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The map label for this gene is kdgR [H]

Identifier: 13475230

GI number: 13475230

Start: 5078672

End: 5079481

Strand: Direct

Name: kdgR [H]

Synonym: mlr8761

Alternate gene names: 13475230

Gene position: 5078672-5079481 (Clockwise)

Preceding gene: 13475220

Following gene: 13475231

Centisome position: 72.18

GC content: 54.57

Gene sequence:

>810_bases
GTGAGTTCTGTCAAACATTCCCCAAATGACCAGGACCGAGCTCCCGGTGAGGTTTCGACGGTACAGAGAGCATTGAACTT
GCTGAAACTGCTCGGCACAACTGAAAAGCCGATAGGTGTGAATGAGATCGCGCGCCGGCTAGGGAAGCATGTAAGTGCAG
TCTCAAGGACGCTGGCCACGCTGGAGCACAATGGCTTCGTCGAGCGTGACGAGGAGACTGGGCGGTTTGTGCTCGGAGTT
GAGCTTATCGCGCTTGCGAGCAGACTCCTTGCTGAACACGACGTGGTTCGTGTGGCGCGACCCTACCTCGAGGAACTTGC
CGAGAGCACGAGGGAAACGACCTCCCTCAGTCTTTGGAATAAGACACACGCTATCAACGTTGAGCATGTGCTTGGCCCCG
GGTCGATCAAGCACATCGCTGCACCGGGGCGCCGTAACCCGGCACACTGCACGGCTACTGGAAAAGCCATGTTGTCACAC
ATGCCAGACTCCACACTGAGAGAAGTATTAGCGCTCGGACTAGAACGTTACACAGATCGTACGACTACTGAGGTGAGCGC
TCTTGAAAGTGAGTTGGACCATATTCGCAAGCAAGGATACGCGTTGAATGTTGGGGAGTTCATTCCTGAGATTGCCGCCG
TCGCGGCCGTTATCCATGACCGGAGGGGACGAGTTGCCGCTGCAATTGCCGTTACAATGCCGGTTTTTCATTTTACTCAG
CAAATTGAACAACAGCTGGCGCCACTTGTCATAAATGCGGCGGCGGCTATCTCTAAGCGTTTAGGATATCACAGTGCCCA
GCCAATTTAG

Upstream 100 bases:

>100_bases
CTAAGGGCGAGCACCCGCGATGGAATGTCAAATTGCAAATAATGCAGCGGTGTTGCAAACTTCACGAAAATAGATGCGCA
ATTGGACTAAGGAGCCTTCC

Downstream 100 bases:

>100_bases
CTTGCAAATGACGATACCCCGTGGCCCTACCATGCGGGTACCCAGTCTTCGCTTCCGCCATATCGTTGTTCGCTATGGCG
GCCAGGTCAATGCCGTCCCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MSSVKHSPNDQDRAPGEVSTVQRALNLLKLLGTTEKPIGVNEIARRLGKHVSAVSRTLATLEHNGFVERDEETGRFVLGV
ELIALASRLLAEHDVVRVARPYLEELAESTRETTSLSLWNKTHAINVEHVLGPGSIKHIAAPGRRNPAHCTATGKAMLSH
MPDSTLREVLALGLERYTDRTTTEVSALESELDHIRKQGYALNVGEFIPEIAAVAAVIHDRRGRVAAAIAVTMPVFHFTQ
QIEQQLAPLVINAAAAISKRLGYHSAQPI

Sequences:

>Translated_269_residues
MSSVKHSPNDQDRAPGEVSTVQRALNLLKLLGTTEKPIGVNEIARRLGKHVSAVSRTLATLEHNGFVERDEETGRFVLGV
ELIALASRLLAEHDVVRVARPYLEELAESTRETTSLSLWNKTHAINVEHVLGPGSIKHIAAPGRRNPAHCTATGKAMLSH
MPDSTLREVLALGLERYTDRTTTEVSALESELDHIRKQGYALNVGEFIPEIAAVAAVIHDRRGRVAAAIAVTMPVFHFTQ
QIEQQLAPLVINAAAAISKRLGYHSAQPI
>Mature_268_residues
SSVKHSPNDQDRAPGEVSTVQRALNLLKLLGTTEKPIGVNEIARRLGKHVSAVSRTLATLEHNGFVERDEETGRFVLGVE
LIALASRLLAEHDVVRVARPYLEELAESTRETTSLSLWNKTHAINVEHVLGPGSIKHIAAPGRRNPAHCTATGKAMLSHM
PDSTLREVLALGLERYTDRTTTEVSALESELDHIRKQGYALNVGEFIPEIAAVAAVIHDRRGRVAAAIAVTMPVFHFTQQ
IEQQLAPLVINAAAAISKRLGYHSAQPI

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=257, Percent_Identity=29.9610894941634, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1786468, Length=255, Percent_Identity=26.6666666666667, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87082359, Length=252, Percent_Identity=26.1904761904762, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1786715, Length=243, Percent_Identity=25.9259259259259, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1789999, Length=254, Percent_Identity=27.9527559055118, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788581, Length=250, Percent_Identity=26, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 29335; Mature: 29204

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSVKHSPNDQDRAPGEVSTVQRALNLLKLLGTTEKPIGVNEIARRLGKHVSAVSRTLAT
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LEHNGFVERDEETGRFVLGVELIALASRLLAEHDVVRVARPYLEELAESTRETTSLSLWN
HHHCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
KTHAINVEHVLGPGSIKHIAAPGRRNPAHCTATGKAMLSHMPDSTLREVLALGLERYTDR
CCEEECHHHEECCCCHHHCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
TTTEVSALESELDHIRKQGYALNVGEFIPEIAAVAAVIHDRRGRVAAAIAVTMPVFHFTQ
HHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
QIEQQLAPLVINAAAAISKRLGYHSAQPI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SSVKHSPNDQDRAPGEVSTVQRALNLLKLLGTTEKPIGVNEIARRLGKHVSAVSRTLAT
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LEHNGFVERDEETGRFVLGVELIALASRLLAEHDVVRVARPYLEELAESTRETTSLSLWN
HHHCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
KTHAINVEHVLGPGSIKHIAAPGRRNPAHCTATGKAMLSHMPDSTLREVLALGLERYTDR
CCEEECHHHEECCCCHHHCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
TTTEVSALESELDHIRKQGYALNVGEFIPEIAAVAAVIHDRRGRVAAAIAVTMPVFHFTQ
HHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
QIEQQLAPLVINAAAAISKRLGYHSAQPI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]