Click here to switch to the map view.

The map label for this gene is mdtA [H]

Identifier: 13474811

GI number: 13474811

Start: 4662126

End: 4663379

Strand: Reverse

Name: mdtA [H]

Synonym: mll5780

Alternate gene names: 13474811

Gene position: 4663379-4662126 (Counterclockwise)

Preceding gene: 13474813

Following gene: 13474810

Centisome position: 66.28

GC content: 60.53

Gene sequence:

>1254_bases
ATGCTCGAACAGACCCCAGACAAACCGCACGAGCCTTTGGCGCAACAGACCCTTCCCGCTGAGAAGTTCCGCAAGTCGCG
GTCGCTGCGATTAATGTTCGCGATCGTCCTCTTGGGCGGTAGCTCTTTTGCCATCTATGCCTACAGCAGCGCTCGCCCTT
CGGACGCCGTCGCGCTCGCAACTGTCGCACCGGCGCCTCCCATTGTGGTCAAGGCAGCGCAGGCGCAACTTGGGAACGTT
CCGATCTGGGTCACAGGGCTCGGAACCGTGCAACCCTTCAACAGCGTGACAGTCAAGCCTCGCGCCAATGGGCAGATCAA
CGATATCGTCTTCACTGAAGGCCAGATGGTGCATGCGCACGATGTGCTCGCCCGCCTGGACCCGAAACCCTTCCTTGGAC
CTCTGCATCAGGCCGAAGCGACGCTGGCCAAGGATCAGGCACAACTCACCAATGCTCAAGCTGATCTGCAACGCGTTTCG
AGCCTTGCCCAGAAAGGCTTTGCCACGGGCCAGGTCCTCGATACGCAAAAGGCGCAGATCGCCCAGACGGAGGCGACGAT
TTTGGCGGACAAAGCCGCCATCGAGAACGCGCAGACCCAGATAGACTACACCACCATCACCTCGCCGATCGACGGCGTGG
CGGGCATACGGATGATCGATGCGGGCAACATGATCACTTCGACCGATCTGGGGATTGTGACAATCAATCAGCTCGAGCCG
ATTTCGGTCGTGTTTACCGTGCCGGCGGACGCCGTCGCTGACTGGCCGGTCGGAACGCCAGCGTCCGCGATTTCCGTCAC
CGCCCTAGCGGCCAACGATAGCAGGATGCTCGACACGGGAACTTTGAGCCTCGTCGACAATCATATCGATCCCGCGACGG
CTACCATCAAATTGAAGGCGACTTTCCCGAACAAGGACCATCAACTGAAGCCGGGGCAGTTCGTCAGTGCCCTGTTCCAG
AGCGTGCTCCTGTCCGAGGCGACTTCGGTTCCATCAAGTGCCGTTCAGCAGTCGGCCAACGGCACTTACGTCTATCTGGT
CAAGCCGGAGGACTCGACGCTGGTCCAGCGCAAGGTGACGGTCAAACGCGTAGCCGGCGACGTCACCGTGATTGCTTCGG
GCTTGAATGCCGGCGATACGGTCGTCACCGAGGGGCAATACAGCCTGAAGCCCGGGATGAAAGTGTCGACGCAGAGCGCC
GGATCGCAGGACGCGGCAGGCGAAGCTTTGGGCCATCGAAGGGATCGAGTGTGA

Upstream 100 bases:

>100_bases
CACCGATTTTAATAGCGCAAAAGGATTTCCGACGTAATGCTGCAGTGCAACAGAACGGTCTTTGAGCGTGCCGTTTATGC
ACTGTCACCAGGAGATCCGA

Downstream 100 bases:

>100_bases
GCGTCTCCAACATATTCGTCCAGCGTCCAATTGCGACCGGGCTGCTGACGCTCGGCATCGTGCTCGTGGGCATGGTTGCG
TACATGCTTCTGCCGATCTC

Product: RND efflux membrane fusion protein

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MLEQTPDKPHEPLAQQTLPAEKFRKSRSLRLMFAIVLLGGSSFAIYAYSSARPSDAVALATVAPAPPIVVKAAQAQLGNV
PIWVTGLGTVQPFNSVTVKPRANGQINDIVFTEGQMVHAHDVLARLDPKPFLGPLHQAEATLAKDQAQLTNAQADLQRVS
SLAQKGFATGQVLDTQKAQIAQTEATILADKAAIENAQTQIDYTTITSPIDGVAGIRMIDAGNMITSTDLGIVTINQLEP
ISVVFTVPADAVADWPVGTPASAISVTALAANDSRMLDTGTLSLVDNHIDPATATIKLKATFPNKDHQLKPGQFVSALFQ
SVLLSEATSVPSSAVQQSANGTYVYLVKPEDSTLVQRKVTVKRVAGDVTVIASGLNAGDTVVTEGQYSLKPGMKVSTQSA
GSQDAAGEALGHRRDRV

Sequences:

>Translated_417_residues
MLEQTPDKPHEPLAQQTLPAEKFRKSRSLRLMFAIVLLGGSSFAIYAYSSARPSDAVALATVAPAPPIVVKAAQAQLGNV
PIWVTGLGTVQPFNSVTVKPRANGQINDIVFTEGQMVHAHDVLARLDPKPFLGPLHQAEATLAKDQAQLTNAQADLQRVS
SLAQKGFATGQVLDTQKAQIAQTEATILADKAAIENAQTQIDYTTITSPIDGVAGIRMIDAGNMITSTDLGIVTINQLEP
ISVVFTVPADAVADWPVGTPASAISVTALAANDSRMLDTGTLSLVDNHIDPATATIKLKATFPNKDHQLKPGQFVSALFQ
SVLLSEATSVPSSAVQQSANGTYVYLVKPEDSTLVQRKVTVKRVAGDVTVIASGLNAGDTVVTEGQYSLKPGMKVSTQSA
GSQDAAGEALGHRRDRV
>Mature_417_residues
MLEQTPDKPHEPLAQQTLPAEKFRKSRSLRLMFAIVLLGGSSFAIYAYSSARPSDAVALATVAPAPPIVVKAAQAQLGNV
PIWVTGLGTVQPFNSVTVKPRANGQINDIVFTEGQMVHAHDVLARLDPKPFLGPLHQAEATLAKDQAQLTNAQADLQRVS
SLAQKGFATGQVLDTQKAQIAQTEATILADKAAIENAQTQIDYTTITSPIDGVAGIRMIDAGNMITSTDLGIVTINQLEP
ISVVFTVPADAVADWPVGTPASAISVTALAANDSRMLDTGTLSLVDNHIDPATATIKLKATFPNKDHQLKPGQFVSALFQ
SVLLSEATSVPSSAVQQSANGTYVYLVKPEDSTLVQRKVTVKRVAGDVTVIASGLNAGDTVVTEGQYSLKPGMKVSTQSA
GSQDAAGEALGHRRDRV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=338, Percent_Identity=41.4201183431953, Blast_Score=223, Evalue=1e-59,
Organism=Escherichia coli, GI1789929, Length=335, Percent_Identity=31.044776119403, Blast_Score=158, Evalue=6e-40,
Organism=Escherichia coli, GI1786668, Length=320, Percent_Identity=29.6875, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1789665, Length=318, Percent_Identity=28.6163522012579, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI87081951, Length=117, Percent_Identity=31.6239316239316, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 43915; Mature: 43915

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEQTPDKPHEPLAQQTLPAEKFRKSRSLRLMFAIVLLGGSSFAIYAYSSARPSDAVALA
CCCCCCCCCCCCHHHHCCCHHHHHHCCCHHEEEEEEHCCCCCEEEEEECCCCCCCCEEEE
TVAPAPPIVVKAAQAQLGNVPIWVTGLGTVQPFNSVTVKPRANGQINDIVFTEGQMVHAH
EECCCCCEEEEECHHHHCCCCEEEEECCCCCCCCCEEEEECCCCCEEEEEEECCCEEEHH
DVLARLDPKPFLGPLHQAEATLAKDQAQLTNAQADLQRVSSLAQKGFATGQVLDTQKAQI
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCHHHH
AQTEATILADKAAIENAQTQIDYTTITSPIDGVAGIRMIDAGNMITSTDLGIVTINQLEP
HHHHHHHEEHHHHHCCCHHEEEEEEECCCCCCCCCEEEEECCCEEEECCCCEEEECCCCC
ISVVFTVPADAVADWPVGTPASAISVTALAANDSRMLDTGTLSLVDNHIDPATATIKLKA
EEEEEECCCHHHCCCCCCCCCCCEEEEEEECCCCEEEECCEEEEECCCCCCCEEEEEEEE
TFPNKDHQLKPGQFVSALFQSVLLSEATSVPSSAVQQSANGTYVYLVKPEDSTLVQRKVT
ECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCEEEEECCCCCCHHHHHHH
VKRVAGDVTVIASGLNAGDTVVTEGQYSLKPGMKVSTQSAGSQDAAGEALGHRRDRV
HHHHCCCEEEEEECCCCCCEEEECCCEECCCCCEEECCCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MLEQTPDKPHEPLAQQTLPAEKFRKSRSLRLMFAIVLLGGSSFAIYAYSSARPSDAVALA
CCCCCCCCCCCCHHHHCCCHHHHHHCCCHHEEEEEEHCCCCCEEEEEECCCCCCCCEEEE
TVAPAPPIVVKAAQAQLGNVPIWVTGLGTVQPFNSVTVKPRANGQINDIVFTEGQMVHAH
EECCCCCEEEEECHHHHCCCCEEEEECCCCCCCCCEEEEECCCCCEEEEEEECCCEEEHH
DVLARLDPKPFLGPLHQAEATLAKDQAQLTNAQADLQRVSSLAQKGFATGQVLDTQKAQI
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCHHHH
AQTEATILADKAAIENAQTQIDYTTITSPIDGVAGIRMIDAGNMITSTDLGIVTINQLEP
HHHHHHHEEHHHHHCCCHHEEEEEEECCCCCCCCCEEEEECCCEEEECCCCEEEECCCCC
ISVVFTVPADAVADWPVGTPASAISVTALAANDSRMLDTGTLSLVDNHIDPATATIKLKA
EEEEEECCCHHHCCCCCCCCCCCEEEEEEECCCCEEEECCEEEEECCCCCCCEEEEEEEE
TFPNKDHQLKPGQFVSALFQSVLLSEATSVPSSAVQQSANGTYVYLVKPEDSTLVQRKVT
ECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCEEEEECCCCCCHHHHHHH
VKRVAGDVTVIASGLNAGDTVVTEGQYSLKPGMKVSTQSAGSQDAAGEALGHRRDRV
HHHHCCCEEEEEECCCCCCEEEECCCEECCCCCEEECCCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA