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The map label for this gene is arcD [H]

Identifier: 13475619

GI number: 13475619

Start: 5528790

End: 5530220

Strand: Direct

Name: arcD [H]

Synonym: mlr6736

Alternate gene names: 13475619

Gene position: 5528790-5530220 (Clockwise)

Preceding gene: 13475618

Following gene: 13475622

Centisome position: 78.58

GC content: 58.91

Gene sequence:

>1431_bases
ATGGCATCCCAGACCTCGCAGAAGCTTTCTCTCGCCGCACTGACGGCGATGGTTGTCGGGTCGATGATCGGCGCCGGCAT
ATTTGCGCTGCCGCGCACCTTTGGCGCCGCCACCGGACCGATTGGAGCCGTCATCGCCTGGTGTATCGCCGGGACCGGGA
TGTATACATTGGCCCTGGTCTTTCAGGCGCTTGCGGCGCGCAAGCCCGAGCTCGATGCCGGCATCTTTTCCTATGCAAAA
GCCGGCTTCGGTGACTACGCCGGTTTTCTCTCCGCGTTTGGCTATTGGCTGGTTGCCTGCATTGCCGACGTCTCATACTG
GGTTCTGATCAAGTCGACGCTCGGCGCGTTCTTCCCGGTTTTCGGCAACGGCGACACGGTCCCGGCAGTGGTGGTCTCGT
CGATCGCACTCTGGCTGTTCCACTTCACGATCCTGCGCGGGATCAGGGAAGCTGCCTTCATCAACACCGTTGTCACGGTC
GCAAAAGTTATTCCCATTCTTGTCTTCATTTTGATTCTGGCTGGAACGTCCAACGCGAACATCTTCGTCACCAACCTGTG
GGGCGGAGAACTGGCAGCGCGAAGCGGTCTCTTCGAGCAGATACGAGCGACCATGCTGGTCACAATCTTTGTGTTCATCG
GGATTGAGGGAGCAAGCGTCTATTCTCGCTATGCGAAGGACCGCGCCGACGTCGGACGCGCGACGATCCTTGGCTTCATC
GGCGTGCTGTTCCTGCTGGTCCTGGTGACGCTCCTGCCTTATGCCGTGCTTCCGCAGGCGGAAATCGCCGGCTTGCGCCA
GCCCTCGATGGCTGCCGTGCTGGAGGCCGTCGTTGGTCACTGGGGCGCTGTTTTCGTCAGCGTGGGGCTGATCGTATCGT
TGCTCGGCGCTTATCTCGCCTGGTCGTTGATCTGTGTCGAGGTGCTGTTCGCGGCCGCAAAGAGCGGCGACATGCCAAGG
ATTTTTGCGCGTGAAAATCGCAACAACGTCCCGGCCGCCGCGCTGTGGCTGACCAATGTGATCATTCAAGCTTTCCTCAT
AAGCACGCTTTTCTCGCAAGATGCGTTCGCGCTCATGGTGAAGTTGAGCAGTGCCATGGTGTTGATACCTTACCTGCTCG
TGGCCGGGTACGGCTTCCTTCTCGCCTTGCGCCGAGAAACCTATGACGCCGAACCGGCACAACGATCCCGCGACCTGATC
GTGGCCGGCATTGCCACATTGTATGTTGCGTTCATGATCTACGCAGGCGGCCTGAAATTTCTATTGCTGTCATCCATTCT
CTACGCACCCGGTACGCTGCTCTATGTTCAGGTCAGACGGGAGCAGAACATGCCGGTGTTGGTCGGCGTGGAATGGATAG
TGTTGGCGGCCGCGGCAATTGGTTGCCTCGTTGGCATTTACGGAATTGCCAGCGGCGACATCGTTCTCTAG

Upstream 100 bases:

>100_bases
GCCGATGCAGCATCGGGTGGTCGACCAGTGCAGCGACCTGCCGGATCGGCTTGGCGGACGGATTTCGCTTGTGCAGTGAC
CACCGACTCGAGACGCGGCC

Downstream 100 bases:

>100_bases
CCGAGCGAGCGGGGGTATTCCACTCGCCGAAGTCGCTCATATAGGGAGACTTCGTCCAGCTTGCCCTCGGAAAGAAGTTC
GACAGCGCTCGTGCGCAGTT

Product: arginine/ornithine antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 476; Mature: 475

Protein sequence:

>476_residues
MASQTSQKLSLAALTAMVVGSMIGAGIFALPRTFGAATGPIGAVIAWCIAGTGMYTLALVFQALAARKPELDAGIFSYAK
AGFGDYAGFLSAFGYWLVACIADVSYWVLIKSTLGAFFPVFGNGDTVPAVVVSSIALWLFHFTILRGIREAAFINTVVTV
AKVIPILVFILILAGTSNANIFVTNLWGGELAARSGLFEQIRATMLVTIFVFIGIEGASVYSRYAKDRADVGRATILGFI
GVLFLLVLVTLLPYAVLPQAEIAGLRQPSMAAVLEAVVGHWGAVFVSVGLIVSLLGAYLAWSLICVEVLFAAAKSGDMPR
IFARENRNNVPAAALWLTNVIIQAFLISTLFSQDAFALMVKLSSAMVLIPYLLVAGYGFLLALRRETYDAEPAQRSRDLI
VAGIATLYVAFMIYAGGLKFLLLSSILYAPGTLLYVQVRREQNMPVLVGVEWIVLAAAAIGCLVGIYGIASGDIVL

Sequences:

>Translated_476_residues
MASQTSQKLSLAALTAMVVGSMIGAGIFALPRTFGAATGPIGAVIAWCIAGTGMYTLALVFQALAARKPELDAGIFSYAK
AGFGDYAGFLSAFGYWLVACIADVSYWVLIKSTLGAFFPVFGNGDTVPAVVVSSIALWLFHFTILRGIREAAFINTVVTV
AKVIPILVFILILAGTSNANIFVTNLWGGELAARSGLFEQIRATMLVTIFVFIGIEGASVYSRYAKDRADVGRATILGFI
GVLFLLVLVTLLPYAVLPQAEIAGLRQPSMAAVLEAVVGHWGAVFVSVGLIVSLLGAYLAWSLICVEVLFAAAKSGDMPR
IFARENRNNVPAAALWLTNVIIQAFLISTLFSQDAFALMVKLSSAMVLIPYLLVAGYGFLLALRRETYDAEPAQRSRDLI
VAGIATLYVAFMIYAGGLKFLLLSSILYAPGTLLYVQVRREQNMPVLVGVEWIVLAAAAIGCLVGIYGIASGDIVL
>Mature_475_residues
ASQTSQKLSLAALTAMVVGSMIGAGIFALPRTFGAATGPIGAVIAWCIAGTGMYTLALVFQALAARKPELDAGIFSYAKA
GFGDYAGFLSAFGYWLVACIADVSYWVLIKSTLGAFFPVFGNGDTVPAVVVSSIALWLFHFTILRGIREAAFINTVVTVA
KVIPILVFILILAGTSNANIFVTNLWGGELAARSGLFEQIRATMLVTIFVFIGIEGASVYSRYAKDRADVGRATILGFIG
VLFLLVLVTLLPYAVLPQAEIAGLRQPSMAAVLEAVVGHWGAVFVSVGLIVSLLGAYLAWSLICVEVLFAAAKSGDMPRI
FARENRNNVPAAALWLTNVIIQAFLISTLFSQDAFALMVKLSSAMVLIPYLLVAGYGFLLALRRETYDAEPAQRSRDLIV
AGIATLYVAFMIYAGGLKFLLLSSILYAPGTLLYVQVRREQNMPVLVGVEWIVLAAAAIGCLVGIYGIASGDIVL

Specific function: Catalyzes an electroneutral exchange between arginine and ornithine to allow high-efficiency energy conversion in the arginine deiminase pathway [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI1787890, Length=455, Percent_Identity=40.2197802197802, Blast_Score=325, Evalue=5e-90,
Organism=Escherichia coli, GI2367353, Length=454, Percent_Identity=27.9735682819383, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI1786908, Length=442, Percent_Identity=23.5294117647059, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790575, Length=381, Percent_Identity=25.1968503937008, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1788480, Length=386, Percent_Identity=25.6476683937824, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004754
- InterPro:   IPR022461 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50627; Mature: 50496

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASQTSQKLSLAALTAMVVGSMIGAGIFALPRTFGAATGPIGAVIAWCIAGTGMYTLALV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHH
FQALAARKPELDAGIFSYAKAGFGDYAGFLSAFGYWLVACIADVSYWVLIKSTLGAFFPV
HHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FGNGDTVPAVVVSSIALWLFHFTILRGIREAAFINTVVTVAKVIPILVFILILAGTSNAN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
IFVTNLWGGELAARSGLFEQIRATMLVTIFVFIGIEGASVYSRYAKDRADVGRATILGFI
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
GVLFLLVLVTLLPYAVLPQAEIAGLRQPSMAAVLEAVVGHWGAVFVSVGLIVSLLGAYLA
HHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WSLICVEVLFAAAKSGDMPRIFARENRNNVPAAALWLTNVIIQAFLISTLFSQDAFALMV
HHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
KLSSAMVLIPYLLVAGYGFLLALRRETYDAEPAQRSRDLIVAGIATLYVAFMIYAGGLKF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHCCHHH
LLLSSILYAPGTLLYVQVRREQNMPVLVGVEWIVLAAAAIGCLVGIYGIASGDIVL
HHHHHHHHCCCCEEEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
ASQTSQKLSLAALTAMVVGSMIGAGIFALPRTFGAATGPIGAVIAWCIAGTGMYTLALV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHH
FQALAARKPELDAGIFSYAKAGFGDYAGFLSAFGYWLVACIADVSYWVLIKSTLGAFFPV
HHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FGNGDTVPAVVVSSIALWLFHFTILRGIREAAFINTVVTVAKVIPILVFILILAGTSNAN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
IFVTNLWGGELAARSGLFEQIRATMLVTIFVFIGIEGASVYSRYAKDRADVGRATILGFI
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
GVLFLLVLVTLLPYAVLPQAEIAGLRQPSMAAVLEAVVGHWGAVFVSVGLIVSLLGAYLA
HHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WSLICVEVLFAAAKSGDMPRIFARENRNNVPAAALWLTNVIIQAFLISTLFSQDAFALMV
HHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
KLSSAMVLIPYLLVAGYGFLLALRRETYDAEPAQRSRDLIVAGIATLYVAFMIYAGGLKF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHCCHHH
LLLSSILYAPGTLLYVQVRREQNMPVLVGVEWIVLAAAAIGCLVGIYGIASGDIVL
HHHHHHHHCCCCEEEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2158926; 10984043; 1311296 [H]