Click here to switch to the map view.

The map label for this gene is livK [C]

Identifier: 13475983

GI number: 13475983

Start: 5930652

End: 5931911

Strand: Direct

Name: livK [C]

Synonym: mlr7182

Alternate gene names: 13475983

Gene position: 5930652-5931911 (Clockwise)

Preceding gene: 13475982

Following gene: 13475985

Centisome position: 84.29

GC content: 63.25

Gene sequence:

>1260_bases
ATGAGAAAGACGATACTCCAACTCACCACCGCGCTTGCTCTCGTCACGATGGCGGGCGCCGCGCAGGCCGCCGACTGCAA
GATCACCGTCGGCCTCGTCATGGAACTGACCGGTCCGGCCGGCGAATATGGCCAGGCCGGCGCCAAGTCGGTCGAAATGG
CTTTTCGCGACATCAACGAGGCCGGCGGCGTGCGCGGCTGCGATCTGGTGACCGATACGCGCGACAGCCAGAGCCAGGGC
AACATCGCCGTCGACGCCGCGACCCAGCTGGTGCAGGTCAAGAAGGTGCCGGTCATCATCGGCGGCATCATCTCGTCGGT
GTCGATCCCGATCCTGACCTCTGTCACAGCACCTGCCAAGATCGTCCAGGTCTCGCCGGCATCCTCTTCGCCGACGCTGA
CCGCGCTCGGCCGCGACGGCAAGACCAACGGCATCTTCTTCCGCACCATCACGTCCGATGCGCTGCAAGGTGTGGCCGCC
GCCAAATACGCCATCGACAAGGGCTTCAAGAGGCTGTCGATCATCCACGTCAATAACGATTTCGGCGTCAACATGGTGGC
CGAATTCTCGCGCGCCTACAAAGCGCTCGGCGGCACCATCGTCTCCGACACGCCTTACAACGAGAAGCAGTCGAGCTATG
CCTCGGAAGTCACGGCGGCGATGGCCGGCGAGCCGGACGGCCTCTATCTCGTCAGCACCCCGGTCGACGGCGCGACCGTT
GCCCGCACCTGGATTTCGCAAGGCGGCGTGCAGAAATTCCTGCTCAATGACGGCATGAACAGCCCTGACTTCATCGAGTC
CGTCGGCGCCGACTATCTGAAGGACGCCTATGGCACGTCGTCGGGAACCAGCCCGACCGCATCGACCGAGTATTTCACCA
AGAACTACAAGGCATTCTCCGGCATCGAACCCTCCAATCCGGCGGCCGACCGTTCCTATGATGCCGGCGCCATCGTCGGG
CTGGCCATCGCCATCGCCGGCTCCGAGGATCCGGCCAAGATCAAGGACGCCATGTACAAGGCAGTCGACCCGGCCGGCAC
ACCGATCTTCGCCGGCAAGGAGGAGTTCGCCAAGGCGCTTGGCCTGATCAAGGACGGCAAGCCGATCCGCTACGAAGGCG
TCATCGGCCCGGTCGCCTTCGACAAATTCGGCGACATCACCGGTCCGTTCAGGCTGTGGAAGATCATCGACGGCAAGGTG
ACCACCGATGGCGAAATGACCACCGACGACGTCAACGCGCTGCAGGCCAAGCTTCAGTAA

Upstream 100 bases:

>100_bases
CGTCGAATGGCGACACCTGCATGAAACCTGGCTGCAGGTGCCGGAACGCTGAACAGGCTCCAGAGATCAATTTAGTGCGA
GTAACGAAAGGGGAACAACA

Downstream 100 bases:

>100_bases
GCAGACACAGTGGCGCCGGCATCAATCGCGTCTTGCCGTGATTGACGCCGGTGTCGCTCACGGCAGGCGATATCGCTTGC
GCGGCAGGCGATCCCGAATA

Product: ABC transporter, amino acid-binding protein

Products: ADP; phosphate; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MRKTILQLTTALALVTMAGAAQAADCKITVGLVMELTGPAGEYGQAGAKSVEMAFRDINEAGGVRGCDLVTDTRDSQSQG
NIAVDAATQLVQVKKVPVIIGGIISSVSIPILTSVTAPAKIVQVSPASSSPTLTALGRDGKTNGIFFRTITSDALQGVAA
AKYAIDKGFKRLSIIHVNNDFGVNMVAEFSRAYKALGGTIVSDTPYNEKQSSYASEVTAAMAGEPDGLYLVSTPVDGATV
ARTWISQGGVQKFLLNDGMNSPDFIESVGADYLKDAYGTSSGTSPTASTEYFTKNYKAFSGIEPSNPAADRSYDAGAIVG
LAIAIAGSEDPAKIKDAMYKAVDPAGTPIFAGKEEFAKALGLIKDGKPIRYEGVIGPVAFDKFGDITGPFRLWKIIDGKV
TTDGEMTTDDVNALQAKLQ

Sequences:

>Translated_419_residues
MRKTILQLTTALALVTMAGAAQAADCKITVGLVMELTGPAGEYGQAGAKSVEMAFRDINEAGGVRGCDLVTDTRDSQSQG
NIAVDAATQLVQVKKVPVIIGGIISSVSIPILTSVTAPAKIVQVSPASSSPTLTALGRDGKTNGIFFRTITSDALQGVAA
AKYAIDKGFKRLSIIHVNNDFGVNMVAEFSRAYKALGGTIVSDTPYNEKQSSYASEVTAAMAGEPDGLYLVSTPVDGATV
ARTWISQGGVQKFLLNDGMNSPDFIESVGADYLKDAYGTSSGTSPTASTEYFTKNYKAFSGIEPSNPAADRSYDAGAIVG
LAIAIAGSEDPAKIKDAMYKAVDPAGTPIFAGKEEFAKALGLIKDGKPIRYEGVIGPVAFDKFGDITGPFRLWKIIDGKV
TTDGEMTTDDVNALQAKLQ
>Mature_419_residues
MRKTILQLTTALALVTMAGAAQAADCKITVGLVMELTGPAGEYGQAGAKSVEMAFRDINEAGGVRGCDLVTDTRDSQSQG
NIAVDAATQLVQVKKVPVIIGGIISSVSIPILTSVTAPAKIVQVSPASSSPTLTALGRDGKTNGIFFRTITSDALQGVAA
AKYAIDKGFKRLSIIHVNNDFGVNMVAEFSRAYKALGGTIVSDTPYNEKQSSYASEVTAAMAGEPDGLYLVSTPVDGATV
ARTWISQGGVQKFLLNDGMNSPDFIESVGADYLKDAYGTSSGTSPTASTEYFTKNYKAFSGIEPSNPAADRSYDAGAIVG
LAIAIAGSEDPAKIKDAMYKAVDPAGTPIFAGKEEFAKALGLIKDGKPIRYEGVIGPVAFDKFGDITGPFRLWKIIDGKV
TTDGEMTTDDVNALQAKLQ

Specific function: Component of an amino-acid transport system (Potential) [H]

COG id: COG0683

COG function: function code E; ABC-type branched-chain amino acid transport systems, periplasmic component

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the leucine-binding protein family [H]

Homologues:

Organism=Escherichia coli, GI48994941, Length=181, Percent_Identity=30.939226519337, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789867, Length=200, Percent_Identity=29, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: 240 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001828
- InterPro:   IPR000709 [H]

Pfam domain/function: PF01094 ANF_receptor [H]

EC number: NA

Molecular weight: Translated: 43740; Mature: 43740

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKTILQLTTALALVTMAGAAQAADCKITVGLVMELTGPAGEYGQAGAKSVEMAFRDINE
CCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHH
AGGVRGCDLVTDTRDSQSQGNIAVDAATQLVQVKKVPVIIGGIISSVSIPILTSVTAPAK
HCCCCCCEEEECCCCCCCCCCEEEHHHHHHHHHHCCCEEEHHHHHHCCCCCEEECCCCEE
IVQVSPASSSPTLTALGRDGKTNGIFFRTITSDALQGVAAAKYAIDKGFKRLSIIHVNND
EEEECCCCCCCEEEEECCCCCCCCEEEEEECHHHHHHHHHHHHHHHCCCCEEEEEEECCC
FGVNMVAEFSRAYKALGGTIVSDTPYNEKQSSYASEVTAAMAGEPDGLYLVSTPVDGATV
CCCHHHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHH
ARTWISQGGVQKFLLNDGMNSPDFIESVGADYLKDAYGTSSGTSPTASTEYFTKNYKAFS
HHHHHHCCCHHHHHHHCCCCCCHHHHHHCHHHHHHHCCCCCCCCCCCCCHHHHHCCCCCC
GIEPSNPAADRSYDAGAIVGLAIAIAGSEDPAKIKDAMYKAVDPAGTPIFAGKEEFAKAL
CCCCCCCCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHCCCCCCCEECCHHHHHHHH
GLIKDGKPIRYEGVIGPVAFDKFGDITGPFRLWKIIDGKVTTDGEMTTDDVNALQAKLQ
HHHCCCCCEEECCEECCHHHHHCCCCCCCEEEEEEECCEEECCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MRKTILQLTTALALVTMAGAAQAADCKITVGLVMELTGPAGEYGQAGAKSVEMAFRDINE
CCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHH
AGGVRGCDLVTDTRDSQSQGNIAVDAATQLVQVKKVPVIIGGIISSVSIPILTSVTAPAK
HCCCCCCEEEECCCCCCCCCCEEEHHHHHHHHHHCCCEEEHHHHHHCCCCCEEECCCCEE
IVQVSPASSSPTLTALGRDGKTNGIFFRTITSDALQGVAAAKYAIDKGFKRLSIIHVNND
EEEECCCCCCCEEEEECCCCCCCCEEEEEECHHHHHHHHHHHHHHHCCCCEEEEEEECCC
FGVNMVAEFSRAYKALGGTIVSDTPYNEKQSSYASEVTAAMAGEPDGLYLVSTPVDGATV
CCCHHHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHH
ARTWISQGGVQKFLLNDGMNSPDFIESVGADYLKDAYGTSSGTSPTASTEYFTKNYKAFS
HHHHHHCCCHHHHHHHCCCCCCHHHHHHCHHHHHHHCCCCCCCCCCCCCHHHHHCCCCCC
GIEPSNPAADRSYDAGAIVGLAIAIAGSEDPAKIKDAMYKAVDPAGTPIFAGKEEFAKAL
CCCCCCCCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHCCCCCCCEECCHHHHHHHH
GLIKDGKPIRYEGVIGPVAFDKFGDITGPFRLWKIIDGKVTTDGEMTTDDVNALQAKLQ
HHHCCCCCEEECCEECCHHHHHCCCCCCCEEEEEEECCEEECCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-leucine [Periplasm]; H2O [C]

Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]