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The map label for this gene is oxyR [H]

Identifier: 13475776

GI number: 13475776

Start: 5704600

End: 5705508

Strand: Reverse

Name: oxyR [H]

Synonym: mll6938

Alternate gene names: 13475776

Gene position: 5705508-5704600 (Counterclockwise)

Preceding gene: 13475778

Following gene: 13475773

Centisome position: 81.09

GC content: 65.46

Gene sequence:

>909_bases
ATGATCGGATTGACAGTTCGCCAGATGCATTATTTCGACGCGCTGGCGCAGACGCTGCATTTCGGCCGTGCGGCAAAACT
GGCCGGCGTCAGCCAGCCGGCACTGTCCTCGCAGATCGCGGAGATGGAGCAACGGCTGAACTGCCGGCTCTTCGAACGCG
GCGGCAAGTCGGTGCGCATGACTGACGAGGCGATCGCGCTTTTGCCGCGCATCGAACGCATCCTCGCCGACATACGCGAC
GTCGAAACGACGGCCAGGCGCGGCCGCACAGCGATGGAGGGACGCTTCCGGCTGGGCATCATTCCGACCGTCGCGCCGTA
TCTCCTGCCACGCGCTTTGCCCGAACTGAAAAAGCATTTCCCGGCCCTGCTGCTCGAATTGCGCGAGGCGGTCACTACCT
CGCTGGTCGATGACATAGCCTCGCGCAAGCTCGACGCCTTTATCGCCGCGCTTCCGCTCGATCATCCAGGCCTGATCGCC
GAGGCGTTGTTTTCGGACCGGTTCTTCCTTGCCGTGCCGGCTGGCGACCCGGCCTTCGCCTCGCCGCCGGTCCCGCCCGA
AAGCCCGGCGCTGGAAAGGCTTATGCTGCTGGAAGAAGGCCATTGCCTGCGCGAACAGGCGCTCGCCGTCTGCGGCAATG
TGCGGCCGGTAGCGATGGCCAGTTATGGCGCCACCAGCCTGACCACGCTGTTGCAGATGGTGGCGCACGGGCTCGGGGTC
ACGCTGATCCCCGAAATGGCGACCGGCCCCGCCGGCACCATCCCCGACCTCAAGATCGTACCGTTCCAGGAGCCGATGCC
GCAGCGCATGATCTGCCTCGCCTGGCGGCGCAACAATGCAAGGCACGGCGAATGTGTCGAACTCGCCAAGATCATTCGCA
GCCTCGGCGCGGCGGTGTTGGCCGCGTGA

Upstream 100 bases:

>100_bases
GGCCGACCGGCGACCGCACCAATCTGGAACGATTCCAGACTAGGCCGCATTGCTGATAAAAACAAATTGCCTTTCCTGTT
CATTTCGATAGGATTTTCTT

Downstream 100 bases:

>100_bases
GAAGCGACCAGCCAGGCGTCACAGAGTCCGGGACCGACAGGTCCACTGCGATTACGAGTTTGCGATCACCGCACACTCCC
AGATGATGACCTAGGAAGCG

Product: transcriptional regulator

Products: NA

Alternate protein names: Morphology and auto-aggregation control protein [H]

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MIGLTVRQMHYFDALAQTLHFGRAAKLAGVSQPALSSQIAEMEQRLNCRLFERGGKSVRMTDEAIALLPRIERILADIRD
VETTARRGRTAMEGRFRLGIIPTVAPYLLPRALPELKKHFPALLLELREAVTTSLVDDIASRKLDAFIAALPLDHPGLIA
EALFSDRFFLAVPAGDPAFASPPVPPESPALERLMLLEEGHCLREQALAVCGNVRPVAMASYGATSLTTLLQMVAHGLGV
TLIPEMATGPAGTIPDLKIVPFQEPMPQRMICLAWRRNNARHGECVELAKIIRSLGAAVLAA

Sequences:

>Translated_302_residues
MIGLTVRQMHYFDALAQTLHFGRAAKLAGVSQPALSSQIAEMEQRLNCRLFERGGKSVRMTDEAIALLPRIERILADIRD
VETTARRGRTAMEGRFRLGIIPTVAPYLLPRALPELKKHFPALLLELREAVTTSLVDDIASRKLDAFIAALPLDHPGLIA
EALFSDRFFLAVPAGDPAFASPPVPPESPALERLMLLEEGHCLREQALAVCGNVRPVAMASYGATSLTTLLQMVAHGLGV
TLIPEMATGPAGTIPDLKIVPFQEPMPQRMICLAWRRNNARHGECVELAKIIRSLGAAVLAA
>Mature_302_residues
MIGLTVRQMHYFDALAQTLHFGRAAKLAGVSQPALSSQIAEMEQRLNCRLFERGGKSVRMTDEAIALLPRIERILADIRD
VETTARRGRTAMEGRFRLGIIPTVAPYLLPRALPELKKHFPALLLELREAVTTSLVDDIASRKLDAFIAALPLDHPGLIA
EALFSDRFFLAVPAGDPAFASPPVPPESPALERLMLLEEGHCLREQALAVCGNVRPVAMASYGATSLTTLLQMVAHGLGV
TLIPEMATGPAGTIPDLKIVPFQEPMPQRMICLAWRRNNARHGECVELAKIIRSLGAAVLAA

Specific function: Hydrogen peroxide sensor. Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS (a regulatory RNA), dps, fur and grxA. OxyR expression is negatively autoregulated by binding to a 43 bp region upstre

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=291, Percent_Identity=36.0824742268041, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI157672245, Length=281, Percent_Identity=28.4697508896797, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1787879, Length=287, Percent_Identity=26.1324041811847, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788887, Length=293, Percent_Identity=24.9146757679181, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI145693105, Length=281, Percent_Identity=25.9786476868327, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1788748, Length=309, Percent_Identity=26.2135922330097, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI2367136, Length=238, Percent_Identity=27.3109243697479, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787601, Length=184, Percent_Identity=23.9130434782609, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87081904, Length=174, Percent_Identity=28.735632183908, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788297, Length=257, Percent_Identity=24.5136186770428, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788481, Length=276, Percent_Identity=22.8260869565217, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32874; Mature: 32874

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGLTVRQMHYFDALAQTLHFGRAAKLAGVSQPALSSQIAEMEQRLNCRLFERGGKSVRM
CCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHCCHHHHCCCCEEEE
TDEAIALLPRIERILADIRDVETTARRGRTAMEGRFRLGIIPTVAPYLLPRALPELKKHF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHH
PALLLELREAVTTSLVDDIASRKLDAFIAALPLDHPGLIAEALFSDRFFLAVPAGDPAFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEEEECCCCCCCC
SPPVPPESPALERLMLLEEGHCLREQALAVCGNVRPVAMASYGATSLTTLLQMVAHGLGV
CCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHCCCE
TLIPEMATGPAGTIPDLKIVPFQEPMPQRMICLAWRRNNARHGECVELAKIIRSLGAAVL
EECCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
AA
CC
>Mature Secondary Structure
MIGLTVRQMHYFDALAQTLHFGRAAKLAGVSQPALSSQIAEMEQRLNCRLFERGGKSVRM
CCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHCCHHHHCCCCEEEE
TDEAIALLPRIERILADIRDVETTARRGRTAMEGRFRLGIIPTVAPYLLPRALPELKKHF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHH
PALLLELREAVTTSLVDDIASRKLDAFIAALPLDHPGLIAEALFSDRFFLAVPAGDPAFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEEEECCCCCCCC
SPPVPPESPALERLMLLEEGHCLREQALAVCGNVRPVAMASYGATSLTTLLQMVAHGLGV
CCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHCCCE
TLIPEMATGPAGTIPDLKIVPFQEPMPQRMICLAWRRNNARHGECVELAKIIRSLGAAVL
EECCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
AA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]