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The map label for this gene is corA [H]

Identifier: 13474632

GI number: 13474632

Start: 4461041

End: 4462135

Strand: Direct

Name: corA [H]

Synonym: mlr5559

Alternate gene names: 13474632

Gene position: 4461041-4462135 (Clockwise)

Preceding gene: 13474631

Following gene: 13474633

Centisome position: 63.4

GC content: 61.0

Gene sequence:

>1095_bases
ATGGCAAAGGCCGATGCGGTGAAGAGGCGGGCGCCGGCGAAGACGAGGCGGCCGCCCGTCGGCGCCTCGCCGGGCACGCT
GATCGCCGATCCGGCGGCGCGGCGCAGTGAGCTCAGGCTGACGCTGATTTCGCCCGAAAAATTCAAGACCATCGACAATG
CCAGCATCGATGATCTCAATGTCCATTGCGACCGCTGGCCGGTCGTCTGGCTGGATTGCACCGGGCTCGCCAACATCCCG
CTGATCGAGGAGATCGGCCGGATCTTCAACCTGCATCCGCTGGCCCTGGAGGATGTCGTCAACACCGACCAGCGACCGAA
GGTCGATTTCTTCGAGGACCACGCCTTCGTCGTCGTGCGCATGATCGACGATGTCACAGCTCATCGCTACGAGCAGATCG
CCGTGTTCTTCGGTAAGAATTTCGTCGTCACTTTCCAGGAACGCGAGGGAGATCCGTTCGACCCGGTACGCAAGCGTATC
GGGAGTTCGGCGCCCAACCGCCTGCGCACACGCGGCGCCGACTATCTGGCCTACGCGCTGATCGACGCCATCGTCGACAG
CTATTTTCCGCCGGTCGAGGCGGCCGGCGACCAGGTCGACGGCATCGAGGACGAGATGCTGCATTCGACGCACAAGCATC
AGATGCGGCAACTGCACGAATTGCGGCGCGACGCCAATGTGCTGAAGGGCGTGCTGTGGCCGATGCGCGATGCGCTGGCG
ACGCTGATCCGCAACGACGTGCCCTATGTCAAAGCCGAGACCAAGGTTTTCCTCAATGACACACTCGACCATTCGCTCAG
GCTGATCGAGCTGGTTGAGACCCAGCGCGACATGCTGACCGGGCTGATCGAGATGCATCTGTCGCTGAGCCAGGCGCGCA
CCAACGACGTCATCAGCTATCTCACCATCGTCTCGGTCATCTTCATGCCGCTCACCTTCCTGGTCGGCGTCTGGGGCATG
AATTTCAGTCCCGATGCCTCGCCATGGAACATGCCGGAACTGCGATCTTACTATGGTTATCCGGCGGCGCTCGTCTTCAT
GCTGCTTGTCGCGATCGGCCTGATTGCCTTCTTCAAATGGAAAAAATGGCTTTGA

Upstream 100 bases:

>100_bases
CCATCGGCGCGATCGAACAAGGCATGTTCAAGCCCAAGCGGGTCTTTGCCGGGTGACGGCTCTCGTCTAACTTCACGTCG
ATTCTACGATCGAGGGGCAG

Downstream 100 bases:

>100_bases
TAGCGATAAAACTCGGCATTTGGGGCTGAAAAGCCGGCTTGGTGAATTGGGCTGGTGTTTTGCCGGGAATTGCACTATAT
GCGCCGCAGCATAGCGCCTC

Product: divalent cation transport-related protein

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 364; Mature: 363

Protein sequence:

>364_residues
MAKADAVKRRAPAKTRRPPVGASPGTLIADPAARRSELRLTLISPEKFKTIDNASIDDLNVHCDRWPVVWLDCTGLANIP
LIEEIGRIFNLHPLALEDVVNTDQRPKVDFFEDHAFVVVRMIDDVTAHRYEQIAVFFGKNFVVTFQEREGDPFDPVRKRI
GSSAPNRLRTRGADYLAYALIDAIVDSYFPPVEAAGDQVDGIEDEMLHSTHKHQMRQLHELRRDANVLKGVLWPMRDALA
TLIRNDVPYVKAETKVFLNDTLDHSLRLIELVETQRDMLTGLIEMHLSLSQARTNDVISYLTIVSVIFMPLTFLVGVWGM
NFSPDASPWNMPELRSYYGYPAALVFMLLVAIGLIAFFKWKKWL

Sequences:

>Translated_364_residues
MAKADAVKRRAPAKTRRPPVGASPGTLIADPAARRSELRLTLISPEKFKTIDNASIDDLNVHCDRWPVVWLDCTGLANIP
LIEEIGRIFNLHPLALEDVVNTDQRPKVDFFEDHAFVVVRMIDDVTAHRYEQIAVFFGKNFVVTFQEREGDPFDPVRKRI
GSSAPNRLRTRGADYLAYALIDAIVDSYFPPVEAAGDQVDGIEDEMLHSTHKHQMRQLHELRRDANVLKGVLWPMRDALA
TLIRNDVPYVKAETKVFLNDTLDHSLRLIELVETQRDMLTGLIEMHLSLSQARTNDVISYLTIVSVIFMPLTFLVGVWGM
NFSPDASPWNMPELRSYYGYPAALVFMLLVAIGLIAFFKWKKWL
>Mature_363_residues
AKADAVKRRAPAKTRRPPVGASPGTLIADPAARRSELRLTLISPEKFKTIDNASIDDLNVHCDRWPVVWLDCTGLANIPL
IEEIGRIFNLHPLALEDVVNTDQRPKVDFFEDHAFVVVRMIDDVTAHRYEQIAVFFGKNFVVTFQEREGDPFDPVRKRIG
SSAPNRLRTRGADYLAYALIDAIVDSYFPPVEAAGDQVDGIEDEMLHSTHKHQMRQLHELRRDANVLKGVLWPMRDALAT
LIRNDVPYVKAETKVFLNDTLDHSLRLIELVETQRDMLTGLIEMHLSLSQARTNDVISYLTIVSVIFMPLTFLVGVWGMN
FSPDASPWNMPELRSYYGYPAALVFMLLVAIGLIAFFKWKKWL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=303, Percent_Identity=24.7524752475248, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 41382; Mature: 41251

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKADAVKRRAPAKTRRPPVGASPGTLIADPAARRSELRLTLISPEKFKTIDNASIDDLN
CCCHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCCCEEEEEECCHHHHHCCCCCCCCCE
VHCDRWPVVWLDCTGLANIPLIEEIGRIFNLHPLALEDVVNTDQRPKVDFFEDHAFVVVR
EEECCCCEEEEECCCCCCCCHHHHHHHHHCCCCHHHHHHHCCCCCCCCCEECCCCEEHHH
MIDDVTAHRYEQIAVFFGKNFVVTFQEREGDPFDPVRKRIGSSAPNRLRTRGADYLAYAL
HHHHHHHHHHHHHHHEECCCEEEEEECCCCCCCHHHHHHHCCCCCHHHHHCCHHHHHHHH
IDAIVDSYFPPVEAAGDQVDGIEDEMLHSTHKHQMRQLHELRRDANVLKGVLWPMRDALA
HHHHHHHCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLIRNDVPYVKAETKVFLNDTLDHSLRLIELVETQRDMLTGLIEMHLSLSQARTNDVISY
HHHHCCCCCEEECCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTIVSVIFMPLTFLVGVWGMNFSPDASPWNMPELRSYYGYPAALVFMLLVAIGLIAFFKW
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
KKWL
HHCC
>Mature Secondary Structure 
AKADAVKRRAPAKTRRPPVGASPGTLIADPAARRSELRLTLISPEKFKTIDNASIDDLN
CCHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCCCEEEEEECCHHHHHCCCCCCCCCE
VHCDRWPVVWLDCTGLANIPLIEEIGRIFNLHPLALEDVVNTDQRPKVDFFEDHAFVVVR
EEECCCCEEEEECCCCCCCCHHHHHHHHHCCCCHHHHHHHCCCCCCCCCEECCCCEEHHH
MIDDVTAHRYEQIAVFFGKNFVVTFQEREGDPFDPVRKRIGSSAPNRLRTRGADYLAYAL
HHHHHHHHHHHHHHHEECCCEEEEEECCCCCCCHHHHHHHCCCCCHHHHHCCHHHHHHHH
IDAIVDSYFPPVEAAGDQVDGIEDEMLHSTHKHQMRQLHELRRDANVLKGVLWPMRDALA
HHHHHHHCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLIRNDVPYVKAETKVFLNDTLDHSLRLIELVETQRDMLTGLIEMHLSLSQARTNDVISY
HHHHCCCCCEEECCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTIVSVIFMPLTFLVGVWGMNFSPDASPWNMPELRSYYGYPAALVFMLLVAIGLIAFFKW
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
KKWL
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]