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The map label for this gene is 13475851

Identifier: 13475851

GI number: 13475851

Start: 5790892

End: 5792877

Strand: Direct

Name: 13475851

Synonym: mlr7025

Alternate gene names: NA

Gene position: 5790892-5792877 (Clockwise)

Preceding gene: 13475850

Following gene: 13475852

Centisome position: 82.3

GC content: 66.92

Gene sequence:

>1986_bases
ATGTTTGACCGCACAAACCTCCAGGTTCTGGCCAACCATGCCCGCGCGGCCGCCGAGAACATGGCCCATACGCTGCATCG
CACCGCGCACTCCGCCTTCGTCAAGGAGACGCAGGATTTTACGGTGATGCTGATGGATCGGTCGGGAGCGACCTTCGCCG
TGCCGATGGAGCTTGGCGCCACCTGGTATCCGGGGCTTTCCTATCACCGCGCTATCGCGATGGTCGGCGACTACCGGCCA
GGCGACGTTGCCTTCACCAACGATCCTTATTCCGGCCACGTCGCCACGCACGCGCCCGACACGCACCTGTGGAAGCCGGT
CTTCGTCGACGGCGAGATCGTCGCCTGGGCCGGAGGGCATATCCACAACACCGACATGGGCGGGGCGGTGCCGGCTTCGC
TCAGCCGGGCGCTCACCGAAATCCATCAGGAAGGCATCCGCTTTCCGCCGATGAAGCTGGTGCGGGAAGGTGTCTTCGAT
GAGTCGATCCTGCGGATCATGAGTACCAATGTGCGCAAGCCCGACCTCAACATCGGCGACATCAAGGCGCTGGTTGGGGC
GCTCAACACCGGCGAGCGCAAGATTCAGGCGATGGTGCGGAAGTTCGGCAAGGCCGGTTTCATCGAAGGCGTTTCGGCGC
TTCTCGACCACGCGGAGGCGCAAGCGCGCGACGTGCTGCGCGCCATGCCCGACGGCACCTGGGAATTCGCCGACTACGCC
GACGAGGATTCGGTCGAGGCCAATCCATGCCGGCTGAAGCTGAGGCTGACGATCAGGGGCGACGAGGCGATGCTCGACTT
CACCGGCTCCGATCCGCAACTCGGTTCCTCGCTCAACGTGCCTTCGGGCGGCGATCCGCGCCACACCATGCTTTTGGTGG
GCGTCTACTACGTGCTCTATACGCTGAACCCGAAGATCCTGCTCAACACAGGCCTCACCCGGCCGTTCACCTGCATCGCA
CCCACGGGGTCGGTGCTGAATCCGGTCCATCCCGCCGCGGTCGGCATGCGCTCGCTCACCTGCGCCCGGCTGCGGTCGGT
CATCTTCGGCGCCTTCTCGCAAGCGGTGCCGGAGCGCCTGCCCGCGGCTCCGGCTGGCAACAACTGCATCGTCAACGTCA
TGACCACGGACGAGCGCACCAGCCGGACCGTCATCGCGGCGGTGAATCCGGTCGTGGGCGGCGGCGGCGCGATGCCGCAT
CGCGACGGGACCAACGGCTCTGGCGCGGATGCCGCCTATCTCAAGAACACGCCGATCGAGATCACCGAGACCGAGACCCC
CGTCGAATTCGTGAGATACGGGCTCGCCAGGGACAGTGGTGGCGCGGGCCGCTGGCGCGGCGGGCTGGCGACCGAGATGG
CCTTTCGCGTCTTTGCCCCCGACTCCAGGATCACGGCGCGCAACCGCGACCGCAGTTTCTTCCGTCCTTGGGGTGTGCTG
GGCGGCAAGGCCGCCGGCCTCTCGGACATGGTCGTCAATCCGGGGACCGGGCACGAGCGGCGGCTGGGCAATATCGACAC
CGCGGTCCTGCAGCCCGGCGACGTGCTCGAGATCCGCTCCGCCGGAGGCGGTGGGCGCGGCGATCCATATGAACGCGAGC
CCTGGCGGGTCGCGCAGGATGTGCGGCGCGGCTATCTTTCGCCGGGTGCGGCCGAACGCGACTATGGCGTCGTAGTCCGT
GGCGACGAGGTTGACGAGCAGGCAACGGGGCAATTGCGCGCGCATCACGAGCCGGCCAGCAGCCATTTCCATTTCGGTCC
GGAGCGCGAAGGCTACGAGGCGCAGTGGACGCCGGCAGCCTATGACCGGCTCACCGCCATACTGGGGGACTTGCCGATCC
ACTGGCGGTTCTTCGCCAAGACGGAGATCTTCCGCCGCATGAAGGGACGCTCCGGGGCGGAGGGTGTCCAGGCGGCTTTC
GATGCCGTCTGCGAACGCTTCCCCGAACTGCCGCGTCCCCACCCCGTGCGCGAGGCCGCGGAATGA

Upstream 100 bases:

>100_bases
GTGGTCGTTCAGGAAGACACCACCTTCGCCATTCCCGCCGGAGCGCAGGCACGGGTAGACCGCCATCTCAACCTTCTGCT
GACCTTCGCGGAGTGACGCC

Downstream 100 bases:

>100_bases
TCACGGCCGGCCGTATCGTCCGGCTGGCCGAGCGCGACCGGGCGGGGGTGCATTTCTTTTTCGACGGGCAGATCCGTAGG
GCGCTCGAGGGCGACACTGT

Product: hydantoin utilization protein B

Products: ADP; phosphate; N-carbamoylsarcosine

Alternate protein names: NA

Number of amino acids: Translated: 661; Mature: 661

Protein sequence:

>661_residues
MFDRTNLQVLANHARAAAENMAHTLHRTAHSAFVKETQDFTVMLMDRSGATFAVPMELGATWYPGLSYHRAIAMVGDYRP
GDVAFTNDPYSGHVATHAPDTHLWKPVFVDGEIVAWAGGHIHNTDMGGAVPASLSRALTEIHQEGIRFPPMKLVREGVFD
ESILRIMSTNVRKPDLNIGDIKALVGALNTGERKIQAMVRKFGKAGFIEGVSALLDHAEAQARDVLRAMPDGTWEFADYA
DEDSVEANPCRLKLRLTIRGDEAMLDFTGSDPQLGSSLNVPSGGDPRHTMLLVGVYYVLYTLNPKILLNTGLTRPFTCIA
PTGSVLNPVHPAAVGMRSLTCARLRSVIFGAFSQAVPERLPAAPAGNNCIVNVMTTDERTSRTVIAAVNPVVGGGGAMPH
RDGTNGSGADAAYLKNTPIEITETETPVEFVRYGLARDSGGAGRWRGGLATEMAFRVFAPDSRITARNRDRSFFRPWGVL
GGKAAGLSDMVVNPGTGHERRLGNIDTAVLQPGDVLEIRSAGGGGRGDPYEREPWRVAQDVRRGYLSPGAAERDYGVVVR
GDEVDEQATGQLRAHHEPASSHFHFGPEREGYEAQWTPAAYDRLTAILGDLPIHWRFFAKTEIFRRMKGRSGAEGVQAAF
DAVCERFPELPRPHPVREAAE

Sequences:

