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The map label for this gene is tauD [C]

Identifier: 13475013

GI number: 13475013

Start: 4851864

End: 4852751

Strand: Reverse

Name: tauD [C]

Synonym: mll5998

Alternate gene names: 13475013

Gene position: 4852751-4851864 (Counterclockwise)

Preceding gene: 13475014

Following gene: 13475011

Centisome position: 68.97

GC content: 55.41

Gene sequence:

>888_bases
ATGAGTGAAATGGACTTGATCGATAATGTCATCCCACGTAGGGATGTAATCAAATGCACAGCGCGTATCGGTGCTGAAAT
CAGGAATGTCAAGCTTTCGGCCGATTTGCCGGACCGGACCATCGCTGCCATAAACGGCTTGGTGCTTGAGCACAAGGTCG
TCTTCTTCCGCGACCAGGGTCATCTCGACGACGCTGGGCAGGAGCGTTTTGCTCTGCGATTCGGGAAGCTGTCGCCGTAT
CCGGAGGGAACGACGCCGATTTACGACATTGATACCGCACGTGGAGATACCGGGGCTTACGTTTGGCATATCGATTGGTC
CTGCATGGACGCTTATCCCAAGATTGCGGTGCTGCGAGGCGTTACGATACCGCTAGTCGGTGGCGACACCGTCTGGTCAA
ACACCGCGGCCGCATATCTCGACTTACCGTTGCCGCTGCAACGGCTTGCCAACGAACTCTGGGCTGTTCACAGCTTCCCC
GGATCTTATCTCAGGTCTTCTACCGAGCCCAATACTGGACCGATGATCGAGACAGAGCATCCAGTCGTACGCGTCCACCC
CGAGACCGGGGAGCGCACGCTTGTGCTCGGCGTTTATGTAACGCGTTTCGTTGGCATATCCAAATATGACGGCCAAAGGC
TACTCGATCTCTTTGAGTCTCATGTCACCGCGCAGGAAAACACGGTACGCTGGAAGTGGAAGGAGGGTGATATCGCTATC
TGGGACAATCGAGCAACGATGCATTGTGCAACCAAGGATTGCGGCGACCAACGCCGCGTCGTTCGTCGCGCAACCATTGA
GGGCGAGGTGCCCGTCAGTGTCGACGGCCGGTACAGTGTTGTGCGATCTAAATTTATCCAGTCGACCGTGAACAATCTTG
ATCGCTAA

Upstream 100 bases:

>100_bases
CGAGATCAGCCTACCAGGAGTGGTAGGTGCGGTTCGCAATAATATGAAATACTACCAGTTGCGCATAGCCAACAAAACTG
CAGCATCGGAGAATGCCACC

Downstream 100 bases:

>100_bases
GCGGCAAGCTGCTTCGGCCGGTTCAGGAACGCGGCGATCAAGAGCCACAAAAGCGTCTTCAGCCACCTGAGCAGGAGGGA
GAAGTTGTAGCCGGCTGCTG

Product: hypothetical protein

Products: Aminoacetaldehyde; CO2; H+; Sulfite; Succinate [C]

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MSEMDLIDNVIPRRDVIKCTARIGAEIRNVKLSADLPDRTIAAINGLVLEHKVVFFRDQGHLDDAGQERFALRFGKLSPY
PEGTTPIYDIDTARGDTGAYVWHIDWSCMDAYPKIAVLRGVTIPLVGGDTVWSNTAAAYLDLPLPLQRLANELWAVHSFP
GSYLRSSTEPNTGPMIETEHPVVRVHPETGERTLVLGVYVTRFVGISKYDGQRLLDLFESHVTAQENTVRWKWKEGDIAI
WDNRATMHCATKDCGDQRRVVRRATIEGEVPVSVDGRYSVVRSKFIQSTVNNLDR

Sequences:

>Translated_295_residues
MSEMDLIDNVIPRRDVIKCTARIGAEIRNVKLSADLPDRTIAAINGLVLEHKVVFFRDQGHLDDAGQERFALRFGKLSPY
PEGTTPIYDIDTARGDTGAYVWHIDWSCMDAYPKIAVLRGVTIPLVGGDTVWSNTAAAYLDLPLPLQRLANELWAVHSFP
GSYLRSSTEPNTGPMIETEHPVVRVHPETGERTLVLGVYVTRFVGISKYDGQRLLDLFESHVTAQENTVRWKWKEGDIAI
WDNRATMHCATKDCGDQRRVVRRATIEGEVPVSVDGRYSVVRSKFIQSTVNNLDR
>Mature_294_residues
SEMDLIDNVIPRRDVIKCTARIGAEIRNVKLSADLPDRTIAAINGLVLEHKVVFFRDQGHLDDAGQERFALRFGKLSPYP
EGTTPIYDIDTARGDTGAYVWHIDWSCMDAYPKIAVLRGVTIPLVGGDTVWSNTAAAYLDLPLPLQRLANELWAVHSFPG
SYLRSSTEPNTGPMIETEHPVVRVHPETGERTLVLGVYVTRFVGISKYDGQRLLDLFESHVTAQENTVRWKWKEGDIAIW
DNRATMHCATKDCGDQRRVVRRATIEGEVPVSVDGRYSVVRSKFIQSTVNNLDR

Specific function: Catalyzes The Conversion Of Taurine And Alpha Ketoglutarate To Sulfite, Aminoacetaldehyde And Succinate. Required For The Utilization Of Taurine (2-Aminoethanesulfonic Acid) As An Alternative Sulfur Source. Pentane-Sulfonic Acid, 3- (N-Morpholino)Propanes

COG id: COG2175

COG function: function code Q; Probable taurine catabolism dioxygenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tfdA dioxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786565, Length=284, Percent_Identity=35.2112676056338, Blast_Score=155, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6322971, Length=281, Percent_Identity=28.1138790035587, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003819 [H]

Pfam domain/function: PF02668 TauD [H]

EC number: 1.14.11.17 [C]

Molecular weight: Translated: 33162; Mature: 33031

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEMDLIDNVIPRRDVIKCTARIGAEIRNVKLSADLPDRTIAAINGLVLEHKVVFFRDQG
CCCHHHHHHHCCCHHHHHHHHHHCCEEEEEEEECCCCCHHHHHHHCEEEEEEEEEEECCC
HLDDAGQERFALRFGKLSPYPEGTTPIYDIDTARGDTGAYVWHIDWSCMDAYPKIAVLRG
CCCCCCCCEEEEEECCCCCCCCCCCCEEEEECCCCCCCEEEEEEECHHHCCCCCEEEECC
VTIPLVGGDTVWSNTAAAYLDLPLPLQRLANELWAVHSFPGSYLRSSTEPNTGPMIETEH
CEEEEECCCCEECCCCEEEEECCCCHHHHHHHHHHHHCCCHHHHHCCCCCCCCCEEECCC
PVVRVHPETGERTLVLGVYVTRFVGISKYDGQRLLDLFESHVTAQENTVRWKWKEGDIAI
CEEEECCCCCCEEEEEEEHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCEEE
WDNRATMHCATKDCGDQRRVVRRATIEGEVPVSVDGRYSVVRSKFIQSTVNNLDR
ECCCEEEEECCCCCCHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SEMDLIDNVIPRRDVIKCTARIGAEIRNVKLSADLPDRTIAAINGLVLEHKVVFFRDQG
CCHHHHHHHCCCHHHHHHHHHHCCEEEEEEEECCCCCHHHHHHHCEEEEEEEEEEECCC
HLDDAGQERFALRFGKLSPYPEGTTPIYDIDTARGDTGAYVWHIDWSCMDAYPKIAVLRG
CCCCCCCCEEEEEECCCCCCCCCCCCEEEEECCCCCCCEEEEEEECHHHCCCCCEEEECC
VTIPLVGGDTVWSNTAAAYLDLPLPLQRLANELWAVHSFPGSYLRSSTEPNTGPMIETEH
CEEEEECCCCEECCCCEEEEECCCCHHHHHHHHHHHHCCCHHHHHCCCCCCCCCEEECCC
PVVRVHPETGERTLVLGVYVTRFVGISKYDGQRLLDLFESHVTAQENTVRWKWKEGDIAI
CEEEECCCCCCEEEEEEEHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCEEE
WDNRATMHCATKDCGDQRRVVRRATIEGEVPVSVDGRYSVVRSKFIQSTVNNLDR
ECCCEEEEECCCCCCHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Ascorbate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; O2; Taurine [C]

Specific reaction: 2-Oxoglutarate + O2 + Taurine --> Aminoacetaldehyde + CO2 + H+ + Sulfite + Succinate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]