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The map label for this gene is 13475576

Identifier: 13475576

GI number: 13475576

Start: 5478143

End: 5479477

Strand: Direct

Name: 13475576

Synonym: mlr6682

Alternate gene names: NA

Gene position: 5478143-5479477 (Clockwise)

Preceding gene: 13475575

Following gene: 13475577

Centisome position: 77.86

GC content: 61.87

Gene sequence:

>1335_bases
ATGTTGGCGGCAATCCTGGATGGGTTGGCACAGGAGAGTCCCATGTCTGCGCGCTTGCTATCACCAACACGGCGGGAAGT
CCTGATCACCGCGGCTGCCTTAGGAGCCATCAGCATGCTTTCGTCAAAATCCAAAGCGGCTGCGGAAGCCGCGTCAATCC
ATCCTTTCCAGTTCAGGGCTTCCGATGAGGATCTCGCCGATCTGAAGCGGCGTGTCGCGGCGACGCGCTGGCCGGACAGG
GAGACGGTGCCGGACCAGTCGCAGGGCGTGCAGCTCGACATCGCGCGCCAGATCCAGGTGCACTGGGCCAATCATGATTG
GCGCAAGGTCGAGGCCAGGATGATGGCGTATCCGCACTTCATCACCGAGATCGATGGGCTCGACATCCACTTCATTCACG
TGAAGTCGAAGCACAAAAACGCGCTGCCGATGATCGTGACCCATGGCTGGCCGGGCTCGGTTATCGAGCAGTTGAAGATC
ATCGAACCGCTCACCGACCCGACCGCGCATGGCGGCACCGAAGCGGATGCATTCGATCTCGTGGTTCCGTCATTGCCCGG
CTACGGATTCTCCGGCAAGCCGACGACACCAGGATGGGAGCCTGTCCGTATCGCCAAGGCGTGGGCAACCCTTATGGAAC
GCCTCGGCTACAACAAATATGTGGCCCAGGGCGGCGACTGGGGCAATGCGGTTACCGAGAATATGGCGCTACAGGAGCCG
CCGGGACTGCTTGGCATCCACACCAACATGGCGGCGACGCTTCCACCTGAAATCTCCAAGGCGCTTGGGACCGGCACGCC
GCCGCCAGGGCTCGGTCCCGACGAGAAGCGCGCTTTCGACCAGCTCATCTATTTCAATCAGCATGGGCTTGGCTATGCCA
TCGAGATGAACCAACGTCCTCAGACGCTCTACGGCATCGTCGACTCGCCCGTCGGCCTCGCCGCCTGGATGCTGGACCAC
GACGCCGACAGTCACGCCCTGATCGCCCGCTCCTTTAGCGGGAAGCCCGAGGGCATCACGCCGGACGACTTTCTCGACAA
CGTCACCTTCTACTGGCTGACGAACACGGCGGTCTCGTCGGGACGACTCTACTGGGACAATGCGCGGGTCGCGAAAGGCG
GTTTCTTCGACGCGCGTGGCATCAGGATACCGGTCGCGGTGAGCGCTTTCGCCAACGAGATCTACCAGGCGCCGGAGAGC
TGGGCGAAGACAGCCTATCCAAAGCTTCTCCATTACGGCCGCTTCCCCATTGGCTGCCATTTCGCCGCCTGGGAGCAGCC
CGAAATCTTTGTCGAGGAGATGCGTGCGTCGTTCAAGACGCTGCGCGCGTCCTGA

Upstream 100 bases:

>100_bases
ATGCGGCTGCTTGCAAAAATTCGCATCTCTTAGCGCCTCTTAACTCGCTTCGACGACAGCAGCAGGGCACTTTGGTCGTG
TCACAACGAAGCAGCCGTCG

Downstream 100 bases:

>100_bases
GGACTGCGACGGAAAAATAGTCTCCATTCTGAGCGCCGCCTCGGCGGTAGTCAGATGGTCAGCGTAACAGGACAAGACGA
TCCCGCACCCCGGCGTGCGG

Product: epoxide hydrolase

Products: NA

Alternate protein names: Epoxide hydratase [H]

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MLAAILDGLAQESPMSARLLSPTRREVLITAAALGAISMLSSKSKAAAEAASIHPFQFRASDEDLADLKRRVAATRWPDR
ETVPDQSQGVQLDIARQIQVHWANHDWRKVEARMMAYPHFITEIDGLDIHFIHVKSKHKNALPMIVTHGWPGSVIEQLKI
IEPLTDPTAHGGTEADAFDLVVPSLPGYGFSGKPTTPGWEPVRIAKAWATLMERLGYNKYVAQGGDWGNAVTENMALQEP
PGLLGIHTNMAATLPPEISKALGTGTPPPGLGPDEKRAFDQLIYFNQHGLGYAIEMNQRPQTLYGIVDSPVGLAAWMLDH
DADSHALIARSFSGKPEGITPDDFLDNVTFYWLTNTAVSSGRLYWDNARVAKGGFFDARGIRIPVAVSAFANEIYQAPES
WAKTAYPKLLHYGRFPIGCHFAAWEQPEIFVEEMRASFKTLRAS

Sequences:

>Translated_444_residues
MLAAILDGLAQESPMSARLLSPTRREVLITAAALGAISMLSSKSKAAAEAASIHPFQFRASDEDLADLKRRVAATRWPDR
ETVPDQSQGVQLDIARQIQVHWANHDWRKVEARMMAYPHFITEIDGLDIHFIHVKSKHKNALPMIVTHGWPGSVIEQLKI
IEPLTDPTAHGGTEADAFDLVVPSLPGYGFSGKPTTPGWEPVRIAKAWATLMERLGYNKYVAQGGDWGNAVTENMALQEP
PGLLGIHTNMAATLPPEISKALGTGTPPPGLGPDEKRAFDQLIYFNQHGLGYAIEMNQRPQTLYGIVDSPVGLAAWMLDH
DADSHALIARSFSGKPEGITPDDFLDNVTFYWLTNTAVSSGRLYWDNARVAKGGFFDARGIRIPVAVSAFANEIYQAPES
WAKTAYPKLLHYGRFPIGCHFAAWEQPEIFVEEMRASFKTLRAS
>Mature_444_residues
MLAAILDGLAQESPMSARLLSPTRREVLITAAALGAISMLSSKSKAAAEAASIHPFQFRASDEDLADLKRRVAATRWPDR
ETVPDQSQGVQLDIARQIQVHWANHDWRKVEARMMAYPHFITEIDGLDIHFIHVKSKHKNALPMIVTHGWPGSVIEQLKI
IEPLTDPTAHGGTEADAFDLVVPSLPGYGFSGKPTTPGWEPVRIAKAWATLMERLGYNKYVAQGGDWGNAVTENMALQEP
PGLLGIHTNMAATLPPEISKALGTGTPPPGLGPDEKRAFDQLIYFNQHGLGYAIEMNQRPQTLYGIVDSPVGLAAWMLDH
DADSHALIARSFSGKPEGITPDDFLDNVTFYWLTNTAVSSGRLYWDNARVAKGGFFDARGIRIPVAVSAFANEIYQAPES
WAKTAYPKLLHYGRFPIGCHFAAWEQPEIFVEEMRASFKTLRAS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

Organism=Homo sapiens, GI4503583, Length=455, Percent_Identity=33.8461538461538, Blast_Score=236, Evalue=3e-62,
Organism=Homo sapiens, GI209862837, Length=455, Percent_Identity=33.8461538461538, Blast_Score=236, Evalue=3e-62,
Organism=Caenorhabditis elegans, GI17564944, Length=418, Percent_Identity=32.7751196172249, Blast_Score=199, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI193207462, Length=396, Percent_Identity=26.010101010101, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI20130139, Length=409, Percent_Identity=31.7848410757946, Blast_Score=181, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24655327, Length=409, Percent_Identity=29.3398533007335, Blast_Score=170, Evalue=2e-42,
Organism=Drosophila melanogaster, GI19922580, Length=414, Percent_Identity=27.536231884058, Blast_Score=155, Evalue=5e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =3.3.2.10 [H]

Molecular weight: Translated: 48873; Mature: 48873

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAAILDGLAQESPMSARLLSPTRREVLITAAALGAISMLSSKSKAAAEAASIHPFQFRA
CHHHHHHHHHCCCCCCHHHCCCCHHHHEEHHHHHHHHHHHHCCHHHHHHHHCCCCEEECC
SDEDLADLKRRVAATRWPDRETVPDQSQGVQLDIARQIQVHWANHDWRKVEARMMAYPHF
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEEEEEECCCCHHHHHHHHHHCCHH
ITEIDGLDIHFIHVKSKHKNALPMIVTHGWPGSVIEQLKIIEPLTDPTAHGGTEADAFDL
HHHCCCCEEEEEEEECCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEE
VVPSLPGYGFSGKPTTPGWEPVRIAKAWATLMERLGYNKYVAQGGDWGNAVTENMALQEP
EECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHCCCCCCCC
PGLLGIHTNMAATLPPEISKALGTGTPPPGLGPDEKRAFDQLIYFNQHGLGYAIEMNQRP
CCEEEEECCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHEECCCCCEEEEEECCCC
QTLYGIVDSPVGLAAWMLDHDADSHALIARSFSGKPEGITPDDFLDNVTFYWLTNTAVSS
CEEEEECCCCCHHEEEEECCCCCCCEEEEECCCCCCCCCCHHHHHCCCEEEEEECCCCCC
GRLYWDNARVAKGGFFDARGIRIPVAVSAFANEIYQAPESWAKTAYPKLLHYGRFPIGCH
CEEEECCCEEECCCCCCCCCCEEEEHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCEEE
FAAWEQPEIFVEEMRASFKTLRAS
ECCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLAAILDGLAQESPMSARLLSPTRREVLITAAALGAISMLSSKSKAAAEAASIHPFQFRA
CHHHHHHHHHCCCCCCHHHCCCCHHHHEEHHHHHHHHHHHHCCHHHHHHHHCCCCEEECC
SDEDLADLKRRVAATRWPDRETVPDQSQGVQLDIARQIQVHWANHDWRKVEARMMAYPHF
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEEEEEECCCCHHHHHHHHHHCCHH
ITEIDGLDIHFIHVKSKHKNALPMIVTHGWPGSVIEQLKIIEPLTDPTAHGGTEADAFDL
HHHCCCCEEEEEEEECCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEE
VVPSLPGYGFSGKPTTPGWEPVRIAKAWATLMERLGYNKYVAQGGDWGNAVTENMALQEP
EECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHCCCCCCCC
PGLLGIHTNMAATLPPEISKALGTGTPPPGLGPDEKRAFDQLIYFNQHGLGYAIEMNQRP
CCEEEEECCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHEECCCCCEEEEEECCCC
QTLYGIVDSPVGLAAWMLDHDADSHALIARSFSGKPEGITPDDFLDNVTFYWLTNTAVSS
CEEEEECCCCCHHEEEEECCCCCCCEEEEECCCCCCCCCCHHHHHCCCEEEEEECCCCCC
GRLYWDNARVAKGGFFDARGIRIPVAVSAFANEIYQAPESWAKTAYPKLLHYGRFPIGCH
CEEEECCCEEECCCCCCCCCCEEEEHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCEEE
FAAWEQPEIFVEEMRASFKTLRAS
ECCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8226695 [H]