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The map label for this gene is ygjG [C]

Identifier: 13475095

GI number: 13475095

Start: 4939089

End: 4940495

Strand: Direct

Name: ygjG [C]

Synonym: mlr6101

Alternate gene names: 13475095

Gene position: 4939089-4940495 (Clockwise)

Preceding gene: 13475094

Following gene: 13475096

Centisome position: 70.2

GC content: 58.0

Gene sequence:

>1407_bases
ATGCGGTTGAGCAATCTGGGAACCGAGCAACTCAGAGAGAAGGATCGAAGCTTCGTCTTTCATCCGTCCACGCATCTGGC
CAAGCACAGCCGAGGCGAGACCCCAAATCGGATCATGGCCGGTGCGGAAGGCGTGTACATCTGGGATACCGAAGGCCGAA
AGAGCCTCGACGGTTTCGGTGGGCTCTACTGCGTCAATATGGGATATGGCTGCACGGAAATTGCCGAGGCCATTGCCAGG
CAAGCACACGAATTGCCGTTCGCCCATGTCTATGCAAGTCAAGGAACAGAGCCAGTCGCCCTCTTGGCAGAGGCCGTCGT
CGAATATTTTGGCCAGAACATGCGAAGGGTCTTTTTCGGCCTTTCCGGCTCCGACGCCAACGAAACCAACATCAAGCTGG
TCTGGTACTACAACAACATTCTGGGCCGCCCCGAAAAGAAGAAGATCATCTCGCGACATCGCGGTTATCATGGGTCTGGG
CTGGTCACCGGGAGCCTGACAGGCCTTGCCTTCTTCCATAATTTCTTCGACCTGCCGCTCGATTTGGTGCGCCATACCAC
GACGCCGCACCACTATCGCCAGGCGCATGACGGCGAAAGTGAGCAAGCGTTCTCGACACGCTGCGCGGATGAACTTGAAG
GCCTTATCCTCGCTGAAGGCCCGGAGACCGTCGCAGCTTTTATCGGCGAGCCGGTGCTTGGGACAGGCGGTATCGTTCCA
CCCCCAAAAGGATACTGGACCGCGATCCAAGGCGTGCTCGACAAGTACGATATCCTGCTGATCGCCGACGAGGTGGTCTG
CGGGTTTGGACGAACCGGTGAGCAATTCGGTTCCCACCTCTATGGCATGCGGCCGGACTTCGTGACCATCGCCAAGGGTT
TGAGTTCCGCCTACCTGCCCATCTCCGGGTCAATCATTGGCGACCGCGTCTGGTCGGTCTTGGAACAAGGAACAGAGAAG
CACGGCGCTCTCGGCCACGGCTGGACATATTCAGGTCACACGCTTTGCGCTGCGGCCGCGCTCGCCAATATTCGACTCCT
AAAGGAAAGAAATATCCTGGAGCATGTCCGCGATGTCGGACCGTATTGGCATGCCCGTATGAATGCCGAACTGGCGGGAC
ACCCCATCGTCGGAGAGGTTCGTGGTGTCGGAATCCTCGCCGCCGTAGAGCTGATGCGAGATCCAAAGCAGAGAATACCG
TTTGAATCCGATCTTCAGGTCGGCGTTCGCGCCGCCGCTGCTCTGTTCGAGAATGGTGTCATCGGCCGTGCCATGCCACA
CGGCGATATCCTCGGCTTTGCCCCGCCTTTGATCATCACCCGTAAGGAGATCGACATAATCGTCGACGCAACCGCGAAAT
CAGTCGAGACGACCTATCGCGCGCTGAAGGCCGAGGGTGCGATATGA

Upstream 100 bases:

>100_bases
GTGCATTCCCGCGAAACTCAAAAGGCTGTTGCGGTATGCTTATTGCTAAGGAAGCGGCCGGCCGAGTGCCCTCCGCCAAT
CCATCGCGAGGAGAGGGACT

Downstream 100 bases:

>100_bases
ACATGCGAGTGCCGACGGAAGCGACCCCCGGGTTCGACGCCGTCCCGGGTAAAGTGGTCCTTGGGAGGAACTTCCAACGG
ACCAAACGCTTTGACGTCAG

Product: hypothetical protein

Products: L-Glutamate; L-Glutamate 5-semialdehyde [C]

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MRLSNLGTEQLREKDRSFVFHPSTHLAKHSRGETPNRIMAGAEGVYIWDTEGRKSLDGFGGLYCVNMGYGCTEIAEAIAR
QAHELPFAHVYASQGTEPVALLAEAVVEYFGQNMRRVFFGLSGSDANETNIKLVWYYNNILGRPEKKKIISRHRGYHGSG
LVTGSLTGLAFFHNFFDLPLDLVRHTTTPHHYRQAHDGESEQAFSTRCADELEGLILAEGPETVAAFIGEPVLGTGGIVP
PPKGYWTAIQGVLDKYDILLIADEVVCGFGRTGEQFGSHLYGMRPDFVTIAKGLSSAYLPISGSIIGDRVWSVLEQGTEK
HGALGHGWTYSGHTLCAAAALANIRLLKERNILEHVRDVGPYWHARMNAELAGHPIVGEVRGVGILAAVELMRDPKQRIP
FESDLQVGVRAAAALFENGVIGRAMPHGDILGFAPPLIITRKEIDIIVDATAKSVETTYRALKAEGAI

Sequences:

>Translated_468_residues
MRLSNLGTEQLREKDRSFVFHPSTHLAKHSRGETPNRIMAGAEGVYIWDTEGRKSLDGFGGLYCVNMGYGCTEIAEAIAR
QAHELPFAHVYASQGTEPVALLAEAVVEYFGQNMRRVFFGLSGSDANETNIKLVWYYNNILGRPEKKKIISRHRGYHGSG
LVTGSLTGLAFFHNFFDLPLDLVRHTTTPHHYRQAHDGESEQAFSTRCADELEGLILAEGPETVAAFIGEPVLGTGGIVP
PPKGYWTAIQGVLDKYDILLIADEVVCGFGRTGEQFGSHLYGMRPDFVTIAKGLSSAYLPISGSIIGDRVWSVLEQGTEK
HGALGHGWTYSGHTLCAAAALANIRLLKERNILEHVRDVGPYWHARMNAELAGHPIVGEVRGVGILAAVELMRDPKQRIP
FESDLQVGVRAAAALFENGVIGRAMPHGDILGFAPPLIITRKEIDIIVDATAKSVETTYRALKAEGAI
>Mature_468_residues
MRLSNLGTEQLREKDRSFVFHPSTHLAKHSRGETPNRIMAGAEGVYIWDTEGRKSLDGFGGLYCVNMGYGCTEIAEAIAR
QAHELPFAHVYASQGTEPVALLAEAVVEYFGQNMRRVFFGLSGSDANETNIKLVWYYNNILGRPEKKKIISRHRGYHGSG
LVTGSLTGLAFFHNFFDLPLDLVRHTTTPHHYRQAHDGESEQAFSTRCADELEGLILAEGPETVAAFIGEPVLGTGGIVP
PPKGYWTAIQGVLDKYDILLIADEVVCGFGRTGEQFGSHLYGMRPDFVTIAKGLSSAYLPISGSIIGDRVWSVLEQGTEK
HGALGHGWTYSGHTLCAAAALANIRLLKERNILEHVRDVGPYWHARMNAELAGHPIVGEVRGVGILAAVELMRDPKQRIP
FESDLQVGVRAAAALFENGVIGRAMPHGDILGFAPPLIITRKEIDIIVDATAKSVETTYRALKAEGAI

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=415, Percent_Identity=27.2289156626506, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI13994255, Length=423, Percent_Identity=24.822695035461, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI226442705, Length=417, Percent_Identity=23.7410071942446, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI37574042, Length=423, Percent_Identity=24.113475177305, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI284507298, Length=308, Percent_Identity=28.2467532467532, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI226442709, Length=364, Percent_Identity=25.2747252747253, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI24119277, Length=443, Percent_Identity=25.0564334085779, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI145693181, Length=412, Percent_Identity=27.1844660194175, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1788044, Length=415, Percent_Identity=28.6746987951807, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1789759, Length=404, Percent_Identity=26.7326732673267, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1789016, Length=406, Percent_Identity=26.6009852216749, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI1787560, Length=416, Percent_Identity=28.3653846153846, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1786991, Length=451, Percent_Identity=24.8337028824834, Blast_Score=99, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI32564660, Length=452, Percent_Identity=27.8761061946903, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI25144271, Length=451, Percent_Identity=25.0554323725055, Blast_Score=144, Evalue=8e-35,
Organism=Caenorhabditis elegans, GI71992977, Length=423, Percent_Identity=26.7139479905437, Blast_Score=125, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI25144274, Length=283, Percent_Identity=28.6219081272085, Blast_Score=124, Evalue=7e-29,
Organism=Saccharomyces cerevisiae, GI6323470, Length=428, Percent_Identity=27.803738317757, Blast_Score=139, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6324432, Length=421, Percent_Identity=25.1781472684086, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6324386, Length=478, Percent_Identity=23.6401673640167, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI28574759, Length=436, Percent_Identity=27.5229357798165, Blast_Score=142, Evalue=4e-34,
Organism=Drosophila melanogaster, GI161085790, Length=434, Percent_Identity=26.4976958525346, Blast_Score=139, Evalue=4e-33,
Organism=Drosophila melanogaster, GI21357415, Length=436, Percent_Identity=27.7522935779816, Blast_Score=136, Evalue=4e-32,
Organism=Drosophila melanogaster, GI21356575, Length=417, Percent_Identity=23.2613908872902, Blast_Score=105, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: 2.6.1.13 [C]