>Translated_661_residues
MFDRTNLQVLANHARAAAENMAHTLHRTAHSAFVKETQDFTVMLMDRSGATFAVPMELGATWYPGLSYHRAIAMVGDYRP
GDVAFTNDPYSGHVATHAPDTHLWKPVFVDGEIVAWAGGHIHNTDMGGAVPASLSRALTEIHQEGIRFPPMKLVREGVFD
ESILRIMSTNVRKPDLNIGDIKALVGALNTGERKIQAMVRKFGKAGFIEGVSALLDHAEAQARDVLRAMPDGTWEFADYA
DEDSVEANPCRLKLRLTIRGDEAMLDFTGSDPQLGSSLNVPSGGDPRHTMLLVGVYYVLYTLNPKILLNTGLTRPFTCIA
PTGSVLNPVHPAAVGMRSLTCARLRSVIFGAFSQAVPERLPAAPAGNNCIVNVMTTDERTSRTVIAAVNPVVGGGGAMPH
RDGTNGSGADAAYLKNTPIEITETETPVEFVRYGLARDSGGAGRWRGGLATEMAFRVFAPDSRITARNRDRSFFRPWGVL
GGKAAGLSDMVVNPGTGHERRLGNIDTAVLQPGDVLEIRSAGGGGRGDPYEREPWRVAQDVRRGYLSPGAAERDYGVVVR
GDEVDEQATGQLRAHHEPASSHFHFGPEREGYEAQWTPAAYDRLTAILGDLPIHWRFFAKTEIFRRMKGRSGAEGVQAAF
DAVCERFPELPRPHPVREAAE
>Mature_661_residues
MFDRTNLQVLANHARAAAENMAHTLHRTAHSAFVKETQDFTVMLMDRSGATFAVPMELGATWYPGLSYHRAIAMVGDYRP
GDVAFTNDPYSGHVATHAPDTHLWKPVFVDGEIVAWAGGHIHNTDMGGAVPASLSRALTEIHQEGIRFPPMKLVREGVFD
ESILRIMSTNVRKPDLNIGDIKALVGALNTGERKIQAMVRKFGKAGFIEGVSALLDHAEAQARDVLRAMPDGTWEFADYA
DEDSVEANPCRLKLRLTIRGDEAMLDFTGSDPQLGSSLNVPSGGDPRHTMLLVGVYYVLYTLNPKILLNTGLTRPFTCIA
PTGSVLNPVHPAAVGMRSLTCARLRSVIFGAFSQAVPERLPAAPAGNNCIVNVMTTDERTSRTVIAAVNPVVGGGGAMPH
RDGTNGSGADAAYLKNTPIEITETETPVEFVRYGLARDSGGAGRWRGGLATEMAFRVFAPDSRITARNRDRSFFRPWGVL
GGKAAGLSDMVVNPGTGHERRLGNIDTAVLQPGDVLEIRSAGGGGRGDPYEREPWRVAQDVRRGYLSPGAAERDYGVVVR
GDEVDEQATGQLRAHHEPASSHFHFGPEREGYEAQWTPAAYDRLTAILGDLPIHWRFFAKTEIFRRMKGRSGAEGVQAAF
DAVCERFPELPRPHPVREAAE

Specific function: Unknown

COG id: COG0146

COG function: function code EQ; N-methylhydantoinase B/acetone carboxylase, alpha subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

Organism=Homo sapiens, GI48314820, Length=559, Percent_Identity=30.2325581395349, Blast_Score=182, Evalue=8e-46,
Organism=Caenorhabditis elegans, GI133901900, Length=568, Percent_Identity=28.8732394366197, Blast_Score=159, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI133901902, Length=533, Percent_Identity=28.3302063789869, Blast_Score=140, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6322634, Length=560, Percent_Identity=28.0357142857143, Blast_Score=164, Evalue=3e-41,
Organism=Drosophila melanogaster, GI45550492, Length=577, Percent_Identity=25.4766031195841, Blast_Score=136, Evalue=5e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003692 [H]

Pfam domain/function: PF02538 Hydantoinase_B [H]

