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The map label for this gene is arcD [H]

Identifier: 13475617

GI number: 13475617

Start: 5527075

End: 5528508

Strand: Reverse

Name: arcD [H]

Synonym: mll6735

Alternate gene names: 13475617

Gene position: 5528508-5527075 (Counterclockwise)

Preceding gene: 13475620

Following gene: 13475616

Centisome position: 78.57

GC content: 63.18

Gene sequence:

>1434_bases
GTGACAGGTAAGTCCGAGCAGAAGCTGTCCTTGTTCGCCTTGATCGGAATGGTCGTCGGATCGATGATCGGGGCCGGCAT
CTTCAATCTGCCCGGCAGGTTCGCCACCGCGACAGGCCCGTTCGGCGCCATCATCGCCTGGTGTATCGCCGGGACCGGCA
TGTACATGCTGGCCCGAGTGTTCCAGGCGCTGGCCGAGAAGAGACCCGATATCGATTCCGGCGTCTTCGCCTACGCGAAG
GCGGGATTCGGCGACTATATGGGCTTCCTCTCGGCGTTCGGCTATTGGCTCGGAAGCTGCCTCGGAAACGTCTTCTACTG
GGTGCTGATCGGATCGACGCTCGGGCGCTTCTTCCCAGGGATTTTCGGGGATGGCAGCACCGCGATCGCGATCATCGTCT
CGCTGGTCGGCATCTGGGCCTTCCATTTCATGATCCTGCGCGGCGTCGAGCAGGCCACCTTCATCAACAGCGTGGTGACG
GTCGCCAAGATCGTACCGATCATCGTGGCGATCCTCGCCATGGCGATCGCGTTCAACTACACGCAATTCTCCGAGAACTT
TCTCGGCGGCGTGGGCATGCCGGAAAAGACCCTGGTGGCGCAGGTGCGCGACACCATGCTGATCACCGTTTTCGTCTTCC
TCGGTATCGAGGGGGCGAGCGTGTATTCGCGCTTCGCCCAGAAGCGTTCGGACGTCGGCACCGCCACCATTCTGGGTTTT
GTCGGCGTCACCGGCCTGATGGTGGCCATCACCCTGCTGCCCTACGCCACGGCTCCCCGTGCCGCCATCGCCGGGGTCCA
GCAGCCCTCGCTTGCCGGCGCGCTCGAACTGGTCGTGGGACATTGGGGCGCGGTGTTCATTTCCGTCGGCGTGCTGGTGT
CAGTGCTCGGCGCGTATCTCGCCTGGTCGCTGATCTGCGCCGAGGTGCTGTTCGCCGCCGCAAAGTCGCAGGACATGCCG
AAGCTTTTCGCGGCGCAGAACGGCAACCGGGTTCCCGCCAACGCGCTTTGGCTGACCAACATCGTCGTCTCGCTATTCAT
CATCTCAACCTACTGGTCACGCGACGCCTTCAACTTCATGCTCGACATGACAAGCGTGACGGCGCTGCTGCCCTACCTGC
TGGTCGCGGGCTATGGCGTGCTGATCGCCCGTCGCGGCGAGGGGTACCAGACCACGCCCGGCGAACGCGGGCGCGACCAG
CTATTCGCCTGGATCGCCGTCGTCTACACCCTCATCATGTTTGTGGCCGCCGGCTTGAAATACGTGCTTCTGGTGGCGGT
GCTCTTCGTGCCGGGAACCATCCTCTACCTGTGGGCGCGGCGCGAACAGAAGGCGCGGTTCTTCACATCGGTCGAACTCA
TCATCTTCGCCGTCACCCTGGTCGCCGGCCTTGCTGGTTTCGTCGGCCTGCTGACCGGCGCCATTACACCTTGA

Upstream 100 bases:

>100_bases
CGTGAGATTCTCAGCTAATTTCACGCTCATTTCAAAAGCATAGATTTACTTCGCCCATCGAAGGCGGGCTCGCTTGGTCG
CCCATCACCGGGAGAGAGAC

Downstream 100 bases:

>100_bases
CGAGAAAGGCCCGAGCCATGGCGATGGAAACGAAATTCGGCGTGCATTCCGAAGTCGGCCAGCTTCGCAAGGTCATGGTC
TGCGCGCCCGGCCGCGCCCA

Product: arginine/ornithine antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 477; Mature: 476

Protein sequence:

>477_residues
MTGKSEQKLSLFALIGMVVGSMIGAGIFNLPGRFATATGPFGAIIAWCIAGTGMYMLARVFQALAEKRPDIDSGVFAYAK
AGFGDYMGFLSAFGYWLGSCLGNVFYWVLIGSTLGRFFPGIFGDGSTAIAIIVSLVGIWAFHFMILRGVEQATFINSVVT
VAKIVPIIVAILAMAIAFNYTQFSENFLGGVGMPEKTLVAQVRDTMLITVFVFLGIEGASVYSRFAQKRSDVGTATILGF
VGVTGLMVAITLLPYATAPRAAIAGVQQPSLAGALELVVGHWGAVFISVGVLVSVLGAYLAWSLICAEVLFAAAKSQDMP
KLFAAQNGNRVPANALWLTNIVVSLFIISTYWSRDAFNFMLDMTSVTALLPYLLVAGYGVLIARRGEGYQTTPGERGRDQ
LFAWIAVVYTLIMFVAAGLKYVLLVAVLFVPGTILYLWARREQKARFFTSVELIIFAVTLVAGLAGFVGLLTGAITP

Sequences:

>Translated_477_residues
MTGKSEQKLSLFALIGMVVGSMIGAGIFNLPGRFATATGPFGAIIAWCIAGTGMYMLARVFQALAEKRPDIDSGVFAYAK
AGFGDYMGFLSAFGYWLGSCLGNVFYWVLIGSTLGRFFPGIFGDGSTAIAIIVSLVGIWAFHFMILRGVEQATFINSVVT
VAKIVPIIVAILAMAIAFNYTQFSENFLGGVGMPEKTLVAQVRDTMLITVFVFLGIEGASVYSRFAQKRSDVGTATILGF
VGVTGLMVAITLLPYATAPRAAIAGVQQPSLAGALELVVGHWGAVFISVGVLVSVLGAYLAWSLICAEVLFAAAKSQDMP
KLFAAQNGNRVPANALWLTNIVVSLFIISTYWSRDAFNFMLDMTSVTALLPYLLVAGYGVLIARRGEGYQTTPGERGRDQ
LFAWIAVVYTLIMFVAAGLKYVLLVAVLFVPGTILYLWARREQKARFFTSVELIIFAVTLVAGLAGFVGLLTGAITP
>Mature_476_residues
TGKSEQKLSLFALIGMVVGSMIGAGIFNLPGRFATATGPFGAIIAWCIAGTGMYMLARVFQALAEKRPDIDSGVFAYAKA
GFGDYMGFLSAFGYWLGSCLGNVFYWVLIGSTLGRFFPGIFGDGSTAIAIIVSLVGIWAFHFMILRGVEQATFINSVVTV
AKIVPIIVAILAMAIAFNYTQFSENFLGGVGMPEKTLVAQVRDTMLITVFVFLGIEGASVYSRFAQKRSDVGTATILGFV
GVTGLMVAITLLPYATAPRAAIAGVQQPSLAGALELVVGHWGAVFISVGVLVSVLGAYLAWSLICAEVLFAAAKSQDMPK
LFAAQNGNRVPANALWLTNIVVSLFIISTYWSRDAFNFMLDMTSVTALLPYLLVAGYGVLIARRGEGYQTTPGERGRDQL
FAWIAVVYTLIMFVAAGLKYVLLVAVLFVPGTILYLWARREQKARFFTSVELIIFAVTLVAGLAGFVGLLTGAITP

Specific function: Catalyzes an electroneutral exchange between arginine and ornithine to allow high-efficiency energy conversion in the arginine deiminase pathway [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI1787890, Length=464, Percent_Identity=37.5, Blast_Score=296, Evalue=2e-81,
Organism=Escherichia coli, GI2367353, Length=426, Percent_Identity=24.8826291079812, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1790575, Length=378, Percent_Identity=24.3386243386243, Blast_Score=79, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004754
- InterPro:   IPR022461 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50992; Mature: 50861

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TGKSEQKLSLFALIGMVVGSMIGAGIFNLPGRFATATGPFGAIIAWCIAGTGMYMLARV
CCCCHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHH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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2158926; 10984043; 1311296 [H]