Molecular weight: Translated: 51124; Mature: 51124

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLSNLGTEQLREKDRSFVFHPSTHLAKHSRGETPNRIMAGAEGVYIWDTEGRKSLDGFG
CCCCCCCHHHHHHHCCCEEECCCHHHHHHCCCCCCCHHHCCCCEEEEECCCCCCCCCCCC
GLYCVNMGYGCTEIAEAIARQAHELPFAHVYASQGTEPVALLAEAVVEYFGQNMRRVFFG
CEEEEECCCCHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHEE
LSGSDANETNIKLVWYYNNILGRPEKKKIISRHRGYHGSGLVTGSLTGLAFFHNFFDLPL
CCCCCCCCCEEEEEEEECCHHCCCHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHCHH
DLVRHTTTPHHYRQAHDGESEQAFSTRCADELEGLILAEGPETVAAFIGEPVLGTGGIVP
HHHHCCCCCHHHHHCCCCCCHHHHHHHHHHHHCCEEEECCHHHHHHHHCCCCCCCCCCCC
PPKGYWTAIQGVLDKYDILLIADEVVCGFGRTGEQFGSHLYGMRPDFVTIAKGLSSAYLP
CCCHHHHHHHHHHHHCCEEEEECHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHCCCCCCC
ISGSIIGDRVWSVLEQGTEKHGALGHGWTYSGHTLCAAAALANIRLLKERNILEHVRDVG
CCCCHHHHHHHHHHHHCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PYWHARMNAELAGHPIVGEVRGVGILAAVELMRDPKQRIPFESDLQVGVRAAAALFENGV
CHHHHCCCCCCCCCCCCHHHCCCHHHHHHHHHHCHHHHCCCCCCHHHHHHHHHHHHHCCC
IGRAMPHGDILGFAPPLIITRKEIDIIVDATAKSVETTYRALKAEGAI
CCCCCCCCCCCCCCCCEEEEECCEEEEEECCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRLSNLGTEQLREKDRSFVFHPSTHLAKHSRGETPNRIMAGAEGVYIWDTEGRKSLDGFG
CCCCCCCHHHHHHHCCCEEECCCHHHHHHCCCCCCCHHHCCCCEEEEECCCCCCCCCCCC
GLYCVNMGYGCTEIAEAIARQAHELPFAHVYASQGTEPVALLAEAVVEYFGQNMRRVFFG
CEEEEECCCCHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHEE
LSGSDANETNIKLVWYYNNILGRPEKKKIISRHRGYHGSGLVTGSLTGLAFFHNFFDLPL
CCCCCCCCCEEEEEEEECCHHCCCHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHCHH
DLVRHTTTPHHYRQAHDGESEQAFSTRCADELEGLILAEGPETVAAFIGEPVLGTGGIVP
HHHHCCCCCHHHHHCCCCCCHHHHHHHHHHHHCCEEEECCHHHHHHHHCCCCCCCCCCCC
PPKGYWTAIQGVLDKYDILLIADEVVCGFGRTGEQFGSHLYGMRPDFVTIAKGLSSAYLP
CCCHHHHHHHHHHHHCCEEEEECHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHCCCCCCC
ISGSIIGDRVWSVLEQGTEKHGALGHGWTYSGHTLCAAAALANIRLLKERNILEHVRDVG
CCCCHHHHHHHHHHHHCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PYWHARMNAELAGHPIVGEVRGVGILAAVELMRDPKQRIPFESDLQVGVRAAAALFENGV
CHHHHCCCCCCCCCCCCHHHCCCHHHHHHHHHHCHHHHCCCCCCHHHHHHHHHHHHHCCC
IGRAMPHGDILGFAPPLIITRKEIDIIVDATAKSVETTYRALKAEGAI
CCCCCCCCCCCCCCCCEEEEECCEEEEEECCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; Ornithine [C]

Specific reaction: 2-Oxoglutarate + Ornithine --> L-Glutamate + L-Glutamate 5-semialdehyde [C]

General reaction: Amino group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8796346; 9163424 [H]