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The map label for this gene is thiO [H]

Identifier: 13474822

GI number: 13474822

Start: 4670969

End: 4671970

Strand: Reverse

Name: thiO [H]

Synonym: mll5793

Alternate gene names: 13474822

Gene position: 4671970-4670969 (Counterclockwise)

Preceding gene: 13474823

Following gene: 13474821

Centisome position: 66.4

GC content: 65.67

Gene sequence:

>1002_bases
ATGAAGGTGTTGATCAAAGGGGCCGGCGTCGCCGGCCTCACCGCGGCCTTCGAACTCGCCATCCGCGGCGCGGCGGTGAC
GGTTGCCGAGACGAGACTTAGCCTCGGCGGCAATGCGTCGTGGTTCGCGGGCGGCATGTTGGCGCCATGGTGCGAGCGTG
AAAGCGCCGAGCAGCCGGTGCTCGATCTCGGACGCGACGCCGCCGACTGGTGGGATACGGCAACGCCCGGGCAGGTGACG
CGGGCCGGAACACTGGTCGTGGCCGCGCCGCGCGATGCGGGCGAGCTCGACCGGTTTGCCAGTCGCACGTCGGGGTACAG
GCCTTTCGATGAAAACGAAATCGCACAGCTCGAGCCGGACCTCTCCGGTCGTTTCCGCCGTGCGCTGTTCTTCCCCGACG
AAGCCCATCTCGACCCGCGCCGGGCGATGGCTGCACTGCATAACAGGCTGGCGGCGATGGGCGTCGAATTCCGCTTCGGT
GCCGATGCCCGGCACATTTCCGGATTCGATCGCCGGATCGACTGCACGGGGATGGCGGCAGAAGACGATGGGTTGCGCGG
CGTTCGCGGCGAAATGCTGATCCTGCGTACGCCTGATGTCTCGCTGTCGCGCCCGGTCCGTCTGCTTCATCCGCGCTTTC
CGCTCTATGTGGTGCCGCGTGCCGACCACCATTTCATGGTTGGGGCGACGATGATCGAAAGCCAATCCGGGGGACCGGTC
ACGGCGCGTTCGATGATGGAGCTTCTGGGCGCCGCCTATGCCCTCCATCCGGCCTTTGGCGAGGCCGAGATCGTTGAAAC
CGGTGTCGGCATCCGCCCAGCCTTTCCCGACAATCTGCCGCGTGTCGAGGCATGCGGAAGCGCCGTCGCGATCAACGGGC
TTTATCGCCATGGCTTTCTTCTCGCGCCCGCCATGGCGCGCCGGGCGGCCGACCTGGTTTTCAATCAAGACGGAACCAAG
GAGCTTGCTCATGAAACTGTTGGTCAACGGCAAAGCGCATGA

Upstream 100 bases:

>100_bases
GCATGGCGGCGATGGCGGCGAAATACCGCGAGGGCGGCGATCTCTACGTGCCCGCGGAAGAGAGCGGCGCACCGCTCATG
CCGGAGGCGCATGAGCTGTC

Downstream 100 bases:

>100_bases
GGTTGCCGCCACCACCCTGGCCGAGCTGCTTGCAGCGCTCGACTATGAGGGCGATTGGCTGGCGACCGCCGTCAACAGCG
ACCTCGTGCACAAAGCCAGC

Product: thiamine biosynthesis oxidoreductase THIO

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MKVLIKGAGVAGLTAAFELAIRGAAVTVAETRLSLGGNASWFAGGMLAPWCERESAEQPVLDLGRDAADWWDTATPGQVT
RAGTLVVAAPRDAGELDRFASRTSGYRPFDENEIAQLEPDLSGRFRRALFFPDEAHLDPRRAMAALHNRLAAMGVEFRFG
ADARHISGFDRRIDCTGMAAEDDGLRGVRGEMLILRTPDVSLSRPVRLLHPRFPLYVVPRADHHFMVGATMIESQSGGPV
TARSMMELLGAAYALHPAFGEAEIVETGVGIRPAFPDNLPRVEACGSAVAINGLYRHGFLLAPAMARRAADLVFNQDGTK
ELAHETVGQRQSA

Sequences:

>Translated_333_residues
MKVLIKGAGVAGLTAAFELAIRGAAVTVAETRLSLGGNASWFAGGMLAPWCERESAEQPVLDLGRDAADWWDTATPGQVT
RAGTLVVAAPRDAGELDRFASRTSGYRPFDENEIAQLEPDLSGRFRRALFFPDEAHLDPRRAMAALHNRLAAMGVEFRFG
ADARHISGFDRRIDCTGMAAEDDGLRGVRGEMLILRTPDVSLSRPVRLLHPRFPLYVVPRADHHFMVGATMIESQSGGPV
TARSMMELLGAAYALHPAFGEAEIVETGVGIRPAFPDNLPRVEACGSAVAINGLYRHGFLLAPAMARRAADLVFNQDGTK
ELAHETVGQRQSA
>Mature_333_residues
MKVLIKGAGVAGLTAAFELAIRGAAVTVAETRLSLGGNASWFAGGMLAPWCERESAEQPVLDLGRDAADWWDTATPGQVT
RAGTLVVAAPRDAGELDRFASRTSGYRPFDENEIAQLEPDLSGRFRRALFFPDEAHLDPRRAMAALHNRLAAMGVEFRFG
ADARHISGFDRRIDCTGMAAEDDGLRGVRGEMLILRTPDVSLSRPVRLLHPRFPLYVVPRADHHFMVGATMIESQSGGPV
TARSMMELLGAAYALHPAFGEAEIVETGVGIRPAFPDNLPRVEACGSAVAINGLYRHGFLLAPAMARRAADLVFNQDGTK
ELAHETVGQRQSA

Specific function: May have amino acid oxidase activity in the biosynthesis of thiazole when cysteine gives its thiol group to be inserted into the thiazole molecule and the rest of the molecule is deaminated to give pyruvic acid and ammonia [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR012727 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: NA

Molecular weight: Translated: 35913; Mature: 35913

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLIKGAGVAGLTAAFELAIRGAAVTVAETRLSLGGNASWFAGGMLAPWCERESAEQPV
CEEEEECCCCHHHHHHHHHHHCCCEEEEEEHHHHCCCCCCEECCCCCCCHHCCCCCCCCH
LDLGRDAADWWDTATPGQVTRAGTLVVAAPRDAGELDRFASRTSGYRPFDENEIAQLEPD
HHCCCCCHHHCCCCCCCCEEECCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCHHHCCCC
LSGRFRRALFFPDEAHLDPRRAMAALHNRLAAMGVEFRFGADARHISGFDRRIDCTGMAA
CCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCEEEEECCCCHHCCCCCCEEEECCCCC
EDDGLRGVRGEMLILRTPDVSLSRPVRLLHPRFPLYVVPRADHHFMVGATMIESQSGGPV
CCCCCCCCCCCEEEEECCCCCCCCCHHHHCCCCCEEEEECCCCEEEEEEEEEECCCCCCC
TARSMMELLGAAYALHPAFGEAEIVETGVGIRPAFPDNLPRVEACGSAVAINGLYRHGFL
CHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCHHHHCCCEEEECHHHHCCCH
LAPAMARRAADLVFNQDGTKELAHETVGQRQSA
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKVLIKGAGVAGLTAAFELAIRGAAVTVAETRLSLGGNASWFAGGMLAPWCERESAEQPV
CEEEEECCCCHHHHHHHHHHHCCCEEEEEEHHHHCCCCCCEECCCCCCCHHCCCCCCCCH
LDLGRDAADWWDTATPGQVTRAGTLVVAAPRDAGELDRFASRTSGYRPFDENEIAQLEPD
HHCCCCCHHHCCCCCCCCEEECCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCHHHCCCC
LSGRFRRALFFPDEAHLDPRRAMAALHNRLAAMGVEFRFGADARHISGFDRRIDCTGMAA
CCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCEEEEECCCCHHCCCCCCEEEECCCCC
EDDGLRGVRGEMLILRTPDVSLSRPVRLLHPRFPLYVVPRADHHFMVGATMIESQSGGPV
CCCCCCCCCCCEEEEECCCCCCCCCHHHHCCCCCEEEEECCCCEEEEEEEEEECCCCCCC
TARSMMELLGAAYALHPAFGEAEIVETGVGIRPAFPDNLPRVEACGSAVAINGLYRHGFL
CHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCHHHHCCCEEEECHHHHCCCH
LAPAMARRAADLVFNQDGTKELAHETVGQRQSA
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371431 [H]