Click here to switch to the map view.

The map label for this gene is fur [C]

Identifier: 13474640

GI number: 13474640

Start: 4470848

End: 4471279

Strand: Direct

Name: fur [C]

Synonym: mlr5570

Alternate gene names: 13474640

Gene position: 4470848-4471279 (Clockwise)

Preceding gene: 13474635

Following gene: 13474641

Centisome position: 63.54

GC content: 64.58

Gene sequence:

>432_bases
ATGGACCGGGGCTGCCGGAAGGAAAATGTCGCTGTGGACAAGCGGGTACGTGAAGCCGGCCTGAGGCCGACGCGGCAGCG
CATTGCGCTGGCCGACCTGCTTTTCGCCAAGGGCGATCGCCATCTCTCGGCCGAGGAACTGCACGAGGAGGCGCTGGCCG
CCGGCGTGCCGGTGTCGCTGGCCACGGTCTACAACGCGCTCCACCAGTTCACCCAGGCGGGGCTGCTGCGCATCCTCGCC
GTCGAGGGCGCCAAGACCTATTTCGACACCAACACCTCCGACCACCATCATTTCTACATCGAAGGCGAAAACCGGATTTT
CGACATCGCCAACGGCCCGGTGACAGTCACCAACCTGCCGGATCCGCCCGAGGGCATGGAAATCGCCAATGTCGACATCG
TGGTGAGGCTGCGCCCCAAGCGCCAGGAATGA

Upstream 100 bases:

>100_bases
CGACAGAATATATGTCAACAGGGGTCCGGTTTCGGCAGACATTCATTTTTTTGCCATTCTGGGCATGTCTTGAAGCGGGA
CTGTTGGCTTGGAAGACCAG

Downstream 100 bases:

>100_bases
CCGGCGAGGCCAAGACAATCGGTCCGGCCGGGAATGATCTGTCAGGCCAGAGTACTCTGTCAGGGATGAAGCTCCTCGAC
CGGATAACCCGGCTCGAATG

Product: transcription regulator

Products: NA

Alternate protein names: Ferric Uptake Regulator Fur Family; Transcriptional Regulator Fur Family; FUR Family Transcriptional Regulator; Ferric-Uptake Regulator; Iron Response Regulator; Fe2+/Zn2+ Uptake Regulation Protein; Ferric Uptake Regulator; Fur Family Transcriptional Regulator; Fur Family Ferric Uptake Regulator; Ferric Uptake Regulator FUR Family; Transcriptional Regulator; Ferric Uptake Transcriptional Regulator; Transcriptional Regulator Fur Family Protein; Iron Response Regulator Irr; Transcription Regulator; Iron Transcriptional Regulator Protein

Number of amino acids: Translated: 143; Mature: 143

Protein sequence:

>143_residues
MDRGCRKENVAVDKRVREAGLRPTRQRIALADLLFAKGDRHLSAEELHEEALAAGVPVSLATVYNALHQFTQAGLLRILA
VEGAKTYFDTNTSDHHHFYIEGENRIFDIANGPVTVTNLPDPPEGMEIANVDIVVRLRPKRQE

Sequences:

>Translated_143_residues
MDRGCRKENVAVDKRVREAGLRPTRQRIALADLLFAKGDRHLSAEELHEEALAAGVPVSLATVYNALHQFTQAGLLRILA
VEGAKTYFDTNTSDHHHFYIEGENRIFDIANGPVTVTNLPDPPEGMEIANVDIVVRLRPKRQE
>Mature_143_residues
MDRGCRKENVAVDKRVREAGLRPTRQRIALADLLFAKGDRHLSAEELHEEALAAGVPVSLATVYNALHQFTQAGLLRILA
VEGAKTYFDTNTSDHHHFYIEGENRIFDIANGPVTVTNLPDPPEGMEIANVDIVVRLRPKRQE

Specific function: Acts As A Global Negative Controlling Element, Employing Fe(2+) As A Cofactor To Bind The Operator Of The Repressed Genes. Regulates The Expression Of Several Outer-Membrane Proteins Including The Iron Transport Operon. [C]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 15966; Mature: 15966

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRGCRKENVAVDKRVREAGLRPTRQRIALADLLFAKGDRHLSAEELHEEALAAGVPVSL
CCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHH
ATVYNALHQFTQAGLLRILAVEGAKTYFDTNTSDHHHFYIEGENRIFDIANGPVTVTNLP
HHHHHHHHHHHHHHHHEEEEECCCCEEECCCCCCCEEEEEECCCEEEEECCCCEEECCCC
DPPEGMEIANVDIVVRLRPKRQE
CCCCCCEEECEEEEEEECCCCCC
>Mature Secondary Structure
MDRGCRKENVAVDKRVREAGLRPTRQRIALADLLFAKGDRHLSAEELHEEALAAGVPVSL
CCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHH
ATVYNALHQFTQAGLLRILAVEGAKTYFDTNTSDHHHFYIEGENRIFDIANGPVTVTNLP
HHHHHHHHHHHHHHHHEEEEECCCCEEECCCCCCCEEEEEECCCEEEEECCCCEEECCCC
DPPEGMEIANVDIVVRLRPKRQE
CCCCCCEEECEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA