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The map label for this gene is mocR [H]

Identifier: 13475156

GI number: 13475156

Start: 4993981

End: 4995450

Strand: Direct

Name: mocR [H]

Synonym: mlr6174

Alternate gene names: 13475156

Gene position: 4993981-4995450 (Clockwise)

Preceding gene: 13475154

Following gene: 13475157

Centisome position: 70.98

GC content: 64.29

Gene sequence:

>1470_bases
ATGGTCCAGTCTCCAGGTCCCGGTGCTTCAACCCGCTCGCATGGCATGGGCGCGCGCCAGATCTACGAAGCGCTTCGCGA
GCAGATCCTCAGAGGCGTTTACGGCACCGGAAGCCAGCTGCCGTCCTCCCGTGGTCTCGCCGAGGAACTTGGCGTCTCGC
GAACGACCGTCACCGTCGCCTACGAGCAGCTGGCCGCGGAAGGTTTCATCGACATCCGTCAAGGCGCGCGCCCTCGTGTC
GCATCCTCACTGCTGGGACATGAGCTGACCGCCAATCCCCCAAAACGGTTCGGCCCGGTTCACTTGTCAAGCTATGGCGA
ACGGCTGCGTGGTACTCCGCGCTGGCCGGATTACCTGCCGAACACGCTGAAGGTTGATTTCCGATATGGCGTCCTGGCGC
CCTCAGATTTCCCCGCATCGGTTTGGAAGCGCGCGATGAACGCGGCGATGGCGCAGCGGCCGGCACGGCTCGCCTATGAC
GATCCGTGCGGTTCGAGCCGGCTCCGCCAAGCGCTTCAGGGCTATCTCTGGCGCGCCCGTACTGTGCGCTGCGACCCCGA
GCAGATCGTCATCGTCAATGGTTCGCAGCAGGGCCTCGATCTCTGCGCGCGCCTGCTGCTCGACCCCGGGGACAGCTTCG
TCATCGAGGACCCCTGCTACAGGATGGCGCGCCAGGTCTTTGCCAGTACAGGTGCCACGCCCGTTCCCGTCGAGGTTGAC
GATCACGGCATGCAAACGGAGCAACTGGCGGGGGTCGCGGCCCGGCTGGCCTATGTGACGCCCTCGCATCAGTTTCCGCT
CGGCGGCGTCATGCCGATCCCGCGGCGGCATCAGCTTCTGGAATGGGCGCGGGAGCAGGGCGCCTATGTCATCGAGGACG
ACTACGACAGCGAATATCGCTACGATATCAGCCCCGTTCCCCCGCTGCATAGCCTCGAGGATCATGGGGCCGTCATCTAC
CTCGGCACCATCTCCAAGACGCTCTCGCCGATGCTGCGGATCGGTTATCTCGTCGTCCCGGCGGAATTCCTGCAGGTTTT
CGAAACCGCCAAGCAGCTTGCCGACCGGCATTCTCCGATGGCGGGGCAGGAGTCATTGGCCTCTCTGATCGAGAGCGGTG
GCTATGAAAGCCATGTGCGCCGCGTGCGCCGCATCAACGGCGAGCGCCGGGAGGCATTGCTGACCGCCCTGAAGCGGAGT
TTTCAAGGTCGGATCGCCGTCCAGGGGGCAGAGGCTGGACTGCACGTCGTCATATGGTTCAACGACCTGCCGCGATCGCG
TGAAACGGCGTTGGTCGAAGCTGCCCAATACGCGGGTCTGGGTCTGCACCCGATTTCGCCGCTTTATCATCGGCAGTCGG
GAGCAGGCGAAGCCGACCGCGTCGGGCTTGTCATGGGCTATTCCGCCCTGAGCATCCGGCAGATCGAAAAAGGCGTCGAG
ATGCTGCGCGACGTCGTCGCTCGACTCTGA

Upstream 100 bases:

>100_bases
TGGATTGCGGTCTCGGGCATCGGCTTCAGACGTGCCTTGGCTTTCGGAAGGAGTGGCTGCAAACTGGTTGATATGGAATG
TCCAGTTGGCAGGAAAAGAA

Downstream 100 bases:

>100_bases
GACGCTGACGGTTCCGCACGCGGGTTAGAACGCATTCGCGGCCGCTCATCGTAAACTGTTCATCGTTGAAATAGTCGCGC
GGCCGGGCGACGGCCGCGCT

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 489; Mature: 489

Protein sequence:

>489_residues
MVQSPGPGASTRSHGMGARQIYEALREQILRGVYGTGSQLPSSRGLAEELGVSRTTVTVAYEQLAAEGFIDIRQGARPRV
ASSLLGHELTANPPKRFGPVHLSSYGERLRGTPRWPDYLPNTLKVDFRYGVLAPSDFPASVWKRAMNAAMAQRPARLAYD
DPCGSSRLRQALQGYLWRARTVRCDPEQIVIVNGSQQGLDLCARLLLDPGDSFVIEDPCYRMARQVFASTGATPVPVEVD
DHGMQTEQLAGVAARLAYVTPSHQFPLGGVMPIPRRHQLLEWAREQGAYVIEDDYDSEYRYDISPVPPLHSLEDHGAVIY
LGTISKTLSPMLRIGYLVVPAEFLQVFETAKQLADRHSPMAGQESLASLIESGGYESHVRRVRRINGERREALLTALKRS
FQGRIAVQGAEAGLHVVIWFNDLPRSRETALVEAAQYAGLGLHPISPLYHRQSGAGEADRVGLVMGYSALSIRQIEKGVE
MLRDVVARL

Sequences:

>Translated_489_residues
MVQSPGPGASTRSHGMGARQIYEALREQILRGVYGTGSQLPSSRGLAEELGVSRTTVTVAYEQLAAEGFIDIRQGARPRV
ASSLLGHELTANPPKRFGPVHLSSYGERLRGTPRWPDYLPNTLKVDFRYGVLAPSDFPASVWKRAMNAAMAQRPARLAYD
DPCGSSRLRQALQGYLWRARTVRCDPEQIVIVNGSQQGLDLCARLLLDPGDSFVIEDPCYRMARQVFASTGATPVPVEVD
DHGMQTEQLAGVAARLAYVTPSHQFPLGGVMPIPRRHQLLEWAREQGAYVIEDDYDSEYRYDISPVPPLHSLEDHGAVIY
LGTISKTLSPMLRIGYLVVPAEFLQVFETAKQLADRHSPMAGQESLASLIESGGYESHVRRVRRINGERREALLTALKRS
FQGRIAVQGAEAGLHVVIWFNDLPRSRETALVEAAQYAGLGLHPISPLYHRQSGAGEADRVGLVMGYSALSIRQIEKGVE
MLRDVVARL
>Mature_489_residues
MVQSPGPGASTRSHGMGARQIYEALREQILRGVYGTGSQLPSSRGLAEELGVSRTTVTVAYEQLAAEGFIDIRQGARPRV
ASSLLGHELTANPPKRFGPVHLSSYGERLRGTPRWPDYLPNTLKVDFRYGVLAPSDFPASVWKRAMNAAMAQRPARLAYD
DPCGSSRLRQALQGYLWRARTVRCDPEQIVIVNGSQQGLDLCARLLLDPGDSFVIEDPCYRMARQVFASTGATPVPVEVD
DHGMQTEQLAGVAARLAYVTPSHQFPLGGVMPIPRRHQLLEWAREQGAYVIEDDYDSEYRYDISPVPPLHSLEDHGAVIY
LGTISKTLSPMLRIGYLVVPAEFLQVFETAKQLADRHSPMAGQESLASLIESGGYESHVRRVRRINGERREALLTALKRS
FQGRIAVQGAEAGLHVVIWFNDLPRSRETALVEAAQYAGLGLHPISPLYHRQSGAGEADRVGLVMGYSALSIRQIEKGVE
MLRDVVARL

