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The map label for this gene is adrA [H]

Identifier: 13474502

GI number: 13474502

Start: 4315438

End: 4316688

Strand: Direct

Name: adrA [H]

Synonym: mlr5400

Alternate gene names: 13474502

Gene position: 4315438-4316688 (Clockwise)

Preceding gene: 13474491

Following gene: 13474504

Centisome position: 61.33

GC content: 63.55

Gene sequence:

>1251_bases
ATGCTCCAGGAGCATCCGCCGGAAATACCAGCGCCTTCCGCCGACGATCTGCGCGAGGCCGCGCGGCTCCTGGCCGTCGA
GCGCTTCGATGTTTTGGACACGCCGCGCGAAGCGCCGTTCGACCGCATCGCGCGCTTGATCAAGATGGTCTTCGATGTCC
CGATCGCCATCGTCTCGGTCATTGACGGGCACCGCCAATGGTACAAGGCCTGCGAGGGGCTGGCGATCAATGAAGTCGAA
CGCAAGGCCACATTCTGCCAGTACACGATCCTTCAGGAAGAGCCGCTGATCGTCACCGACGCGACCAAGGATCCCCGTTT
CGCCGACAATCCGATGGTCAGGAATGATCCGCATATCCGCTTCTACGCAGGCGTGCCTTTGCGAAGCCGCGACGGCCACA
ACATCGGCAGTGTCTGCGCGATCGGCTATATCCCGCGGGAATTCAGCGACCGCGACATCGCAATCCTCCAGGATTTTGCC
GATCTTGCCATGGATGAGCTGGAGCTGCGCCAGCATGCCTCCAGCGACGCGGTGACCGGCGTGCTGTCGCGGCGGGCCTT
CATCGACCAGGGCGGCAAGGCATTTGCGCTTGCGCGGCGCCAGCGCTTCGATTTCTCCTGCATCGTCTTCGATGTCGACC
ATTTCAAATCGGTCAACGACAATTTCGGGCATGCCGCAGGCGACAAGGTTCTGAGTGGCGTGGGCCGGCAATGCGGTGCC
GCCTTGCGCGACGTCGACATATTCGGACGCGTCGGTGGTGAGGAATTCGCGGTGCTTCTCTACACCGGTCGCAACGGTGC
GCTTGAATCCGCAGAGCGGCTGCGCGGCACCATCGAGACCATGCGGATCACGCACGGCGCACAGGAGATGCAGGTCACTG
CCAGCTTCGGCGTTGCCTCGTTCGATCCGGCGACCAGCGGCCTGCCGGAACTGATCGAGCGCGCCGACGCCGCCATGTAC
CGCTCGAAGCACGCCGGCCGCAATCGGATCACAGCCTGGAATTCCGCTGGGAGCGATCAGGCGCCGCCGCGGCGCAGGGT
GCTGAAGGCCGGACAGATCGTCTTCAACGCCCGCATGTCGACCATCGACTGCACGGTTCGCAGCCTTGGCGAGGATGGCG
CCACTATCGACGTGTCGAACATCTCCGGCATTCCCGGCCAGTTCGTGCTGGCCATCCGGGCGGATAGGTTCGAGACGAAA
TGCCGGGTCGTCGCCCAGGCTGAAAGGCGTCTGGAACTCGCCTTCGAGTGA

Upstream 100 bases:

>100_bases
GTGAATGGCGACAGAAAGCAATAACCAATTGATAATATTTGGCTTGCCATCATGGTCGATGCGGGTATCGCGGCGGGGGC
GCCGAAGATAGGTGGTTCGC

Downstream 100 bases:

>100_bases
GCGGCCCCGCGGCGGTCCCGATCACGCGAAGCGCCGAAGCCTATTTGTCGACCAGGTTCAGGATGTTGCCGTCCGGGTCC
TTGAACCATGCGACCTTCAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MLQEHPPEIPAPSADDLREAARLLAVERFDVLDTPREAPFDRIARLIKMVFDVPIAIVSVIDGHRQWYKACEGLAINEVE
RKATFCQYTILQEEPLIVTDATKDPRFADNPMVRNDPHIRFYAGVPLRSRDGHNIGSVCAIGYIPREFSDRDIAILQDFA
DLAMDELELRQHASSDAVTGVLSRRAFIDQGGKAFALARRQRFDFSCIVFDVDHFKSVNDNFGHAAGDKVLSGVGRQCGA
ALRDVDIFGRVGGEEFAVLLYTGRNGALESAERLRGTIETMRITHGAQEMQVTASFGVASFDPATSGLPELIERADAAMY
RSKHAGRNRITAWNSAGSDQAPPRRRVLKAGQIVFNARMSTIDCTVRSLGEDGATIDVSNISGIPGQFVLAIRADRFETK
CRVVAQAERRLELAFE

Sequences:

>Translated_416_residues
MLQEHPPEIPAPSADDLREAARLLAVERFDVLDTPREAPFDRIARLIKMVFDVPIAIVSVIDGHRQWYKACEGLAINEVE
RKATFCQYTILQEEPLIVTDATKDPRFADNPMVRNDPHIRFYAGVPLRSRDGHNIGSVCAIGYIPREFSDRDIAILQDFA
DLAMDELELRQHASSDAVTGVLSRRAFIDQGGKAFALARRQRFDFSCIVFDVDHFKSVNDNFGHAAGDKVLSGVGRQCGA
ALRDVDIFGRVGGEEFAVLLYTGRNGALESAERLRGTIETMRITHGAQEMQVTASFGVASFDPATSGLPELIERADAAMY
RSKHAGRNRITAWNSAGSDQAPPRRRVLKAGQIVFNARMSTIDCTVRSLGEDGATIDVSNISGIPGQFVLAIRADRFETK
CRVVAQAERRLELAFE
>Mature_416_residues
MLQEHPPEIPAPSADDLREAARLLAVERFDVLDTPREAPFDRIARLIKMVFDVPIAIVSVIDGHRQWYKACEGLAINEVE
RKATFCQYTILQEEPLIVTDATKDPRFADNPMVRNDPHIRFYAGVPLRSRDGHNIGSVCAIGYIPREFSDRDIAILQDFA
DLAMDELELRQHASSDAVTGVLSRRAFIDQGGKAFALARRQRFDFSCIVFDVDHFKSVNDNFGHAAGDKVLSGVGRQCGA
ALRDVDIFGRVGGEEFAVLLYTGRNGALESAERLRGTIETMRITHGAQEMQVTASFGVASFDPATSGLPELIERADAAMY
RSKHAGRNRITAWNSAGSDQAPPRRRVLKAGQIVFNARMSTIDCTVRSLGEDGATIDVSNISGIPGQFVLAIRADRFETK
CRVVAQAERRLELAFE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=174, Percent_Identity=35.632183908046, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI87081881, Length=183, Percent_Identity=37.1584699453552, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI87081977, Length=310, Percent_Identity=26.7741935483871, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI87082007, Length=171, Percent_Identity=36.8421052631579, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI1787802, Length=200, Percent_Identity=35, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI145693134, Length=172, Percent_Identity=32.5581395348837, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1787262, Length=180, Percent_Identity=33.8888888888889, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788381, Length=246, Percent_Identity=29.2682926829268, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787816, Length=206, Percent_Identity=27.6699029126214, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1787541, Length=161, Percent_Identity=31.6770186335404, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788085, Length=170, Percent_Identity=30.5882352941176, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR007894 [H]

Pfam domain/function: PF00990 GGDEF; PF05230 MASE2 [H]

EC number: NA

Molecular weight: Translated: 46007; Mature: 46007

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQEHPPEIPAPSADDLREAARLLAVERFDVLDTPREAPFDRIARLIKMVFDVPIAIVSV
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IDGHRQWYKACEGLAINEVERKATFCQYTILQEEPLIVTDATKDPRFADNPMVRNDPHIR
HHHHHHHHHHHCCCCHHHHHHHHHHHEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCEE
FYAGVPLRSRDGHNIGSVCAIGYIPREFSDRDIAILQDFADLAMDELELRQHASSDAVTG
EEECCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHH
VLSRRAFIDQGGKAFALARRQRFDFSCIVFDVDHFKSVNDNFGHAAGDKVLSGVGRQCGA
HHHHHHHHHCCCCEEEHHHHHCCCCEEEEEEHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
ALRDVDIFGRVGGEEFAVLLYTGRNGALESAERLRGTIETMRITHGAQEMQVTASFGVAS
HHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHEEEEEECCCCC
FDPATSGLPELIERADAAMYRSKHAGRNRITAWNSAGSDQAPPRRRVLKAGQIVFNARMS
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHCCEEEECCCH
TIDCTVRSLGEDGATIDVSNISGIPGQFVLAIRADRFETKCRVVAQAERRLELAFE
HHHHHHHHCCCCCCEEEECCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHEEECCC
>Mature Secondary Structure
MLQEHPPEIPAPSADDLREAARLLAVERFDVLDTPREAPFDRIARLIKMVFDVPIAIVSV
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IDGHRQWYKACEGLAINEVERKATFCQYTILQEEPLIVTDATKDPRFADNPMVRNDPHIR
HHHHHHHHHHHCCCCHHHHHHHHHHHEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCEE
FYAGVPLRSRDGHNIGSVCAIGYIPREFSDRDIAILQDFADLAMDELELRQHASSDAVTG
EEECCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHH
VLSRRAFIDQGGKAFALARRQRFDFSCIVFDVDHFKSVNDNFGHAAGDKVLSGVGRQCGA
HHHHHHHHHCCCCEEEHHHHHCCCCEEEEEEHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
ALRDVDIFGRVGGEEFAVLLYTGRNGALESAERLRGTIETMRITHGAQEMQVTASFGVAS
HHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHEEEEEECCCCC
FDPATSGLPELIERADAAMYRSKHAGRNRITAWNSAGSDQAPPRRRVLKAGQIVFNARMS
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHCCEEEECCCH
TIDCTVRSLGEDGATIDVSNISGIPGQFVLAIRADRFETKCRVVAQAERRLELAFE
HHHHHHHHCCCCCCEEEECCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]