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The map label for this gene is hipA [C]

Identifier: 13475786

GI number: 13475786

Start: 5715623

End: 5716885

Strand: Reverse

Name: hipA [C]

Synonym: mll6953

Alternate gene names: 13475786

Gene position: 5716885-5715623 (Counterclockwise)

Preceding gene: 13475787

Following gene: 13475782

Centisome position: 81.25

GC content: 58.12

Gene sequence:

>1263_bases
ATGCTGCGCGTTTGGGTCGGTAGCAAGCCGGTCGGCGTCCTGGACAGATCCGGCAGGCGTGGTTCGACTTTCGTGTACGA
TGTGAAGGCCGACGACCGTGACGCCGTGTCGCTCACGATGCCCAAGCGGACCGAATCCTGGAATTCGGAGTTCGGGCTCC
TTCCCATTTTCGACATGAACCTCCCTGAGGGGGCACTTGAAGGGAAGATCAGGACGGCCTTCGCGAAGGCATTAGGTCAC
TTCGACGACCTAGACCTGCTGGCCGTTGTCGGCCGGTCGCAGATCGGCCGTATCCGCTTCACTGGCATGGACGAGGAACT
GGTGGAGGATGTCCCGTTCCGAAGCATTGACGACCTGCTGCGCGCCCGTCGGGCGGGTGATCTCTATAACGACCTCCTCG
AAACATATGCAGTCCATTCAGGGGTCGCTGGAGTGCAGCCGAAGGTCCTGGTGCGAGCCAGGGAAGATGATCCGTCGGAC
GGACGCCAGTCGCTGAGCGTGCGCGGCGCTACCCACATCGTCAAAATGTGGGATCCCGACGAGTATCCCGAATTGGCCGC
AAACGAGTTCTTCTGCCTTATGGCAGCTCAACAAGTTGGTCTCGAGGTGCCGGACTTCCGGCTATCCGAGGATGGTCTGG
CTCTCGTGGTCGAGAGATTCGACCTAACGGACGGCTCGTACTCCGGATATGAGGACTTCTGTGCGCTGAACGGCGTAACC
AGCAAGGACAAGTACAACGGAGGGTACGAAACAAAACTCTTCAAGCGGATCAAAGAGTTCGTTTCTCCCGAAAATGCCGT
TGGGTCATTGGAAGTCGCTTTCCGTCTGTTTGTGATTAATTGCGGTATCCGCAATGGCGATGCACACCTGAAGAATTTCG
GCGTCGTTTACAAGGACGCGGAAAGCCCGGTACGGCTGGCACCCGTGTATGATCTCATCACGACAAGGGCCTACATCAAG
AACGACGCAATGGCGCTCACCCTCGACGGCTCCACCGCCTGGCCCGACCGAAAGAAGCTTGACCGTTTGGGCGTTACCCG
CGCGAACCTCCGACCGGGACGCGTAGCGGAGATCGTAGAGCAGACCTGCGACGCGCTCTCAGACGTTTCGGGAAGGGTGA
AGGCCTATTTTGAAGAATCCAGCTTCCCTGAGGTCGGCGAAAAGATGCTTAGGGAATGGCAGGCTGGAGTGGGCTCCCTT
AGCGAGGGAAAGACGATCCACCTGATGGAGGCTTTAGACGCAACATCAGCGAGAAACGACTAA

Upstream 100 bases:

>100_bases
AAAGGCGTGCTCACGCTCATGAACATTGTAGGGCTCGATTTCCGACTGACGACCTTCAACAACAAGCGTCCGACACTCGA
AGACATCATGGAGGAAGACG

Downstream 100 bases:

>100_bases
AATATCAGCCATTTCAGCGATAATTTAGCATAATAGCCAATATTCGAGCTGTTTTGACTGCTCTATAACCCACCGCGGCC
TTCCAGCCCTCGCTCAGGCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MLRVWVGSKPVGVLDRSGRRGSTFVYDVKADDRDAVSLTMPKRTESWNSEFGLLPIFDMNLPEGALEGKIRTAFAKALGH
FDDLDLLAVVGRSQIGRIRFTGMDEELVEDVPFRSIDDLLRARRAGDLYNDLLETYAVHSGVAGVQPKVLVRAREDDPSD
GRQSLSVRGATHIVKMWDPDEYPELAANEFFCLMAAQQVGLEVPDFRLSEDGLALVVERFDLTDGSYSGYEDFCALNGVT
SKDKYNGGYETKLFKRIKEFVSPENAVGSLEVAFRLFVINCGIRNGDAHLKNFGVVYKDAESPVRLAPVYDLITTRAYIK
NDAMALTLDGSTAWPDRKKLDRLGVTRANLRPGRVAEIVEQTCDALSDVSGRVKAYFEESSFPEVGEKMLREWQAGVGSL
SEGKTIHLMEALDATSARND

Sequences:

>Translated_420_residues
MLRVWVGSKPVGVLDRSGRRGSTFVYDVKADDRDAVSLTMPKRTESWNSEFGLLPIFDMNLPEGALEGKIRTAFAKALGH
FDDLDLLAVVGRSQIGRIRFTGMDEELVEDVPFRSIDDLLRARRAGDLYNDLLETYAVHSGVAGVQPKVLVRAREDDPSD
GRQSLSVRGATHIVKMWDPDEYPELAANEFFCLMAAQQVGLEVPDFRLSEDGLALVVERFDLTDGSYSGYEDFCALNGVT
SKDKYNGGYETKLFKRIKEFVSPENAVGSLEVAFRLFVINCGIRNGDAHLKNFGVVYKDAESPVRLAPVYDLITTRAYIK
NDAMALTLDGSTAWPDRKKLDRLGVTRANLRPGRVAEIVEQTCDALSDVSGRVKAYFEESSFPEVGEKMLREWQAGVGSL
SEGKTIHLMEALDATSARND
>Mature_420_residues
MLRVWVGSKPVGVLDRSGRRGSTFVYDVKADDRDAVSLTMPKRTESWNSEFGLLPIFDMNLPEGALEGKIRTAFAKALGH
FDDLDLLAVVGRSQIGRIRFTGMDEELVEDVPFRSIDDLLRARRAGDLYNDLLETYAVHSGVAGVQPKVLVRAREDDPSD
GRQSLSVRGATHIVKMWDPDEYPELAANEFFCLMAAQQVGLEVPDFRLSEDGLALVVERFDLTDGSYSGYEDFCALNGVT
SKDKYNGGYETKLFKRIKEFVSPENAVGSLEVAFRLFVINCGIRNGDAHLKNFGVVYKDAESPVRLAPVYDLITTRAYIK
NDAMALTLDGSTAWPDRKKLDRLGVTRANLRPGRVAEIVEQTCDALSDVSGRVKAYFEESSFPEVGEKMLREWQAGVGSL
SEGKTIHLMEALDATSARND

Specific function: Unbalanced Or Excessive Expression Of Hipa Is Toxic To The Cell. [C]

COG id: COG3550

COG function: function code R; Uncharacterized protein related to capsule biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli hipA, H.influenzae HI_0665 and y4mE [H]

Homologues:

Organism=Escherichia coli, GI1787785, Length=424, Percent_Identity=24.2924528301887, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012893
- InterPro:   IPR012894
- InterPro:   IPR017508 [H]

Pfam domain/function: PF07804 HipA_C; PF07805 HipA_N [H]

EC number: NA

Molecular weight: Translated: 46597; Mature: 46597

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRVWVGSKPVGVLDRSGRRGSTFVYDVKADDRDAVSLTMPKRTESWNSEFGLLPIFDMN
CEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCCEEEEECC
LPEGALEGKIRTAFAKALGHFDDLDLLAVVGRSQIGRIRFTGMDEELVEDVPFRSIDDLL
CCCHHHCCHHHHHHHHHHCCCCCHHHHHHHCCCCCCEEEECCCCHHHHHHCCCCHHHHHH
RARRAGDLYNDLLETYAVHSGVAGVQPKVLVRAREDDPSDGRQSLSVRGATHIVKMWDPD
HHHHCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHEEECCCEEEEEECCCC
EYPELAANEFFCLMAAQQVGLEVPDFRLSEDGLALVVERFDLTDGSYSGYEDFCALNGVT
CCCHHHHCCHHEEEHHHHHCCCCCCCEECCCCEEEEEEEEECCCCCCCCHHHHHHHCCCC
SKDKYNGGYETKLFKRIKEFVSPENAVGSLEVAFRLFVINCGIRNGDAHLKNFGVVYKDA
CCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHEEEEEEEECCCCCCCCHHHHCCEEEECC
ESPVRLAPVYDLITTRAYIKNDAMALTLDGSTAWPDRKKLDRLGVTRANLRPGRVAEIVE
CCCEEEHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHCCEECCCCCCHHHHHHH
QTCDALSDVSGRVKAYFEESSFPEVGEKMLREWQAGVGSLSEGKTIHLMEALDATSARND
HHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHCCCCC
>Mature Secondary Structure
MLRVWVGSKPVGVLDRSGRRGSTFVYDVKADDRDAVSLTMPKRTESWNSEFGLLPIFDMN
CEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCCEEEEECC
LPEGALEGKIRTAFAKALGHFDDLDLLAVVGRSQIGRIRFTGMDEELVEDVPFRSIDDLL
CCCHHHCCHHHHHHHHHHCCCCCHHHHHHHCCCCCCEEEECCCCHHHHHHCCCCHHHHHH
RARRAGDLYNDLLETYAVHSGVAGVQPKVLVRAREDDPSDGRQSLSVRGATHIVKMWDPD
HHHHCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHEEECCCEEEEEECCCC
EYPELAANEFFCLMAAQQVGLEVPDFRLSEDGLALVVERFDLTDGSYSGYEDFCALNGVT
CCCHHHHCCHHEEEHHHHHCCCCCCCEECCCCEEEEEEEEECCCCCCCCHHHHHHHCCCC
SKDKYNGGYETKLFKRIKEFVSPENAVGSLEVAFRLFVINCGIRNGDAHLKNFGVVYKDA
CCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHEEEEEEEECCCCCCCCHHHHCCEEEECC
ESPVRLAPVYDLITTRAYIKNDAMALTLDGSTAWPDRKKLDRLGVTRANLRPGRVAEIVE
CCCEEEHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHCCEECCCCCCHHHHHHH
QTCDALSDVSGRVKAYFEESSFPEVGEKMLREWQAGVGSLSEGKTIHLMEALDATSARND
HHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]