EC number: 3.5.2.14

Molecular weight: Translated: 71886; Mature: 71886

Theoretical pI: Translated: 6.83; Mature: 6.83

Prosite motif: PS00276 CHANNEL_COLICIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDRTNLQVLANHARAAAENMAHTLHRTAHSAFVKETQDFTVMLMDRSGATFAVPMELGA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEHHCCC
TWYPGLSYHRAIAMVGDYRPGDVAFTNDPYSGHVATHAPDTHLWKPVFVDGEIVAWAGGH
CCCCCCHHHHEEEEECCCCCCCEEECCCCCCCCEECCCCCCCCCCEEEECCEEEEEECCE
IHNTDMGGAVPASLSRALTEIHQEGIRFPPMKLVREGVFDESILRIMSTNVRKPDLNIGD
EECCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHH
IKALVGALNTGERKIQAMVRKFGKAGFIEGVSALLDHAEAQARDVLRAMPDGTWEFADYA
HHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
DEDSVEANPCRLKLRLTIRGDEAMLDFTGSDPQLGSSLNVPSGGDPRHTMLLVGVYYVLY
CCCCCCCCCEEEEEEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
TLNPKILLNTGLTRPFTCIAPTGSVLNPVHPAAVGMRSLTCARLRSVIFGAFSQAVPERL
HCCCCEEEECCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PAAPAGNNCIVNVMTTDERTSRTVIAAVNPVVGGGGAMPHRDGTNGSGADAAYLKNTPIE
CCCCCCCCEEEEEEECCCCCCCEEEEEECCEECCCCCCCCCCCCCCCCCCCCEECCCCEE
ITETETPVEFVRYGLARDSGGAGRWRGGLATEMAFRVFAPDSRITARNRDRSFFRPWGVL
EECCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHEEEEECCCCCCCCCCCCCCCCCCCCCC
GGKAAGLSDMVVNPGTGHERRLGNIDTAVLQPGDVLEIRSAGGGGRGDPYEREPWRVAQD
CCCCCCCCCEEECCCCCCCCCCCCCCHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHH
VRRGYLSPGAAERDYGVVVRGDEVDEQATGQLRAHHEPASSHFHFGPEREGYEAQWTPAA
HHHCCCCCCCCCCCCEEEEECCCCCCHHHCCCEECCCCCCCCCCCCCCCCCCCCCCCHHH
YDRLTAILGDLPIHWRFFAKTEIFRRMKGRSGAEGVQAAFDAVCERFPELPRPHPVREAA
HHHHHHHHCCCCCEEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHCC
E
C
>Mature Secondary Structure
MFDRTNLQVLANHARAAAENMAHTLHRTAHSAFVKETQDFTVMLMDRSGATFAVPMELGA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEHHCCC
TWYPGLSYHRAIAMVGDYRPGDVAFTNDPYSGHVATHAPDTHLWKPVFVDGEIVAWAGGH
CCCCCCHHHHEEEEECCCCCCCEEECCCCCCCCEECCCCCCCCCCEEEECCEEEEEECCE
IHNTDMGGAVPASLSRALTEIHQEGIRFPPMKLVREGVFDESILRIMSTNVRKPDLNIGD
EECCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHH
IKALVGALNTGERKIQAMVRKFGKAGFIEGVSALLDHAEAQARDVLRAMPDGTWEFADYA
HHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
DEDSVEANPCRLKLRLTIRGDEAMLDFTGSDPQLGSSLNVPSGGDPRHTMLLVGVYYVLY
CCCCCCCCCEEEEEEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
TLNPKILLNTGLTRPFTCIAPTGSVLNPVHPAAVGMRSLTCARLRSVIFGAFSQAVPERL
HCCCCEEEECCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PAAPAGNNCIVNVMTTDERTSRTVIAAVNPVVGGGGAMPHRDGTNGSGADAAYLKNTPIE
CCCCCCCCEEEEEEECCCCCCCEEEEEECCEECCCCCCCCCCCCCCCCCCCCEECCCCEE
ITETETPVEFVRYGLARDSGGAGRWRGGLATEMAFRVFAPDSRITARNRDRSFFRPWGVL
EECCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHEEEEECCCCCCCCCCCCCCCCCCCCCC
GGKAAGLSDMVVNPGTGHERRLGNIDTAVLQPGDVLEIRSAGGGGRGDPYEREPWRVAQD
CCCCCCCCCEEECCCCCCCCCCCCCCHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHH
VRRGYLSPGAAERDYGVVVRGDEVDEQATGQLRAHHEPASSHFHFGPEREGYEAQWTPAA
HHHCCCCCCCCCCCCEEEEECCCCCCHHHCCCEECCCCCCCCCCCCCCCCCCCCCCCHHH
YDRLTAILGDLPIHWRFFAKTEIFRRMKGRSGAEGVQAAFDAVCERFPELPRPHPVREAA
HHHHHHHHCCCCCEEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHCC
E
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; N-methylimidazolidine-2,4-dione; H2O

Specific reaction: ATP + N-methylimidazolidine-2,4-dione + 2 H2O = ADP + phosphate + N-carbamoylsarcosine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]