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The map label for this gene is groES

Identifier: 13474838

GI number: 13474838

Start: 4688985

End: 4689281

Strand: Reverse

Name: groES

Synonym: msl5812

Alternate gene names: 13474838

Gene position: 4689281-4688985 (Counterclockwise)

Preceding gene: 13474839

Following gene: 13474837

Centisome position: 66.65

GC content: 60.94

Gene sequence:

>297_bases
ATGGCACAGTCGAATTTGCGGCCGCTTCATGACCGCGTGGTCGTTCGCCGAGTCGAATCCGAATCCAAGACCGCCGGCGG
GATCATCATACCCGACACGGCAAAGGAAAAGCCGCAGGAAGGCGAGATCATCGCCGTCGGTTCCGGCGCCCGCGACGAAG
CCGGCAAGCTCGTTCCGCTGGACGTCAAGGCCGGCGACCGCATCCTGTTCGGCAAGTGGTCGGGCACCGAAGTCAAGCTC
AATGGCGAAGACCTTCTGATCATGAAGGAAGCCGACATCATGGGCATCATCGGCTAA

Upstream 100 bases:

>100_bases
ACAGCCTATCTCACGATCATCTTAGCACTCCCCAATAGCGAGTGCTAACCACCCTCCGGCAACGGAGAACCTTTCAACCT
GCGCACCAGGGATAGTAAAA

Downstream 100 bases:

>100_bases
CACGCCGCTGCCTTTCATCCGTACCATCCAATCTGAATTTCGGGCGAAATGCCCAGGAGTACAAAATGGCTGCCAAAGAC
GTGAAATTCTCTCGTGATGC

Product: co-chaperonin GroES

Products: NA

Alternate protein names: GroES protein 3; Protein Cpn10 3

Number of amino acids: Translated: 98; Mature: 97

Protein sequence:

>98_residues
MAQSNLRPLHDRVVVRRVESESKTAGGIIIPDTAKEKPQEGEIIAVGSGARDEAGKLVPLDVKAGDRILFGKWSGTEVKL
NGEDLLIMKEADIMGIIG

Sequences:

>Translated_98_residues
MAQSNLRPLHDRVVVRRVESESKTAGGIIIPDTAKEKPQEGEIIAVGSGARDEAGKLVPLDVKAGDRILFGKWSGTEVKL
NGEDLLIMKEADIMGIIG
>Mature_97_residues
AQSNLRPLHDRVVVRRVESESKTAGGIIIPDTAKEKPQEGEIIAVGSGARDEAGKLVPLDVKAGDRILFGKWSGTEVKLN
GEDLLIMKEADIMGIIG

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family

Homologues:

Organism=Homo sapiens, GI4504523, Length=94, Percent_Identity=37.2340425531915, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1790585, Length=94, Percent_Identity=47.8723404255319, Blast_Score=91, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17555568, Length=93, Percent_Identity=40.8602150537634, Blast_Score=87, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6324594, Length=92, Percent_Identity=36.9565217391304, Blast_Score=72, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21356029, Length=90, Percent_Identity=41.1111111111111, Blast_Score=76, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21358317, Length=89, Percent_Identity=38.2022471910112, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): CH103_RHILO (Q98AX8)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_106408.1
- ProteinModelPortal:   Q98AX8
- SMR:   Q98AX8
- GeneID:   1229067
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:msl5812
- NMPDR:   fig|266835.1.peg.4511
- HOGENOM:   HBG703377
- OMA:   TELAYEG
- ProtClustDB:   PRK00364
- GO:   GO:0005737
- HAMAP:   MF_00580
- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032
- Gene3D:   G3DSA:2.30.33.40
- PANTHER:   PTHR10772
- PRINTS:   PR00297
- SMART:   SM00883

Pfam domain/function: PF00166 Cpn10; SSF50129 GroES_like

EC number: NA

Molecular weight: Translated: 10507; Mature: 10376

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQSNLRPLHDRVVVRRVESESKTAGGIIIPDTAKEKPQEGEIIAVGSGARDEAGKLVPL
CCCCCCCCCHHHHEEEECCCCCCCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCCEEEE
DVKAGDRILFGKWSGTEVKLNGEDLLIMKEADIMGIIG
ECCCCCEEEEECCCCCEEEECCCEEEEEECCCEEEECC
>Mature Secondary Structure 
AQSNLRPLHDRVVVRRVESESKTAGGIIIPDTAKEKPQEGEIIAVGSGARDEAGKLVPL
CCCCCCCCHHHHEEEECCCCCCCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCCEEEE
DVKAGDRILFGKWSGTEVKLNGEDLLIMKEADIMGIIG
ECCCCCEEEEECCCCCEEEECCCEEEEEECCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968