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=343, Percent_Identity=24.198250728863, Blast_Score=93, Evalue=6e-19,
Organism=Homo sapiens, GI33469970, Length=343, Percent_Identity=24.198250728863, Blast_Score=93, Evalue=6e-19,
Organism=Escherichia coli, GI1787710, Length=416, Percent_Identity=26.4423076923077, Blast_Score=121, Evalue=8e-29,
Organism=Escherichia coli, GI1790797, Length=424, Percent_Identity=25.4716981132075, Blast_Score=108, Evalue=5e-25,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 53900; Mature: 53900

Theoretical pI: Translated: 8.30; Mature: 8.30

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQSPGPGASTRSHGMGARQIYEALREQILRGVYGTGSQLPSSRGLAEELGVSRTTVTVA
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCHHHHHHH
YEQLAAEGFIDIRQGARPRVASSLLGHELTANPPKRFGPVHLSSYGERLRGTPRWPDYLP
HHHHHHHCCHHHHCCCCHHHHHHHHCCCCCCCCCHHCCCCCHHHHHHHHCCCCCCCCCCC
NTLKVDFRYGVLAPSDFPASVWKRAMNAAMAQRPARLAYDDPCGSSRLRQALQGYLWRAR
CCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHC
TVRCDPEQIVIVNGSQQGLDLCARLLLDPGDSFVIEDPCYRMARQVFASTGATPVPVEVD
EEECCCCEEEEECCCCHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHCCCCCCEEEEC
DHGMQTEQLAGVAARLAYVTPSHQFPLGGVMPIPRRHQLLEWAREQGAYVIEDDYDSEYR
CCCCCHHHHHHHHHHHHEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCEE
YDISPVPPLHSLEDHGAVIYLGTISKTLSPMLRIGYLVVPAEFLQVFETAKQLADRHSPM
ECCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AGQESLASLIESGGYESHVRRVRRINGERREALLTALKRSFQGRIAVQGAEAGLHVVIWF
CCHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCEEEEEECCCCEEEEEEE
NDLPRSRETALVEAAQYAGLGLHPISPLYHRQSGAGEADRVGLVMGYSALSIRQIEKGVE
CCCCCCHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHH
MLRDVVARL
HHHHHHHCC
>Mature Secondary Structure
MVQSPGPGASTRSHGMGARQIYEALREQILRGVYGTGSQLPSSRGLAEELGVSRTTVTVA
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCHHHHHHH
YEQLAAEGFIDIRQGARPRVASSLLGHELTANPPKRFGPVHLSSYGERLRGTPRWPDYLP
HHHHHHHCCHHHHCCCCHHHHHHHHCCCCCCCCCHHCCCCCHHHHHHHHCCCCCCCCCCC
NTLKVDFRYGVLAPSDFPASVWKRAMNAAMAQRPARLAYDDPCGSSRLRQALQGYLWRAR
CCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHC
TVRCDPEQIVIVNGSQQGLDLCARLLLDPGDSFVIEDPCYRMARQVFASTGATPVPVEVD
EEECCCCEEEEECCCCHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHCCCCCCEEEEC
DHGMQTEQLAGVAARLAYVTPSHQFPLGGVMPIPRRHQLLEWAREQGAYVIEDDYDSEYR
CCCCCHHHHHHHHHHHHEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCEE
YDISPVPPLHSLEDHGAVIYLGTISKTLSPMLRIGYLVVPAEFLQVFETAKQLADRHSPM
ECCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AGQESLASLIESGGYESHVRRVRRINGERREALLTALKRSFQGRIAVQGAEAGLHVVIWF
CCHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCEEEEEECCCCEEEEEEE
NDLPRSRETALVEAAQYAGLGLHPISPLYHRQSGAGEADRVGLVMGYSALSIRQIEKGVE
CCCCCCHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHH
MLRDVVARL
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]