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The map label for this gene is tag [H]

Identifier: 13475764

GI number: 13475764

Start: 5693595

End: 5694233

Strand: Direct

Name: tag [H]

Synonym: mlr6925

Alternate gene names: 13475764

Gene position: 5693595-5694233 (Clockwise)

Preceding gene: 13475762

Following gene: 13475767

Centisome position: 80.92

GC content: 60.88

Gene sequence:

>639_bases
ATGAGCAATGAAAACACCGGCCTGCTTGCCGGTCCCGATGGTGTCGCGCGCTGCTTCTGGCACGGCAACCTGCCCGACTA
TCTGCACTACCATGATCATGAATGGGGCCGGCCGGTGGCAGACGACCGCAGGCTTTTCGAAAAGATCTGCCTTGAAGGTT
TTCAGTCGGGCCTGTCGTGGCTGACCATCCTGCGCAAACGCGAGAATTTTCGCGAGGCCTTCGCCGGCTTCGATTTCGAC
AAAATCGCCGCCTTCACCGACAAGGATGTCGAGCGCCTGCTCGGCAATGCCGGCATCATCCGCCATCGCGGCAAGATCGT
TTCGACCATCAACAACGCCAAACGCGCCCGCGAAATGGTCGACGAGTTCGGTTCGCTCGCCGCCTGGTTCTGGAAGTTCG
AACCCGGCAAGGCGGAGCGGCCCGAAATCGTCGACCTCGCCCATCTGCGCGCCAACCCGACGACGGCGGTCTCGGTGCGG
ATATCGAAGGAGTTGAAGAAGCGCGGCTGGAGTTTTGTCGGCCCGACCACGGTCTATGCCTTCATGCAGGCCATGGGCCT
GGTCAACGACCATCTCGAAGGCTGTGTCTGCCGCAAGCAGGTCGAGAAGGAACGCAAGGCTTTCAAACGGCCGACGTAG

Upstream 100 bases:

>100_bases
TGTCAGTAAACCTTTTGGTGTGGTTACCGCCGGGTTCAGGAATCTGGTAAAGCCACGGTAAAAGCAGCGCTAGAGCGCAT
TAACGGATGGATTTTTCGCA

Downstream 100 bases:

>100_bases
CTTCCTTCTCCCCGTTCACGGGAGAAGGTGCCGGCAGGCGGACGAGGGCGGCGCGAACTTGCGCAGGCTGGGCGTTACCC
CTCACCCTGCTCCGCCCGGC

Product: DNA-3-methyladenine glycosylase I

Products: NA

Alternate protein names: 3-methyladenine-DNA glycosylase I, constitutive; TAG I; DNA-3-methyladenine glycosidase I; DNA-3-methyladenine glycosylase I [H]

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MSNENTGLLAGPDGVARCFWHGNLPDYLHYHDHEWGRPVADDRRLFEKICLEGFQSGLSWLTILRKRENFREAFAGFDFD
KIAAFTDKDVERLLGNAGIIRHRGKIVSTINNAKRAREMVDEFGSLAAWFWKFEPGKAERPEIVDLAHLRANPTTAVSVR
ISKELKKRGWSFVGPTTVYAFMQAMGLVNDHLEGCVCRKQVEKERKAFKRPT

Sequences:

>Translated_212_residues
MSNENTGLLAGPDGVARCFWHGNLPDYLHYHDHEWGRPVADDRRLFEKICLEGFQSGLSWLTILRKRENFREAFAGFDFD
KIAAFTDKDVERLLGNAGIIRHRGKIVSTINNAKRAREMVDEFGSLAAWFWKFEPGKAERPEIVDLAHLRANPTTAVSVR
ISKELKKRGWSFVGPTTVYAFMQAMGLVNDHLEGCVCRKQVEKERKAFKRPT
>Mature_211_residues
SNENTGLLAGPDGVARCFWHGNLPDYLHYHDHEWGRPVADDRRLFEKICLEGFQSGLSWLTILRKRENFREAFAGFDFDK
IAAFTDKDVERLLGNAGIIRHRGKIVSTINNAKRAREMVDEFGSLAAWFWKFEPGKAERPEIVDLAHLRANPTTAVSVRI
SKELKKRGWSFVGPTTVYAFMQAMGLVNDHLEGCVCRKQVEKERKAFKRPT

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG2818

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789971, Length=182, Percent_Identity=50, Blast_Score=184, Evalue=4e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005019
- InterPro:   IPR011257
- InterPro:   IPR004597 [H]

Pfam domain/function: PF03352 Adenine_glyco [H]

EC number: =3.2.2.20 [H]

Molecular weight: Translated: 24266; Mature: 24135

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNENTGLLAGPDGVARCFWHGNLPDYLHYHDHEWGRPVADDRRLFEKICLEGFQSGLSW
CCCCCCCEEECCHHHHHEEECCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LTILRKRENFREAFAGFDFDKIAAFTDKDVERLLGNAGIIRHRGKIVSTINNAKRAREMV
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHH
DEFGSLAAWFWKFEPGKAERPEIVDLAHLRANPTTAVSVRISKELKKRGWSFVGPTTVYA
HHHHHHHHHHHEECCCCCCCCCHHHHHHHCCCCCEEEEEHHHHHHHHCCCCCCCHHHHHH
FMQAMGLVNDHLEGCVCRKQVEKERKAFKRPT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SNENTGLLAGPDGVARCFWHGNLPDYLHYHDHEWGRPVADDRRLFEKICLEGFQSGLSW
CCCCCCEEECCHHHHHEEECCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LTILRKRENFREAFAGFDFDKIAAFTDKDVERLLGNAGIIRHRGKIVSTINNAKRAREMV
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHH
DEFGSLAAWFWKFEPGKAERPEIVDLAHLRANPTTAVSVRISKELKKRGWSFVGPTTVYA
HHHHHHHHHHHEECCCCCCCCCHHHHHHHCCCCCEEEEEHHHHHHHHCCCCCCCHHHHHH
FMQAMGLVNDHLEGCVCRKQVEKERKAFKRPT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3536912; 3520491; 8041620; 9278503 [H]