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The map label for this gene is dppA [H]

Identifier: 13475859

GI number: 13475859

Start: 5800157

End: 5801674

Strand: Reverse

Name: dppA [H]

Synonym: mll7034

Alternate gene names: 13475859

Gene position: 5801674-5800157 (Counterclockwise)

Preceding gene: 13475860

Following gene: 13475858

Centisome position: 82.46

GC content: 60.74

Gene sequence:

>1518_bases
ATGCTGCTGGCGGGCGGCGCTGCGGTTGCGGCGGGCAGCATAGTGCTTGGCCGTGCCACCAATGCCGTCGCCGCCACGCC
GGTTTCCGGCGGAACGTTCAAGGCCGCCGGCTGGTCGTCCTCGACCGCCGACACGCTCGATCCGGCAAAGGCGTCGCTGT
CGACCGACTATGTCCGCTGCTGCTCGCTCTACAACCGCCTGACTTTCCTAGACAAGGATGGCGTCACGCAGATGGAACTG
GCTGAAAGCTTCGACAGCAAGGACGCCAAGACCTGGACCGTGAAGCTACGCAAGGGCGTCACCTTCCACGACGGCAAGGA
CCTCACCGCCGACGACGTCGTCTACTCGCTGAAGCGCCATCTCGACAAATCGGTTGGTTCCAAGGTCGCCAAGATCGCTG
CGCAGATGACCGGCTTCAAGGCGGTCGACAAGTCGACCGTGGAGATTACGCTCGCCGACCCTAATGCCGACCTTCCGACC
ATCCTGGCGCTGCACCATTTCATGATCGTCCAGGACGGCACCACGGACTTCTCCAAGGGCAACGGCACCGGCGCCTTCGT
GCTGCAAACGTTCGAGCCGGGCGTGCGGTCAGTCGTCACCAAGAACAAGAACTACTGGAAATCGGGCAAGCCCTATCTCG
ACTCCTTCGAGTTCATCGCCATCAGCGACGACAGCGCCCGCGTCAACGCCCTGCTTTCCGGCGACATCAATTTTGCGGCT
TCGATCAATCCGCGCGCCATGAAGCTCATCGGCGGGCAGCAGGGCTTCGAGTTGTCAAAGACGACCTCGGGCAACTACAC
CGACCTCAACATCCGGCTCGACATGGATCCGGGCAACAAGGCCGACTTCGTGGCTGGCATGAAATATCTCGTCAACCGCG
AGCAGATCGTCAAATCGGCGTTGCGCGGACTTGGCGAGATTGGCAACGACCAGCCTGTCTCCCCGGCAAACATCTTCCAC
AATCCCGACATCAAGCCGAAGGCTTTCGACCCGGACAAGGCGAAGTTCCACTTCCAGAAGTCAGGCTTGCTCGGCCAGTC
CATTCCGGTGATCGCATCCGATGCCGCGACCTCCTCGATCGACATGGCGGTGATCATCCAGGCCGCGGGCGCCGATATCG
GCATGAAGCTGGACGTCCAGCGTGTCCCGTCCGACGGCTATTGGGACAATTACTGGCTCAAGGCGCCAATCCATTTCGGC
AACATCAATCCACGCCCGACGCCGGATATCCTGTTCTCGCTCCTCTACGCTTCCAACGCGCCGTGGAACGAAAGCCAGTA
CAAGTCCGAGAAGTTCGACAAGCTGCTTATCGAGGCGCGCGGCTCGCTCGATCAGGCCAAGCGCAAGGAAATCTACAACC
AGATGCAGGTCATGGTCTCCGAGGAGGCCGGAACCATCATCCCGGCCTACATTTCCAACGTGGATGCCCTCTCCAGCAAG
GTGAAGGGTTTGGAGGCGAACCCGCTCGGTGGCATGATGGGCTACGCAATGGCGGAATATCTCTGGCTCGAAGCCTGA

Upstream 100 bases:

>100_bases
GAATGATATGACCGACAAGATCACGAACTGGACCAGCGCAGACGATGCCATGGTCGAAAATGCCATCCGGCGGGGCGCGA
GCCGCCGCGAACTCCTCAAG

Downstream 100 bases:

>100_bases
GAGGCGCCTGCCAGGGACCGGGCAGCCGGCCCCTGGCACCTATTGCGCAATATGGCTTGGCCGAACGCAACCGCAGGAGC
GCTTCCATGACGTCTGGGGT

Product: ABC transporter, binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 505; Mature: 505

Protein sequence:

>505_residues
MLLAGGAAVAAGSIVLGRATNAVAATPVSGGTFKAAGWSSSTADTLDPAKASLSTDYVRCCSLYNRLTFLDKDGVTQMEL
AESFDSKDAKTWTVKLRKGVTFHDGKDLTADDVVYSLKRHLDKSVGSKVAKIAAQMTGFKAVDKSTVEITLADPNADLPT
ILALHHFMIVQDGTTDFSKGNGTGAFVLQTFEPGVRSVVTKNKNYWKSGKPYLDSFEFIAISDDSARVNALLSGDINFAA
SINPRAMKLIGGQQGFELSKTTSGNYTDLNIRLDMDPGNKADFVAGMKYLVNREQIVKSALRGLGEIGNDQPVSPANIFH
NPDIKPKAFDPDKAKFHFQKSGLLGQSIPVIASDAATSSIDMAVIIQAAGADIGMKLDVQRVPSDGYWDNYWLKAPIHFG
NINPRPTPDILFSLLYASNAPWNESQYKSEKFDKLLIEARGSLDQAKRKEIYNQMQVMVSEEAGTIIPAYISNVDALSSK
VKGLEANPLGGMMGYAMAEYLWLEA

Sequences:

>Translated_505_residues
MLLAGGAAVAAGSIVLGRATNAVAATPVSGGTFKAAGWSSSTADTLDPAKASLSTDYVRCCSLYNRLTFLDKDGVTQMEL
AESFDSKDAKTWTVKLRKGVTFHDGKDLTADDVVYSLKRHLDKSVGSKVAKIAAQMTGFKAVDKSTVEITLADPNADLPT
ILALHHFMIVQDGTTDFSKGNGTGAFVLQTFEPGVRSVVTKNKNYWKSGKPYLDSFEFIAISDDSARVNALLSGDINFAA
SINPRAMKLIGGQQGFELSKTTSGNYTDLNIRLDMDPGNKADFVAGMKYLVNREQIVKSALRGLGEIGNDQPVSPANIFH
NPDIKPKAFDPDKAKFHFQKSGLLGQSIPVIASDAATSSIDMAVIIQAAGADIGMKLDVQRVPSDGYWDNYWLKAPIHFG
NINPRPTPDILFSLLYASNAPWNESQYKSEKFDKLLIEARGSLDQAKRKEIYNQMQVMVSEEAGTIIPAYISNVDALSSK
VKGLEANPLGGMMGYAMAEYLWLEA
>Mature_505_residues
MLLAGGAAVAAGSIVLGRATNAVAATPVSGGTFKAAGWSSSTADTLDPAKASLSTDYVRCCSLYNRLTFLDKDGVTQMEL
AESFDSKDAKTWTVKLRKGVTFHDGKDLTADDVVYSLKRHLDKSVGSKVAKIAAQMTGFKAVDKSTVEITLADPNADLPT
ILALHHFMIVQDGTTDFSKGNGTGAFVLQTFEPGVRSVVTKNKNYWKSGKPYLDSFEFIAISDDSARVNALLSGDINFAA
SINPRAMKLIGGQQGFELSKTTSGNYTDLNIRLDMDPGNKADFVAGMKYLVNREQIVKSALRGLGEIGNDQPVSPANIFH
NPDIKPKAFDPDKAKFHFQKSGLLGQSIPVIASDAATSSIDMAVIIQAAGADIGMKLDVQRVPSDGYWDNYWLKAPIHFG
NINPRPTPDILFSLLYASNAPWNESQYKSEKFDKLLIEARGSLDQAKRKEIYNQMQVMVSEEAGTIIPAYISNVDALSSK
VKGLEANPLGGMMGYAMAEYLWLEA

