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The map label for this gene is bioD [H]

Identifier: 13475242

GI number: 13475242

Start: 5086758

End: 5087393

Strand: Reverse

Name: bioD [H]

Synonym: mll6270

Alternate gene names: 13475242

Gene position: 5087393-5086758 (Counterclockwise)

Preceding gene: 13475243

Following gene: 13475241

Centisome position: 72.3

GC content: 61.64

Gene sequence:

>636_bases
ATGACCAAGCGTATCGTCATCACCGGGACAGACACCGGAATTGGCAAGACCGTGTTTTCGGCAGGGCTCGCCGGCCTGCT
CGACGGTTTCTACTGGAAGCCGGTGCAATCGGATCTCGACGCCGAGACCGACAGCGAGGTCGTTGCACGGCTTGCCGGCC
TGCCGCCAGGCCGCGTGCTGCCGGAAGCCTACCGCTTGCAGAGCCCGCTTTCGCCGCACCGTCCGGCCGAAATCGACGGC
ATCTCGATCGAGACTGCCGATCTTTCATTTCCGGTCCTGCCGACACCGCTCGTCATCGAAGGCGCCGGCGGGCTCATGGC
GCCGCTCAACCGACAGACAACGTTCATCGATATTTTCCGGGAATGGCAACTACCCGTCATCCTTTGCGCACGCACCGCGC
TCAGCACCATCAATCACACTGTGCTATCGATCGAGGCGCTCAAGGCTCGCTCCATCCCAATCATGGGCGTTGCTTTCATC
GGCGACGAGGTGGCCGACAGCCAAAGGACGATCGCTGAGTTGGGCAATGTGCCACAACTCGGCAGGCTGCCGCACCTCGA
TCCACTGACGCCCAAAACGCTGAGGCAAGCGATGATTGCCAGCTTCGACCTAGACCTGATTGCCGGACGCCAATGA

Upstream 100 bases:

>100_bases
AGCTGGGCACGCCGGCCGGCGCCACCGGGTCGCGGCTGCATGTCGACGAACCCGACATTTCCGCCATGATCGACGCGCTC
TTCGAGGTGTTGGGCAAGGC

Downstream 100 bases:

>100_bases
TGTCGCAGTCTCGTCTGTGGCATCCGTTCACGCAAGCACGTACTCGAGCCGGCAATCCCCGAGATCGTCCGGAGGGAAGT
CGCCTACCCTCCACAAGGCC

Product: dithiobiotin synthetase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 211; Mature: 210

Protein sequence:

>211_residues
MTKRIVITGTDTGIGKTVFSAGLAGLLDGFYWKPVQSDLDAETDSEVVARLAGLPPGRVLPEAYRLQSPLSPHRPAEIDG
ISIETADLSFPVLPTPLVIEGAGGLMAPLNRQTTFIDIFREWQLPVILCARTALSTINHTVLSIEALKARSIPIMGVAFI
GDEVADSQRTIAELGNVPQLGRLPHLDPLTPKTLRQAMIASFDLDLIAGRQ

Sequences:

>Translated_211_residues
MTKRIVITGTDTGIGKTVFSAGLAGLLDGFYWKPVQSDLDAETDSEVVARLAGLPPGRVLPEAYRLQSPLSPHRPAEIDG
ISIETADLSFPVLPTPLVIEGAGGLMAPLNRQTTFIDIFREWQLPVILCARTALSTINHTVLSIEALKARSIPIMGVAFI
GDEVADSQRTIAELGNVPQLGRLPHLDPLTPKTLRQAMIASFDLDLIAGRQ
>Mature_210_residues
TKRIVITGTDTGIGKTVFSAGLAGLLDGFYWKPVQSDLDAETDSEVVARLAGLPPGRVLPEAYRLQSPLSPHRPAEIDGI
SIETADLSFPVLPTPLVIEGAGGLMAPLNRQTTFIDIFREWQLPVILCARTALSTINHTVLSIEALKARSIPIMGVAFIG
DEVADSQRTIAELGNVPQLGRLPHLDPLTPKTLRQAMIASFDLDLIAGRQ

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=210, Percent_Identity=30, Blast_Score=74, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6324385, Length=190, Percent_Identity=31.5789473684211, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472 [H]

Pfam domain/function: NA

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 22699; Mature: 22567

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKRIVITGTDTGIGKTVFSAGLAGLLDGFYWKPVQSDLDAETDSEVVARLAGLPPGRVL
CCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCC
PEAYRLQSPLSPHRPAEIDGISIETADLSFPVLPTPLVIEGAGGLMAPLNRQTTFIDIFR
CHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEECCCCCCCCCCCCHHHEEHHH
EWQLPVILCARTALSTINHTVLSIEALKARSIPIMGVAFIGDEVADSQRTIAELGNVPQL
HCCCHHHHHHHHHHHHHHHHHEEEEHHHHCCCCEEEEEECCCHHHHHHHHHHHHCCCCCC
GRLPHLDPLTPKTLRQAMIASFDLDLIAGRQ
CCCCCCCCCCHHHHHHHHHHHCCHHEECCCC
>Mature Secondary Structure 
TKRIVITGTDTGIGKTVFSAGLAGLLDGFYWKPVQSDLDAETDSEVVARLAGLPPGRVL
CCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCC
PEAYRLQSPLSPHRPAEIDGISIETADLSFPVLPTPLVIEGAGGLMAPLNRQTTFIDIFR
CHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEECCCCCCCCCCCCHHHEEHHH
EWQLPVILCARTALSTINHTVLSIEALKARSIPIMGVAFIGDEVADSQRTIAELGNVPQL
HCCCHHHHHHHHHHHHHHHHHEEEEHHHHCCCCEEEEEECCCHHHHHHHHHHHHCCCCCC
GRLPHLDPLTPKTLRQAMIASFDLDLIAGRQ
CCCCCCCCCCHHHHHHHHHHHCCHHEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA