPENMT
GFFFEHLYSEQVLFVVRAGHPLLEPGADIFARLDEFPVLMPTRESVIRPFVDRLFITNGMTAPATEIETVSDSFGRSFMR
QSNAVWIISAGVVANEIASGAFVALPVDTEETKGPVGLTMRTDTAPSPAFTILLQTIREAARPGK
>Mature_304_residues
AESRIRFRHLQAFLEVARQGSVARAADFLHVSAPAVTKTLRELEEALGVAVVERDGRGIRVTRLGEIFLSHAGSAITALK
RGVDSVRQDGAINRHPIRIGALPTVSAKVMPKAMSLFLGENTGAAIKIVTGENAVLLEQLRTGALDLVVGRLAAPENMTG
FFFEHLYSEQVLFVVRAGHPLLEPGADIFARLDEFPVLMPTRESVIRPFVDRLFITNGMTAPATEIETVSDSFGRSFMRQ
SNAVWIISAGVVANEIASGAFVALPVDTEETKGPVGLTMRTDTAPSPAFTILLQTIREAARPGK

Specific function: Activates transcription of the pcaDCHGB operon for the catabolism of the phenolic compound protocatechuate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081904, Length=297, Percent_Identity=34.006734006734, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI1787601, Length=296, Percent_Identity=26.3513513513513, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI157672245, Length=282, Percent_Identity=27.6595744680851, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1788887, Length=212, Percent_Identity=27.8301886792453, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790399, Length=297, Percent_Identity=24.5791245791246, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786202, Length=232, Percent_Identity=25.4310344827586, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788297, Length=238, Percent_Identity=26.4705882352941, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1789506, Length=169, Percent_Identity=25.4437869822485, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790208, Length=154, Percent_Identity=27.2727272727273, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR012787
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32923; Mature: 32792

Theoretical pI: Translated: 7.96; Mature: 7.96

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAESRIRFRHLQAFLEVARQGSVARAADFLHVSAPAVTKTLRELEEALGVAVVERDGRGI
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCEEEEECCCCEE
RVTRLGEIFLSHAGSAITALKRGVDSVRQDGAINRHPIRIGALPTVSAKVMPKAMSLFLG
EEHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHC
ENTGAAIKIVTGENAVLLEQLRTGALDLVVGRLAAPENMTGFFFEHLYSEQVLFVVRAGH
CCCCCEEEEEECCCHHHHHHHHHCHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEECCC
PLLEPGADIFARLDEFPVLMPTRESVIRPFVDRLFITNGMTAPATEIETVSDSFGRSFMR
CCCCCCHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
QSNAVWIISAGVVANEIASGAFVALPVDTEETKGPVGLTMRTDTAPSPAFTILLQTIREA
CCCCEEEEECCHHHHHHCCCCEEEEECCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHH
ARPGK
HCCCC
>Mature Secondary Structure 
AESRIRFRHLQAFLEVARQGSVARAADFLHVSAPAVTKTLRELEEALGVAVVERDGRGI
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCEEEEECCCCEE
RVTRLGEIFLSHAGSAITALKRGVDSVRQDGAINRHPIRIGALPTVSAKVMPKAMSLFLG
EEHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHC
ENTGAAIKIVTGENAVLLEQLRTGALDLVVGRLAAPENMTGFFFEHLYSEQVLFVVRAGH
CCCCCEEEEEECCCHHHHHHHHHCHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEECCC
PLLEPGADIFARLDEFPVLMPTRESVIRPFVDRLFITNGMTAPATEIETVSDSFGRSFMR
CCCCCCHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
QSNAVWIISAGVVANEIASGAFVALPVDTEETKGPVGLTMRTDTAPSPAFTILLQTIREA
CCCCEEEEECCHHHHHHCCCCEEEEECCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHH
ARPGK
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]