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=500, Percent_Identity=27.2, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI1787052, Length=501, Percent_Identity=27.1457085828343, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1787762, Length=474, Percent_Identity=24.4725738396624, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1787495, Length=266, Percent_Identity=28.1954887218045, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI87081878, Length=494, Percent_Identity=25.1012145748988, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1787551, Length=534, Percent_Identity=23.9700374531835, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1789397, Length=311, Percent_Identity=26.0450160771704, Blast_Score=79, Evalue=7e-16,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 54567; Mature: 54567

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLAGGAAVAAGSIVLGRATNAVAATPVSGGTFKAAGWSSSTADTLDPAKASLSTDYVRC
CEEECCHHHHHCCEEEECCCCCEEECCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHH
CSLYNRLTFLDKDGVTQMELAESFDSKDAKTWTVKLRKGVTFHDGKDLTADDVVYSLKRH
HHHHHHHEEECCCCCHHHHHHHHCCCCCCEEEEEEEECCCEEECCCCCCHHHHHHHHHHH
LDKSVGSKVAKIAAQMTGFKAVDKSTVEITLADPNADLPTILALHHFMIVQDGTTDFSKG
HHHHHHHHHHHHHHHHHCCEEECCCEEEEEEECCCCCCHHHHHHHEEEEEECCCCCCCCC
NGTGAFVLQTFEPGVRSVVTKNKNYWKSGKPYLDSFEFIAISDDSARVNALLSGDINFAA
CCCEEEEEEECCCCHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEECCCEEEE
SINPRAMKLIGGQQGFELSKTTSGNYTDLNIRLDMDPGNKADFVAGMKYLVNREQIVKSA
CCCCCEEEEECCCCCCEEECCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHCHHHHHHHH
LRGLGEIGNDQPVSPANIFHNPDIKPKAFDPDKAKFHFQKSGLLGQSIPVIASDAATSSI
HHHHHCCCCCCCCCHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEECCCCCCCC
DMAVIIQAAGADIGMKLDVQRVPSDGYWDNYWLKAPIHFGNINPRPTPDILFSLLYASNA
CEEEEEEECCCCCCEEEEEEECCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHCCC
PWNESQYKSEKFDKLLIEARGSLDQAKRKEIYNQMQVMVSEEAGTIIPAYISNVDALSSK
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEEECCCCCEEHHHHCCHHHHHHH
VKGLEANPLGGMMGYAMAEYLWLEA
HCCCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLLAGGAAVAAGSIVLGRATNAVAATPVSGGTFKAAGWSSSTADTLDPAKASLSTDYVRC
CEEECCHHHHHCCEEEECCCCCEEECCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHH
CSLYNRLTFLDKDGVTQMELAESFDSKDAKTWTVKLRKGVTFHDGKDLTADDVVYSLKRH
HHHHHHHEEECCCCCHHHHHHHHCCCCCCEEEEEEEECCCEEECCCCCCHHHHHHHHHHH
LDKSVGSKVAKIAAQMTGFKAVDKSTVEITLADPNADLPTILALHHFMIVQDGTTDFSKG
HHHHHHHHHHHHHHHHHCCEEECCCEEEEEEECCCCCCHHHHHHHEEEEEECCCCCCCCC
NGTGAFVLQTFEPGVRSVVTKNKNYWKSGKPYLDSFEFIAISDDSARVNALLSGDINFAA
CCCEEEEEEECCCCHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEECCCEEEE
SINPRAMKLIGGQQGFELSKTTSGNYTDLNIRLDMDPGNKADFVAGMKYLVNREQIVKSA
CCCCCEEEEECCCCCCEEECCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHCHHHHHHHH
LRGLGEIGNDQPVSPANIFHNPDIKPKAFDPDKAKFHFQKSGLLGQSIPVIASDAATSSI
HHHHHCCCCCCCCCHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEECCCCCCCC
DMAVIIQAAGADIGMKLDVQRVPSDGYWDNYWLKAPIHFGNINPRPTPDILFSLLYASNA
CEEEEEEECCCCCCEEEEEEECCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHCCC
PWNESQYKSEKFDKLLIEARGSLDQAKRKEIYNQMQVMVSEEAGTIIPAYISNVDALSSK
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEEECCCCCEEHHHHCCHHHHHHH
VKGLEANPLGGMMGYAMAEYLWLEA
HCCCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]